Leonard A. Zwelling

6.5k total citations · 2 hit papers
128 papers, 5.6k citations indexed

About

Leonard A. Zwelling is a scholar working on Molecular Biology, Oncology and Public Health, Environmental and Occupational Health. According to data from OpenAlex, Leonard A. Zwelling has authored 128 papers receiving a total of 5.6k indexed citations (citations by other indexed papers that have themselves been cited), including 99 papers in Molecular Biology, 54 papers in Oncology and 17 papers in Public Health, Environmental and Occupational Health. Recurrent topics in Leonard A. Zwelling's work include Cancer therapeutics and mechanisms (68 papers), DNA and Nucleic Acid Chemistry (36 papers) and DNA Repair Mechanisms (21 papers). Leonard A. Zwelling is often cited by papers focused on Cancer therapeutics and mechanisms (68 papers), DNA and Nucleic Acid Chemistry (36 papers) and DNA Repair Mechanisms (21 papers). Leonard A. Zwelling collaborates with scholars based in United States, France and United Kingdom. Leonard A. Zwelling's co-authors include Kurt W. Kohn, Yves Pommier, Donna Kerrigan, Ronald E. Schwartz, Stephen Michaels, Tom Anderson, Michael R. Mattern, Leonard C. Erickson, K W Kohn and Lynn Silberman and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Leonard A. Zwelling

127 papers receiving 5.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin

1981 340 citations Leonard A. Zwelling, Stephen Michaels et al. Biochemistry profile →
DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity.

1979 340 citations Leonard A. Zwelling, Kurt W. Kohn et al. PubMed profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Leonard A. Zwelling United States	41	3.9k	2.4k	875	588	514	128	5.6k
Warren E. Ross United States	36	3.4k 0.9×	1.7k 0.7×	667 0.8×	355 0.6×	546 1.1×	56	4.2k
William T. Beck United States	50	5.3k 1.4×	4.2k 1.7×	560 0.6×	626 1.1×	429 0.8×	131	7.4k
Bridget T. Hill United Kingdom	39	3.0k 0.8×	2.2k 0.9×	555 0.6×	551 0.9×	180 0.4×	193	5.3k
Giovanni Capranico Italy	47	4.9k 1.3×	2.0k 0.8×	1.0k 1.2×	524 0.9×	948 1.8×	144	6.2k
Graziella Pratesi Italy	42	3.7k 0.9×	3.9k 1.6×	758 0.9×	1.1k 1.8×	395 0.8×	147	6.7k
Rosanna Supino Italy	37	3.0k 0.8×	1.7k 0.7×	593 0.7×	803 1.4×	230 0.4×	109	4.9k
John F. Smyth United Kingdom	52	3.7k 1.0×	2.9k 1.2×	305 0.3×	921 1.6×	225 0.4×	202	8.2k
Melinda G. Hollingshead United States	45	3.9k 1.0×	1.9k 0.8×	1.1k 1.3×	1.2k 2.1×	277 0.5×	167	6.9k
Randall K. Johnson United States	48	4.7k 1.2×	3.2k 1.3×	2.1k 2.4×	494 0.8×	546 1.1×	142	8.2k
Saul H. Rosenberg United States	44	5.6k 1.4×	2.3k 1.0×	1.7k 1.9×	545 0.9×	149 0.3×	118	8.2k

Countries citing papers authored by Leonard A. Zwelling

Since Specialization

Citations

This map shows the geographic impact of Leonard A. Zwelling's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leonard A. Zwelling with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leonard A. Zwelling more than expected).

Fields of papers citing papers by Leonard A. Zwelling

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leonard A. Zwelling. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leonard A. Zwelling. The network helps show where Leonard A. Zwelling may publish in the future.

Co-authorship network of co-authors of Leonard A. Zwelling

This figure shows the co-authorship network connecting the top 25 collaborators of Leonard A. Zwelling. A scholar is included among the top collaborators of Leonard A. Zwelling based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leonard A. Zwelling. Leonard A. Zwelling is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kantarjian, Hagop M. & Leonard A. Zwelling. (2013). Cancer drug prices and the free‐market forces. Cancer. 119(22). 3903–3905. 19 indexed citations

Zwelling, Leonard A., et al.. (2013). Saving Medicare through Patient-Centered Changes — The Case of Injectables. New England Journal of Medicine. 368(17). 1572–1573. 4 indexed citations

Asano, Takeshi, Eugenie S. Kleinerman, Leonard A. Zwelling, Zhichao Zhou, & Yoshitaka Fukunaga. (2005). Adenovirus-mediated human topoisomerase IIα gene transfer increases the sensitivity of etoposide-resistant human and mouse breast cancer cells. Acta Oncologica. 44(3). 240–247. 11 indexed citations

