René Leen

1.0k total citations
33 papers, 702 citations indexed

About

René Leen is a scholar working on Molecular Biology, Epidemiology and Infectious Diseases. According to data from OpenAlex, René Leen has authored 33 papers receiving a total of 702 indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 10 papers in Epidemiology and 4 papers in Infectious Diseases. Recurrent topics in René Leen's work include Biochemical and Molecular Research (6 papers), Cytomegalovirus and herpesvirus research (6 papers) and Cancer therapeutics and mechanisms (4 papers). René Leen is often cited by papers focused on Biochemical and Molecular Research (6 papers), Cytomegalovirus and herpesvirus research (6 papers) and Cancer therapeutics and mechanisms (4 papers). René Leen collaborates with scholars based in Netherlands, United States and Germany. René Leen's co-authors include André B. P. Kuilenburg, Huib N. Caron, Albert H. Gennip, Godelieve A.M. Tytgat, Arnauld Verschuur, Cees A. M. J. J. van den Hondel, G.A. van Arkel, P.A. Voûte, Ronald J. A. Wanders and C.J. Kuhlemeier and has published in prestigious journals such as Nature Communications, Biochemical Journal and FEBS Letters.

In The Last Decade

René Leen

32 papers receiving 680 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
René Leen Netherlands 16 491 72 70 62 61 33 702
Matthew Solomonson Canada 8 392 0.8× 66 0.9× 86 1.2× 106 1.7× 77 1.3× 9 822
Daniel Vyoral Czechia 19 510 1.0× 55 0.8× 67 1.0× 25 0.4× 15 0.2× 33 1.2k
Rossana Mineri Italy 14 680 1.4× 344 4.8× 85 1.2× 36 0.6× 27 0.4× 20 1.4k
Javier Garcia Barriocanal United States 9 719 1.5× 40 0.6× 43 0.6× 28 0.5× 25 0.4× 12 1.3k
Kerstin Diekert Germany 12 1.2k 2.5× 47 0.7× 68 1.0× 36 0.6× 246 4.0× 15 1.6k
Paula G. Fraenkel United States 15 424 0.9× 73 1.0× 46 0.7× 22 0.4× 112 1.8× 25 1.1k
M.Eugenia Torres-Márquez Mexico 17 670 1.4× 73 1.0× 40 0.6× 23 0.4× 36 0.6× 32 1.0k
Xiu Fen Liu United States 16 577 1.2× 85 1.2× 33 0.5× 21 0.3× 15 0.2× 19 1.1k
Juan R. Hernández‐Fernaud United Kingdom 19 465 0.9× 46 0.6× 29 0.4× 57 0.9× 7 0.1× 34 883
Sven‐A. Freibert Germany 8 374 0.8× 31 0.4× 40 0.6× 19 0.3× 186 3.0× 9 622

Countries citing papers authored by René Leen

Since Specialization
Citations

This map shows the geographic impact of René Leen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by René Leen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites René Leen more than expected).

Fields of papers citing papers by René Leen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by René Leen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by René Leen. The network helps show where René Leen may publish in the future.

