M. Michael Appleman

3.0k total citations · 1 hit paper
26 papers, 2.6k citations indexed

About

M. Michael Appleman is a scholar working on Molecular Biology, Organic Chemistry and Physiology. According to data from OpenAlex, M. Michael Appleman has authored 26 papers receiving a total of 2.6k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Molecular Biology, 7 papers in Organic Chemistry and 7 papers in Physiology. Recurrent topics in M. Michael Appleman's work include Phosphodiesterase function and regulation (11 papers), Enzyme function and inhibition (7 papers) and Adenosine and Purinergic Signaling (7 papers). M. Michael Appleman is often cited by papers focused on Phosphodiesterase function and regulation (11 papers), Enzyme function and inhibition (7 papers) and Adenosine and Purinergic Signaling (7 papers). M. Michael Appleman collaborates with scholars based in United States, Argentina and China. M. Michael Appleman's co-authors include W. J. Thompson, Gary Brooker, Lyell J. Thomas, Wesley L. Terasaki, Tom R. Russell, Héctor N. Torres, Edmond H. Fischer, Edwin G. Krebs, Robert G. Kemp and Lutz Birnbaumer and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Biochemistry.

In The Last Decade

M. Michael Appleman

25 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Multiple cyclic nucleotide phosphodiesterase activities from rat brain

1971 969 citations M. Michael Appleman, W. J. Thompson Biochemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
M. Michael Appleman United States	18	1.9k	473	421	394	332	26	2.6k
Roger A. Johnson United States	25	1.9k 1.0×	307 0.6×	216 0.5×	372 0.9×	117 0.4×	76	2.6k
Gordon L. Bundy United States	24	1.2k 0.6×	400 0.8×	615 1.5×	126 0.3×	620 1.9×	66	2.9k
N D Goldberg United States	25	1.7k 0.9×	560 1.2×	155 0.4×	212 0.5×	158 0.5×	39	2.7k
John E. Bleasdale United States	25	1.8k 0.9×	641 1.4×	126 0.3×	307 0.8×	184 0.6×	56	3.7k
B. V. L. POTTER United Kingdom	35	2.4k 1.2×	173 0.4×	664 1.6×	275 0.7×	172 0.5×	97	3.6k
Paul M. Epstein United States	26	1.5k 0.8×	250 0.5×	226 0.5×	136 0.3×	320 1.0×	64	2.0k
Gary L. Petzold United States	25	2.0k 1.1×	227 0.5×	361 0.9×	105 0.3×	199 0.6×	35	3.3k
J. G. Hardman United States	17	969 0.5×	377 0.8×	115 0.3×	178 0.5×	99 0.3×	24	1.4k
F.A. Fitzpatrick United States	22	1.2k 0.6×	289 0.6×	144 0.3×	87 0.2×	513 1.5×	34	2.4k
James D. Bergstrom United States	27	3.1k 1.6×	599 1.3×	461 1.1×	92 0.2×	325 1.0×	61	4.5k

Countries citing papers authored by M. Michael Appleman

Since Specialization

Citations

This map shows the geographic impact of M. Michael Appleman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by M. Michael Appleman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites M. Michael Appleman more than expected).

Fields of papers citing papers by M. Michael Appleman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by M. Michael Appleman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by M. Michael Appleman. The network helps show where M. Michael Appleman may publish in the future.

Co-authorship network of co-authors of M. Michael Appleman

This figure shows the co-authorship network connecting the top 25 collaborators of M. Michael Appleman. A scholar is included among the top collaborators of M. Michael Appleman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with M. Michael Appleman. M. Michael Appleman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chen, Xiaodi, M. Michael Appleman, Tuong Vi Tran, et al.. (2025). Novel peptidomimetic compounds attenuate hypoxic-ischemic brain injury in neonatal rats. Experimental Neurology. 386. 115151–115151.

