Lotte Brehm

1.6k total citations
74 papers, 1.2k citations indexed

About

Lotte Brehm is a scholar working on Molecular Biology, Organic Chemistry and Cellular and Molecular Neuroscience. According to data from OpenAlex, Lotte Brehm has authored 74 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Molecular Biology, 36 papers in Organic Chemistry and 26 papers in Cellular and Molecular Neuroscience. Recurrent topics in Lotte Brehm's work include Neuroscience and Neuropharmacology Research (25 papers), Chemical Synthesis and Analysis (20 papers) and Synthesis and Reactions of Organic Compounds (12 papers). Lotte Brehm is often cited by papers focused on Neuroscience and Neuropharmacology Research (25 papers), Chemical Synthesis and Analysis (20 papers) and Synthesis and Reactions of Organic Compounds (12 papers). Lotte Brehm collaborates with scholars based in Denmark, United States and Switzerland. Lotte Brehm's co-authors include Povl Krogsgaard‐Larsen, Wolfgang Nimmich, S. Brøgger Christensen, Bjarke Ebert, Ulf Madsen, Ragnhild Seip, Hans M. Seip, Birgitte Nielsen, Tommy N. Johansen and Hans Bräuner‐Osborne and has published in prestigious journals such as Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and European Journal of Pharmacology.

In The Last Decade

Lotte Brehm

72 papers receiving 1.1k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lotte Brehm Denmark	21	602	522	499	281	104	74	1.2k
Mark Froimowitz United States	16	644 1.1×	462 0.9×	296 0.6×	178 0.6×	27 0.3×	54	1.2k
Hiroshi Watanabe Japan	23	763 1.3×	523 1.0×	343 0.7×	163 0.6×	102 1.0×	91	1.7k
B. L. CHENARD United States	20	591 1.0×	516 1.0×	957 1.9×	107 0.4×	112 1.1×	30	1.6k
Pier G. De Benedetti Italy	26	2.0k 3.3×	1.1k 2.1×	488 1.0×	254 0.9×	48 0.5×	107	2.7k
Graham J. Durant United States	18	478 0.8×	156 0.3×	443 0.9×	83 0.3×	50 0.5×	32	960
Henry G. Mautner United States	24	641 1.1×	258 0.5×	523 1.0×	155 0.6×	69 0.7×	94	1.6k
James P. Wepsiec United States	11	339 0.6×	206 0.4×	691 1.4×	182 0.6×	88 0.8×	18	972
Reinhard Sarges United States	20	905 1.5×	176 0.3×	854 1.7×	169 0.6×	118 1.1×	42	1.9k
K. W. Bentley United States	18	456 0.8×	230 0.4×	654 1.3×	785 2.8×	71 0.7×	79	1.7k
Eileen M. Seward United States	24	715 1.2×	443 0.8×	935 1.9×	612 2.2×	147 1.4×	37	2.1k

Countries citing papers authored by Lotte Brehm

Since Specialization

Citations

This map shows the geographic impact of Lotte Brehm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lotte Brehm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lotte Brehm more than expected).

Fields of papers citing papers by Lotte Brehm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lotte Brehm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lotte Brehm. The network helps show where Lotte Brehm may publish in the future.

Co-authorship network of co-authors of Lotte Brehm

This figure shows the co-authorship network connecting the top 25 collaborators of Lotte Brehm. A scholar is included among the top collaborators of Lotte Brehm based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lotte Brehm. Lotte Brehm is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Clausen, Rasmus P., Peter Naur, Anders S. Kristensen, et al.. (2009). The Glutamate Receptor GluR5 Agonist (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic Acid and the 8-Methyl Analogue: Synthesis, Molecular Pharmacology, and Biostructural Characterization†PDB ID: 2WKY.. Journal of Medicinal Chemistry. 52(15). 4911–4922. 20 indexed citations

Wellendorph, Petrine, Jeremy R. Greenwood, Birgitte Nielsen, et al.. (2005). Novel Cyclic γ-Hydroxybutyrate (GHB) Analogs with High Affinity and Stereoselectivity of Binding to GHB Sites in Rat Brain. Journal of Pharmacology and Experimental Therapeutics. 315(1). 346–351. 42 indexed citations

Vogensen, Stine B., Jeremy R. Greenwood, Lotte Brehm, et al.. (2004). A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors. Organic & Biomolecular Chemistry. 2(2). 206–206. 14 indexed citations

Brehm, Lotte, Jeremy R. Greenwood, Frank A. Sløk, et al.. (2004). Synthesis, theoretical and structural analyses, and enantiopharmacology of 3‐carboxy homologs of AMPA. Chirality. 16(7). 452–466. 5 indexed citations

