Luca Settimo

1.3k total citations
22 papers, 772 citations indexed

About

Luca Settimo is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Organic Chemistry. According to data from OpenAlex, Luca Settimo has authored 22 papers receiving a total of 772 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 7 papers in Cellular and Molecular Neuroscience and 4 papers in Organic Chemistry. Recurrent topics in Luca Settimo's work include Neuroscience and Neuropharmacology Research (7 papers), Receptor Mechanisms and Signaling (5 papers) and Trypanosoma species research and implications (4 papers). Luca Settimo is often cited by papers focused on Neuroscience and Neuropharmacology Research (7 papers), Receptor Mechanisms and Signaling (5 papers) and Trypanosoma species research and implications (4 papers). Luca Settimo collaborates with scholars based in United States, Finland and United Kingdom. Luca Settimo's co-authors include Ronald M. A. Knegtel, Harry P. de Koning, Jane C. Munday, Alessandra Rampazzo, Andrea Nava, Barbara Bauce, Olli T. Pentikäinen, Mark S. Johnson, Gianfranco Frigo and Giorgia Beffagna and has published in prestigious journals such as Journal of Biological Chemistry, Biochemistry and Journal of Medicinal Chemistry.

In The Last Decade

Luca Settimo

22 papers receiving 752 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Luca Settimo United States 14 273 237 120 115 113 22 772
Ian T. Crosby Australia 17 348 1.3× 13 0.1× 215 1.8× 50 0.4× 23 0.2× 47 889
Giuseppe Parlato Italy 17 418 1.5× 31 0.1× 71 0.6× 30 0.3× 34 0.3× 32 838
Lúcia Pereira-da-Silva Brazil 13 385 1.4× 40 0.2× 49 0.4× 41 0.4× 30 0.3× 23 793
Michael Kirberger United States 14 411 1.5× 27 0.1× 14 0.1× 7 0.1× 29 0.3× 22 746
Alessandro Assandri Austria 15 145 0.5× 14 0.1× 83 0.7× 8 0.1× 57 0.5× 68 649
Mengmeng Wang China 15 275 1.0× 24 0.1× 26 0.2× 7 0.1× 31 0.3× 37 566
Hermann AM Mucke United States 15 263 1.0× 41 0.2× 86 0.7× 2 0.0× 29 0.3× 112 730
G.F. Ruda United Kingdom 15 513 1.9× 55 0.2× 131 1.1× 71 0.6× 20 719
Christian Studenik Austria 14 264 1.0× 144 0.6× 115 1.0× 73 0.6× 53 654
Silvia Fallarini Italy 20 412 1.5× 84 0.4× 217 1.8× 80 0.7× 50 1.0k

Countries citing papers authored by Luca Settimo

Since Specialization
Citations

This map shows the geographic impact of Luca Settimo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luca Settimo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luca Settimo more than expected).

Fields of papers citing papers by Luca Settimo

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luca Settimo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luca Settimo. The network helps show where Luca Settimo may publish in the future.

