Kin Chan

22.5k citations

38 papers · 1.6k indexed · h-index 19

Impact in

Cancer Research top 5%
- Cancer Genomics and Diagnostics
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Toxicology top 2%

Papers in ⓘ

Aging 2
Cancer Research 17
- Cancer Genomics and Diagnostics 6
- MicroRNA in disease regulation 6

Co-authors: Dmitry A. Gordenin (6 shared papers)Melvin Toh (3 shared papers)Simon Law (14 shared papers)Steven A. Roberts (3 shared papers)Joan F. Sterling (2 shared papers)Michael A. Resnick (2 shared papers)Piotr A. Mieczkowski (3 shared papers)David C. Fargo (3 shared papers)
Journals: Clinical Cancer Research (2 papers)Theranostics (2 papers)Cancer Letters (2 papers)PLoS Genetics (2 papers)Cancer Research and Treatment (1 paper)
Partner nations: Hong Kong United States China

In The Last Decade

Kin Chan

38 papers receiving 1.6k citations

Peers

Countries citing papers authored by Kin Chan

Since Specialization

Citations

This map shows the geographic impact of Kin Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kin Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kin Chan more than expected).

Fields of papers citing papers by Kin Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kin Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kin Chan. The network helps show where Kin Chan may publish in the future.

Co-authors

The 25 scholars most cited alongside Kin Chan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kin Chan Line = papers co-authored together Kin Chan links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 38 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers Nature Genetics ·Kin Chan, Steven A. Roberts, Leszek J. Klimczak, Joan F. Sterling, Natalie Saini, Ewa P. Malc, Jaegil Kim, David J. Kwiatkowski, David C. Fargo, Piotr A. Mieczkowski, Gad Getz, Dmitry A. Gordenin	2015	284
2	Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration Cancer Letters ·Kin Chan, Fan Yan Meng, Qian Li, Cheong Yip Ho, Tsz Shan Lam, Yu To, Wai Him Lee, Miao Li, Kee Hung Chu, Melvin Toh	2010	202
3	Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562 Cancer Letters ·Kin Chan, Kwan Li, Shiu Lam Liu, Kee Hung Chu, Melvin Toh, Wei Xie	2009	112
4	MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF Oncogene ·Binkui Li, Wen Xu, Han Li, Kin Chan, Sai Wah Tsao, N. P.Y. Lee, Simon Law, Li‐Yan Xu, ENG Li, Kwok Wah Chan, Yanru Qin, Xin‐Yuan Guan, Qing‐Yu He, Annie L.M. Cheung	2017	106
5	Clusters of Multiple Mutations: Incidence and Molecular Mechanisms Annual Review of Genetics ·Kin Chan, Dmitry A. Gordenin	2015	94
6	Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression Nature Communications ·Wen Xu, Bin Li, Xin‐Yuan Guan, Sookja Kim Chung, Yang Wang, Yim Ling Yip, Simon Law, Kin Chan, Nikki P.Y. Lee, Kwok Wah Chan, Xu Li, En‐Min Li, Sai Wah Tsao, Qing‐Yu He, Annie L.M. Cheung	2017	81
7	Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent PLoS Genetics ·Kin Chan, Joan F. Sterling, Steven A. Roberts, Ashok S. Bhagwat, Michael A. Resnick, Dmitry A. Gordenin	2012	75
8	Overexpression of transferrin receptor CD71 and its tumorigenic properties in esophageal squamous cell carcinoma Oncology Reports ·Kin Chan, Mei Yuk Choi, Kenneth Lai, Winnie Tan, Lai Nar Tung, Ho Yu Lam, Daniel King Hung Tong, Nikki P. Lee, Simon Law	2014	66
9	The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts PLoS Genetics ·Natalie Saini, Steven A. Roberts, Leszek J. Klimczak, Kin Chan, Sara A. Grimm, Shuang-Shuang Dai, David C. Fargo, Jayne C. Boyer, William K. Kaufmann, Jack A. Taylor, Eunjung Lee, Isidro Cortés‐Ciriano, Peter J. Park, Shepherd H. Schurman, Ewa P. Malc, Piotr A. Mieczkowski, Dmitry A. Gordenin	2016	60
10	The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis DNA repair ·Kin Chan, Michael A. Resnick, Dmitry A. Gordenin	2013	56
11	Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance Clinical Cancer Research ·Bin Li, Wen Xu, Xin‐Yuan Guan, Yan Qin, Simon Law, Nikki Pui Yue Lee, Kin Chan, Pui Ying Tam, Yuk Yin Li, Kwok Wah Chan, Hiu Fung Yuen, Sai Wah Tsao, Qing‐Yu He, Annie L.M. Cheung	2015	53
