Max Costa

26.1k total citations · 5 hit papers
314 papers, 19.5k citations indexed

About

Max Costa is a scholar working on Molecular Biology, Health, Toxicology and Mutagenesis and Cancer Research. According to data from OpenAlex, Max Costa has authored 314 papers receiving a total of 19.5k indexed citations (citations by other indexed papers that have themselves been cited), including 173 papers in Molecular Biology, 113 papers in Health, Toxicology and Mutagenesis and 89 papers in Cancer Research. Recurrent topics in Max Costa's work include Trace Elements in Health (59 papers), Heavy Metal Exposure and Toxicity (56 papers) and Chromium effects and bioremediation (53 papers). Max Costa is often cited by papers focused on Trace Elements in Health (59 papers), Heavy Metal Exposure and Toxicity (56 papers) and Chromium effects and bioremediation (53 papers). Max Costa collaborates with scholars based in United States, China and Italy. Max Costa's co-authors include Qingdong Ke, Catherine B. Klein, Konstantin Salnikow, Hong Sun, Thomas Kluz, Haobin Chen, Qiao Yi Chen, Anatoly Zhitkovich, Adriana Arita and Yana Chervona and has published in prestigious journals such as Science, Journal of Biological Chemistry and SHILAP Revista de lepidopterología.

In The Last Decade

Max Costa

313 papers receiving 18.8k citations

Hit Papers

Hypoxia-Inducible Factor-1 (HIF-1) 1997 2026 2006 2016 2006 2006 1997 2019 2021 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Hypoxia-Inducible Factor-1 (HIF-1)
    2006 1.3k citations Max Costa et al. profile →
  2. Toxicity and Carcinogenicity of Chromium Compounds in Humans
    2006 720 citations Max Costa, Catherine B. Klein profile →
  3. Toxicity and Carcinogenicity of Cr(VI) in Animal Models and Humans
    1997 496 citations Max Costa profile →
  4. Mechanisms of chromium-induced toxicity
    2019 331 citations Max Costa et al. profile →
  5. Arsenic: A Global Environmental Challenge
    2021 225 citations Max Costa et al. profile →

Peers

Max Costa
Xianglin Shi United States
Martyn T. Smith United States
Michael P. Waalkes United States
Andrew Collins Norway
Paul B. Tchounwou United States
Michael Fenech Australia
Zongwei Cai Hong Kong
Habibul Ahsan United States
Steffen Loft Denmark
A. Hartwig Germany
Xianglin Shi United States
Max Costa
Citations per year, relative to Max Costa Max Costa (= 1×) peers Xianglin Shi

Countries citing papers authored by Max Costa

Since Specialization
Citations

This map shows the geographic impact of Max Costa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Max Costa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Max Costa more than expected).

Fields of papers citing papers by Max Costa

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Max Costa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Max Costa. The network helps show where Max Costa may publish in the future.

