Leonie Unterholzner

5.6k total citations · 3 hit papers
19 papers, 4.4k citations indexed

About

Leonie Unterholzner is a scholar working on Immunology, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Leonie Unterholzner has authored 19 papers receiving a total of 4.4k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Immunology, 9 papers in Molecular Biology and 6 papers in Infectious Diseases. Recurrent topics in Leonie Unterholzner's work include interferon and immune responses (14 papers), Cytokine Signaling Pathways and Interactions (6 papers) and Viral Infections and Vectors (5 papers). Leonie Unterholzner is often cited by papers focused on interferon and immune responses (14 papers), Cytokine Signaling Pathways and Interactions (6 papers) and Viral Infections and Vectors (5 papers). Leonie Unterholzner collaborates with scholars based in United Kingdom, Ireland and United States. Leonie Unterholzner's co-authors include Andrew Bowie, Elisa Izaurralde, Katherine A. Fitzgerald, Tengchuan Jin, Tsan Sam Xiao, Eicke Latz, Marcin Baran, Søren R. Paludan, Kristy Horan and Søren B. Jensen and has published in prestigious journals such as Nucleic Acids Research, Nature Communications and Immunity.

In The Last Decade

Leonie Unterholzner

19 papers receiving 4.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IFI16 is an innate immune sensor for intracellular DNA

2010 1.3k citations Leonie Unterholzner, Sinéad E. Keating et al. Nature Immunology profile →
Viral evasion and subversion of pattern-recognition receptor signalling

2008 585 citations Andrew Bowie, Leonie Unterholzner Nature reviews. Immunology profile →
Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

2018 470 citations Gillian Dunphy, Sinéad Flannery et al. Molecular Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Leonie Unterholzner United Kingdom	16	3.0k	2.3k	925	774	467	19	4.4k
Kristy Horan Australia	24	2.4k 0.8×	1.8k 0.8×	1.0k 1.1×	728 0.9×	421 0.9×	44	3.9k
Krzysztof Brzózka Poland	12	2.2k 0.7×	1.3k 0.5×	865 0.9×	807 1.0×	367 0.8×	44	3.4k
Søren B. Jensen Denmark	13	2.6k 0.9×	1.3k 0.6×	811 0.9×	800 1.0×	299 0.6×	13	3.2k
Hendrik Poeck Germany	26	4.3k 1.4×	2.4k 1.1×	958 1.0×	813 1.1×	680 1.5×	72	5.9k
Choon Ping Tan United Kingdom	13	2.2k 0.7×	1.2k 0.5×	893 1.0×	620 0.8×	267 0.6×	14	3.1k
Mika Kikuchi Japan	8	3.9k 1.3×	1.6k 0.7×	959 1.0×	792 1.0×	597 1.3×	11	4.7k
Daniel B. Stetson United States	32	5.8k 2.0×	3.5k 1.5×	1000 1.1×	1.2k 1.6×	939 2.0×	40	7.7k
Florian Heil United States	9	2.8k 0.9×	1.3k 0.6×	669 0.7×	337 0.4×	606 1.3×	11	4.1k
Chae Gyu Park United States	34	4.2k 1.4×	1.5k 0.7×	540 0.6×	295 0.4×	575 1.2×	76	5.3k
Tanja I. Näslund Sweden	12	2.4k 0.8×	1.5k 0.6×	797 0.9×	493 0.6×	321 0.7×	17	3.3k

Countries citing papers authored by Leonie Unterholzner

Since Specialization

Citations

This map shows the geographic impact of Leonie Unterholzner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leonie Unterholzner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leonie Unterholzner more than expected).

Fields of papers citing papers by Leonie Unterholzner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leonie Unterholzner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leonie Unterholzner. The network helps show where Leonie Unterholzner may publish in the future.

