Methvin Isaac

1.8k total citations
42 papers, 1.2k citations indexed

About

Methvin Isaac is a scholar working on Molecular Biology, Organic Chemistry and Cellular and Molecular Neuroscience. According to data from OpenAlex, Methvin Isaac has authored 42 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 18 papers in Organic Chemistry and 11 papers in Cellular and Molecular Neuroscience. Recurrent topics in Methvin Isaac's work include Asymmetric Synthesis and Catalysis (9 papers), Chemical Synthesis and Analysis (8 papers) and Neuroscience and Neuropharmacology Research (7 papers). Methvin Isaac is often cited by papers focused on Asymmetric Synthesis and Catalysis (9 papers), Chemical Synthesis and Analysis (8 papers) and Neuroscience and Neuropharmacology Research (7 papers). Methvin Isaac collaborates with scholars based in Canada, United States and Italy. Methvin Isaac's co-authors include Tak Hang Chan, Leo A. Paquette, Abdelmalik Slassi, Rima Al‐awar, David Uehling, Jan Jongstra, Alessandro Datti, Michaël Prakesch, Guy A. Higgins and Curtis F. Crasto and has published in prestigious journals such as Blood, Cancer Cell and Cancer Research.

In The Last Decade

Methvin Isaac

42 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Methvin Isaac Canada 20 604 543 251 120 76 42 1.2k
Gina H. Lu United States 21 1.1k 1.9× 460 0.8× 388 1.5× 132 1.1× 44 0.6× 32 2.0k
Celia Dominguez United States 27 1.1k 1.8× 697 1.3× 412 1.6× 233 1.9× 76 1.0× 79 2.2k
J. Jeffry Howbert United States 20 804 1.3× 352 0.6× 532 2.1× 125 1.0× 66 0.9× 38 1.5k
I‐Li Chen Taiwan 21 445 0.7× 375 0.7× 131 0.5× 58 0.5× 74 1.0× 67 1.2k
Stephen R. Fletcher United States 20 941 1.6× 640 1.2× 323 1.3× 182 1.5× 45 0.6× 38 1.8k
Tien Pham Australia 19 510 0.8× 261 0.5× 222 0.9× 210 1.8× 80 1.1× 39 1.3k
Francesco G. Salituro United States 27 923 1.5× 357 0.7× 462 1.8× 186 1.6× 32 0.4× 45 1.8k
Margot W. Beukers Netherlands 27 1.0k 1.7× 410 0.8× 418 1.7× 114 0.9× 27 0.4× 42 1.9k
Mingzhang Gao United States 22 564 0.9× 494 0.9× 183 0.7× 263 2.2× 23 0.3× 89 1.6k
Tjeerd Barf Netherlands 19 724 1.2× 360 0.7× 267 1.1× 229 1.9× 77 1.0× 33 1.7k

Countries citing papers authored by Methvin Isaac

Since Specialization
Citations

This map shows the geographic impact of Methvin Isaac's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Methvin Isaac with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Methvin Isaac more than expected).

Fields of papers citing papers by Methvin Isaac

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Methvin Isaac. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Methvin Isaac. The network helps show where Methvin Isaac may publish in the future.

