Jyrki Heino

13.4k total citations · 1 hit paper
196 papers, 10.7k citations indexed

About

Jyrki Heino is a scholar working on Immunology and Allergy, Molecular Biology and Cell Biology. According to data from OpenAlex, Jyrki Heino has authored 196 papers receiving a total of 10.7k indexed citations (citations by other indexed papers that have themselves been cited), including 125 papers in Immunology and Allergy, 67 papers in Molecular Biology and 61 papers in Cell Biology. Recurrent topics in Jyrki Heino's work include Cell Adhesion Molecules Research (125 papers), Protease and Inhibitor Mechanisms (45 papers) and Cellular Mechanics and Interactions (36 papers). Jyrki Heino is often cited by papers focused on Cell Adhesion Molecules Research (125 papers), Protease and Inhibitor Mechanisms (45 papers) and Cellular Mechanics and Interactions (36 papers). Jyrki Heino collaborates with scholars based in Finland, United States and Canada. Jyrki Heino's co-authors include Johanna Ivaska, Joan Massagué, Hannu Larjava, Veli‐Matti Kähäri, Jarmo Käpylä, Leeni Koivisto, Ronald A. Ignotz, Mark S. Johnson, Lari Häkkinen and Liisa Nissinen and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Jyrki Heino

193 papers receiving 10.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 596 citations Jyrki Heino et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jyrki Heino Finland	56	4.3k	4.1k	2.6k	1.9k	1.2k	196	10.7k
Jean E. Schwarzbauer United States	57	3.6k 0.8×	4.6k 1.1×	3.6k 1.4×	2.2k 1.2×	967 0.8×	152	11.0k
Monique Aumailley Germany	60	4.8k 1.1×	6.2k 1.5×	4.3k 1.6×	1.9k 1.0×	1.0k 0.9×	132	11.8k
Donald Gullberg Norway	51	3.3k 0.8×	3.6k 0.9×	2.4k 0.9×	1.2k 0.6×	1.0k 0.8×	122	8.0k
Hannu Larjava Canada	58	3.0k 0.7×	2.6k 0.6×	2.6k 1.0×	2.0k 1.0×	1.1k 0.9×	194	10.8k
Jonathan Jones United States	61	3.9k 0.9×	3.6k 0.9×	4.8k 1.9×	899 0.5×	1.1k 0.9×	168	10.3k
Peter D. Yurchenco United States	61	6.9k 1.6×	6.7k 1.6×	5.3k 2.0×	1.8k 0.9×	1.1k 1.0×	120	14.3k
Kristofer Rubin Sweden	58	4.3k 1.0×	2.5k 0.6×	2.0k 0.8×	1.6k 0.8×	2.2k 1.9×	151	11.3k
Takako Sasaki Germany	70	6.1k 1.4×	3.7k 0.9×	3.2k 1.2×	2.5k 1.3×	1.1k 1.0×	213	12.9k
Mats Paulsson Germany	73	6.5k 1.5×	5.9k 1.4×	5.5k 2.1×	2.1k 1.1×	892 0.8×	245	16.4k
Richard W. Farndale United Kingdom	68	4.9k 1.1×	4.2k 1.0×	2.6k 1.0×	2.1k 1.1×	1.3k 1.1×	233	19.1k

Countries citing papers authored by Jyrki Heino

Since Specialization

Citations

This map shows the geographic impact of Jyrki Heino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jyrki Heino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jyrki Heino more than expected).

Fields of papers citing papers by Jyrki Heino

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jyrki Heino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jyrki Heino. The network helps show where Jyrki Heino may publish in the future.

Co-authorship network of co-authors of Jyrki Heino

This figure shows the co-authorship network connecting the top 25 collaborators of Jyrki Heino. A scholar is included among the top collaborators of Jyrki Heino based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jyrki Heino. Jyrki Heino is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Nissinen, Liisa, Elina Siljamäki, Pekka Rappu, et al.. (2025). Expression of C1q by Macrophages and Fibroblasts in Tumor Microenvironment Is Associated with Progression and Metastasis of Cutaneous Squamous Cell Carcinoma. Journal of Investigative Dermatology. 145(11). 2854–2868.e4. 2 indexed citations

Nissinen, Liisa, Elina Siljamäki, Teijo Pellinen, et al.. (2025). C5aR1 Promotes Invasion, Metastasis, and Poor Prognosis in Cutaneous Squamous Cell Carcinoma. American Journal Of Pathology. 195(6). 1158–1171. 2 indexed citations

Jokinen, Johanna, Kalle Sipilä, Pekka Rappu, et al.. (2024). Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice. iScience. 27(2). 108914–108914.