Co-authorship network of co-authors of Leonie Unterholzner

This figure shows the co-authorship network connecting the top 25 collaborators of Leonie Unterholzner. A scholar is included among the top collaborators of Leonie Unterholzner based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leonie Unterholzner. Leonie Unterholzner is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

Unterholzner, Leonie, et al.. (2023). DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling. Essays in Biochemistry. 67(6). 905–918. 13 indexed citations

Gu, Lili, Gareth Brady, Susan Carpenter, et al.. (2022). Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7. Nature Communications. 13(1). 14–14. 33 indexed citations

Fan, Xiaojiao, Jiansheng Jiang, Dan Zhao, et al.. (2021). Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Research. 49(5). 2959–2972. 12 indexed citations

Unterholzner, Leonie, et al.. (2021). Structural and Evolutionary Insights Into the Binding of Host Receptors by the Rabies Virus Glycoprotein. Frontiers in Cellular and Infection Microbiology. 11. 736114–736114. 6 indexed citations

Unterholzner, Leonie & Gillian Dunphy. (2019). cGAS-independent STING activation in response to DNA damage. Molecular & Cellular Oncology. 6(4). 1558682–1558682. 31 indexed citations

Unterholzner, Leonie, et al.. (2018). Camouflage and interception: how pathogens evade detection by intracellular nucleic acid sensors. Immunology. 156(3). 217–227. 22 indexed citations

Dunphy, Gillian, Sinéad Flannery, Dympna J. Connolly, et al.. (2018). Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage. Molecular Cell. 71(5). 745–760.e5. 470 indexed citations breakdown →

Dunphy, Gillian, Ismar R. Haga, Rangeetha J. Naik, et al.. (2017). IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. Nature Communications. 8(1). 14392–14392. 257 indexed citations

Unterholzner, Leonie. (2013). The interferon response to intracellular DNA: Why so many receptors?. Immunobiology. 218(11). 1312–1321. 193 indexed citations

10.

Mansur, Daniel Santos, Carlos Maluquer de Motes, Leonie Unterholzner, et al.. (2013). Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence. PLoS Pathogens. 9(2). e1003183–e1003183. 93 indexed citations

11.

Horan, Kristy, Kathrine Hansen, Martin R. Jakobsen, et al.. (2013). Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors. The Journal of Immunology. 190(5). 2311–2319. 165 indexed citations

12.

Jin, Tengchuan, Andrew Perry, Jiansheng Jiang, et al.. (2012). Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity. 36(4). 561–571. 437 indexed citations

13.

Unterholzner, Leonie, Rebecca P. Sumner, Marcin Baran, et al.. (2011). Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7. PLoS Pathogens. 7(9). e1002247–e1002247. 144 indexed citations

14.

Unterholzner, Leonie, Sinéad E. Keating, Marcin Baran, et al.. (2010). IFI16 is an innate immune sensor for intracellular DNA. Nature Immunology. 11(11). 997–1004. 1300 indexed citations breakdown →

15.

Bowie, Andrew & Leonie Unterholzner. (2008). Viral evasion and subversion of pattern-recognition receptor signalling. Nature reviews. Immunology. 8(12). 911–922. 585 indexed citations breakdown →

16.

Unterholzner, Leonie & Andrew Bowie. (2007). The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities. Biochemical Pharmacology. 75(3). 589–602. 101 indexed citations

17.

Fukuhara, N., J. Ebert, Leonie Unterholzner, et al.. (2005). SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway. Molecular Cell. 17(4). 537–547. 192 indexed citations

18.

Bono, Fulvia, J. Ebert, Leonie Unterholzner, et al.. (2004). Molecular insights into the interaction of PYM with the Mago–Y14 core of the exon junction complex. EMBO Reports. 5(3). 304–310. 79 indexed citations

19.

Unterholzner, Leonie & Elisa Izaurralde. (2004). SMG7 Acts as a Molecular Link between mRNA Surveillance and mRNA Decay. Molecular Cell. 16(4). 587–596. 240 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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