Jan Šimák

8.3k citations

55 papers · 1.8k indexed · h-index 23

Impact in

Hematology top 5%
- Platelet Disorders and Treatments
Biomaterials top 5%
- Nanoparticle-Based Drug Delivery

Papers in ⓘ

Molecular Biology 28
- Prion Diseases and Protein Misfolding 12
- Extracellular vesicles in disease 7
Hematology 13
- Platelet Disorders and Treatments 11
- Blood Coagulation and Thrombosis Mechanisms 4

Co-authors: Monique P. Gelderman (7 shared papers)Karel Holada (25 shared papers)Jaroslav G. Vostal (13 shared papers)Jana Šemberová (4 shared papers)Silvia H. De Paoli Lacerda (3 shared papers)Silvia H. De Paoli (9 shared papers)Jan Janota (9 shared papers)Anil K. Patri (1 shared paper)
Journals: Blood (6 papers)Transfusion (5 papers)Transfusion Medicine Reviews (3 papers)Toxicon (2 papers)Cellular and Molecular Life Sciences (2 papers)
Partner nations: United States Czechia Bangladesh

In The Last Decade

Jan Šimák

53 papers receiving 1.8k citations

Peers

Countries citing papers authored by Jan Šimák

Since Specialization

Citations

This map shows the geographic impact of Jan Šimák's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Šimák with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Šimák more than expected).

Fields of papers citing papers by Jan Šimák

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Šimák. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Šimák. The network helps show where Jan Šimák may publish in the future.

