Nikolaos A. Afratis

2.8k total citations · 1 hit paper
27 papers, 2.1k citations indexed

About

Nikolaos A. Afratis is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Nikolaos A. Afratis has authored 27 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 12 papers in Cell Biology and 8 papers in Oncology. Recurrent topics in Nikolaos A. Afratis's work include Proteoglycans and glycosaminoglycans research (12 papers), Glycosylation and Glycoproteins Research (11 papers) and Protease and Inhibitor Mechanisms (6 papers). Nikolaos A. Afratis is often cited by papers focused on Proteoglycans and glycosaminoglycans research (12 papers), Glycosylation and Glycoproteins Research (11 papers) and Protease and Inhibitor Mechanisms (6 papers). Nikolaos A. Afratis collaborates with scholars based in Greece, Israel and France. Nikolaos A. Afratis's co-authors include Nikos K. Karamanos, Achilleas D. Theocharis, Dragana Nikitovic, Spyros S. Skandalis, George N. Tzanakakis, Chrysostomi Gialeli, Zoi Piperigkou, Demitrios H. Vynios, Mauro S.G. Pavão and Evgenia Karousou and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Molecular Biology and Advanced Drug Delivery Reviews.

In The Last Decade

Nikolaos A. Afratis

26 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A guide to the composition and functions of the extracellular matrix

2021 613 citations Nikos K. Karamanos, Achilleas D. Theocharis et al. FEBS Journal profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nikolaos A. Afratis Greece	16	1.0k	824	396	367	249	27	2.1k
Zoi Piperigkou Greece	27	1.2k 1.2×	849 1.0×	590 1.5×	638 1.7×	292 1.2×	61	2.9k
Evgenia Karousou Italy	28	1.6k 1.5×	1.6k 1.9×	491 1.2×	294 0.8×	262 1.1×	63	2.8k
Aikaterini Berdiaki Greece	27	879 0.8×	730 0.9×	300 0.8×	317 0.9×	188 0.8×	55	1.6k
Juliane Winkler Germany	15	1.8k 1.7×	633 0.8×	428 1.1×	668 1.8×	154 0.6×	20	2.9k
Constantinos M. Mikelis United States	26	1.3k 1.2×	389 0.5×	415 1.0×	453 1.2×	193 0.8×	75	2.2k
Laurent Duca France	28	1.1k 1.0×	393 0.5×	649 1.6×	326 0.9×	233 0.9×	65	2.8k
Anthony Calabro United States	31	1.7k 1.7×	1.6k 1.9×	265 0.7×	347 0.9×	241 1.0×	78	3.5k
Patrizio Castagnola Italy	27	1.3k 1.3×	384 0.5×	429 1.1×	404 1.1×	361 1.4×	96	3.0k
Vasiliki Gkretsi Cyprus	24	722 0.7×	543 0.7×	262 0.7×	498 1.4×	318 1.3×	57	1.9k
Hinke A.B. Multhaupt Denmark	30	1.6k 1.5×	1.3k 1.5×	529 1.3×	462 1.3×	427 1.7×	62	3.2k

Countries citing papers authored by Nikolaos A. Afratis

Since Specialization

Citations

This map shows the geographic impact of Nikolaos A. Afratis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nikolaos A. Afratis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nikolaos A. Afratis more than expected).

Fields of papers citing papers by Nikolaos A. Afratis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nikolaos A. Afratis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nikolaos A. Afratis. The network helps show where Nikolaos A. Afratis may publish in the future.

Co-authorship network of co-authors of Nikolaos A. Afratis

This figure shows the co-authorship network connecting the top 25 collaborators of Nikolaos A. Afratis. A scholar is included among the top collaborators of Nikolaos A. Afratis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nikolaos A. Afratis. Nikolaos A. Afratis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Afratis, Nikolaos A., et al.. (2025). From Structure to Function: The Impact of EGFR and IGF-IR in 3D Breast Cancer Spheroids. Cancers. 17(16). 2606–2606. 3 indexed citations

Afratis, Nikolaos A., et al.. (2025). Allosteric Anti-KLK4 Antibody Development for Targeted Anti-cancer Effects in Ovarian Carcinoma. Journal of Molecular Biology. 437(20). 169101–169101.