Co-authorship network of co-authors of Luca Settimo

This figure shows the co-authorship network connecting the top 25 collaborators of Luca Settimo. A scholar is included among the top collaborators of Luca Settimo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luca Settimo. Luca Settimo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
2.
Collier, Philip N., Heather Twin, Ronald M. A. Knegtel, et al.. (2019). Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis. ACS Medicinal Chemistry Letters. 10(8). 1134–1139. 9 indexed citations
3.
Settimo, Luca & David Taylor. (2018). Evaluating the dose-dependent mechanism of action of trazodone by estimation of occupancies for different brain neurotransmitter targets. Journal of Psychopharmacology. 32(1). 96–104. 24 indexed citations
4.
Munday, Jane C., Luca Settimo, & Harry P. de Koning. (2015). Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei. Frontiers in Pharmacology. 6. 32–32. 62 indexed citations
5.
Munday, Jane C., Daniel N. A. Tagoe, Anthonius A. Eze, et al.. (2015). Functional analysis of drug resistance‐associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein. Molecular Microbiology. 96(4). 887–900. 44 indexed citations
6.
Amata, Emanuele, Nicholas D. Bland, Charles Tapley Hoyt, et al.. (2014). Repurposing human PDE4 inhibitors for neglected tropical diseases: Design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 24(17). 4084–4089. 22 indexed citations
7.
Ochiana, Stefan O., Nicholas D. Bland, Luca Settimo, R. Keith Campbell, & Michael P. Pollastri. (2014). Repurposing Human PDE4 Inhibitors for Neglected Tropical Diseases. Evaluation of Analogs of the Human PDE4 Inhibitor GSK‐256066 as Inhibitors of PDEB1 of Trypanosoma brucei. Chemical Biology & Drug Design. 85(5). 549–564. 10 indexed citations
8.
Jimenez, Juan‐Miguel, Dean Boyall, Philip N. Collier, et al.. (2013). Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry. 56(5). 1799–1810. 34 indexed citations
9.
Settimo, Luca, et al.. (2013). Comparison of the Accuracy of Experimental and Predicted pKa Values of Basic and Acidic Compounds. Pharmaceutical Research. 31(4). 1082–1095. 140 indexed citations
10.
Jimenez, Juan‐Miguel, Christopher J. Davis, Dean Boyall, et al.. (2012). Structure-based optimization of aminopyridines as PKCθ inhibitors. Bioorganic & Medicinal Chemistry Letters. 22(14). 4645–4649. 10 indexed citations
11.
Sanders, James M., Olli T. Pentikäinen, Luca Settimo, et al.. (2006). Determination of Binding Site Residues Responsible for the Subunit Selectivity of Novel Marine-Derived Compounds on Kainate Receptors. Molecular Pharmacology. 69(6). 1849–1860. 24 indexed citations
12.
Pentikäinen, Ulla, Luca Settimo, Mark S. Johnson, & Olli T. Pentikäinen. (2006). Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding. Organic & Biomolecular Chemistry. 4(6). 1058–1058. 16 indexed citations
13.
Settimo, Luca, Serena Donnini, André H. Juffer, Robert W. Woody, & Oriano Marin. (2006). Conformational changes upon calcium binding and phosphorylation in a synthetic fragment of calmodulin. Biopolymers. 88(3). 373–385. 17 indexed citations
14.
Sanders, James M., Koichi Ito, Luca Settimo, et al.. (2005). Divergent Pharmacological Activity of Novel Marine-Derived Excitatory Amino Acids on Glutamate Receptors. Journal of Pharmacology and Experimental Therapeutics. 314(3). 1068–1078. 48 indexed citations
15.
Bauce, Barbara, Cristina Basso, Alessandra Rampazzo, et al.. (2005). Clinical profile of four families with arrhythmogenic right ventricular cardiomyopathy caused by dominant desmoplakin mutations. European Heart Journal. 26(16). 1666–1675. 206 indexed citations
16.
Bagattin, Alessia, Barbara Bauce, Wim Wuyts, et al.. (2004). Denaturing HPLC-Based Approach for Detecting RYR2 Mutations Involved in Malignant Arrhythmias. Clinical Chemistry. 50(7). 1148–1155. 33 indexed citations
17.
Pentikäinen, Olli T., Luca Settimo, Kari Keinänen, & Mark S. Johnson. (2003). Selective agonist binding of (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and 2S-(2α,3β,4β)-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (kainate) receptors: a molecular modeling study. Biochemical Pharmacology. 66(12). 2413–2425. 17 indexed citations
18.
Pentikäinen, Olli T., et al.. (2003). Model structures of the N-methyl-d-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands. Journal of Structural Biology. 145(3). 205–215. 9 indexed citations
19.
Lampinen, Milla, Luca Settimo, Olli T. Pentikäinen, et al.. (2002). Discrimination between Agonists and Antagonists by the α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid-selective Glutamate Receptor. Journal of Biological Chemistry. 277(44). 41940–41947. 9 indexed citations
20.
Jouppila, Annukka, Olli T. Pentikäinen, Luca Settimo, et al.. (2002). Determinants of antagonist binding at the α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor subunit, GluR‐D. European Journal of Biochemistry. 269(24). 6261–6270. 6 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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