Mark P. Brynildsen

7.1k total citations · 3 hit papers
69 papers, 4.3k citations indexed

About

Mark P. Brynildsen is a scholar working on Molecular Biology, Genetics and Molecular Medicine. According to data from OpenAlex, Mark P. Brynildsen has authored 69 papers receiving a total of 4.3k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Molecular Biology, 38 papers in Genetics and 29 papers in Molecular Medicine. Recurrent topics in Mark P. Brynildsen's work include Bacterial Genetics and Biotechnology (38 papers), Antibiotic Resistance in Bacteria (29 papers) and Gene Regulatory Network Analysis (12 papers). Mark P. Brynildsen is often cited by papers focused on Bacterial Genetics and Biotechnology (38 papers), Antibiotic Resistance in Bacteria (29 papers) and Gene Regulatory Network Analysis (12 papers). Mark P. Brynildsen collaborates with scholars based in United States and Taiwan. Mark P. Brynildsen's co-authors include James J. Collins, Mehmet A. Orman, Kyle R. Allison, James C. Liao, Wendy W. K. Mok, Jonathan Winkler, Catherine S. Spina, Katherine Volzing, Jonathan L. Robinson and Taizo Hanai and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Mark P. Brynildsen

65 papers receiving 4.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Metabolite-enabled eradication of bacterial persisters by aminoglycosides

2011 760 citations Mark P. Brynildsen et al. profile →
Metabolic engineering of Escherichia coli for 1-butanol production

2007 613 citations Mark P. Brynildsen, James C. Liao et al. profile →
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production

2013 388 citations Mark P. Brynildsen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mark P. Brynildsen United States	26	2.7k	1.5k	1.2k	714	682	69	4.3k
Kyoung‐Hee Choi South Korea	25	2.4k 0.9×	1.2k 0.8×	741 0.6×	653 0.9×	443 0.6×	73	4.4k
Orit Gefen Israel	12	1.5k 0.6×	1.0k 0.7×	1.1k 0.8×	400 0.6×	273 0.4×	16	3.1k
Rodolfo García‐Contreras Mexico	33	2.2k 0.8×	667 0.4×	996 0.8×	622 0.9×	243 0.4×	97	3.6k
Gregory T. Robertson United States	27	2.6k 1.0×	956 0.6×	445 0.4×	672 0.9×	305 0.4×	59	5.2k
Irine Ronin Israel	12	1.3k 0.5×	1.1k 0.8×	874 0.7×	430 0.6×	203 0.3×	14	2.6k
Fernando C. Soncini Argentina	29	1.5k 0.6×	1.3k 0.9×	633 0.5×	1.3k 1.9×	233 0.3×	55	4.1k
Giordano Rampioni Italy	28	1.9k 0.7×	719 0.5×	864 0.7×	332 0.5×	346 0.5×	75	2.7k
Alessandra Polissi Italy	32	1.6k 0.6×	1.4k 0.9×	979 0.8×	535 0.7×	155 0.2×	86	3.5k
Taiji Nakae Japan	44	3.8k 1.4×	2.3k 1.6×	2.4k 1.9×	878 1.2×	477 0.7×	161	6.9k
Tung T. Hoang United States	27	3.0k 1.1×	1.6k 1.1×	1.2k 0.9×	773 1.1×	168 0.2×	45	4.3k

Countries citing papers authored by Mark P. Brynildsen

Since Specialization

Citations

This map shows the geographic impact of Mark P. Brynildsen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark P. Brynildsen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark P. Brynildsen more than expected).

Fields of papers citing papers by Mark P. Brynildsen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark P. Brynildsen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark P. Brynildsen. The network helps show where Mark P. Brynildsen may publish in the future.

Co-authorship network of co-authors of Mark P. Brynildsen

This figure shows the co-authorship network connecting the top 25 collaborators of Mark P. Brynildsen. A scholar is included among the top collaborators of Mark P. Brynildsen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark P. Brynildsen. Mark P. Brynildsen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Brynildsen, Mark P., et al.. (2025). Conservation and divergence of ciprofloxacin persister survival mechanisms between Pseudomonas aeruginosa and Escherichia coli. PLoS Genetics. 21(9). e1011840–e1011840.