Co-authorship network of co-authors of Methvin Isaac

This figure shows the co-authorship network connecting the top 25 collaborators of Methvin Isaac. A scholar is included among the top collaborators of Methvin Isaac based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Methvin Isaac. Methvin Isaac is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wong, Jong Fu, Carlos Zepeda‐Velázquez, Laurent Hoffer, et al.. (2024). Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of Medicinal Chemistry. 67(6). 4707–4725. 3 indexed citations
2.
Uehling, David, Babu Joseph, Kim Chan Chung, et al.. (2021). Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma. Journal of Medicinal Chemistry. 64(15). 11129–11147. 16 indexed citations
3.
Gwynne, William D., Adele Girgis-Gabardo, Kwang H. Kim, et al.. (2020). Antagonists of the serotonin receptor 5A target human breast tumor initiating cells. BMC Cancer. 20(1). 724–724. 15 indexed citations
4.
Smil, David, Carlos Zepeda‐Velázquez, Dimitrios Panagopoulos, et al.. (2020). Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma. Journal of Medicinal Chemistry. 63(9). 4978–4996. 15 indexed citations
5.
Babichev, Yael, Alessandro Datti, David Uehling, et al.. (2016). PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma. Journal of Translational Medicine. 14(1). 67–67. 42 indexed citations
6.
Raboisson, Patrick, Anna Breitholtz‐Emanuelsson, Louise Edwards, et al.. (2012). Discovery and characterization of AZD9272 and AZD6538—Two novel mGluR5 negative allosteric modulators selected for clinical development. Bioorganic & Medicinal Chemistry Letters. 22(22). 6974–6979. 29 indexed citations
7.
Enwere, Emeka K., Methvin Isaac, David Uehling, et al.. (2012). TWEAK and cIAP1 Regulate Myoblast Fusion Through the Noncanonical NF-κB Signaling Pathway. Science Signaling. 5(246). ra75–ra75. 67 indexed citations
8.
Grinshtein, Natalie, Alessandro Datti, David Uehling, et al.. (2011). Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells. Cancer Research. 71(4). 1385–1395. 76 indexed citations
9.
Mahoney, Douglas J., Charles Lefebvre, J Brun, et al.. (2011). Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death. Cancer Cell. 20(4). 443–456. 77 indexed citations
10.
Isaac, Methvin, et al.. (2011). The oncogenic PIM kinase family regulates drug resistance through multiple mechanisms. Drug Resistance Updates. 14(4-5). 203–211. 53 indexed citations
11.
Higgins, Guy A., Nathalie Breysse, Elijus Undzys, et al.. (2009). The anti-epileptic drug lacosamide (Vimpat®) has anxiolytic property in rodents. European Journal of Pharmacology. 624(1-3). 1–9. 19 indexed citations
12.
Fletcher, Paul, Maria Tampakeras, Judy Sinyard, et al.. (2009). Characterizing the effects of 5-HT2C receptor ligands on motor activity and feeding behaviour in 5-HT2C receptor knockout mice. Neuropharmacology. 57(3). 259–267. 66 indexed citations
13.
Slassi, Abdelmalik, Methvin Isaac, Louise Edwards, et al.. (2005). Recent Advances in Non-Competitive mGlu5 Receptor Antagonists and their Potential Therapeutic Applications. Current Topics in Medicinal Chemistry. 5(9). 897–911. 42 indexed citations
14.
Isaac, Methvin, Louise Edwards, Julie M. Wilson, et al.. (2003). Design, synthesis and biological activity of novel dimethyl-{2-[6-substituted-indol-1-yl]-ethyl}-amine as potent, selective, and orally-Bioavailable 5-HT 1D agonists. Bioorganic & Medicinal Chemistry Letters. 13(24). 4409–4413. 5 indexed citations
15.
Isaac, Methvin, Angela Naismith, Julie M. Wilson, et al.. (2002). 1-(Bicyclopiperazinyl)ethylindoles and 1-(homopiperazinyl)ethyl-indoles as highly selective and potent 5-HT7 receptor ligands. Bioorganic & Medicinal Chemistry Letters. 12(17). 2451–2454. 9 indexed citations
16.
Isaac, Methvin, et al.. (2001). 5,5-Diaryl-2-amino-4-pentenoates as novel, potent, and selective glycine transporter type-2 reuptake inhibitors. Bioorganic & Medicinal Chemistry Letters. 11(11). 1371–1373. 21 indexed citations
17.
Isaac, Methvin, et al.. (2001). Synthesis of chiral and geometrically defined 5,5-diaryl-2-amino-4-pentenoates: novel amino acid derivatives. Tetrahedron Letters. 42(16). 2957–2960. 7 indexed citations
18.
Slassi, Abdelmalik, et al.. (2001). Novel serotonergic and non-serotonergic migraine headache therapies. Expert Opinion on Therapeutic Patents. 11(4). 625–649. 8 indexed citations
19.
Isaac, Methvin, Abdelmalik Slassi, Julie M. Wilson, et al.. (2000). 6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 10(15). 1719–1721. 13 indexed citations
20.
Isaac, Methvin, Abdelmalik Slassi, Louise Edwards, et al.. (2000). Pyrrolo[3,2,1- ij ]quinoline derivatives, a 5-HT 2c receptor agonist with selectivity over the 5-HT 2a receptor: potential therapeutic applications for epilepsy and obesity. Bioorganic & Medicinal Chemistry Letters. 10(9). 919–921. 37 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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