Mark Hedglin

1.2k total citations
29 papers, 882 citations indexed

About

Mark Hedglin is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Mark Hedglin has authored 29 papers receiving a total of 882 indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 6 papers in Cancer Research and 5 papers in Genetics. Recurrent topics in Mark Hedglin's work include DNA Repair Mechanisms (20 papers), DNA and Nucleic Acid Chemistry (8 papers) and CRISPR and Genetic Engineering (7 papers). Mark Hedglin is often cited by papers focused on DNA Repair Mechanisms (20 papers), DNA and Nucleic Acid Chemistry (8 papers) and CRISPR and Genetic Engineering (7 papers). Mark Hedglin collaborates with scholars based in United States and Czechia. Mark Hedglin's co-authors include Stephen J. Benkovic, Patrick O’Brien, Ravindra Kumar, Stephen J. Benkovic, Brett Marshall, Eric Verdin, Scott M. Ulrich, Mahesh Aitha, Yaru Zhang and Senthil K. Perumal and has published in prestigious journals such as Nature, Chemical Reviews and Proceedings of the National Academy of Sciences.

In The Last Decade

Mark Hedglin

26 papers receiving 875 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Mark Hedglin United States 16 811 166 129 95 50 29 882
Matthew J. Schellenberg United States 19 1.2k 1.4× 212 1.3× 85 0.7× 68 0.7× 40 0.8× 34 1.2k
Kostya I. Panov United Kingdom 19 1.1k 1.4× 121 0.7× 91 0.7× 89 0.9× 44 0.9× 32 1.2k
Sivaraja Vaithiyalingam United States 14 767 0.9× 133 0.8× 170 1.3× 79 0.8× 66 1.3× 20 831
Andrey G. Baranovskiy United States 17 808 1.0× 107 0.6× 161 1.2× 100 1.1× 51 1.0× 31 924
Tracy K. Hale New Zealand 12 661 0.8× 94 0.6× 112 0.9× 80 0.8× 57 1.1× 24 848
Aaron C. Mason United States 14 887 1.1× 202 1.2× 125 1.0× 150 1.6× 81 1.6× 17 939
Jun Hyun Kim United States 16 616 0.8× 199 1.2× 60 0.5× 68 0.7× 44 0.9× 27 861
William Ramos United States 11 710 0.9× 137 0.8× 72 0.6× 139 1.5× 50 1.0× 12 761
Laura Baranello United States 19 1.4k 1.7× 238 1.4× 97 0.8× 112 1.2× 58 1.2× 30 1.5k
Vincent Brondani Switzerland 12 1.0k 1.3× 122 0.7× 196 1.5× 108 1.1× 49 1.0× 17 1.2k

Countries citing papers authored by Mark Hedglin

Since Specialization
Citations

This map shows the geographic impact of Mark Hedglin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Hedglin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Hedglin more than expected).

Fields of papers citing papers by Mark Hedglin

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Hedglin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Hedglin. The network helps show where Mark Hedglin may publish in the future.

Co-authorship network of co-authors of Mark Hedglin

This figure shows the co-authorship network connecting the top 25 collaborators of Mark Hedglin. A scholar is included among the top collaborators of Mark Hedglin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark Hedglin. Mark Hedglin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hile, Suzanne E., Matthias H. Weissensteiner, Joseph M. Dahl, et al.. (2025). Replicative DNA polymerase epsilon and delta holoenzymes show wide-ranging inhibition at G-quadruplexes in the human genome. Nucleic Acids Research. 53(8). 1 indexed citations
2.
Hedglin, Mark, et al.. (2025). Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA. Journal of Biological Chemistry. 301(4). 108342–108342.
3.
Greenberg, Marc M., et al.. (2025). A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities. Nucleic Acids Research. 53(13). 1 indexed citations
4.
Gerber, Michael H., Matthew A. Schaich, Sua Myong, et al.. (2025). Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex. Nature Communications. 17(1). 6–6.
5.
6.
Hedglin, Mark, et al.. (2024). Direct, ensemble FRET approaches to monitor transient state kinetics of human DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis. Methods in enzymology on CD-ROM/Methods in enzymology. 705. 271–309.
7.
Hedglin, Mark, et al.. (2024). PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress. Nature Communications. 15(1). 2857–2857. 12 indexed citations
8.
Eckert, Kristin A., et al.. (2024). Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels. Biochemistry. 63(8). 969–983. 1 indexed citations
9.
Chadda, Rahul, et al.. (2023). Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics. Nucleic Acids Research. 51(13). 6738–6753. 15 indexed citations
10.
Carvajal-Garcia, Juan, Dipika Gupta, David W. Wyatt, et al.. (2023). Stepwise requirements for polymerases δ and θ in theta-mediated end joining. Nature. 623(7988). 836–841. 18 indexed citations
11.
Hedglin, Mark, et al.. (2022). Tracking of progressing human DNA polymerase δ holoenzymes reveals distributions of DNA lesion bypass activities. Nucleic Acids Research. 50(17). 9893–9908. 5 indexed citations
12.
Gaubitz, Christl, et al.. (2020). Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch. Proceedings of the National Academy of Sciences. 117(38). 23571–23580. 29 indexed citations
13.
Hedglin, Mark, et al.. (2020). Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Research. 48(4). 2144–2155. 8 indexed citations
14.
Sengupta, Bhaswati, et al.. (2020). PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments. Biochemistry. 59(49). 4694–4702. 15 indexed citations
15.
Hedglin, Mark, Mahesh Aitha, Anthony M. Pedley, & Stephen J. Benkovic. (2019). Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen. Journal of Biological Chemistry. 294(13). 5157–5168. 22 indexed citations
16.
Hedglin, Mark, Mahesh Aitha, & Stephen J. Benkovic. (2017). Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA. Biochemistry. 56(27). 3415–3421. 15 indexed citations
17.
Hedglin, Mark & Stephen J. Benkovic. (2015). Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance. Annual Review of Biophysics. 44(1). 207–228. 87 indexed citations
18.
Hedglin, Mark, Yaru Zhang, & Patrick O’Brien. (2013). Isolating Contributions from Intersegmental Transfer to DNA Searching by Alkyladenine DNA Glycosylase*. Journal of Biological Chemistry. 288(34). 24550–24559. 27 indexed citations
19.
Hedglin, Mark, Ravindra Kumar, & Stephen J. Benkovic. (2013). Replication Clamps and Clamp Loaders. Cold Spring Harbor Perspectives in Biology. 5(4). a010165–a010165. 146 indexed citations
20.
Marshall, Brett, et al.. (2007). Design and evaluation of ‘Linkerless’ hydroxamic acids as selective HDAC8 inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(10). 2874–2878. 166 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Matthew J. Schellenberg Breakdown of academic impact, for papers by Kostya I. Panov Breakdown of academic impact, for papers by Sivaraja Vaithiyalingam Breakdown of academic impact, for papers by Andrey G. Baranovskiy Breakdown of academic impact, for papers by Tracy K. Hale Breakdown of academic impact, for papers by Aaron C. Mason Breakdown of academic impact, for papers by Jun Hyun Kim Breakdown of academic impact, for papers by William Ramos Breakdown of academic impact, for papers by Laura Baranello Breakdown of academic impact, for papers by Vincent Brondani
Rankless by CCL
2026