Co-authors

The 25 scholars most cited alongside Jan Šimák, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jan Šimák Line = papers co-authored together Jan Šimák links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 55 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Cell Membrane Microparticles in Blood and Blood Products: Potentially Pathogenic Agents and Diagnostic Markers Transfusion Medicine Reviews ·Jan Šimák, Monique P. Gelderman	2005	250
2	Nanoparticle Size and Surface Charge Determine Effects of PAMAM Dendrimers on Human Platelets in Vitro Molecular Pharmaceutics ·Marina A. Dobrovolskaia, Anil K. Patri, Jan Šimák, Jennifer B. Hall, Jana Šemberová, Silvia H. De Paoli Lacerda, Scott E. McNeil	2011	185
3	Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria British Journal of Haematology ·Jan Šimák, Karel Holada, Antonio M. Risitano, (unknown), Neal S. Young, Jaroslav G. Vostal	2004	107
4	Subvisible Particle Content, Formulation, and Dose of an Erythropoietin Peptide Mimetic Product Are Associated With Severe Adverse Postmarketing Events Journal of Pharmaceutical Sciences ·Joseph A. Kotarek, Christine Stuart, Silvia H. De Paoli, Jan Šimák, Tsai-Lien Lin, Yamei Gao, Mikhail V. Ovanesov, Yideng Liang, Dorothy E. Scott, Janice Brown, Yun Bai, Dean D. Metcalfe, Ewa Marszal, Jack A. Ragheb	2016	92
5	Carbon Nanotubes Activate Blood Platelets by Inducing Extracellular Ca²⁺ Influx Sensitive to Calcium Entry Inhibitors Nano Letters ·Jana Šemberová, Silvia H. De Paoli Lacerda, Olga Šimáková, Karel Holada, Monique P. Gelderman, Jan Šimák	2009	87
6	The effect of protein corona composition on the interaction of carbon nanotubes with human blood platelets Biomaterials ·Silvia H. De Paoli, Lukas Diduch, Tseday Z. Tegegn, Martina Orečná, Michael Brad Strader, Elena Karnaukhova, John E. Bonevich, Karel Holada, Jan Šimák	2014	82
7	Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin BMC Cell Biology ·Jan Šimák, Karel Holada, Jaroslav G. Vostal	2002	76
8	Flow Cytometric Analysis of Cell Membrane Microparticles Methods in molecular biology ·Monique P. Gelderman, Jan Šimák	2008	73
9	Toxicity of carboxylated carbon nanotubes in endothelial cells is attenuated by stimulation of the autophagic flux with the release of nanomaterial in autophagic vesicles Nanomedicine Nanotechnology Biology and Medicine ·Martina Orečná, Silvia H. De Paoli, Olga Janoušková, Tseday Z. Tegegn, Marcela Filipová, John E. Bonevich, Karel Holada, Jan Šimák	2014	62
10	Carbon Nanotubes Activate Store-Operated Calcium Entry in Human Blood Platelets ACS Nano ·Silvia H. De Paoli Lacerda, Jana Šemberová, Karel Holada, Olga Šimáková, Steven D. Hudson, Jan Šimák	2011	58
11	Cellular prion protein is expressed on endothelial cells and is released during apoptosis on membrane microparticles found in human plasma Transfusion ·Jan Šimák, Karel Holada, Felice D’Agnillo, Jan Janota, Jaroslav G. Vostal	2002	53
12	Hemoglobin oxidation–dependent reactions promote interactions with band 3 and oxidative changes in sickle cell–derived microparticles JCI Insight ·Sirsendu Jana, Michael Brad Strader, Fantao Meng, Wayne Hicks, Tigist Kassa, Ivan D. Tarandovskiy, Silvia De Paoli, Jan Šimák, Michael R. Heaven, John D. Belcher, Gregory M. Vercellotti, Abdu I. Alayash	2018	50
13	First Demonstration of Transmissible Spongiform Encephalopathy-associated Prion Protein (PrPTSE) in Extracellular Vesicles from Plasma of Mice Infected with Mouse-adapted Variant Creutzfeldt-Jakob Disease by in Vitro Amplification Journal of Biological Chemistry ·Paula Saá, Oksana Yakovleva, Jorge de Castro, I. А. Vаsilyevа, Silvia H. De Paoli, Jan Šimák, Larisa Červen̆áková	2014	49
14	Meeting report on protein particles and immunogenicity of therapeutic proteins: Filling in the gaps in risk evaluation and mitigation Biologicals ·John Carpenter, Barry Cherney, Anthony Lubinecki, Stacey Ma, Ewa Marszal, Anthony R. Mire‐Sluis, Thomas J. Nikolai, Jeanne M. Novak, Jack A. Ragheb, Jan Šimák	2010	49
15	Postnatal increase of procalcitonin in premature newborns is enhanced by chorioamnionitis and neonatal sepsis European Journal of Clinical Investigation ·Jan Janota, Zbyněk Straňák, Simona Bělohlávková, Katalin Mudra, Jan Šimák	2001	49
16	Adverse effects of fullerenes on endothelial cells: Fullerenol C60(OH)24 induced tissue factor and ICAM-1 membrane expression and apoptosis in vitro International Journal of Nanomedicine ·Jan Šimák	2008	49
17	Characterization of procoagulant extracellular vesicles and platelet membrane disintegration in DMSO‐cryopreserved platelets Journal of Extracellular Vesicles ·Tseday Z. Tegegn, Silvia H. De Paoli, Martina Orečná, Oumsalama K. Elhelu, Samuel A. Woodle, Ivan D. Tarandovskiy, Mikhail V. Ovanesov, Jan Šimák	2016	45
18	The effects of nanomaterials on blood coagulation in hemostasis and thrombosis Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology ·Jan Šimák, Silvia De Paoli	2017	44
19	Dissecting the biochemical architecture and morphological release pathways of the human platelet extracellular vesiculome Cellular and Molecular Life Sciences ·Silvia H. De Paoli, Tseday Z. Tegegn, Oumsalama K. Elhelu, Michael Brad Strader, Mehulkumar Patel, Lukas Diduch, Ivan D. Tarandovskiy, Yong Wu, Jiwen Zheng, Mikhail V. Ovanesov, Abdu I. Alayash, Jan Šimák	2018	37
20	Fenfluramine-induced pulmonary vasoconstriction: role of serotonin receptors and potassium channels Journal of Applied Physiology ·Simona Bělohlávková, Jan Šimák, Alena Kokešová, Olga Hniličková, Václav Hampl	2001	29

About Jan Šimák

Jan Šimák is a scholar working on Molecular Biology, Hematology, Pulmonary and Respiratory Medicine, Immunology and Genetics, having authored 55 papers that have together received 1.8k indexed citations. Recurring topics across this work include Prion Diseases and Protein Misfolding (12 papers), Platelet Disorders and Treatments (11 papers), Extracellular vesicles in disease (7 papers), Neonatal Respiratory Health Research (6 papers), Graphene and Nanomaterials Applications (5 papers), Blood Coagulation and Thrombosis Mechanisms (4 papers), Complement system in diseases (4 papers) and Neuroscience of respiration and sleep (4 papers). The work is most often cited by research in Hematology (337 citations), Biomaterials (205 citations), Biochemistry (80 citations), Molecular Biology (911 citations) and Immunology (250 citations). Jan Šimák has collaborated with scholars based in United States, Czechia and Bangladesh. Frequent co-authors include Monique P. Gelderman, Karel Holada, Jaroslav G. Vostal, Jana Šemberová, Silvia H. De Paoli Lacerda, Silvia H. De Paoli, Jan Janota, Anil K. Patri, Marina A. Dobrovolskaia and Jennifer B. Hall. Their work appears in journals such as Blood, Transfusion, Transfusion Medicine Reviews, Toxicon and Cellular and Molecular Life Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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