Philip Needleman

25.3k total citations · 9 hit papers
263 papers, 20.8k citations indexed

About

Philip Needleman is a scholar working on Pharmacology, Biochemistry and Molecular Biology. According to data from OpenAlex, Philip Needleman has authored 263 papers receiving a total of 20.8k indexed citations (citations by other indexed papers that have themselves been cited), including 100 papers in Pharmacology, 93 papers in Biochemistry and 81 papers in Molecular Biology. Recurrent topics in Philip Needleman's work include Inflammatory mediators and NSAID effects (97 papers), Eicosanoids and Hypertension Pharmacology (87 papers) and Nitric Oxide and Endothelin Effects (34 papers). Philip Needleman is often cited by papers focused on Inflammatory mediators and NSAID effects (97 papers), Eicosanoids and Hypertension Pharmacology (87 papers) and Nitric Oxide and Endothelin Effects (34 papers). Philip Needleman collaborates with scholars based in United States, United Kingdom and Japan. Philip Needleman's co-authors include Mark G. Currie, Jaime L. Masferrer, Karen Seibert, Amiram Raz, Barbara A. Jakschik, Aubrey R. Morrison, Mark S. Minkes, J B Lefkowith, David M. Geller and A Raz and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Philip Needleman

262 papers receiving 19.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ARACHIDONIC ACID METABOLISM

1986 1.5k citations Philip Needleman, Barbara A. Jakschik et al. profile →
Nitric oxide activates cyclooxygenase enzymes.

1993 1.2k citations Jaime L. Masferrer, Karen Seibert et al. profile →
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.

1990 784 citations Jaime L. Masferrer, Karen Seibert et al. Journal of Biological Chemistry profile →
Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian Atria

1983 629 citations Mark G. Currie, David M. Geller et al. profile →
Triene prostaglandins: Prostacyclin and thromboxane biosynthesis and unique biological properties

1979 623 citations Philip Needleman, Amiram Raz et al. profile →
Purification and Sequence Analysis of Bioactive Atrial Peptides (Atriopeptins)

1984 460 citations Mark G. Currie, David M. Geller et al. profile →
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides

1976 425 citations Philip Needleman, Salvador Moncada et al. profile →
MECHANISM OF TOLERANCE DEVELOPMENT TO ORGANIC NITRATES

1973 386 citations Philip Needleman et al. Journal of Pharmacology and Experimental Therapeutics profile →
: A selective inhibitor of thromboxane synthetase

1977 247 citations Salvador Moncada, Stuart Bunting et al. Prostaglandins profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Philip Needleman United States	72	6.1k	6.0k	5.7k	4.4k	4.1k	263	20.8k
Thomas M. Coffman United States	72	3.7k 0.6×	6.4k 1.1×	6.6k 1.2×	1.8k 0.4×	2.5k 0.6×	253	20.3k
Philip W. Majerus United States	88	2.5k 0.4×	11.3k 1.9×	2.7k 0.5×	1.8k 0.4×	1.9k 0.5×	231	22.9k
Jane A. Mitchell United Kingdom	66	5.4k 0.9×	4.6k 0.8×	2.9k 0.5×	3.0k 0.7×	5.9k 1.4×	268	19.1k
Christoph Thiemermann United Kingdom	84	2.5k 0.4×	7.8k 1.3×	2.7k 0.5×	3.7k 0.8×	7.1k 1.7×	434	26.1k
Timothy D. Warner United Kingdom	58	3.5k 0.6×	3.9k 0.7×	4.1k 0.7×	2.4k 0.5×	6.3k 1.5×	252	15.5k
Matthew D. Breyer United States	70	4.3k 0.7×	6.6k 1.1×	1.9k 0.3×	3.2k 0.7×	2.6k 0.6×	204	16.0k
Paul M. Vanhoutte Hong Kong	89	2.1k 0.3×	7.5k 1.2×	9.1k 1.6×	6.3k 1.4×	15.8k 3.8×	432	29.7k
Raymond C. Harris United States	82	3.1k 0.5×	8.6k 1.4×	3.0k 0.5×	3.0k 0.7×	2.5k 0.6×	334	22.5k
E.A. Higgs United Kingdom	21	1.4k 0.2×	4.1k 0.7×	3.7k 0.7×	3.1k 0.7×	10.6k 2.6×	28	19.2k
Fumitaka Ushikubi Japan	52	6.3k 1.0×	4.5k 0.8×	1.3k 0.2×	2.3k 0.5×	2.5k 0.6×	125	13.4k

Countries citing papers authored by Philip Needleman

Since Specialization

Citations

This map shows the geographic impact of Philip Needleman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip Needleman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip Needleman more than expected).

Fields of papers citing papers by Philip Needleman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip Needleman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip Needleman. The network helps show where Philip Needleman may publish in the future.

