Peter J. Roughley

24.0k total citations · 2 hit papers
276 papers, 18.6k citations indexed

About

Peter J. Roughley is a scholar working on Rheumatology, Cell Biology and Molecular Biology. According to data from OpenAlex, Peter J. Roughley has authored 276 papers receiving a total of 18.6k indexed citations (citations by other indexed papers that have themselves been cited), including 147 papers in Rheumatology, 129 papers in Cell Biology and 83 papers in Molecular Biology. Recurrent topics in Peter J. Roughley's work include Proteoglycans and glycosaminoglycans research (128 papers), Osteoarthritis Treatment and Mechanisms (125 papers) and Spine and Intervertebral Disc Pathology (64 papers). Peter J. Roughley is often cited by papers focused on Proteoglycans and glycosaminoglycans research (128 papers), Osteoarthritis Treatment and Mechanisms (125 papers) and Spine and Intervertebral Disc Pathology (64 papers). Peter J. Roughley collaborates with scholars based in Canada, United States and United Kingdom. Peter J. Roughley's co-authors include John S. Mort, Michael A. Adams, John Antoniou, Robert J. White, Mauro Alini, Francis H. Glorieux, Frank Rauch, Johanne Martel‐Pelletier, Jean‐Pierre Pelletier and Lee I. Melching and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Peter J. Roughley

275 papers receiving 18.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

What is Intervertebral Disc Degeneration, and What Causes It?

2006 1.3k citations Peter J. Roughley et al. profile →
Biology of Intervertebral Disc Aging and Degeneration

2004 595 citations Peter J. Roughley profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Peter J. Roughley Canada	79	7.2k	6.0k	4.9k	4.3k	4.3k	276	18.6k
Sergio A. Jiménez United States	78	5.6k 0.8×	6.1k 1.0×	1.3k 0.3×	2.2k 0.5×	6.0k 1.4×	390	20.9k
Bruce Caterson United Kingdom	68	5.8k 0.8×	1.4k 0.2×	1.8k 0.4×	4.6k 1.1×	4.0k 0.9×	243	13.8k
Christopher B. Little Australia	60	6.6k 0.9×	1.6k 0.3×	2.8k 0.6×	1.4k 0.3×	3.2k 0.7×	264	12.7k
Danny Chan Hong Kong	58	2.3k 0.3×	3.7k 0.6×	2.7k 0.6×	963 0.2×	3.2k 0.7×	259	11.0k
Wim B. van den Berg Netherlands	99	16.3k 2.3×	1.1k 0.2×	3.9k 0.8×	1.4k 0.3×	10.8k 2.5×	451	32.9k
David R. Eyre United States	68	6.5k 0.9×	1.1k 0.2×	1.2k 0.2×	1.7k 0.4×	4.1k 1.0×	232	15.7k
Gideon A. Rodan United States	91	4.4k 0.6×	1.1k 0.2×	1.3k 0.3×	1.5k 0.4×	14.6k 3.4×	262	26.3k
A. Robin Poole Canada	64	8.9k 1.2×	506 0.1×	2.3k 0.5×	2.0k 0.5×	3.3k 0.8×	163	15.0k
Mary B. Goldring United States	73	14.5k 2.0×	506 0.1×	4.6k 0.9×	1.6k 0.4×	8.0k 1.9×	226	23.3k
Koji Hashimoto Japan	60	2.2k 0.3×	2.2k 0.4×	1.5k 0.3×	1.3k 0.3×	4.3k 1.0×	288	15.4k

Countries citing papers authored by Peter J. Roughley

Since Specialization

Citations

This map shows the geographic impact of Peter J. Roughley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter J. Roughley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter J. Roughley more than expected).

Fields of papers citing papers by Peter J. Roughley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter J. Roughley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter J. Roughley. The network helps show where Peter J. Roughley may publish in the future.

Co-authorship network of co-authors of Peter J. Roughley

This figure shows the co-authorship network connecting the top 25 collaborators of Peter J. Roughley. A scholar is included among the top collaborators of Peter J. Roughley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Peter J. Roughley. Peter J. Roughley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Moffatt, Pierre, et al.. (2017). Absence of the dermatan sulfate chain of decorin does not affect mouse development. Journal of Negative Results in BioMedicine. 16(1). 7–7. 5 indexed citations

Vadalà, Gianluca, Fabrizio Russo, Girish Pattappa, et al.. (2015). A Nucleotomy Model with Intact Annulus Fibrosus to Test Intervertebral Disc Regeneration Strategies. Tissue Engineering Part C Methods. 21(11). 1117–1124. 24 indexed citations

