Mark D. Distefano

7.5k citations

169 papers · 6.0k indexed · 1 hit paper · h-index 42

Organic Chemistry top 1%
- Click Chemistry and Applications 67
Molecular Biology top 1%
- Chemical Synthesis and Analysis 41
- Ubiquitin and proteasome pathways 27
- Plant biochemistry and biosynthesis 20
Cell Biology top 1%
- Biotin and Related Studies 23
Radiology, Nuclear Medicine and Imaging top 2%
- Monoclonal and Polyclonal Antibodies Research 27
Oncology top 5%
- Peptidase Inhibition and Analysis 16
Materials Chemistry
- Enzyme Structure and Function 12

Co-authors: Jonathan K. Dozier Mohammad Rashidian Charuta C. Palsuledesai Kiall F. Suazo Melissa J. Moore Keun‐Young Park Christopher T. Walsh Dongfeng Qi
Cited by: Organic Chemistry Molecular Biology Cell Biology
Journals: Journal of the American Chemical Society (15 papers)Bioconjugate Chemistry (11 papers)Bioorganic & Medicinal Chemistry Letters (8 papers)
Partner nations: United States Switzerland Canada

In The Last Decade

Mark D. Distefano

168 papers receiving 5.9k citations

Hit Papers

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Peers

Countries citing papers authored by Mark D. Distefano

Since Specialization

Citations

This map shows the geographic impact of Mark D. Distefano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark D. Distefano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark D. Distefano more than expected).

