Mason W. Freeman

19.1k total citations · 9 hit papers
104 papers, 14.9k citations indexed

About

Mason W. Freeman is a scholar working on Molecular Biology, Surgery and Immunology. According to data from OpenAlex, Mason W. Freeman has authored 104 papers receiving a total of 14.9k indexed citations (citations by other indexed papers that have themselves been cited), including 47 papers in Molecular Biology, 38 papers in Surgery and 33 papers in Immunology. Recurrent topics in Mason W. Freeman's work include Cholesterol and Lipid Metabolism (22 papers), Atherosclerosis and Cardiovascular Diseases (15 papers) and Immune Response and Inflammation (15 papers). Mason W. Freeman is often cited by papers focused on Cholesterol and Lipid Metabolism (22 papers), Atherosclerosis and Cardiovascular Diseases (15 papers) and Immune Response and Inflammation (15 papers). Mason W. Freeman collaborates with scholars based in United States, Germany and Canada. Mason W. Freeman's co-authors include Kathryn J. Moore, Monty Krieger, Douglas T. Golenbock, Lucia Rohrer, Tatsuhiko Kodama, Michael L. Fitzgerald, Lorna P. Andersson, Bruce M. Spiegelman, Evan D. Rosen and John T. Potts and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Mason W. Freeman

104 papers receiving 14.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

2000 1.3k citations Mason W. Freeman, Douglas T. Golenbock et al. profile →
C/EBPα induces adipogenesis through PPARγ: a unified pathway

2002 1.2k citations Mason W. Freeman et al. profile →
A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide

1991 978 citations Mason W. Freeman et al. profile →
Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 876 citations Mason W. Freeman et al. profile →
Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages

2002 818 citations Vidya Kunjathoor, Maria Febbraio et al. Journal of Biological Chemistry profile →
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.

1992 817 citations Mason W. Freeman et al. profile →
Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

2004 503 citations Vidya Kunjathoor, Kathryn J. Moore et al. profile →
Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease

2015 312 citations Mason W. Freeman et al. profile →
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension

2022 202 citations Mason W. Freeman, Yuan‐Di C. Halvorsen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mason W. Freeman United States	51	6.1k	5.0k	3.1k	2.5k	2.3k	104	14.9k
Myron I. Cybulsky Canada	57	5.9k 1.0×	8.4k 1.7×	2.7k 0.9×	2.1k 0.8×	1.6k 0.7×	129	18.2k
Theo J.C. van Berkel Netherlands	68	6.7k 1.1×	4.1k 0.8×	4.9k 1.6×	2.4k 1.0×	2.4k 1.0×	317	15.8k
Stephen M. Prescott United States	89	9.1k 1.5×	6.1k 1.2×	4.8k 1.6×	2.3k 0.9×	2.3k 1.0×	233	25.6k
Maria Febbraio United States	71	9.2k 1.5×	5.5k 1.1×	3.1k 1.0×	3.6k 1.4×	1.5k 0.6×	170	19.0k
Thomas M. McIntyre United States	89	10.1k 1.7×	5.8k 1.2×	3.7k 1.2×	3.1k 1.2×	1.9k 0.8×	240	26.2k
Alexander N. Orekhov Russia	57	5.5k 0.9×	4.6k 0.9×	2.7k 0.9×	1.8k 0.7×	804 0.4×	478	13.6k
Roy L. Silverstein United States	79	11.7k 1.9×	7.8k 1.6×	3.3k 1.1×	3.0k 1.2×	2.2k 0.9×	209	24.0k
Koichi Tsuneyama Japan	65	3.3k 0.5×	3.1k 0.6×	3.7k 1.2×	5.3k 2.1×	2.5k 1.1×	448	15.3k
Linda K. Curtiss United States	67	4.8k 0.8×	5.8k 1.2×	5.1k 1.6×	2.3k 0.9×	1.3k 0.6×	190	15.0k
Shuichi Kaneko Japan	75	5.7k 0.9×	3.2k 0.6×	3.1k 1.0×	6.9k 2.8×	4.4k 1.9×	555	21.6k

Countries citing papers authored by Mason W. Freeman

Since Specialization

Citations

This map shows the geographic impact of Mason W. Freeman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mason W. Freeman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mason W. Freeman more than expected).

Fields of papers citing papers by Mason W. Freeman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mason W. Freeman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mason W. Freeman. The network helps show where Mason W. Freeman may publish in the future.

