Mark E. Kleinman

7.8k total citations · 1 hit paper
31 papers, 3.3k citations indexed

About

Mark E. Kleinman is a scholar working on Molecular Biology, Ophthalmology and Immunology. According to data from OpenAlex, Mark E. Kleinman has authored 31 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 12 papers in Ophthalmology and 6 papers in Immunology. Recurrent topics in Mark E. Kleinman's work include Retinal Diseases and Treatments (12 papers), Retinal Development and Disorders (8 papers) and RNA regulation and disease (4 papers). Mark E. Kleinman is often cited by papers focused on Retinal Diseases and Treatments (12 papers), Retinal Development and Disorders (8 papers) and RNA regulation and disease (4 papers). Mark E. Kleinman collaborates with scholars based in United States, Italy and France. Mark E. Kleinman's co-authors include Geoffrey C. Gurtner, Oren M. Tepper, Robert D. Galiano, Jennifer M. Capla, Matthew J. Callaghan, Daniel J. Ceradini, Jamie P. Levine, Nicholas Bastidas, Anita R. Kulkarni and Daniel J. Ceradini and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Medicine and SHILAP Revista de lepidopterología.

In The Last Decade

Mark E. Kleinman

31 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

2004 2.1k citations Daniel J. Ceradini, Anita R. Kulkarni et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mark E. Kleinman United States	16	1.6k	733	702	685	675	31	3.3k
Aernout Luttun Belgium	40	2.1k 1.3×	748 1.0×	557 0.8×	695 1.0×	941 1.4×	91	4.4k
Jennifer M. Capla United States	9	2.3k 1.4×	898 1.2×	892 1.3×	1.0k 1.5×	812 1.2×	12	4.1k
Daniel J. Ceradini United States	22	1.3k 0.8×	748 1.0×	787 1.1×	766 1.1×	1.3k 1.9×	58	3.7k
Nicholas Bastidas United States	13	1.3k 0.8×	682 0.9×	621 0.9×	743 1.1×	725 1.1×	47	3.4k
Jean Plouët France	38	2.9k 1.8×	779 1.1×	694 1.0×	277 0.4×	355 0.5×	69	4.5k
Per Levéen Sweden	19	2.7k 1.7×	535 0.7×	608 0.9×	351 0.5×	645 1.0×	26	4.5k
Osamu Ohneda Japan	39	2.8k 1.7×	1.1k 1.5×	1.1k 1.6×	994 1.5×	500 0.7×	92	4.9k
Ann E. Canfield United Kingdom	36	1.6k 1.0×	433 0.6×	483 0.7×	704 1.0×	644 1.0×	65	3.9k
Laura E. Mead United States	21	2.9k 1.8×	655 0.9×	707 1.0×	955 1.4×	787 1.2×	28	4.5k
Errol S. Wijelath United States	21	1.8k 1.1×	519 0.7×	516 0.7×	495 0.7×	619 0.9×	37	2.9k

Countries citing papers authored by Mark E. Kleinman

Since Specialization

Citations

This map shows the geographic impact of Mark E. Kleinman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark E. Kleinman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark E. Kleinman more than expected).

Fields of papers citing papers by Mark E. Kleinman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark E. Kleinman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark E. Kleinman. The network helps show where Mark E. Kleinman may publish in the future.

Co-authorship network of co-authors of Mark E. Kleinman

This figure shows the co-authorship network connecting the top 25 collaborators of Mark E. Kleinman. A scholar is included among the top collaborators of Mark E. Kleinman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark E. Kleinman. Mark E. Kleinman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hernandez, Alvaro G., et al.. (2025). Deciphering age-related transcriptomic changes in the mouse retinal pigment epithelium. Aging. 17(3). 657–684. 3 indexed citations

Kleinman, Mark E., et al.. (2024). Unraveling Histone Loss in Aging and Senescence. Cells. 13(4). 320–320. 12 indexed citations

Zhong, Yu, Kabhilan Mohan, Jinpeng Liu, et al.. (2020). Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1866(10). 165883–165883. 23 indexed citations

