Joseph S. Handler

4.4k total citations · 2 hit papers
47 papers, 3.5k citations indexed

About

Joseph S. Handler is a scholar working on Molecular Biology, Cell Biology and Surgery. According to data from OpenAlex, Joseph S. Handler has authored 47 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Molecular Biology, 15 papers in Cell Biology and 11 papers in Surgery. Recurrent topics in Joseph S. Handler's work include Aldose Reductase and Taurine (14 papers), Ion Transport and Channel Regulation (14 papers) and Electrolyte and hormonal disorders (8 papers). Joseph S. Handler is often cited by papers focused on Aldose Reductase and Taurine (14 papers), Ion Transport and Channel Regulation (14 papers) and Electrolyte and hormonal disorders (8 papers). Joseph S. Handler collaborates with scholars based in United States, Russia and Czechia. Joseph S. Handler's co-authors include Jack Orloff, H. Moo Kwon, Stephen C. Dahl, Seung Kyoon Woo, Hiroshi Miyakawa, Robert Blumenthal, Paul R. Dragsten, Sune Bergström, Hyug Moo Kwon and Martin Goldberg and has published in prestigious journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Joseph S. Handler

46 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

THE SIMILARITY OF EFFECTS OF VASOPRESSIN, ADENOSINE-3′,5′-PHOSPHATE (CYCLIC AMP) AND THEOPHYLLINE ON THE TOAD BLADDER*

1962 342 citations Jack Orloff, Joseph S. Handler profile →
Effect of Prostaglandin (PGEI) on the Permeability Response of Toad Bladder to Vasopressin, Theophylline and Adenosine 3′,5′-monophosphate

1965 223 citations Jack Orloff, Joseph S. Handler et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Joseph S. Handler United States	30	1.8k	1.2k	594	592	538	47	3.5k
Claude Labrie Canada	47	2.3k 1.3×	685 0.6×	819 1.4×	153 0.3×	295 0.5×	123	8.0k
A. García-Pérez United States	25	1.3k 0.7×	946 0.8×	199 0.3×	465 0.8×	395 0.7×	36	2.5k
Atsushi Yamauchi Japan	39	2.0k 1.1×	864 0.7×	406 0.7×	653 1.1×	682 1.3×	168	5.5k
Eric Féraille Switzerland	42	3.1k 1.7×	413 0.3×	1.0k 1.8×	255 0.4×	531 1.0×	92	4.4k
Anikó Náray‐Fejes‐Tóth United States	39	2.8k 1.6×	210 0.2×	843 1.4×	231 0.4×	305 0.6×	90	4.5k
Françoise Cluzeaud France	38	3.0k 1.7×	405 0.3×	578 1.0×	194 0.3×	566 1.1×	71	4.5k
Ronald N. Rubin United States	37	3.3k 1.9×	835 0.7×	241 0.4×	131 0.2×	887 1.6×	154	6.0k
H. Moo Kwon United States	34	1.9k 1.1×	2.1k 1.8×	233 0.4×	1.1k 1.8×	697 1.3×	58	4.1k
Isidore S. Edelman United States	36	2.4k 1.3×	237 0.2×	517 0.9×	121 0.2×	664 1.2×	63	5.1k
R. Taugner Germany	33	1.8k 1.0×	235 0.2×	317 0.5×	272 0.5×	566 1.1×	161	3.5k

Countries citing papers authored by Joseph S. Handler

Since Specialization

Citations

This map shows the geographic impact of Joseph S. Handler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph S. Handler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph S. Handler more than expected).

Fields of papers citing papers by Joseph S. Handler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph S. Handler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph S. Handler. The network helps show where Joseph S. Handler may publish in the future.

Co-authorship network of co-authors of Joseph S. Handler

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph S. Handler. A scholar is included among the top collaborators of Joseph S. Handler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph S. Handler. Joseph S. Handler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Horio, Masaru, Hajime Nakahama, Naohiko Ueda, et al.. (2015). Kidney-Derived Cells Show Multidrug Secretory Transport. Contributions to nephrology. 95. 143–148.