Fields of papers citing papers by Mark D. Distefano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark D. Distefano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark D. Distefano. The network helps show where Mark D. Distefano may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Mark D. Distefano, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark D. Distefano Line = papers co-authored together Mark D. Distefano links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Engineering protein prenylation: an emerging tool for selective protein modification Biochemical Society Transactions ·유희준,Takashi Unno,Carston R. Wagner,Mark D. Distefano	2025	1
2	The utility of Streptococcus mutans undecaprenol kinase for the chemoenzymatic synthesis of diverse non-natural isoprenoids Bioorganic Chemistry ·Vikas Kumar,成田久仁夫,W. Osiander,Г.М. Адырбекова,Anna Bertiger,Riki Das,Т.Т. Муханова,Mark D. Distefano,Shanteri Singh	2024	2
3	Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene–Tetrazine Click Chemistry Bioconjugate Chemistry ·Mud Yanto,유희준,Kiall F. Suazo,Yiao Wang,DAVID HONGKHAM,M. Chapuis,伊藤亜聖,Jonas V. Schaefer,susan feizi,Andreas Plückthun,Ling Li,Mark D. Distefano	2024	3
4	Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors Bioorganic Chemistry ·Kiall F. Suazo,Vartika Mishra,Т.Т. Муханова,Mud Yanto,伊藤亜聖,D. N. Waters,Linda Ottoboni,Derick Mateus de Jesus Oliveira,Stefania Corti,Francesco Lotti,Serge Przedborski,Mark D. Distefano	2024	1
5	Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death Bioconjugate Chemistry ·Yiao Wang,Jens Hollinderbäumer,Javier CHAPARRO-ACOSTA,Mark D. Distefano,Carston R. Wagner	2024	3
6	Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities Nature Communications ·R Hukmi,Mud Yanto,Maycoll Stiven Romero Güiza,Atys Quadros Da Silva,J Cárdenas-Poblador,Peter G. Bruce,Jelena Milosevic,Chen Xuzhuo,Abirami Kugadas,Xiaoxiao Lu,Jennifer Geddes‐McAlister,Raina N. Fichorova,David B. Sykes,Mark D. Distefano,Mihaela Gadjeva	2023	9
7	GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS Journal of Biological Chemistry ·Bigman Galya,Ellen Lorimer,L. Lindemann,吕善广,Tom Mannewitz,Kiall F. Suazo,Mud Yanto,Mark D. Distefano,Jeremy W. Prokop,Carol L. Williams	2023	9
8	Manipulating Cell Fates with Protein Conjugates Bioconjugate Chemistry ·Yiao Wang,Carston R. Wagner,Mark D. Distefano	2022	5
9	Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation ACS Chemical Biology ·Johannes Morstein,A. Hollnagel,Stalnaya Maya Ivanovna,Fei Yang,Rowse Hr,James L. Hougland,Christine A. Hrycyna,Dirk Trauner,Mark D. Distefano	2022	9
10	Engineering Biomimetic Trogocytosis with Farnesylated Chemically Self-Assembled Nanorings Biomacromolecules ·Yiao Wang,Javier CHAPARRO-ACOSTA,Jens Hollinderbäumer,Takashi Unno,Ryou Mishima,Mark D. Distefano,Carston R. Wagner	2022	6
11	Directed cell migration towards softer environmentsbreakdown → Nature Materials ·Aleksi Isomursu,Keun‐Young Park,Jay Hou,Bo Cheng,Mathilde Mathieu,Ghaidan A. Shamsan,Dana Angelina Schaar,Noa,M. Mohsen Mahmoodi,Tian Jian Lu,Guy M. Genin,Feng Xu,Min Lin,Mark D. Distefano,Johanna Ivaska,David J. Odde	2022	151
12	Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T Cell-Mediated Antitumor Responses and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression Journal of Medicinal Chemistry ·Jens Hollinderbäumer,جميلة نصر,James E. Record,Yiao Wang,Jill M. Siegfried,Mark D. Distefano,Carston R. Wagner	2020	8
13	Engineering reversible cell–cell interactions using enzymatically lipidated chemically self-assembled nanorings Chemical Science ·Yiao Wang,Jens Hollinderbäumer,Clifford M. Csizmar,Rowse Hr,James L. Hougland,Mark D. Distefano,Carston R. Wagner	2020	17
14	Site-Selective Enzymatic Labeling of Designed Ankyrin Repeat Proteins Using Protein Farnesyltransferase Methods in molecular biology ·Yi Zhang,Mud Yanto,Jonas V. Schaefer,Andreas Plückthun,Mark D. Distefano	2019	6
15	A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins Molecular BioSystems ·Charuta C. Palsuledesai,Joshua D. Ochocki,Todd W. Markowski,Mark D. Distefano	2014	28
16	Chemoenzymatic Reversible Immobilization and Labeling of Proteins without Prior Purification Journal of the American Chemical Society ·Mohammad Rashidian,Andréia C. Calles,Rachel Pricer,Mark D. Distefano	2012	82
17	Covalent protein–oligonucleotide conjugates by copper-free click reaction Bioorganic & Medicinal Chemistry ·张冠英,傅永伦,Daniel G. Mullen,Michael A. Hast,L.S. Beese,Mark D. Distefano,T. Andrew Taton	2012	39
18	Photochemical Modulation of Ras‐Mediated Signal Transduction Using Caged Farnesyltransferase Inhibitors: Activation by One‐ and Two‐Photon Excitation ChemBioChem ·Oswaldo García Crespo,Miguel Inacio,Joshua D. Ochocki,Janel K. Warmka,Timothy M. Dore,David A. Blank,Elizabeth V. Wattenberg,Mark D. Distefano	2012	19
19	Selective Labeling of Proteins by Using Protein Farnesyltransferase ChemBioChem ·Benjamin P. Duckworth,Zhiyuan Zhang,Joffre Fernando Trujillo Castillo,Mark D. Distefano	2006	98
20	Evidence for the participation of Cys558 and Cys559 at the active site of mercuric reductase Biochemistry ·Susan M. Miller,Melissa J. Moore,Vincent Massey,Charles H. Williams,Mark D. Distefano,David P. Ballou,Christopher T. Walsh	1989	69

About Mark D. Distefano

Mark D. Distefano is a scholar working on Organic Chemistry, Cell Biology and Molecular Biology, having authored 169 papers that have together received 6.0k indexed citations. Recurring topics across this work include Click Chemistry and Applications (67 papers), Chemical Synthesis and Analysis (41 papers), Ubiquitin and proteasome pathways (27 papers), Monoclonal and Polyclonal Antibodies Research (27 papers), Biotin and Related Studies (23 papers), Plant biochemistry and biosynthesis (20 papers), Peptidase Inhibition and Analysis (16 papers) and Enzyme Structure and Function (12 papers). The work is most often cited by research in Organic Chemistry (1.9k citations), Molecular Biology (4.0k citations) and Cell Biology (810 citations). Mark D. Distefano has collaborated with scholars based in United States, Switzerland and Canada. Frequent co-authors include Jonathan K. Dozier, Mohammad Rashidian, Charuta C. Palsuledesai, Kiall F. Suazo, Melissa J. Moore, Keun‐Young Park, Christopher T. Walsh, Dongfeng Qi, Dietmar Häring and Joshua D. Ochocki. Their work appears in journals such as Journal of the American Chemical Society, Bioconjugate Chemistry, Bioorganic & Medicinal Chemistry Letters, Biochemistry and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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