Jan Kehler

1.4k total citations
69 papers, 1.1k citations indexed

About

Jan Kehler is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Jan Kehler has authored 69 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Molecular Biology, 37 papers in Organic Chemistry and 16 papers in Pharmacology. Recurrent topics in Jan Kehler's work include Phosphodiesterase function and regulation (18 papers), Cholinesterase and Neurodegenerative Diseases (14 papers) and Receptor Mechanisms and Signaling (11 papers). Jan Kehler is often cited by papers focused on Phosphodiesterase function and regulation (18 papers), Cholinesterase and Neurodegenerative Diseases (14 papers) and Receptor Mechanisms and Signaling (11 papers). Jan Kehler collaborates with scholars based in Denmark, Italy and United States. Jan Kehler's co-authors include Jacob Nielsen, Anders A. Jensen, Claus T. Christoffersen, Otto Dahl, John Paul Kilburn, Christoffer Bundgaard, Tine B. Stensbøl, Povl Krogsgaard‐Larsen, Morten Langgård and Bente Frølund and has published in prestigious journals such as Nucleic Acids Research, PLoS ONE and Chemical Communications.

In The Last Decade

Jan Kehler

67 papers receiving 1.1k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jan Kehler Denmark 20 690 514 288 250 76 69 1.1k
Carol Smith United States 17 445 0.6× 220 0.4× 118 0.4× 321 1.3× 94 1.2× 20 796
Romano Di Fabio Italy 24 609 0.9× 900 1.8× 132 0.5× 336 1.3× 48 0.6× 104 1.7k
Dianne Kowal United States 21 713 1.0× 347 0.7× 287 1.0× 466 1.9× 12 0.2× 39 1.3k
Joseph H. Krushinski United States 18 382 0.6× 412 0.8× 268 0.9× 313 1.3× 16 0.2× 38 1.2k
Frank E. Blaney United Kingdom 19 1.0k 1.5× 343 0.7× 160 0.6× 720 2.9× 34 0.4× 41 1.9k
Ann M. Decker United States 17 422 0.6× 247 0.5× 179 0.6× 465 1.9× 156 2.1× 58 945
Adam Bucki Poland 22 630 0.9× 333 0.6× 397 1.4× 228 0.9× 7 0.1× 65 1.2k
Michael P. Cassidy United States 18 609 0.9× 593 1.2× 456 1.6× 568 2.3× 100 1.3× 27 1.6k
Peter C. Meltzer United States 24 547 0.8× 470 0.9× 131 0.5× 853 3.4× 139 1.8× 61 1.8k
Lawrence S. Melvin United States 17 322 0.5× 357 0.7× 812 2.8× 555 2.2× 57 0.8× 28 1.4k

Countries citing papers authored by Jan Kehler

Since Specialization
Citations

This map shows the geographic impact of Jan Kehler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Kehler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Kehler more than expected).

Fields of papers citing papers by Jan Kehler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Kehler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Kehler. The network helps show where Jan Kehler may publish in the future.