Walter, Benjamin A., Morakot Likhitpanichkul, Svenja Illien‐Jünger, et al.. (2015). TNFα Transport Induced by Dynamic Loading Alters Biomechanics of Intact Intervertebral Discs. PLoS ONE. 10(3). e0118358–e0118358. 37 indexed citations

Mwale, Fackson, Hong Wang, Peter J. Roughley, John Antoniou, & Lisbet Haglund. (2014). Link N and Mesenchymal Stem Cells Can Induce Regeneration of the Early Degenerate Intervertebral Disc. Tissue Engineering Part A. 20(21-22). 2942–2949. 47 indexed citations

Önnerfjord, Patrik, Rahul Gawri, Jean Ouellet, et al.. (2013). Chondroadherin Fragmentation Mediated by the Protease HTRA1 Distinguishes Human Intervertebral Disc Degeneration from Normal Aging. Journal of Biological Chemistry. 288(26). 19280–19287. 36 indexed citations

Purmessur, Devina, Benjamin A. Walter, Peter J. Roughley, et al.. (2013). A role for TNFα in intervertebral disc degeneration: A non-recoverable catabolic shift. Biochemical and Biophysical Research Communications. 433(1). 151–156. 165 indexed citations

Stokes, Ian A. F., Carole McBride, David D. Aronsson, & Peter J. Roughley. (2013). Metabolic Effects of Angulation, Compression, and Reduced Mobility on Annulus Fibrosis in a Model of Altered Mechanical Environment in Scoliosis. Spine Deformity. 1(3). 161–170. 11 indexed citations

Rauch, Frank, Pierre Moffatt, Moira Cheung, et al.. (2012). Osteogenesis imperfecta type V: marked phenotypic variability despite the presence of the IFITM5 c.−14C>T mutation in all patients. Journal of Medical Genetics. 50(1). 21–24. 86 indexed citations

Antoniou, John, et al.. (2012). The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells. Arthritis Research & Therapy. 14(6). R267–R267. 25 indexed citations

10.

Haglund, Lisbet, et al.. (2011). Development of a Bioreactor for Axially Loaded Intervertebral Disc Organ Culture. Tissue Engineering Part C Methods. 17(10). 1011–1019. 62 indexed citations

11.

Rauch, Frank, Liljana Lalic, Peter J. Roughley, & Francis H. Glorieux. (2010). Genotype–phenotype correlations in nonlethal osteogenesis imperfecta caused by mutations in the helical domain of collagen type I. European Journal of Human Genetics. 18(6). 642–647. 71 indexed citations

12.

Durigova, Michaela, Peter J. Roughley, & John S. Mort. (2007). Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M. Osteoarthritis and Cartilage. 16(1). 98–104. 51 indexed citations

13.

Liu, Chunhong, Yasuhito Hayashi, James V. Jester, et al.. (2004). Excess Biglycan Interferes with TGF– Signaling Required for Eyelid Morphogenesis. Investigative Ophthalmology & Visual Science. 45(13). 712–712. 2 indexed citations

14.

Burton‐Wurster, Nancy, G. Matthews, G. Lust, et al.. (2003). TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage. Osteoarthritis and Cartilage. 11(3). 167–176. 30 indexed citations

15.

Venkatesan, Narayanan, et al.. (2000). Alterations in Large and Small Proteoglycans in Bleomycin-Induced Pulmonary Fibrosis in Rats. American Journal of Respiratory and Critical Care Medicine. 161(6). 2066–2073. 58 indexed citations

16.

Little, Christopher B., Carl R. Flannery, Clare Hughes, et al.. (1999). Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro. Biochemical Journal. 344(1). 61–68. 151 indexed citations

17.

Korenberg, Julie R., et al.. (1993). Assignment of the Human Aggrecan Gene (AGC1) to 15q26 Using Fluorescence in Situ Hybridization Analysis. Genomics. 16(2). 546–548. 42 indexed citations

18.

Roughley, Peter J. & Robert J. White. (1992). The dermatan sulfate proteoglycans of the adult human meniscus. Journal of Orthopaedic Research®. 10(5). 631–637. 36 indexed citations

19.

Nguyen, Quang K., et al.. (1990). Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B.. PubMed. 266(2). 569–73. 79 indexed citations

20.

Mort, John S., Bruce Caterson, A. Robin Poole, & Peter J. Roughley. (1985). The origin of human cartilage proteoglycan link-protein heterogeneity and fragmentation during aging. Biochemical Journal. 232(3). 805–812. 39 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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