Co-authorship network of co-authors of Philip Needleman

This figure shows the co-authorship network connecting the top 25 collaborators of Philip Needleman. A scholar is included among the top collaborators of Philip Needleman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philip Needleman. Philip Needleman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Needleman, Philip. (2001). From a Twinkle in the Eye to a Blockbuster Drug. Research-Technology Management. 44(6). 38. 4 indexed citations

Obukowicz, Mark G., et al.. (1998). Identification and Characterization of a Novel Δ6/Δ5 Fatty Acid Desaturase Inhibitor As a Potential Anti-Inflammatory Agent. Biochemical Pharmacology. 55(7). 1045–1058. 48 indexed citations

Isakson, Peter C., et al.. (1995). Discovery of a better aspirin.. PubMed. 23. 49–54. 21 indexed citations

Saper, Clifford B., Melina R. Kibbe, Karen M. Hurley, et al.. (1990). Brain natriuretic peptide-like immunoreactive innervation of the cardiovascular and cerebrovascular systems in the rat.. Circulation Research. 67(6). 1345–1354. 47 indexed citations

Thorén, Peter, Allyn L. Mark, Donald A. Morgan, et al.. (1986). Activation of vagal depressor reflexes by atriopeptins inhibits renal sympathetic nerve activity. American Journal of Physiology-Heart and Circulatory Physiology. 251(6). H1252–H1259. 100 indexed citations

Lefkowith, J B, et al.. (1985). Paradoxical conservation of cardiac and renal arachidonate content in essential fatty acid deficiency.. Journal of Biological Chemistry. 260(29). 15736–15744. 112 indexed citations

Needleman, Philip, S P Adams, Barbara R. Cole, et al.. (1985). Atriopeptins as cardiac hormones.. Hypertension. 7(4). 469–482. 341 indexed citations

Evers, Alex S. & Philip Needleman. (1984). ENDOGENOUSLY PRODUCED LEUKOTRIENES CAUSE VASOCONSTRICTION IN INFARCTED RABBIT HEARTS. Anesthesiology. 61(3). A88–A88. 3 indexed citations

Oshima, Takeshi, Edward R. McCluskey, Akiko Honda, & Philip Needleman. (1984). Pharmacological manipulation of canine cyclooxygenase and thromboxane synthetase in vivo: differential renal and platelet recovery rates.. Journal of Pharmacology and Experimental Therapeutics. 229(2). 598–602. 7 indexed citations

10.

Elliott, W.J., et al.. (1984). Arachidonic acid metabolism by rabbit fetal membranes of various gestational ages. Prostaglandins. 27(1). 27–36. 16 indexed citations

11.

Yates, Jesse, et al.. (1983). Effects of prostacyclin on short-circuit current and water flow in the toad urinary bladder. American Journal of Physiology-Renal Physiology. 244(3). F270–F277. 3 indexed citations

12.

DeSchryver, Katherine, et al.. (1983). Metabolic and cellular alterations underlying the exaggerated renal prostaglandin and thromboxane synthesis in ureter obstruction in rabbits. Inflammatory response involving fibroblasts and mononuclear cells.. Journal of Clinical Investigation. 71(1). 81–90. 84 indexed citations

13.

Smith, William L., Thomas G. Bell, & Philip Needleman. (1979). Increased renal tubular synthesis of prostaglandins in the rabbit kidney in response to ureteral obstruction. Prostaglandins. 18(2). 269–277. 20 indexed citations

14.

Hsueh, Wei, et al.. (1978). Lipases and prostaglandin biosynthesis.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 3. 113–20. 18 indexed citations

15.

Isakson, Peter C., et al.. (1977). Prostaglandins and the renin-angiotensin system in canine endotoxemia.. Journal of Pharmacology and Experimental Therapeutics. 200(3). 614–622. 15 indexed citations

16.

Needleman, Philip. (1976). The synthesis and function of prostaglandins in the heart.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 35(12). 2376–81. 76 indexed citations

17.

Moncada, Salvador, Philip Needleman, Stuart Bunting, & John R. Vane. (1976). Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition. Prostaglandins. 12(3). 323–335. 126 indexed citations

18.

Blumberg, A L, et al.. (1976). Work in progress: Angiotensin III - induced prostaglandin (PG) release. Prostaglandins. 11(1). 195–197. 18 indexed citations

19.

Needleman, Philip, et al.. (1974). RELEASE OF RENAL PROSTAGLANDIN BY CATECHOLAMINES: RELATIONSHIP TO RENAL ENDOCRINE FUNCTION. Journal of Pharmacology and Experimental Therapeutics. 188(2). 453–460. 95 indexed citations

20.

Needleman, Philip, et al.. (1969). RELATIONSHIP BETWEEN GLUTATHIONE-DEPENDENT DENITRATION AND THE VASODILATOR EFFECTIVENESS OF ORGANIC NITRATES. Journal of Pharmacology and Experimental Therapeutics. 165(2). 286–288. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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