Co-authorship network of co-authors of Jan Kehler

This figure shows the co-authorship network connecting the top 25 collaborators of Jan Kehler. A scholar is included among the top collaborators of Jan Kehler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jan Kehler. Jan Kehler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Nielsen, Jacob, et al.. (2025). The Molecular Mechanism of PDE1 Regulation. Cells. 14(21). 1722–1722.
2.
Nielsen, Jacob, Charlotte Hougaard, Claus T. Christoffersen, et al.. (2019). Phosphodiesterase 1 Bridges Glutamate Inputs with NO- and Dopamine-Induced Cyclic Nucleotide Signals in the Striatum. Cerebral Cortex. 29(12). 5022–5036. 18 indexed citations
3.
Laursen, M.L., Jan Kehler, Claus T. Christoffersen, et al.. (2017). Novel selective PDE type 1 inhibitors cause vasodilatation and lower blood pressure in rats. British Journal of Pharmacology. 174(15). 2563–2575. 28 indexed citations
4.
Kehler, Jan, et al.. (2015). In Vitro and In Vivo Evidence for Active Brain Uptake of the GHB Analog HOCPCA by the Monocarboxylate Transporter Subtype 1. Journal of Pharmacology and Experimental Therapeutics. 354(2). 166–174. 15 indexed citations
5.
Kehler, Jan, John Paul Kilburn, Sergio Estrada, et al.. (2014). Discovery and Development of 11C-Lu AE92686 as a Radioligand for PET Imaging of Phosphodiesterase10A in the Brain. Journal of Nuclear Medicine. 55(9). 1513–1518. 30 indexed citations
6.
Bundgaard, Christoffer, et al.. (2014). Correlating the Metabolic Stability of Psychedelic 5-HT2A Agonists with Anecdotal Reports of Human Oral Bioavailability. Neurochemical Research. 39(10). 2018–2023. 22 indexed citations
7.
Rottländer, Mario, et al.. (2014). From Pan-Reactive KV7 Channel Opener to Subtype Selective Opener/Inhibitor by Addition of a Methyl Group. PLoS ONE. 9(6). e100209–e100209. 10 indexed citations
8.
Kilburn, John Paul, Jan Kehler, Morten Langgård, et al.. (2013). N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors. Bioorganic & Medicinal Chemistry. 21(19). 6053–6062. 25 indexed citations
9.
Kehler, Jan. (2012). Phosphodiesterase 10A inhibitors: a 2009 – 2012 patent update. Expert Opinion on Therapeutic Patents. 23(1). 31–45. 31 indexed citations
10.
Kehler, Jan, Andreas Ritzén, Morten Langgård, et al.. (2011). Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(12). 3738–3742. 46 indexed citations
11.
Itoh, Kanako, Tamaki Ishima, Jan Kehler, & Kenji Hashimoto. (2011). Potentiation of NGF-induced neurite outgrowth in PC12 cells by papaverine: Role played by PLC-γ, IP3 receptors. Brain Research. 1377. 32–40. 19 indexed citations
12.
Jørgensen, Charlotte, Bente Frølund, Jan Kehler, & Anders A. Jensen. (2011). Discovery of Benzamide Analogues as a Novel Class of 5‐HT3 Receptor Agonists. ChemMedChem. 6(4). 725–736. 13 indexed citations
13.
Krogsgaard‐Larsen, Niels, Anders A. Jensen, & Jan Kehler. (2010). Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands. Bioorganic & Medicinal Chemistry Letters. 20(18). 5431–5433. 10 indexed citations
14.
Jørgensen, Charlotte, Hans Bräuner‐Osborne, Birgitte Nielsen, et al.. (2007). Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: Synthesis and pharmacology at glutamate receptors. Bioorganic & Medicinal Chemistry. 15(10). 3524–3538. 11 indexed citations
15.
Jørgensen, Charlotte, Rasmus P. Clausen, Kasper B. Hansen, et al.. (2007). Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid. Organic & Biomolecular Chemistry. 5(3). 463–471. 16 indexed citations
16.
Kehler, Jan, et al.. (2007). Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters. Bioorganic & Medicinal Chemistry Letters. 17(10). 2834–2837. 25 indexed citations
17.
Ebert, Bjarke, Martin Mortensen, Sally A. Thompson, et al.. (2001). Bioisosteric determinants for subtype selectivity of ligands for heteromeric GABAA receptors. Bioorganic & Medicinal Chemistry Letters. 11(12). 1573–1577. 19 indexed citations
18.
Kehler, Jan, et al.. (1999). Piperidinyl-3-phosphinic acids as novel uptake inhibitors of the neurotransmitter γ-aminobutyric acid (GABA). Bioorganic & Medicinal Chemistry Letters. 9(6). 811–814. 10 indexed citations
19.
Kehler, Jan, et al.. (1998). Synthesis and hybridization properties of an acyclic achiral phosphonate DNA analogue. Bioorganic & Medicinal Chemistry. 6(3). 315–322. 13 indexed citations
20.
Kodra, János T., Jan Kehler, & Otto Dahl. (1995). Stability of oligodeoxynucleoside phosphorodithioates and phosphorothioates in aqueous ammonia. Nucleic Acids Research. 23(16). 3349–3350. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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