Mutsuhiro Takekawa

6.1k total citations · 2 hit papers
62 papers, 5.0k citations indexed

About

Mutsuhiro Takekawa is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Mutsuhiro Takekawa has authored 62 papers receiving a total of 5.0k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Molecular Biology, 13 papers in Immunology and 11 papers in Oncology. Recurrent topics in Mutsuhiro Takekawa's work include Melanoma and MAPK Pathways (17 papers), Protein Tyrosine Phosphatases (13 papers) and Protein Kinase Regulation and GTPase Signaling (7 papers). Mutsuhiro Takekawa is often cited by papers focused on Melanoma and MAPK Pathways (17 papers), Protein Tyrosine Phosphatases (13 papers) and Protein Kinase Regulation and GTPase Signaling (7 papers). Mutsuhiro Takekawa collaborates with scholars based in Japan, United States and Vietnam. Mutsuhiro Takekawa's co-authors include Haruo Saito, Tatsuya Maeda, Hiroyuki Fukuda, Shinobu Imajoh‐Ohmi, Yuji Kubota, Takanori Nakamura, Taichiro Tomida, M Adachi, Kohsuke Imai and Francesc Posas and has published in prestigious journals such as Science, Cell and Journal of Biological Chemistry.

In The Last Decade

Mutsuhiro Takekawa

61 papers receiving 4.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Family of Stress-Inducible GADD45-like Proteins Mediate Activation of the Stress-Responsive MTK1/MEKK4 MAPKKK

1998 640 citations Mutsuhiro Takekawa, Haruo Saito Cell profile →
Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor

1995 548 citations Mutsuhiro Takekawa, Haruo Saito et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mutsuhiro Takekawa Japan	30	3.9k	1.1k	769	640	584	62	5.0k
Katsuji Yoshioka Japan	32	3.5k 0.9×	948 0.9×	760 1.0×	532 0.8×	706 1.2×	98	4.8k
Nick Morrice United Kingdom	19	3.6k 0.9×	672 0.6×	1.0k 1.3×	548 0.9×	432 0.7×	21	4.6k
Damien D’Amours Canada	25	4.0k 1.0×	2.1k 2.0×	693 0.9×	454 0.7×	490 0.8×	49	4.9k
Kiyotsugu Yoshida Japan	40	4.0k 1.0×	1.5k 1.4×	439 0.6×	580 0.9×	859 1.5×	108	5.4k
Megan J. Robinson United States	18	3.2k 0.8×	823 0.8×	522 0.7×	522 0.8×	484 0.8×	20	4.4k
Judith M. Müller Germany	32	4.4k 1.1×	744 0.7×	419 0.5×	927 1.4×	967 1.7×	42	6.0k
Shane C. Masters United States	18	6.3k 1.6×	1.2k 1.2×	807 1.0×	860 1.3×	671 1.1×	23	7.8k
Christoph Reinhard United States	20	3.6k 0.9×	709 0.7×	834 1.1×	728 1.1×	564 1.0×	35	4.7k
Peter E. Shaw United Kingdom	32	4.1k 1.1×	1.2k 1.1×	531 0.7×	724 1.1×	828 1.4×	71	5.3k
Ho Lee South Korea	33	2.8k 0.7×	582 0.5×	838 1.1×	648 1.0×	664 1.1×	157	4.1k

Countries citing papers authored by Mutsuhiro Takekawa

Since Specialization

Citations

This map shows the geographic impact of Mutsuhiro Takekawa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mutsuhiro Takekawa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mutsuhiro Takekawa more than expected).

Fields of papers citing papers by Mutsuhiro Takekawa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mutsuhiro Takekawa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mutsuhiro Takekawa. The network helps show where Mutsuhiro Takekawa may publish in the future.

Co-authorship network of co-authors of Mutsuhiro Takekawa

This figure shows the co-authorship network connecting the top 25 collaborators of Mutsuhiro Takekawa. A scholar is included among the top collaborators of Mutsuhiro Takekawa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mutsuhiro Takekawa. Mutsuhiro Takekawa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Yoshioka, Daisuke, Takanori Nakamura, Yuji Kubota, & Mutsuhiro Takekawa. (2024). Formation of the NLRP3 inflammasome inhibits stress granule assembly by multiple mechanisms. The Journal of Biochemistry. 175(6). 629–641. 3 indexed citations

Kubota, Yuji, et al.. (2023). Caspase 3‐specific cleavage of MEK1 suppresses ERK signaling and sensitizes cells to stress‐induced apoptosis. FEBS Open Bio. 13(4). 684–700. 4 indexed citations