Yang, Xin, Mengia S. Rioult-Pedotti, Stephen Tang, et al.. (2023). A PSD-95 peptidomimetic mitigates neurological deficits in a mouse model of Angelman syndrome. Progress in Neurobiology. 230. 102513–102513. 12 indexed citations

Chung, Fu‐Zon, et al.. (1986). Insulin stimulation of cyclic AMP phosphodiesterase is independent from the G-protein pathways involved in adenylate cyclase regulation.. PubMed. 11(5). 345–54. 6 indexed citations

Chung, Fu‐Zon, et al.. (1985). Extensive but reversible depletion of ATP via adenylate cyclase in rat adipocytes.. Proceedings of the National Academy of Sciences. 82(6). 1614–1617. 13 indexed citations

Whitson, Robert H. & M. Michael Appleman. (1982). Purification, characterization and production of rabbit antibodies to rat liver particulate, high-affinity, cyclic AMP phosphodiesterase. Biochimica et Biophysica Acta (BBA) - General Subjects. 714(2). 279–291. 17 indexed citations

Ariano, Marjorie A., Larry L. Butcher, & M. Michael Appleman. (1980). Cyclic nucleotides in the rat caudate-putamen complex: Histochemical characterization and effects of deafferentation and kainic acid infusion. Neuroscience. 5(7). 1269–1276. 12 indexed citations

Takemoto, D.J., S. A. Kaplan, & M. Michael Appleman. (1979). Cyclic guanosine 3′,5′-monophosphate and phosphodiesterase activity in mitogen-stimulated human lymphocytes. Biochemical and Biophysical Research Communications. 90(2). 491–497. 16 indexed citations

Ariano, Marjorie A. & M. Michael Appleman. (1979). Biochemical characterization of postsynaptically localized cyclic nucleotide phosphodiesterase. Brain Research. 177(2). 301–309. 27 indexed citations

Sherwìn, Russell P., et al.. (1976). Cyclic nucleotide phosphodiesterases in neoplastic and nonneoplastic human mammary tissues.. PubMed. 36(1). 60–6. 67 indexed citations

10.

Terasaki, Wesley L. & M. Michael Appleman. (1975). The role of cyclic GMP in the regulation of cyclic AMP hydrolysis. Metabolism. 24(3). 311–319. 66 indexed citations

11.

Russell, Tom R., W. J. Thompson, F. W. Schneider, & M. Michael Appleman. (1972). 3′:5′-Cyclic Adenosine Monophosphate Phosphodiesterase: Negative Cooperativity. Proceedings of the National Academy of Sciences. 69(7). 1791–1795. 53 indexed citations

12.

Thompson, W. J. & M. Michael Appleman. (1971). Characterization of Cyclic Nucleotide Phosphodiesterases of Rat Tissues. Journal of Biological Chemistry. 246(10). 3145–3150. 247 indexed citations

13.

Appleman, M. Michael & W. J. Thompson. (1971). Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry. 10(2). 311–316. 969 indexed citations breakdown →

14.

Brooker, Gary & M. Michael Appleman. (1968). Theoretical basis for the measurement of compounds by enzymic radioisotopic displacement. Biochemistry. 7(12). 4182–4184. 17 indexed citations

15.

Brooker, Gary, Lyell J. Thomas, & M. Michael Appleman. (1968). Assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymic radioisotopic displacement. Biochemistry. 7(12). 4177–4181. 324 indexed citations

16.

Appleman, M. Michael & Robert G. Kemp. (1966). Puromycin: A potent metabolic effect independent of protein synthesis. Biochemical and Biophysical Research Communications. 24(4). 564–568. 84 indexed citations

17.

Appleman, M. Michael, Lutz Birnbaumer, & Héctor N. Torres. (1966). Factors affecting the activity of muscle glycogen synthetase. Archives of Biochemistry and Biophysics. 116(1). 39–43. 106 indexed citations

18.

Belocopitow, Enrique, M. Michael Appleman, & Héctor N. Torres. (1965). Factors Affecting the Activity of Muscle Glycogen Synthetase. Journal of Biological Chemistry. 240(9). 3473–3478. 37 indexed citations

19.

Appleman, M. Michael, Enrique Belocopitow, & Héctor N. Torres. (1964). Factors affecting the activity of muscle glycogen synthetase. Biochemical and Biophysical Research Communications. 14(6). 550–554. 32 indexed citations

20.

Appleman, M. Michael, Adel A. Yunis, Edwin G. Krebs, & Edmond H. Fischer. (1963). Comparative Studies on Glycogen Phosphorylase. Journal of Biological Chemistry. 238(4). 1358–1361. 63 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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