Asano, Takeshi, et al.. (1996). Transfection of a human topoisomerase II alpha gene into etoposide-resistant human breast tumor cells sensitizes the cells to etoposide.. PubMed. 8(3). 101–10. 13 indexed citations

Zwelling, Leonard A., Elise S. Bales, Elizabeth Altschuler, & Janice Mayes. (1993). Circumvention of resistance by doxorubicin, but not by idarubicin, in a human leukemia cell line containing an intercalator-resistant form of topoisomerase II: evidence for a non-topoisomerase II-mediated mechanism of doxorubicin cytotoxicity. Biochemical Pharmacology. 45(2). 516–520. 19 indexed citations

Mayes, Janice, et al.. (1993). Further characterization of an amsacrine-resistant line of HL-60 human leukemia cells and its topoisomerase II. Biochemical Pharmacology. 46(4). 699–707. 8 indexed citations

Ellis, Amy, Roderick T. Bunch, Joyce K. Randolph, et al.. (1992). Components of intrinsic drug resistance in the rat hepatoma. Biochemical Pharmacology. 43(2). 331–342. 8 indexed citations

Whelan, Richard D. H., et al.. (1991). A lack of detectable modification of topoisomerase II activity in a series of human tumor cell lines expressing only low levels of etoposide resistance. International Journal of Cancer. 47(6). 899–902. 9 indexed citations

Fan, Dominic, Corazon D. Bucana, Catherine A. O’Brian, et al.. (1990). Enhancement of murine tumor cell sensitivity to adriamycin by presentation of the drug in phosphatidylcholine-phosphatidylserine liposomes.. PubMed. 50(12). 3619–26. 55 indexed citations

10.

Zwelling, Leonard A., Janice Mayes, Karl Deisseroth, et al.. (1990). A Restriction Fragment Length Polymorphism for Human Topoisomerase II: Possible Relationship to Drug-Resistance. PubMed. 2(11). 357–361. 8 indexed citations

11.

Zwelling, Leonard A.. (1989). Topoisomerase II as a target of antileukemia drugs: a review of controversial areas.. PubMed. 3(3). 101–12. 39 indexed citations

12.

Kleinerman, Eugenie S., et al.. (1989). Lithium Chloride Stimulates Human Monocytes to Secrete Tumor Necrosis Factor/Cachectin. Journal of Leukocyte Biology. 46(5). 484–492. 35 indexed citations

13.

Wassermann, Karsten, Leonard A. Zwelling, Lynn Silberman, et al.. (1986). Effects of 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin and doxorubicin on the survival, DNA integrity, and nucleolar morphology of human leukemia cells in vitro.. PubMed. 46(8). 4041–6. 22 indexed citations

14.

Zwelling, Leonard A., Elihu H. Estey, Lynn Silberman, & Walter N. Hittelman. (1985). m-AMSA-induced DNA strand breaks: A potential measure of the malignant phenotype. Proceedings of the American Association for Cancer Research. 26. 3 indexed citations

15.

Zwelling, Leonard A., Lynn Silberman, & Elihu H. Estey. (1985). Biochemical basis for tumoricidal synergism between antimetabolites and DNA intercalating agents. 37(4). 187–192. 1 indexed citations

16.

Kerrigan, Donna, et al.. (1984). Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.. PubMed. 44(12 Pt 1). 5583–93. 24 indexed citations

17.

Johnston, James B., et al.. (1983). Comparison of dna scission and cytotoxicity produced by adriamycin and 5-iminodaunorubicin in human colon carcinoma cells. Biochemical Pharmacology. 32(14). 2255–2258. 13 indexed citations

18.

Pommier, Yves, Donna Kerrigan, Ronald E. Schwartz, & Leonard A. Zwelling. (1982). The formation and resealing of intercalator-induced DNA strand breaks in isolated L1210 cell nuclei. Biochemical and Biophysical Research Communications. 107(2). 576–583. 68 indexed citations

19.

Erickson, Leonard C., Leonard A. Zwelling, Jonathan M. Ducore, Nancy A. Sharkey, & Kurt W. Kohn. (1981). Differential cytotoxicity and DNA cross-linking in normal and transformed human fibroblasts treated with cis-diamminedichloroplatinum(II).. PubMed. 41(7). 2791–4. 42 indexed citations

20.

Zwelling, Leonard A., et al.. (1981). Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin. Biochemistry. 20(23). 6553–6563. 340 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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