Woo, Seung Kyoon, et al.. (2002). Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity. American Journal of Physiology-Cell Physiology. 282(1). C49–C58. 61 indexed citations

Handler, Joseph S. & Hyug Moo Kwon. (2001). Transcriptional regulation by changes in tonicity. Kidney International. 60(2). 408–411. 56 indexed citations

Woo, Seung Kyoon, Ki‐Hwan Han, Young Ho Kim, et al.. (2001). Hydration Status Affects Nuclear Distribution of Transcription Factor Tonicity Responsive Enhancer Binding Protein in Rat Kidney. Journal of the American Society of Nephrology. 12(11). 2221–2230. 66 indexed citations

Handler, Joseph S. & H. Moo Kwon. (2001). Cell and Molecular Biology of Organic Osmolyte Accumulation in Hypertonic Renal Cells. The Nephron journals/Nephron journals. 87(2). 106–110. 39 indexed citations

Atta, Mohamed G., Stephen C. Dahl, H. Moo Kwon, & Joseph S. Handler. (1999). Tyrosine kinase inhibitors and immunosuppressants perturb the myo-inositol but not the betaine cotransporter in isotonic and hypertonic MDCK cells. Kidney International. 55(3). 956–962. 19 indexed citations

Miyakawa, Hiroshi, Jong S. Rim, Joseph S. Handler, & Hyug Moo Kwon. (1999). Identification of the second tonicity-responsive enhancer for the betaine transporter (BGT1) gene. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1446(3). 359–364. 48 indexed citations

Wagner, Carsten A., Carola Stegen, Stefan Bröer, et al.. (1999). Functional Characterization of the Betaine/γ-Aminobutyric Acid Transporter BGT-1 Expressed in Xenopus Oocytes. Journal of Biological Chemistry. 274(24). 16709–16716. 63 indexed citations

Rim, Jong S., Mohamed G. Atta, Stephen C. Dahl, et al.. (1998). Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region. Journal of Biological Chemistry. 273(32). 20615–20621. 148 indexed citations

10.

Durso, Raymon, James Evans, George Szabó, et al.. (1997). Central levodopa metabolism in Parkinson's disease after administration of stable isotope—labeled levodopa. Annals of Neurology. 42(3). 300–304. 5 indexed citations

11.

Handler, Joseph S. & H. Moo Kwon. (1997). Kidney Cell Survival in High Tonicity. Comparative Biochemistry and Physiology Part A Physiology. 117(3). 301–306. 23 indexed citations

12.

Rim, Jong S., et al.. (1997). The Canine Sodium/myo-Inositol Cotransporter Gene: Structural Organization and Characterization of the Promoter. Archives of Biochemistry and Biophysics. 341(1). 193–199. 12 indexed citations

13.

Handler, Joseph S. & H. Moo Kwon. (1996). Regulation of the myo-inositol and betaine cotransporters by tonicity. Kidney International. 49(6). 1682–1683. 35 indexed citations

14.

Kwon, H. Moo & Joseph S. Handler. (1995). Cell volume regulated transporters of compatible osmolytes. Current Opinion in Cell Biology. 7(4). 465–471. 123 indexed citations

15.

Surratt, Christopher K., et al.. (1993). Sodium- and chloride-dependent transporters in brain, kidney, and gut. Current Opinion in Nephrology & Hypertension. 2(5). 744–760. 15 indexed citations

16.

Horio, Masaru, Ira Pastan, Michael M. Gottesman, & Joseph S. Handler. (1990). Transepithelial transport of vinblastine by kidney-derived cell lines. Application of a new kinetic model to estimate in situ Km of the pump. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1027(2). 116–122. 67 indexed citations

17.

Handler, Joseph S., et al.. (1989). [37] Cultures as epithelial models: Porous-bottom culture dishes for studying transport and differentiation. Methods in enzymology on CD-ROM/Methods in enzymology. 736–744. 18 indexed citations

18.

Harris, H. William & Joseph S. Handler. (1988). The role of membrane turnover in the water permeability response to antidiuretic hormone. The Journal of Membrane Biology. 103(3). 207–216. 43 indexed citations

19.

Handler, Joseph S.. (1985). Transport in cultured epithelia. Current Eye Research. 4(4). 317–322. 3 indexed citations

20.

Sugita, Minoru, et al.. (1973). The effect of some nucleotides and related compounds on sodium transport and water permability of the urinary bladder of the toad. Comparative Biochemistry and Physiology Part A Physiology. 45(1). 157–167. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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