Nancy C. Horton

2.5k total citations · 1 hit paper
49 papers, 2.0k citations indexed

About

Nancy C. Horton is a scholar working on Molecular Biology, Genetics and Epidemiology. According to data from OpenAlex, Nancy C. Horton has authored 49 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Molecular Biology, 15 papers in Genetics and 9 papers in Epidemiology. Recurrent topics in Nancy C. Horton's work include DNA and Nucleic Acid Chemistry (25 papers), RNA and protein synthesis mechanisms (18 papers) and Bacterial Genetics and Biotechnology (13 papers). Nancy C. Horton is often cited by papers focused on DNA and Nucleic Acid Chemistry (25 papers), RNA and protein synthesis mechanisms (18 papers) and Bacterial Genetics and Biotechnology (13 papers). Nancy C. Horton collaborates with scholars based in United States, United Kingdom and India. Nancy C. Horton's co-authors include Mitchell Lewis, John J. Perona, Ponzy Lu, Michele A. Kercher, Maria A. Schumacher, Helen C. Pace, Richard G. Brennan, Geoffrey Chang, B.C. Finzel and Chad K. Park and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Nancy C. Horton

47 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer

1996 636 citations Mitchell Lewis, Geoffrey Chang et al. Science profile →

Peers

Nancy C. Horton

GENET

ECOLO

Michael I. Recht United States

Susan E. Tsutakawa United States

G.V.T. Swapna United States

Alexei A. Adzhubei Russia

Frédéric Dardel France

Ray Yu‐Ruei Wang United States

Michael J. Osborne Canada

Jayati Sengupta India

Katsuo Katayanagi Japan

Joyce H.G. Lebbink Netherlands

Michael I. Recht United States

Nancy C. Horton

1.8k ×1.0

383 ×0.7

GENET

136 ×0.4

251 ×1.3

ECOLO

115 ×0.9

Citations per year, relative to Nancy C. Horton Nancy C. Horton (= 1×) peers Michael I. Recht

Countries citing papers authored by Nancy C. Horton

Since Specialization

Citations

This map shows the geographic impact of Nancy C. Horton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nancy C. Horton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nancy C. Horton more than expected).

Fields of papers citing papers by Nancy C. Horton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nancy C. Horton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nancy C. Horton. The network helps show where Nancy C. Horton may publish in the future.

Co-authorship network of co-authors of Nancy C. Horton

This figure shows the co-authorship network connecting the top 25 collaborators of Nancy C. Horton. A scholar is included among the top collaborators of Nancy C. Horton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nancy C. Horton. Nancy C. Horton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Horton, Nancy C., et al.. (2022). High-Resolution Structure of the Nuclease Domain of the Human Parvovirus B19 Main Replication Protein NS1. Journal of Virology. 96(9). e0216421–e0216421. 5 indexed citations

Lyumkis, Dmitry, et al.. (2022). Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity. Journal of Biological Chemistry. 298(4). 101760–101760. 4 indexed citations

Polley, Smarajit, Dmitry Lyumkis, & Nancy C. Horton. (2019). Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease. Structure. 27(10). 1497–1507.e3. 10 indexed citations

Park, Chad K., et al.. (2018). The run-on oligomer filament enzyme mechanism of SgrAI: Part 1. Assembly kinetics of the run-on oligomer filament. Journal of Biological Chemistry. 293(38). 14585–14598. 6 indexed citations

Piperakis, Michael M., Richard Cosstick, Chad K. Park, et al.. (2015). Probing the Run-On Oligomer of Activated SgrAI Bound to DNA. PLoS ONE. 10(4). e0124783–e0124783. 11 indexed citations

Lyumkis, Dmitry, Chad K. Park, Florence Tama, et al.. (2013). Allosteric Regulation of DNA Cleavage and Sequence-Specificity through Run-On Oligomerization. Structure. 21(10). 1848–1858. 18 indexed citations

Park, Chad K., Hemant Joshi, Alka Agrawal, et al.. (2010). Domain Swapping in Allosteric Modulation of DNA Specificity. PLoS Biology. 8(12). e1000554–e1000554. 15 indexed citations

Horton, Nancy C. & Chad K. Park. (2010). Crystallization of Zinc Finger Proteins Bound to DNA. Methods in molecular biology. 649. 457–477. 2 indexed citations

Dunten, Pete, et al.. (2010). New clues in the allosteric activation of DNA cleavage bySgrAI: structures ofSgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallographica Section D Biological Crystallography. 67(1). 67–74. 12 indexed citations

10.

Dunten, Pete, et al.. (2009). The restriction enzymeSgrAI: structure solutionviacombination of poor MIRAS and MR phases. Acta Crystallographica Section D Biological Crystallography. 65(4). 393–398.

11.

Horton, Nancy C., et al.. (2008). Early Interrogation and Recognition of DNA Sequence by Indirect Readout. Structure. 16(12). 1828–1837. 19 indexed citations

12.

Bitinaite, Jurate, et al.. (2008). DNA Distortion and Specificity in a Sequence-Specific Endonuclease. Journal of Molecular Biology. 383(1). 186–204. 8 indexed citations

13.

Horton, Nancy C., et al.. (2004). Mechanistic Insights from the Structures of HincII Bound to Cognate DNA Cleaved from Addition of Mg2+ and Mn2+. Journal of Molecular Biology. 343(4). 833–849. 19 indexed citations

14.

Sam, My D., Nancy C. Horton, Tracy Nissan, & John J. Perona. (2001). Catalytic efficiency and sequence selectivity of a restriction endonuclease modulated by a distal manganese ion binding site. Journal of Molecular Biology. 306(4). 851–861. 16 indexed citations

15.

Horton, Nancy C., Lydia F. Dorner, Ira Schildkraut, & John J. Perona. (1999). Crystallization and preliminary diffraction analysis of the HincII restriction endonuclease–DNA complex. Acta Crystallographica Section D Biological Crystallography. 55(11). 1943–1945. 5 indexed citations

16.

Baldwin, Eric T., Ronald W. Sarver, G. L. Bryant, et al.. (1998). Cation binding to the integrin CD11b I domain and activation model assessment. Structure. 6(7). 923–935. 61 indexed citations

17.

Horton, Nancy C. & John J. Perona. (1998). Role of protein-induced bending in the specificity of DNA recognition: crystal structure of Eco RV endonuclease complexed with d(AAAGAT) + d(ATCTT) 1 1Edited by P. E. Wright. Journal of Molecular Biology. 277(4). 779–787. 44 indexed citations

18.

Horton, Nancy C. & John J. Perona. (1998). Recognition of Flanking DNA Sequences by EcoRV Endonuclease Involves Alternative Patterns of Water-mediated Contacts. Journal of Biological Chemistry. 273(34). 21721–21729. 32 indexed citations

19.

Lewis, Mitchell, Geoffrey Chang, Nancy C. Horton, et al.. (1996). Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer. Science. 271(5253). 1247–1254. 636 indexed citations breakdown →

20.

Horton, Nancy C. & B.C. Finzel. (1996). The Structure of an RNA/DNA Hybrid: A Substrate of the Ribonuclease Activity of HIV-1 Reverse Transcriptase. Journal of Molecular Biology. 264(3). 521–533. 90 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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