Arvaniti, Olga S., et al.. (2024). Bactrocera oleae Control and Smart Farming Technologies for Olive Orchards in the Context of Optimal Olive Oil Quality: A Review. Agronomy. 14(11). 2586–2586. 2 indexed citations

Klepfish, Mordehay, Nikolaos A. Afratis, Eli Brazowski, et al.. (2020). LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis. Frontiers in Immunology. 11. 480–480. 40 indexed citations

Afratis, Nikolaos A. & Irit Sagi. (2019). Novel Approaches for Extracellular Matrix Targeting in Disease Treatment. Methods in molecular biology. 1952. 261–275. 11 indexed citations

Afratis, Nikolaos A., Moisés Selman, Annie Pardo, & Irit Sagi. (2018). Emerging insights into the role of matrix metalloproteases as therapeutic targets in fibrosis. Matrix Biology. 68-69. 167–179. 39 indexed citations

Afratis, Nikolaos A., Mordehay Klepfish, Nikos K. Karamanos, & Irit Sagi. (2018). The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery. Advanced Drug Delivery Reviews. 129. 4–15. 56 indexed citations

Afratis, Nikolaos A., Panagiotis Bouris, Spyros S. Skandalis, et al.. (2017). IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules. Scientific Reports. 7(1). 40138–40138. 35 indexed citations

Afratis, Nikolaos A., Κωνσταντίνα Καραμάνου, Zoi Piperigkou, Demitrios H. Vynios, & Achilleas D. Theocharis. (2016). The role of heparins and nano-heparins as therapeutic tool in breast cancer. Glycoconjugate Journal. 34(3). 299–307. 31 indexed citations

10.

Vivès, Romain R., Amal Seffouh, Nikolaos A. Afratis, et al.. (2015). Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma. Cellular Signalling. 27(10). 2054–2067. 20 indexed citations

11.

Theocharis, Achilleas D., Spyros S. Skandalis, Thomas Neill, et al.. (2015). Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1855(2). 276–300. 132 indexed citations

12.

Piperigkou, Zoi, Κωνσταντίνα Καραμάνου, Nikolaos A. Afratis, et al.. (2015). Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules. Toxicology Letters. 240(1). 32–42. 19 indexed citations

13.

Bouris, Panagiotis, Spyros S. Skandalis, Zoi Piperigkou, et al.. (2015). Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells. Matrix Biology. 43. 42–60. 145 indexed citations

14.

Afratis, Nikolaos A., et al.. (2014). Syndecans as Modulators and Potential Pharmacological Targets in Cancer Progression. Frontiers in Oncology. 4. 4–4. 77 indexed citations

15.

Malavaki, Christina J., et al.. (2014). Validated Capillary Electrophoretic Assays for Disaccharide Composition Analysis of Galactosaminoglycans in Biologic Samples and Drugs/Nutraceuticals. Methods in molecular biology. 1229. 129–141. 1 indexed citations

16.

Skandalis, Spyros S., Nikolaos A. Afratis, Dragana Nikitovic, et al.. (2013). Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: Focus on the role and impact of proteoglycans. Matrix Biology. 35. 182–193. 88 indexed citations

17.

Skandalis, Spyros S., Alexios J. Aletras, Chrysostomi Gialeli, et al.. (2012). Targeting the Tumor Proteasome as a Mechanism to Control the Synthesis and Bioactivity of Matrix Macromolecules. Current Molecular Medicine. 12(8). 1068–1082. 14 indexed citations

18.

Afratis, Nikolaos A., Chrysostomi Gialeli, Dragana Nikitovic, et al.. (2012). Glycosaminoglycans: key players in cancer cell biology and treatment. FEBS Journal. 279(7). 1177–1197. 433 indexed citations

19.

Kouvidi, Katerina, Aikaterini Berdiaki, Dragana Nikitovic, et al.. (2011). Role of Receptor for Hyaluronic Acid-mediated Motility (RHAMM) in Low Molecular Weight Hyaluronan (LMWHA)-mediated Fibrosarcoma Cell Adhesion. Journal of Biological Chemistry. 286(44). 38509–38520. 115 indexed citations

20.

Afratis, Nikolaos A., Anastasia Spiliopoulou, Christina J. Malavaki, et al.. (2010). A modified protocol for isolation and purity evaluation of a staphylococcal acidic polysaccharide by chromatography and capillary electrophoresis. Biomedical Chromatography. 25(5). 531–534. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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