Brynildsen, Mark P., et al.. (2024). Loss of Gre factors leads to phenotypic heterogeneity and cheating in Escherichia coli populations under nitric oxide stress. mBio. 15(10). e0222924–e0222924.

Brynildsen, Mark P., et al.. (2023). Amino acids can deplete ATP and impair nitric oxide detoxification by Escherichia coli. Free Radical Biology and Medicine. 205. 90–99.

Brynildsen, Mark P., et al.. (2022). Genome-wide mapping of fluoroquinolone-stabilized DNA gyrase cleavage sites displays drug specific effects that correlate with bacterial persistence. Nucleic Acids Research. 51(3). 1208–1228. 6 indexed citations

Murawski, Allison M., Katherine Rittenbach, Christina J. DeCoste, Gary Laevsky, & Mark P. Brynildsen. (2021). Counting Chromosomes in Individual Bacteria to Quantify Their Impacts on Persistence. Methods in molecular biology. 2357. 125–146. 2 indexed citations

Brynildsen, Mark P., et al.. (2021). Robustness of nitric oxide detoxification to nitrogen starvation in Escherichia coli requires RelA. Free Radical Biology and Medicine. 176. 286–297. 5 indexed citations

Brynildsen, Mark P., et al.. (2020). Quantitative Modeling Extends the Antibacterial Activity of Nitric Oxide. Frontiers in Physiology. 11. 330–330. 12 indexed citations

Brynildsen, Mark P., et al.. (2019). Transcriptional Regulation Contributes to Prioritized Detoxification of Hydrogen Peroxide over Nitric Oxide. Journal of Bacteriology. 201(14). 13 indexed citations

Riuró, Helena, et al.. (2019). Checks and Balances with Use of the Keio Collection for Phenotype Testing. Methods in molecular biology. 1927. 125–138. 5 indexed citations

10.

Robinson, Jonathan L. & Mark P. Brynildsen. (2016). Discovery and dissection of metabolic oscillations in the microaerobic nitric oxide response network of Escherichia coli. Proceedings of the National Academy of Sciences. 113(12). E1757–66. 22 indexed citations

11.

Gowers, Glen-Oliver F., Jonathan L. Robinson, & Mark P. Brynildsen. (2016). Starved Escherichia coli preserve reducing power under nitric oxide stress. Biochemical and Biophysical Research Communications. 476(1). 29–34. 6 indexed citations

12.

Brynildsen, Mark P., et al.. (2016). Development of Persister-FACSeq: a method to massively parallelize quantification of persister physiology and its heterogeneity. Scientific Reports. 6(1). 25100–25100. 33 indexed citations

13.

Brynildsen, Mark P., et al.. (2015). Persister Heterogeneity Arising from a Single Metabolic Stress. Current Biology. 25(16). 2090–2098. 108 indexed citations

14.

Brynildsen, Mark P., et al.. (2015). A Kinetic Platform to Determine the Fate of Hydrogen Peroxide in Escherichia coli. PLoS Computational Biology. 11(11). e1004562–e1004562. 23 indexed citations

15.

Orman, Mehmet A. & Mark P. Brynildsen. (2015). Inhibition of stationary phase respiration impairs persister formation in E. coli. Nature Communications. 6(1). 10756–10756. 105 indexed citations

16.

Robinson, Jonathan L., et al.. (2014). Model-driven identification of dosing regimens that maximize the antimicrobial activity of nitric oxide. Metabolic Engineering Communications. 1. 12–18. 17 indexed citations

17.

Fazen, Christopher H., et al.. (2014). The role of metabolism in bacterial persistence. Frontiers in Microbiology. 5. 70–70. 192 indexed citations

18.

Orman, Mehmet A., et al.. (2013). Metabolic Control of Persister Formation in Escherichia coli. Molecular Cell. 50(4). 475–487. 273 indexed citations

19.

Brynildsen, Mark P., Linh M. Tran, & James C. Liao. (2006). Versatility and Connectivity Efficiency of Bipartite Transcription Networks. Biophysical Journal. 91(8). 2749–2759. 6 indexed citations

20.

Suen, Jason K., et al.. (2005). Inferring yeast cell cycle regulators and interactions using transcription factor activities. BMC Genomics. 6(1). 90–90. 53 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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