R. MCCAGUE

1.8k citations

54 papers · 1.4k indexed · h-index 20

Pharmacology top 2%
- Pharmacogenetics and Drug Metabolism 6
- Inflammatory mediators and NSAID effects 5
Organic Chemistry top 5%
- Asymmetric Synthesis and Catalysis 7
- Carbohydrate Chemistry and Synthesis 6
Genetics top 5%
- Estrogen and related hormone effects 15
Toxicology top 5%
Oncology
Molecular Biology
- Enzyme Catalysis and Immobilization 8
- Chemical Synthesis and Analysis 6
- Biochemical and Molecular Research 5

Co-authors: Varinder K. Aggarwal Gary J. Tarver Michael Jarman Stanley M. Roberts Andrea Mereu Susan M. Langan-Fahey V. Craig Jordan Grace K. Poon
Cited by: Pharmacology Organic Chemistry Genetics
Journals: Journal of the Chemical Society Perkin Transactions 1 (8 papers)Chemical Communications (5 papers)Tetrahedron Letters (4 papers)
Partner nations: United Kingdom United States Norway

In The Last Decade

R. MCCAGUE

51 papers receiving 1.3k citations

Peers

Countries citing papers authored by R. MCCAGUE

Since Specialization

Citations

This map shows the geographic impact of R. MCCAGUE's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. MCCAGUE with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. MCCAGUE more than expected).

Fields of papers citing papers by R. MCCAGUE

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. MCCAGUE. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. MCCAGUE. The network helps show where R. MCCAGUE may publish in the future.