Co-authorship network of co-authors of Max Costa

This figure shows the co-authorship network connecting the top 25 collaborators of Max Costa. A scholar is included among the top collaborators of Max Costa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Max Costa. Max Costa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Park, Sun Young, Fengyuan Gao, Lingbing Li, et al.. (2024). Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling. Oncogene. 43(12). 899–917. 12 indexed citations
2.
Wang, Po‐Shun, Zulong Liu, Abdullah F. U. H. Saeed, et al.. (2024). Hexavalent chromium exposure activates the non-canonical nuclear factor kappa B pathway to promote immune checkpoint protein programmed death-ligand 1 expression and lung carcinogenesis. Cancer Letters. 589. 216827–216827. 10 indexed citations
3.
Shakya, Aryatara, Pengfei Liu, Matthew Dodson, et al.. (2023). The NRF2-p97-NRF2 negative feedback loop. Redox Biology. 65. 102839–102839. 15 indexed citations
4.
Liu, Shan & Max Costa. (2022). The role of NUPR1 in response to stress and cancer development. Toxicology and Applied Pharmacology. 454. 116244–116244. 26 indexed citations
5.
Roy, Nirmal, et al.. (2021). Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel. Oncology Reports. 45(4). 10 indexed citations
6.
Costa, Max & Angélica Ortiz. (2020). The Toxicity of Carcinogenic Metals to the Brain. Journal of Carcinogenesis & Mutagenesis. 11(4). 1–11. 4 indexed citations
7.
Costa, Max, et al.. (2020). Nuclear protein 1 imparts oncogenic potential and chemotherapeutic resistance in cancer. Cancer Letters. 494. 132–141. 23 indexed citations
8.
Harrison, Roy M., Dimitrios Bousiotis, Abdulrahman K. Alkhalaf, et al.. (2017). Health risk associated with airborne particulate matter and its components in Jeddah, Saudi Arabia. The Science of The Total Environment. 590-591. 531–539. 42 indexed citations
9.
Howe, Caitlin G., Xinhua Liu, Megan N. Hall, et al.. (2016). Sex-Specific Associations between One-Carbon Metabolism Indices and Posttranslational Histone Modifications in Arsenic-Exposed Bangladeshi Adults. Cancer Epidemiology Biomarkers & Prevention. 26(2). 261–269. 17 indexed citations
10.
Muñoz, Alexandra & Max Costa. (2013). Nutritionally Mediated Oxidative Stress and Inflammation. Oxidative Medicine and Cellular Longevity. 2013. 1–11. 152 indexed citations
11.
Arita, Adriana, Alexandra Muñoz, Yana Chervona, et al.. (2012). Gene Expression Profiles in Peripheral Blood Mononuclear Cells of Chinese Nickel Refinery Workers with High Exposures to Nickel and Control Subjects. Cancer Epidemiology Biomarkers & Prevention. 22(2). 261–269. 23 indexed citations
12.
Zhou, Xue, Hong Sun, Haobin Chen, et al.. (2010). Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase. Cancer Research. 70(10). 4214–4221. 103 indexed citations
13.
Yang, Yali, Jingxiang Bai, Rulong Shen, et al.. (2008). Polo-like Kinase 3 Functions as a Tumor Suppressor and Is a Negative Regulator of Hypoxia-Inducible Factor-1α under Hypoxic Conditions. Cancer Research. 68(11). 4077–4085. 99 indexed citations
14.
Sun, Hong, Xue Zhou, Haobin Chen, Qin Li, & Max Costa. (2008). Modulation of histone methylation by hexavalent chromium. Cancer Research. 68. 6–6. 3 indexed citations
15.
Salnikow, Konstantin, Mikhail V. Blagosklonny, Helen Ryan, Randall S. Johnson, & Max Costa. (2000). Carcinogenic nickel induces genes involved with hypoxic stress.. PubMed. 60(1). 38–41. 149 indexed citations
16.
Salnikow, Konstantin, et al.. (2000). Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism.. PubMed. 60(13). 3375–8. 164 indexed citations
17.
Salnikow, Konstantin, Max Costa, William D. Figg, & Mikhail V. Blagosklonny. (2000). Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.. PubMed. 60(20). 5630–4. 70 indexed citations
18.
Broday, Limor, Yong‐Woo Lee, & Max Costa. (1999). 5-Azacytidine Induces Transgene Silencing by DNA Methylation in Chinese Hamster Cells. Molecular and Cellular Biology. 19(4). 3198–3204. 23 indexed citations
19.
Salnikow, Konstantin, et al.. (1998). Cap43, a novel gene specifically induced by Ni2+ compounds.. PubMed. 58(10). 2182–9. 202 indexed citations
20.
Klein, Catherine B., B. Kargačin, Konstantin Salnikow, et al.. (1995). Carcinogenic Nickel Silences Gene Expression by Chromatin Condensation and DNA Methylation: a New Model for Epigenetic Carcinogens. Molecular and Cellular Biology. 15(5). 2547–2557. 282 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Xianglin Shi Breakdown of academic impact, for papers by Martyn T. Smith Breakdown of academic impact, for papers by Michael P. Waalkes Breakdown of academic impact, for papers by Andrew Collins Breakdown of academic impact, for papers by Paul B. Tchounwou Breakdown of academic impact, for papers by Michael Fenech Breakdown of academic impact, for papers by Zongwei Cai Breakdown of academic impact, for papers by Habibul Ahsan Breakdown of academic impact, for papers by Steffen Loft Breakdown of academic impact, for papers by A. Hartwig
Rankless by CCL
2026