Prem Ponka

14.0k citations

147 papers · 11.2k indexed · 2 hit papers · h-index 52

Impact in

Hematology top 0.1%
- Iron Metabolism and Disorders
Genetics top 0.1%
- Hemoglobinopathies and Related Disorders

Papers in

Hematology 84
- Iron Metabolism and Disorders 81
Genetics 72
- Hemoglobinopathies and Related Disorders 70

Co-authors: Des R. Richardson Alex D. Sheftel Robert E. Fleming Megan Whitnall Chun Nam Lok Mark J. Koury C. Beaumont Philippe Gros
Journals: Blood (49 papers)Journal of Biological Chemistry (8 papers)Proceedings of the National Academy of Sciences (8 papers)Experimental Hematology (7 papers)Biochemical Journal (6 papers)
Partner nations: Canada United States Australia

In The Last Decade

Prem Ponka

143 papers receiving 11.0k citations

Hit Papers

align trajectories log scale

Iron Overload in Human Disease 2012 · 456 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 New England Journal of Medicine
1997 Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes

Peers

Replace Kostas Pantopoulos with:

Kostas Pantopoulos Canada

Gaetano Cairo Italy

Evan H. Morgan Australia

Z. Ioav Cabantchik Israel

Tracey A. Rouault United States

Sonia Levi Italy

Marianne Wessling‐Resnick United States

Seppo Parkkila Finland

Des R. Richardson Australia

William S. Sly United States

Prem Ponka relative to Kostas Pantopoulos Canada Kostas Pantopoulos's profile →

Citations per field

00.5×1.6×

Kostas Pantopoulos · 1×

×1.0 5k/4k

HEMAT

×1.3 3k/2k

GENET

×1.2 4k/3k

ND

×1.3 4k/3k

MB

×1.5 826/551

CB

Citations per year

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Countries citing papers authored by Prem Ponka

Since Specialization

Citations

This map shows the geographic impact of Prem Ponka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Prem Ponka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Prem Ponka more than expected).