Co-authorship network of co-authors of Mason W. Freeman

This figure shows the co-authorship network connecting the top 25 collaborators of Mason W. Freeman. A scholar is included among the top collaborators of Mason W. Freeman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mason W. Freeman. Mason W. Freeman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Freeman, Mason W., et al.. (2024). Results from a Phase 1 Study Assessing the Pharmacokinetics of the Aldosterone Synthase Inhibitor Baxdrostat in Participants with Varying Degrees of Renal Function. Clinical Pharmacology in Drug Development. 13(4). 410–418. 10 indexed citations

Halvorsen, Yuan‐Di C., Annie L. Conery, John Paul Lock, Wenjiong Zhou, & Mason W. Freeman. (2023). Bexagliflozin as an adjunct to metformin for the treatment of type 2 diabetes in adults: A 24‐week, randomized, double‐blind, placebo‐controlled trial. Diabetes Obesity and Metabolism. 25(10). 2954–2962. 9 indexed citations

Allegretti, Andrew S., Wenbin Zhang, Wenjiong Zhou, et al.. (2019). Safety and Effectiveness of Bexagliflozin in Patients With Type 2 Diabetes Mellitus and Stage 3a/3b CKD. American Journal of Kidney Diseases. 74(3). 328–337. 58 indexed citations

Perlstein, Todd S., Samuel Z. Goldhaber, Kerrie P. Nelson, et al.. (2011). The Creating an Optimal Warfarin Nomogram (CROWN) Study. Thrombosis and Haemostasis. 107(1). 59–68. 11 indexed citations

Okuhira, Keiichiro, et al.. (2005). Purification of ATP-binding Cassette Transporter A1 and Associated Binding Proteins Reveals the Importance of β1-Syntrophin in Cholesterol Efflux. Journal of Biological Chemistry. 280(47). 39653–39664. 53 indexed citations

Fitzgerald, Michael L., Andrea L. Morris, Angeliki Chroni, et al.. (2004). ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux. Journal of Lipid Research. 45(2). 287–294. 121 indexed citations

Fitzgerald, Michael L., et al.. (2004). ATP-binding Cassette Transporter A1 Contains a Novel C-terminal VFVNFA Motif That Is Required for Its Cholesterol Efflux and ApoA-I Binding Activities. Journal of Biological Chemistry. 279(46). 48477–48485. 60 indexed citations

Kim, Woojin S., et al.. (2003). Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A. Biochemical and Biophysical Research Communications. 310(2). 542–549. 46 indexed citations

Moore, Kathryn J. & Mason W. Freeman. (2003). Embryonal Stem (ES) Cell-Derived Macrophages: A Cellular System that Facilitates the Genetic Dissection of Macrophage Function. Humana Press eBooks. 30. 343–356. 2 indexed citations

10.

Henneke, Philipp, Osamu Takeuchi, Richard Malley, et al.. (2002). Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways. The Journal of Immunology. 169(7). 3970–3977. 120 indexed citations

11.

Fitzgerald, Michael L., Kathryn J. Moore, & Mason W. Freeman. (2002). Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. Journal of Molecular Medicine. 80(5). 271–281. 56 indexed citations

12.

Moore, Kathryn J., Joseph El Khoury, Kinya Terada, et al.. (2002). A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid. Journal of Biological Chemistry. 277(49). 47373–47379. 293 indexed citations

13.

Kunjathoor, Vidya, Maria Febbraio, Eugene A. Podrez, et al.. (2002). Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages. Journal of Biological Chemistry. 277(51). 49982–49988. 818 indexed citations breakdown →

14.

Moore, Kathryn J., M. Fitzgerald, & Mason W. Freeman. (2001). Peroxisome proliferator-activated receptors in macrophage biology: friend or foe?. Current Opinion in Lipidology. 12(5). 519–527. 50 indexed citations

15.

Moore, Kathryn J., Lorna P. Andersson, Robin R. Ingalls, et al.. (2000). Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages. The Journal of Immunology. 165(8). 4272–4280. 187 indexed citations

16.

Fitzgerald, Michael L., Kathryn J. Moore, Mason W. Freeman, & Guy L. Reed. (2000). Lipopolysaccharide Induces Scavenger Receptor A Expression in Mouse Macrophages: A Divergent Response Relative to Human THP-1 Monocyte/Macrophages. The Journal of Immunology. 164(5). 2692–2700. 102 indexed citations

17.

Fabunmi, Rosalind P., Kathryn J. Moore, Peter Libby, & Mason W. Freeman. (2000). Stromelysin-1 (MMP-3) expression driven by a macrophage-specific promoter results in reduced viability in transgenic mice. Atherosclerosis. 148(2). 375–386. 2 indexed citations

18.

Freeman, Mason W.. (1997). Scavenger receptors in atherosclerosis. Current Opinion in Hematology. 4(1). 41–47. 48 indexed citations

19.

Freeman, Mason W., et al.. (1995). Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines.. Journal of Clinical Investigation. 95(1). 122–133. 153 indexed citations

20.

Freeman, Mason W.. (1994). Macrophage scavenger receptors. Current Opinion in Lipidology. 5(2). 143–148. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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