Jensen, Anders A., Bente Frølund, Karla Frydenvang, et al.. (2004). Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors. European Journal of Pharmacology. 497(2). 125–137. 9 indexed citations

Egebjerg, Jan, et al.. (1999). Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. Chirality. 11(10). 752–759. 23 indexed citations

Skjærbæk, Niels, Lotte Brehm, Tommy N. Johansen, et al.. (1998). Aryl and cycloalkyl analogues of AMPA: synthetic, pharmacological and stereochemical aspects. Bioorganic & Medicinal Chemistry. 6(1). 119–131. 8 indexed citations

Brehm, Lotte, Bjarke Ebert, Uffe Kristiansen, et al.. (1997). Structure and pharmacology of 4,5,6,7-tetrahydroisothiazolo[5,4-c]pyridin-3-ol (Thio-THIP), an agonist/antagonist at GABAA receptors. European Journal of Medicinal Chemistry. 32(4). 357–363. 13 indexed citations

Frølund, Bente, et al.. (1995). Partial GABAA Receptor Agonists. Synthesis and in Vitro Pharmacology of a Series of Nonannulated Analogs of 4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol. Journal of Medicinal Chemistry. 38(17). 3287–3296. 57 indexed citations

10.

Ebert, Bjarke, Lotte Brehm, Jan J. Hansen, et al.. (1994). Resolution, Absolute Stereochemistry, and Pharmacology of the S-(+)- and R-(-)-Isomers of the Apparent Partial AMPA Receptor Agonist (R,S)-2-Amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic Acid [(R,S)-APPA]. Journal of Medicinal Chemistry. 37(7). 878–884. 50 indexed citations

11.

Christensen, Inge Thøger, Bjarke Ebert, Ulf Madsen, et al.. (1992). Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid. Journal of Medicinal Chemistry. 35(19). 3512–3519. 28 indexed citations

12.

Brehm, Lotte, et al.. (1992). Isoxazol-5(4H)-ones. X-Ray crystal structures of a 4-hydroxyisoxazol-5(4H)-one and a [4,4′-biisoxazole]-5(4H),5′(4′H)-dione formed by oxygen oxidation of 3-tert-butyl-4-methylisoxazol-5(4H)-one. Journal of the Chemical Society Perkin Transactions 1. 2059–2063. 1 indexed citations

13.

Nielsen, Lone, Lotte Brehm, & Povl Krogsgaard‐Larsen. (1990). GABA agonists and uptake inhibitors. Synthesis, absolute stereochemistry, and enantioselectivity of (R)-(-)- and (S)-(+)-homo-.beta.-proline. Journal of Medicinal Chemistry. 33(1). 71–77. 56 indexed citations

14.

Madsen, Ulf, et al.. (1990). Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors. Journal of Medicinal Chemistry. 33(1). 374–380. 12 indexed citations

15.

Hansen, Jan J., et al.. (1989). Excitatory amino acid agonists. Enzymic resolution, x-ray structure, and enantioselective activities of (R)- and (S)-bromohomoibotenic acid. Journal of Medicinal Chemistry. 32(10). 2254–2260. 31 indexed citations

16.

Madsen, Ulf, Kjeld Schaumburg, Lotte Brehm, D.R. Curtis, & Povl Krogsgaard‐Larsen. (1986). ChemInform Abstract: Ibotenic Acid Analogues. Synthesis and Biological Testing of Two Bicyclic 3‐Isoxazolol Amino Acids.. Chemischer Informationsdienst. 17(26). 92–7. 6 indexed citations

17.

Christophersen, Carsten, et al.. (1985). Analogues of the Histamine Liberating Dihydroxysesquiterpene Lactone Thapsigargin. Synthesis, X-Ray Analysis and Chemistry.. Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry. 39b. 375–390. 3 indexed citations

18.

Brehm, Lotte. (1982). 2-Methyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-3-ol monohydrate, a structural analogue of THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol). Acta Crystallographica Section B. 38(10). 2741–2744. 2 indexed citations

19.

Jerslev, Bodil, et al.. (1977). The Crystal Structure and the Conformation of 1,3,5-Triacetoxyhexahydro-1,3,5-triazine.. Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry. 31b. 875–882. 6 indexed citations

20.

Frøyen, Paul, R. F. Hudson, S. Brøgger Christensen, Lotte Brehm, & Wolfgang Nimmich. (1973). Nucleophilic Reactivity of Some Nitrogen Heterocycles.. Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry. 27. 4001–4006. 2 indexed citations

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