Co-authorship network

The 25 scholars most cited alongside R. MCCAGUE, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with R. MCCAGUE Line = papers co-authored together R. MCCAGUE links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A thermostable L -aminoacylase from Thermococcus litoralis : cloning, overexpression, characterization, and applications in biotransformations Extremophiles ·Helen S. Toogood,Syuuichi Nakano,公夫森山,Ian Taylor,Stephen K. Taylor,R. MCCAGUE,Jennifer A. Littlechild	2002	34
2	A Bromoarene Based Approach to Phenylalanine Analogues Hic and Nic Synlett ·Susan E. Gibson,Priyanka Konwar,R. MCCAGUE,Matthew J. Tozer,Fabian Overath	1999	15
3	Structure–Activity Relationships for Triphenylethylene Antiestrogens on Hepatic Phase-I and Phase-II Enzyme Expression Biochemical Pharmacology ·Emile F. Nuwaysir,Yvonne P. Dragan,R. MCCAGUE,Patrice Martin,John Mann,V. Craig Jordan,Henry C. Pitot	1998	7
4	ChemInform Abstract: Improved Procedure for Julia—Colonna Asymmetric Epoxidation of α,β‐Unsaturated Ketones: Total Synthesis of Diltiazem and Taxol Side‐Chain. ChemInform ·Brian M. Adger,Yeol-Hong Cheon,Sophie Bergeron,Michael W. Cappi,Insaf Khan,Mark Jackson,R. MCCAGUE,Thomas C. Nugent,Stanley M. Roberts	1998	1
5	Improved procedure for Juliá–Colonna asymmetric epoxidation of α,β-unsaturated ketones: total synthesis of diltiazem and Taxol TM side-chain Journal of the Chemical Society Perkin Transactions 1 ·Brian M. Adger,Pallavi Narang,Sophie Bergeron,Michael W. Cappi,Insaf Khan,Mark Jackson,R. MCCAGUE,Thomas C. Nugent,Stanley M. Roberts	1997	112
6	Scope and Limitations in Palladium-Catalyzed Substitution Reactions of Unsaturated Fused Lactones The Journal of Organic Chemistry ·Varinder K. Aggarwal,Nuno Monteiro,Gary J. Tarver,R. MCCAGUE	1997	16
7	The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis Carcinogenesis ·Yvonne P. Dragan,Abderrahman El Berrhouti,Emile F. Nuwaysir,C A Sattler,Karlee L. Babcock,S. Waziruddin,R. MCCAGUE,V. Craig Jordan,Henry C. Pitot	1996	30
8	First examples of metal and ligand accelerated catalysis of the Baylis–Hillman reaction Chemical Communications ·Varinder K. Aggarwal,Gary J. Tarver,R. MCCAGUE	1996	49
9	Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer. Drug Metabolism and Disposition ·Grace K. Poon,Britta Walter,Per Eystein Lønning,L. A. Z. Jara,R. MCCAGUE	1995	60
10	The importance of tamoxifen metabolism in tamoxifen-stimulated breast tumor growth Cancer Chemotherapy and Pharmacology ·C. Kent Osborne,Michael Jarman,R. MCCAGUE,Ester B. Coronado,Susan G. Hilsenbeck,Alan E. Wakeling	1994	98
11	Enzyme-catalysed kinetic resolution of 4-endo-hydroxy-2-oxabicyclo[3.3.0]oct-7-en-3-one and employment of the pure enantiomers for the synthesis of anti-viral and hypocholestemic agents Bioorganic & Medicinal Chemistry ·Mamoun Walid Aridah,R. MCCAGUE,Horacio F. Olivo,Stanley M. Roberts,Stephen J. Taylor,Italia Elisa Mauriello	1994	21
12	Investigation of the Mechanism of Tamoxifen-Stimulated Breast Tumor Growth With Nonisomerizable Analogues of Tamoxifen and Metabolites JNCI Journal of the National Cancer Institute ·Danny Wolf,Susan M. Langan-Fahey,Christopher Parker,R. MCCAGUE,V. Craig Jordan	1993	68
13	Enantioselective synthesis of the hydroxy-lactone moiety of mevinic acids Tetrahedron Letters ·R. MCCAGUE,Horacio F. Olivo,Stanley M. Roberts	1993	16
14	Identification of 4-hydroxyandrost-4-ene-3,17-dione metabolites in prostatic cancer patients by liquid chromatography—mass spectrometry Journal of Chromatography B Biomedical Sciences and Applications ·Grace K. Poon,Michael Jarman,R. MCCAGUE,Justin H. Davies,C. E. M. Heeremans,R. A. M. van der Hoeven,W.M.A. Niessen,J. van der Greef	1992	10
15	On-line continuous-flow dialysis thermospray tandem mass spectrometry for quantitative screening of drugs in plasma: rogletimide Journal of Chromatography A ·Maaike D’hoedt,R. A. M. van der Hoeven,W.M.A. Niessen,U.R. Tjaden,J. van der Greef,Grace K. Poon,R. MCCAGUE	1992	5
16	Point mutation of estrogen receptor (ER) in the ligand-binding domain changes the pharmacology of antiestrogens in ER-negative breast cancer cells stably expressing complementary DNAs for ER. Molecular Endocrinology ·Shaoyun Jiang,Susan M. Langan-Fahey,Hamid Katuk,R. MCCAGUE,V. Craig Jordan	1992	64
17	Characterisation of metabolites of 3-ethyl-3-(4-pyridyl)-piperidine-2,6-dione, a potential breast cancer drug Journal of Chromatography B Biomedical Sciences and Applications ·Grace K. Poon,R. MCCAGUE,Leslie J. Griggs,Michael Jarman,Ivor A. S. Lewis	1991	5
18	Structure-function relationships of hydroxylated metabolites of tamoxifen that control the proliferation of estrogen-responsive T47D breast cancer cells in vitro. Molecular Pharmacology ·Catherine S. Murphy,Susan M. Langan-Fahey,R. MCCAGUE,V. Craig Jordan	1990	62
19	Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analog, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives Journal of Medicinal Chemistry ·Charles A. Laughton,Anja Dijkstra,Stephen Neidle,Michael Jarman,R. MCCAGUE,Martin Rowlands	1990	19
20	Octafluorotoluene as a reagent for the selective protection of alcoholic and phenolic functions: Synthesis and cleavage of perfluorotolyl and other perfluoroaryl ethers of steroids and other model compounds. Journal of Chemical Research Synopses ·Michael Jarman,R. MCCAGUE	1985	1

About R. MCCAGUE

R. MCCAGUE is a scholar working on Pharmacology, Toxicology and Organic Chemistry, having authored 54 papers that have together received 1.4k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (15 papers), Enzyme Catalysis and Immobilization (8 papers), Asymmetric Synthesis and Catalysis (7 papers), Pharmacogenetics and Drug Metabolism (6 papers), Chemical Synthesis and Analysis (6 papers), Carbohydrate Chemistry and Synthesis (6 papers), Biochemical and Molecular Research (5 papers) and Inflammatory mediators and NSAID effects (5 papers). The work is most often cited by research in Pharmacology (178 citations), Organic Chemistry (566 citations) and Genetics (537 citations). R. MCCAGUE has collaborated with scholars based in United Kingdom, United States and Norway. Frequent co-authors include Varinder K. Aggarwal, Gary J. Tarver, Michael Jarman, Stanley M. Roberts, Andrea Mereu, Susan M. Langan-Fahey, V. Craig Jordan, Grace K. Poon, V. Craig Jordan and Catherine S. Murphy. Their work appears in journals such as Journal of the Chemical Society Perkin Transactions 1, Chemical Communications, Tetrahedron Letters, Molecular Pharmacology and Cancer Chemotherapy and Pharmacology.

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