Salo, Antti M., Pekka Rappu, M. Kristian Koski, et al.. (2023). Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets. Matrix Biology. 125. 73–87. 16 indexed citations

Siljamäki, Elina, Pilvi Riihilä, Liisa Nissinen, et al.. (2023). Inhibition of TGF-β signaling, invasion, and growth of cutaneous squamous cell carcinoma by PLX8394. Oncogene. 42(49). 3633–3647. 5 indexed citations

Farndale, Richard W., Arnoud Sonnenberg, C. Michael DiPersio, et al.. (2022). What does it take to be a collagen receptor?. Matrix Biology. 115. 128–132. 7 indexed citations

Nissinen, Liisa, Pilvi Riihilä, Markku Kallajoki, et al.. (2021). C1r Upregulates Production of Matrix Metalloproteinase-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma. Journal of Investigative Dermatology. 142(5). 1478–1488.e9. 35 indexed citations

Rappu, Pekka, et al.. (2020). Interaction between prostate cancer cells and prostate fibroblasts promotes accumulation and proteolytic processing of basement membrane proteins. The Prostate. 80(9). 715–726. 14 indexed citations

Rappu, Pekka, Antti M. Salo, Johanna Myllyharju, & Jyrki Heino. (2019). Role of prolyl hydroxylation in the molecular interactions of collagens. Essays in Biochemistry. 63(3). 325–335. 106 indexed citations

10.

Rappu, Pekka, et al.. (2018). The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis. The Prostate. 78(8). 583–594. 9 indexed citations

11.

Roche, Frédéric, Kalle Sipilä, Satoshi Honjo, et al.. (2015). Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with α2 integrin. Matrix Biology. 48. 89–99. 9 indexed citations

12.

Koivisto, Leeni, Jyrki Heino, Lari Häkkinen, & Hannu Larjava. (2013). Integrins in Wound Healing. Advances in Wound Care. 3(12). 762–783. 171 indexed citations

13.

Veit, Guido, Daniela Zwolanek, Beate Eckes, et al.. (2011). Collagen XXIII, Novel Ligand for Integrin α2β1 in the Epidermis. Journal of Biological Chemistry. 286(31). 27804–27813. 34 indexed citations

14.

Nymalm, Yvonne, J. Santeri Puranen, Thomas K.M. Nyholm, et al.. (2004). Jararhagin-derived RKKH Peptides Induce Structural Changes in α1I Domain of Human Integrin α1β1. Journal of Biological Chemistry. 279(9). 7962–7970. 32 indexed citations

15.

Heino, Jyrki. (2003). Mechanisms and Consequences of Integrin Mediated Cell Adhesion to Collagen. 35(3). 155–161.

16.

Kääriäinen, Minna, et al.. (2001). Regulation of α7 integrin by mechanical stress during skeletal muscle regeneration. Neuromuscular Disorders. 11(4). 360–369. 21 indexed citations

17.

Ivaska, Johanna & Jyrki Heino. (2000). Adhesion receptors and cell invasion: mechanisms of integrin-guided degradation of extracellular matrix. Cellular and Molecular Life Sciences. 57(1). 16–24. 129 indexed citations

18.

Heino, Jyrki. (1993). Integrin-type Extracellular Matrix Receptors in Cancer and Inflammation. Annals of Medicine. 25(4). 335–342. 35 indexed citations

19.

Häkkinen, Lari, Antti Yli‐Urpo, Jyrki Heino, & Hannu Larjava. (1988). Attachment and spreading of human gingival fibroblasts on potentially bioactive glasses in vitro. Journal of Biomedical Materials Research. 22(11). 1043–1059. 28 indexed citations

20.

Heino, Jyrki, Hannu Larjava, Victor C. Duance, & Risto Penttinen. (1986). Distribution and biosynthesis of connective tissue components by synovial fibroblasts cultured with mononuclear inflammatory cells.. PubMed Central. 67(5). 637–46. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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