Co-authorship network of co-authors of René Leen

This figure shows the co-authorship network connecting the top 25 collaborators of René Leen. A scholar is included among the top collaborators of René Leen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with René Leen. René Leen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kuilenburg, André B. P., Carla E. M. Hollak, M. Jacobs, et al.. (2023). Development of a Biosimilar of Agalsidase Beta for the Treatment of Fabry Disease: Preclinical Evaluation. Drugs in R&D. 23(2). 141–153. 4 indexed citations
2.
Reiniers, Megan J., Pim B. Olthof, Rowan F. van Golen, et al.. (2017). Hypothermic perfusion with retrograde outflow during right hepatectomy is safe and feasible. Surgery. 162(1). 48–58. 7 indexed citations
3.
Weijer, Ruud, Esther A. Zaal, René Leen, et al.. (2016). Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy. Cellular and Molecular Life Sciences. 74(6). 1133–1151. 35 indexed citations
4.
Haan, Yentl C., André B. P. Kuilenburg, René Leen, et al.. (2016). Creatine kinase inhibition lowers systemic arterial blood pressure in spontaneously hypertensive rats. Journal of Hypertension. 34(12). 2418–2426. 17 indexed citations
5.
Tytgat, Godelieve A.M., Rutger Meinsma, René Leen, et al.. (2011). Synergistic interaction between cisplatin and gemcitabine in neuroblastoma cell lines and multicellular tumor spheroids. Cancer Letters. 319(1). 23–30. 32 indexed citations
6.
Kuilenburg, André B. P., et al.. (2011). Promising effects of the 4HPR–BSO combination in neuroblastoma monolayers and spheroids. Free Radical Biology and Medicine. 51(6). 1213–1220. 9 indexed citations
7.
Leen, René, et al.. (2009). Fenretinide induces mitochondrial ROS and inhibits the mitochondrial respiratory chain in neuroblastoma. Cellular and Molecular Life Sciences. 67(5). 807–816. 48 indexed citations
8.
Tytgat, Godelieve A.M., René Leen, Pedro Brites, et al.. (2008). Pleiotropic effects of fenretinide in neuroblastoma cell lines and multicellular tumor spheroids. International Journal of Oncology. 32(5). 1011–9. 19 indexed citations
9.
Bree, Chris van, Hans M. Rodermond, René Leen, Jan Paul Medema, & André B. P. Kuilenburg. (2008). Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells. British Journal of Cancer. 98(7). 1226–1233. 4 indexed citations
10.
Schimmel, Kirsten J. M., Henk van Lenthe, René Leen, et al.. (2008). Quantitative analysis of the experimental cytotoxic drug cyclopentenyl cytosine and its metabolite in plasma with HPLC tandem mass spectrometry. Biomedical Chromatography. 22(12). 1368–1373.
11.
Bierau, Jörgen, Albert H. Gennip, René Leen, et al.. (2005). Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma. Cancer Chemotherapy and Pharmacology. 57(1). 105–113. 21 indexed citations
12.
13.
Bierau, Jörgen, René Leen, Albert H. Gennip, Huib N. Caron, & André B. P. Kuilenburg. (2004). Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography. Journal of Chromatography B. 805(2). 339–346. 13 indexed citations
14.
Verschuur, Arnauld, et al.. (2002). Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1‐β‐D‐arabinofuranosyl cytosine in a human T‐lymphoblastic cell line. International Journal of Cancer. 98(4). 616–623. 23 indexed citations
15.
Bierau, Jörgen, Albert H. Gennip, René Leen, et al.. (2002). Cyclopentenyl cytosine primes SK‐N‐BE(2)c neuroblastoma cells for cytarabine toxicity. International Journal of Cancer. 103(3). 387–392. 18 indexed citations
16.
Bierau, Jörgen, Albert H. Gennip, René Leen, Huib N. Caron, & André B. P. Kuilenburg. (2002). Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells. FEBS Letters. 527(1-3). 229–233. 5 indexed citations
17.
Verschuur, Arnauld, Albert H. Gennip, René Leen, P.A. Voûte, & André B. P. Kuilenburg. (2002). Cyclopentenyl Cytosine Induces Apoptosis and Secondary Necrosis in a T-Lymphoblastic Leukemic Cell-Line. Advances in experimental medicine and biology. 486. 319–325. 11 indexed citations
18.
Verschuur, Arnauld, et al.. (2001). Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line. Leukemia Research. 25(10). 891–900. 22 indexed citations
19.
Verschuur, Arnauld, A. H. van Gennip, René Leen, et al.. (2000). Cyclopentenyl cytosine inhibits cytidine triphosphate synthetase in paediatric acute non-lymphocytic leukaemia. European Journal of Cancer. 36(5). 627–635. 29 indexed citations
20.
Verschuur, Arnauld, Albert H. Gennip, René Leen, et al.. (2000). In vitro inhibition of cytidine triphosphate synthetase activity by cyclopentenyl cytosine in paediatric acute lymphocytic leukaemia. British Journal of Haematology. 110(1). 161–169. 34 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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