12	Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance Theranostics ·Bin Li, Hong Pan, Can‐Can Zheng, Wei Dai, Wen‐You Chen, Qing-Sheng Yang, Han Liang, Sai Wah Tsao, Kin Chan, Nikki Pui Yue Lee, Simon Law, Xu Li, En‐Min Li, Kwok Wah Chan, Yan Qin, Xin‐Yuan Guan, Maria Li Lung, Qing‐Yu He, Wen Xu, Annie LM Cheung	2019	49
13	The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer International Journal of Cancer ·Ahmed Aribi, Sigal Gery, Der‐Horng Lee, Nils H. Thoennissen, Gabriela B. Thoennissen, Rocio Alvarez, Quoc Ho, Kunik Lee, Ngan Doan, Kin Chan, Melvin Toh, Jonathan Said, H. Phillip Koeffler	2012	49
14	Decoding complex patterns of genomic rearrangement in hepatocellular carcinoma Genomics ·Julio Fernandez-Banet, Nikki P. Lee, Kin Chan, Huan Gao, Xiao Liu, Wing‐Kin Sung, Winnie Tan, Sheung Tat Fan, Ronnie T.P. Poon, Shiyong Li, Keith A. Ching, Paul A. Rejto, Mao Mao, Zhengyan Kan	2014	44
15	Whole‐exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma The Journal of Pathology ·Wei Dai, Josephine Mun Yee Ko, Sheyne Sta Ana Choi, Zhouyou Yu, Luwen Ning, Hong Zheng, Vinod Gopalan, Kin Chan, Nikki P. Lee, Kwok Wah Chan, Simon Law, Alfred K. Lam, Maria Li Lung	2017	42
16	MicroRNA‐338‐5p reverses chemoresistance and inhibits invasion of esophageal squamous cell carcinoma cells by targeting Id‐1 Cancer Science ·Han Liang, Di Cui, Bin Li, Wen Xu, Alfred K. Lam, Kin Chan, Yun Zhu, Nikki P.Y. Lee, Simon Law, Xin‐Yuan Guan, Yan Qin, Kwok Wah Chan, Stephanie Ma, Sai Wah Tsao, Annie L.M. Cheung	2019	35
17	Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation PLoS Biology ·Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam Burkholder, David C. Fargo, Dmitry A. Gordenin	2019	31
18	Multiple Specific Binding Targets for Inhaled Anesthetics in the Mammalian Brain Journal of Pharmacology and Experimental Therapeutics ·Maryellen F. Eckenhoff, Kin Chan, Roderic G. Eckenhoff	2002	27
19	Serum microRNA-193b as a promising biomarker for prediction of chemoradiation sensitivity in esophageal squamous cell carcinoma patients Oncology Letters ·Chung Yip Chan, Kenneth Lai, Enders K. Ng, Mei Yee Karrie Kiang, Tiffany Kwok, Hector Wang, Kwok Wah Chan, Tsz Ting Law, Daniel King Hung Tong, Kin Chan, Nikki P. Lee, Simon Law	2017	19
20	Role of AMPK signaling in mediating the anticancer effects of silibinin in esophageal squamous cell carcinoma Expert Opinion on Therapeutic Targets ·Jin Li, Bin Li, Wen Xu, Kwok Wah Chan, Xin‐Yuan Guan, Yan Qin, Nikki Pui Yue Lee, Kin Chan, Simon Law, Sai Wah Tsao, Annie LM Cheung	2015	18

About Kin Chan

Kin Chan is a scholar working on Aging, Cancer Research, Toxicology, Molecular Biology and Transplantation, having authored 38 papers that have together received 1.6k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (6 papers), Cancer Genomics and Diagnostics (6 papers), MicroRNA in disease regulation (6 papers), DNA Repair Mechanisms (5 papers), RNA modifications and cancer (4 papers), Cancer-related gene regulation (4 papers), Pancreatic and Hepatic Oncology Research (4 papers) and Bioactive Compounds and Antitumor Agents (3 papers). The work is most often cited by research in Cancer Research (551 citations), Toxicology (94 citations), Molecular Biology (1.1k citations), Genetics (291 citations) and Oncology (277 citations). Kin Chan has collaborated with scholars based in Hong Kong, United States and China. Frequent co-authors include Dmitry A. Gordenin, Melvin Toh, Simon Law, Steven A. Roberts, Joan F. Sterling, Michael A. Resnick, Piotr A. Mieczkowski, David C. Fargo, Natalie Saini and Ewa P. Malc. Their work appears in journals such as Clinical Cancer Research, Theranostics, Cancer Letters, PLoS Genetics and Cancer Research and Treatment.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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