Wang, Qing Jun, et al.. (2020). Imaging data on characterization of retinal autofluorescent lesions in a mouse model of juvenile neuronal ceroid lipofuscinosis (CLN3 disease). SHILAP Revista de lepidopterología. 32. 106076–106076. 3 indexed citations

Kleinman, Mark E., et al.. (2017). Safety and efficiency of CRISPR-Cas9 gene editing in the retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 58(8). 1981–1981. 1 indexed citations

Gelfand, Bradley D., Charles B. Wright, Young‐Hee Kim, et al.. (2015). Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. Cell Reports. 11(11). 1686–1693. 70 indexed citations

Kleinman, Mark E. & Jayakrishna Ambati. (2015). Complement Activation and Inhibition in Retinal Diseases. Developments in ophthalmology. 55. 46–56. 7 indexed citations

Wright, Charles B., Young‐Hee Kim, Tetsuhiro Yasuma, et al.. (2014). Enhanced Alu RNA stability due to iron-mediated DICER1 impairment causes NLRP3 inflammasome priming. Investigative Ophthalmology & Visual Science. 55(13). 2187–2187. 1 indexed citations

Kleinman, Mark E., Dingyuan Lou, Jennifer Brown, et al.. (2014). Histone Deacetylase Expression and Inhibition in Age Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 55(13). 3457–3457. 1 indexed citations

10.

Kleinman, Mark E., Dingyuan Lou, Kabhilan Mohan, et al.. (2013). Epigenetic Regulation of Eotaxin Expression in Human Retinal Pigment Epithelium. Investigative Ophthalmology & Visual Science. 54(15). 344–344. 1 indexed citations

11.

Dridi, Sami, Yoshio Hirano, Valeria Tarallo, et al.. (2012). ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences. 109(34). 13781–13786. 85 indexed citations

12.

Dridi, Sami, Hiroki Kaneko, Valeria Tarallo, et al.. (2011). Dicer Dysregulation Induces Cytotoxic Alu Rna Accumulation In Age-related Macular Degeneration. Investigative Ophthalmology & Visual Science. 52(14). 2349–2349. 1 indexed citations

13.

Kleinman, Mark E. & Jayakrishna Ambati. (2011). A Window to Innate Neuroimmunity: Toll-Like Receptor-Mediated Cell Responses in the Retina. Advances in experimental medicine and biology. 723. 3–9. 5 indexed citations

14.

Kleinman, Mark E., Judit Baffi, & Jayakrishna Ambati. (2010). The Multifactorial Nature of Retinal Vascular Disease. Ophthalmologica. 224(Suppl. 1). 16–24. 23 indexed citations

15.

Cho, Won Gil, Romulo Albuquerque, Mark E. Kleinman, et al.. (2009). Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth. Proceedings of the National Academy of Sciences. 106(17). 7137–7142. 120 indexed citations

16.

Losken, H. Wolfgang, Mark E. Kleinman, Jeffrey R. Marcus, et al.. (2006). No Evidence for Maternal–Fetal Microchimerism in Infantile Hemangioma: A Molecular Genetic Investigation. Journal of Investigative Dermatology. 126(11). 2533–2538. 27 indexed citations

17.

Kleinman, Mark E., Francine Blei, & Geoffrey C. Gurtner. (2005). Circulating Endothelial Progenitor Cells and Vascular Anomalies. Lymphatic Research and Biology. 3(4). 234–239. 18 indexed citations

18.

Ceradini, Daniel J., Anita R. Kulkarni, Matthew J. Callaghan, et al.. (2004). Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nature Medicine. 10(8). 858–864. 2120 indexed citations breakdown →

19.

Kleinman, Mark E., Oren M. Tepper, Jennifer M. Capla, et al.. (2003). Increased Circulating AC133 ₊ CD34 ₊ Endothelial Progenitor Cells in Children with Hemangioma. Lymphatic Research and Biology. 1(4). 301–307. 46 indexed citations

20.

Tepper, Oren M., Robert D. Galiano, Jennifer M. Capla, et al.. (2003). Selective Recruitment of Endothelial Progenitor Cells to Ischemic Tissues with Increased Neovascularization. Plastic & Reconstructive Surgery. 113(1). 284–293. 67 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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