Kubota, Yuji, et al.. (2018). Wheat Germ Agglutinin (WGA)-SDS-PAGE: A Novel Method for the Detection of O-GlcNAc-modified Proteins by Lectin Affinity Gel Electrophoresis. BIO-PROTOCOL. 8(23). e3098–e3098. 4 indexed citations

Kubota, Yuji, et al.. (2017). WGA-based lectin affinity gel electrophoresis: A novel method for the detection of O-GlcNAc-modified proteins. 1 indexed citations

Hijiya, Naoki, Yoshiyuki Tsukamoto, Chisato Nakada, et al.. (2016). Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma. Cancer Research. 76(9). 2612–2625. 45 indexed citations

Saito, Haruo, et al.. (2016). TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis. Nature Communications. 7(1). 10252–10252. 112 indexed citations

Ichikawa, Kenji, Yuji Kubota, Takanori Nakamura, et al.. (2015). MCRIP1, an ERK Substrate, Mediates ERK-Induced Gene Silencing during Epithelial-Mesenchymal Transition by Regulating the Co-Repressor CtBP. Molecular Cell. 58(1). 35–46. 62 indexed citations

Tomida, Taichiro, Mutsuhiro Takekawa, & Haruo Saito. (2015). Oscillation of p38 activity controls efficient pro-inflammatory gene expression. Nature Communications. 6(1). 8350–8350. 69 indexed citations

Otsuka, Motoyuki, Akemi Takata, Takeshi Yoshikawa, et al.. (2011). Receptor for Activated Protein Kinase C: Requirement for Efficient MicroRNA Function and Reduced Expression in Hepatocellular Carcinoma. PLoS ONE. 6(9). e24359–e24359. 21 indexed citations

10.

Tomida, Taichiro, Mutsuhiro Takekawa, P. O’Grady, & Haruo Saito. (2009). Stimulus-Specific Distinctions in Spatial and Temporal Dynamics of Stress-Activated Protein Kinase Kinase Kinases Revealed by a Fluorescence Resonance Energy Transfer Biosensor. Molecular and Cellular Biology. 29(22). 6117–6127. 23 indexed citations

11.

Nakajima, Akihito, Sachiko Komazawa‐Sakon, Mutsuhiro Takekawa, et al.. (2006). An antiapoptotic protein, c‐FLIPL, directly binds to MKK7 and inhibits the JNK pathway. The EMBO Journal. 25(23). 5549–5559. 69 indexed citations

12.

Takekawa, Mutsuhiro, Kazuo Tatebayashi, & Haruo Saito. (2005). Conserved Docking Site Is Essential for Activation of Mammalian MAP Kinase Kinases by Specific MAP Kinase Kinase Kinases. Molecular Cell. 18(3). 295–306. 124 indexed citations

13.

Itoh, Motoyuki, M Adachi, Hiroshi Yasui, et al.. (2002). Nuclear Export of Glucocorticoid Receptor is Enhanced by c-Jun N-Terminal Kinase-Mediated Phosphorylation. Molecular Endocrinology. 16(10). 2382–2392. 190 indexed citations

14.

Takekawa, Mutsuhiro. (2002). Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta. The EMBO Journal. 21(23). 6473–6482. 155 indexed citations

15.

Matsunaga, Takuya, Tadao Ishida, Mutsuhiro Takekawa, et al.. (2002). Analysis of Gene Expression During Maturation of Immature Dendritic Cells Derived from Peripheral Blood Monocytes. Scandinavian Journal of Immunology. 56(6). 593–601. 28 indexed citations

16.

Shonai, Takaharu, M Adachi, Kaori Sakata, et al.. (2002). MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells. Cell Death and Differentiation. 9(9). 963–971. 61 indexed citations

17.

Takekawa, Mutsuhiro. (2000). p53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. The EMBO Journal. 19(23). 6517–6526. 349 indexed citations

18.

Takekawa, Mutsuhiro. (1998). Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways. The EMBO Journal. 17(16). 4744–4752. 241 indexed citations

19.

Takekawa, Mutsuhiro & Haruo Saito. (1998). A Family of Stress-Inducible GADD45-like Proteins Mediate Activation of the Stress-Responsive MTK1/MEKK4 MAPKKK. Cell. 95(4). 521–530. 640 indexed citations breakdown →

20.

Takekawa, Mutsuhiro. (1997). A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways. The EMBO Journal. 16(16). 4973–4982. 157 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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