Fields of papers citing papers by Prem Ponka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Prem Ponka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Prem Ponka. The network helps show where Prem Ponka may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Prem Ponka, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Prem Ponka Line = papers co-authored together Prem Ponka links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load Blood ·Carine Fillebeen, Márcia Teixeira de Souza, John Wagner, Angeliki Katsarou, Jeannie Mui, Hojatollah Vali, Daniel Garcia‐Santos, Prem Ponka, John F. Presley, Kostas Pantopoulos	2018	83
2	Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model Blood ·Daniel Garcia‐Santos, Amel Hamdi, Hyeon-Joo Cho, Carine Fillebeen, Kostas Pantopoulos, Monika Horváthová, Prem Ponka	2017	34
3	Erythroid cells use endosome-derived iron via the direct interaction of endosomes with mitochondria for heme synthesis Experimental Hematology ·Tariq Roshan, Daniel Garcia‐Santos, Marc Mikhael, Anne B. Mason, Alex D. Sheftel, Prem Ponka	2014	1
4	Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes Cancer Research ·David B. Lovejoy, Patric J. Jansson, Ulf T. Brunk, Jacky Wong, Prem Ponka, Des R. Richardson	2011	267
5	Molecular basis of hereditary iron homeostasis defects Hematology ·Monika Horváthová, Prem Ponka, Vladimír Divoký	2010	7
6	Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling Experimental Hematology ·Shan Soe-Lin, Sameer Apte, Marc Mikhael, Adhi Wiyata, Guangjun Nie, Prem Ponka	2010	57
7	Overexpression of Mitochondrial Ferritin Sensitizes Cells to Oxidative Stress Via an Iron-Mediated Mechanism Antioxidants and Redox Signaling ·Zhongbing Lu, Guangjun Nie, Yiye Li, Shan Soe-Lin, Yi Tao, Yuanlin Cao, Zhiyong Zhang, Nianqing Liu, Prem Ponka, Baolu Zhao	2009	23
8	Ceruloplasmin Protects Injured Spinal Cord from Iron-Mediated Oxidative Damage Journal of Neuroscience ·Khizr I. Rathore, Bradley J. Kerr, Adriana Redensek, Rubén López‐Vales, Suh Young Jeong, Prem Ponka, Samuel David	2008	80
9	Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms Experimental Hematology ·An‐Sheng Zhang, François Canonne‐Hergaux, Samantha Gruenheid, Philippe Gros, Prem Ponka	2008	18
10	A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics Proceedings of the National Academy of Sciences ·Megan Whitnall, Jonathan Howard, Prem Ponka, Des R. Richardson	2006	436
11	The anemia of “haemoglobin-deficit” (hbd/hbd) mice is caused by a defect in transferrin cycling Experimental Hematology ·An‐Sheng Zhang, Alex D. Sheftel, Prem Ponka	2006	28
12	Lipophilicity of analogs of pyridoxal isonicotinoyl hydrazone (PIH) determines the efflux of iron complexes and toxicity in K562 cells Biochemical Pharmacology ·Joan L. Buss, Gaia Pagano, Bhushan Dattatray Kamble, Prem Ponka	2003	35
13	Cardiac troponin T following repeated administration of pyridoxal isonicotinoyl hydrazone in rabbits Physiological Research ·Michaela Adamcová, Rafaela Fernanda Melo, Vladimír Geršl, V. Pelouch, Tomáš Šimůnek, Claire Trickey, Radomír Hrdina, Prem Ponka	2002	8
14	The prolyl 4‐hydroxylase inhibitor ethyl‐3,4‐dihydroxybenzoate generates effective iron deficiency in cultured cells FEBS Letters ·Jian Wang, Joan L. Buss, Guohua Chen, Prem Ponka, Kostas Pantopoulos	2002	35
15	Nitric Oxide-Mediated Modulation of Iron Regulatory Proteins: Implication for Cellular Iron Homeostasis Blood Cells Molecules and Diseases ·Sang-Won Kim, Prem Ponka	2002	38
16	Development of potential iron chelators for the treatment of Friedreich’s ataxia: ligands that mobilize mitochondrial iron Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Des R. Richardson, H. Wihlm, Prem Ponka, E. Becker	2001	76
17	Development of iron chelators to treat iron overload disease and their use as experimental tools to probe intracellular iron metabolism American Journal of Hematology ·Des R. Richardson, Prem Ponka	1998	76
18	Identification of a mechanism of iron uptake by cells which is stimulated by hydroxyl radicals generated via the iron-catalysed Haber-Weiss reaction Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Des R. Richardson, Prem Ponka	1995	46
19	Deoxyribose degradation catalyzed by Fe(III)-EDTA: kinetic aspects and potential usefulness for submicromolar iron measurements Molecular and Cellular Biochemistry ·Marcelo Hermes‐Lima, Чаварри Гальвес Николь Зойла Флор, Herbert M. Schulman, Kenneth B. Storey, Prem Ponka	1994	34
20	Regulation of heme biosynthesis: Distinct regulatory features in erythroid cells Stem Cells ·Prem Ponka, Herbert M. Schulman	1993	22

About Prem Ponka

Prem Ponka is a scholar working on Hematology, Genetics, Nutrition and Dietetics, Physiology and Molecular Biology, having authored 147 papers that have together received 11.2k indexed citations. Recurring topics across this work include Iron Metabolism and Disorders (81 papers), Hemoglobinopathies and Related Disorders (70 papers), Trace Elements in Health (46 papers), Erythrocyte Function and Pathophysiology (31 papers), Heme Oxygenase-1 and Carbon Monoxide (22 papers), Neonatal Health and Biochemistry (16 papers), Mitochondrial Function and Pathology (10 papers) and Porphyrin Metabolism and Disorders (9 papers). The work is most often cited by research in Hematology (4.5k citations), Genetics (3.0k citations), Nutrition and Dietetics (3.5k citations), Molecular Biology (4.2k citations) and Cell Biology (826 citations). Prem Ponka has collaborated with scholars based in Canada, United States and Australia. Frequent co-authors include Des R. Richardson, Alex D. Sheftel, Robert E. Fleming, Megan Whitnall, Chun Nam Lok, Mark J. Koury, C. Beaumont, Philippe Gros, François Canonne‐Hergaux and E. Becker. Their work appears in journals such as Blood, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Experimental Hematology and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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