Jaime Acquaviva

1.3k citations

21 papers · 1.1k indexed · h-index 14

Cancer Research top 10%
Oncology top 10%
- Cytokine Signaling Pathways and Interactions 2
Genetics top 10%
- Glioma Diagnosis and Treatment 3
Molecular Biology top 10%
- Heat shock proteins research 13
- ATP Synthase and ATPases Research 6
- Cancer therapeutics and mechanisms 3
- PI3K/AKT/mTOR signaling in cancer 3
Pulmonary and Respiratory Medicine top 10%
Computational Theory and Mathematics
- Computational Drug Discovery Methods 3
Immunology
- Toxin Mechanisms and Immunotoxins 3

Co-authors: Al Charest David A. Proia Jim Sang Donald L. Smith Chaohua Zhang Suqin He Manuel Sequeira Ricky Ngok‐Shun Wong
Cited by: Cancer Research Oncology Genetics
Journals: Clinical Cancer Research (3 papers)Molecular Cancer Therapeutics (3 papers)Molecular Cancer Research (2 papers)
Partner nations: United States United Kingdom

In The Last Decade

Jaime Acquaviva

21 papers receiving 1.0k citations

Peers

Countries citing papers authored by Jaime Acquaviva

Since Specialization

Citations

This map shows the geographic impact of Jaime Acquaviva's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jaime Acquaviva with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jaime Acquaviva more than expected).

Fields of papers citing papers by Jaime Acquaviva

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jaime Acquaviva. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jaime Acquaviva. The network helps show where Jaime Acquaviva may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jaime Acquaviva, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jaime Acquaviva Line = papers co-authored together Jaime Acquaviva links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Consecutive Day HSP90 Inhibitor Administration Improves Efficacy in Murine Models of KIT-Driven Malignancies and Canine Mast Cell Tumors Clinical Cancer Research ·Cheryl A. London,Jaime Acquaviva,Donald L. Smith,Manuel Sequeira,Luisa Shin Ogawa,Heather L. Gardner,G. Camoin,Misty D. Bear,Sandra M. Axiak‐Bechtel,David A. Proia	2018	8
2	HSP90 Inhibitor–SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors Molecular Cancer Therapeutics ·David A. Proia,Donald L. Smith,Junyi Zhang,John-Paul Jimenez,Jim Sang,Luisa Shin Ogawa,Manuel Sequeira,Jaime Acquaviva,Suqin He,Chaohua Zhang,Vladimir Khazak,Igor Astsaturov,Takayo Inoue,Noriaki Tatsuta,Sami Osman,Richard C. Bates,Dinesh Chimmanamada,Weiwen Ying	2015	29
3	FGFR3 Translocations in Bladder Cancer: Differential Sensitivity to HSP90 Inhibition Based on Drug Metabolism Molecular Cancer Research ·Jaime Acquaviva,Suqin He,Chaohua Zhang,John-Paul Jimenez,Masazumi Nagai,Jim Sang,Manuel Sequeira,Donald L. Smith,Luisa Shin Ogawa,Takayo Inoue,Noriaki Tatsuta,Margaret A. Knowles,Richard C. Bates,David A. Proia	2014	57
4	mTOR Inhibition Potentiates HSP90 Inhibitor Activity via Cessation of HSP Synthesis Molecular Cancer Research ·Jaime Acquaviva,Suqin He,Jim Sang,Donald L. Smith,Manuel Sequeira,Chaohua Zhang,Richard C. Bates,David A. Proia	2014	40
5	Overcoming Acquired BRAF Inhibitor Resistance in Melanoma via Targeted Inhibition of Hsp90 with Ganetespib Molecular Cancer Therapeutics ·Jaime Acquaviva,Donald L. Smith,John-Paul Jimenez,Chaohua Zhang,Manuel Sequeira,Suqin He,Jim Sang,Richard C. Bates,David A. Proia	2014	79
6	The HSP90 inhibitor ganetespib potentiates the antitumor activity of EGFR tyrosine kinase inhibition in mutant and wild-type non-small cell lung cancer Targeted Oncology ·Donald L. Smith,Jaime Acquaviva,Manuel Sequeira,John-Paul Jimenez,Chaohua Zhang,Jim Sang,Richard C. Bates,David A. Proia	2014	31
7	585 The investigational HSP90 inhibitor ganetespib displays robust single agent activity in gastric cancer models both as monotherapy and in combination with standard of care therapeutics European Journal of Cancer ·Song He,Adrián A. Negreros-Osuna,John-Paul Jimenez,正貴四宮,Manuel Sequeira,Jon Ostrowsky,Jaime Acquaviva,Masazumi Nagai,Richard C. Bates,David A. Proia	2014	1
8	Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer Clinical Cancer Research ·David A. Proia,Chaohua Zhang,Manuel Sequeira,John-Paul Jimenez,Suqin He,Neil L. Spector,Geoffrey I. Shapiro,Sara M. Tolaney,Masazumi Nagai,Jaime Acquaviva,Donald L. Smith,Jim Sang,Richard C. Bates,Iman El‐Hariry	2013	53
9	Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non–Small Cell Lung Cancer Cancer Discovery ·Jim Sang,Jaime Acquaviva,Julie C. Friedland,Donald L. Smith,Manuel Sequeira,Chaohua Zhang,Qin Jiang,Liquan Xue,Christine M. Lovly,Laura Aillaud,Alice T. Shaw,Robert C. Doebele,Suqin He,Richard C. Bates,D. Ross Camidge,Stephan W. Morris,Iman El‐Hariry,David A. Proia	2013	174
10	Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes Investigational New Drugs ·Julie C. Friedland,Donald L. Smith,Jim Sang,Jaime Acquaviva,Suqin He,Chaohua Zhang,David A. Proia	2013	46
11	Abstract 1038: Inhibition of mTOR enhances the activity of HSP90 inhibitors in part through cessation of heat shock protein synthesis. Cancer Research ·Suqin He,Jaime Acquaviva,Julie C. Friedland,Jim Sang,Donald L. Smith,Manuel Sequeira,Chaohua Zhang,David A. Proia	2013	1
12	Targeting KRAS-Mutant Non–Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib Molecular Cancer Therapeutics ·Jaime Acquaviva,Donald L. Smith,Jim Sang,Julie C. Friedland,Suqin He,Manuel Sequeira,Chaohua Zhang,Yumiko Wada,David A. Proia	2012	83
13	Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression International Journal of Oncology ·Suqin He,Chaohua Zhang,Ayesha A. Shafi,Manuel Sequeira,Jaime Acquaviva,Julie C. Friedland,Jim Sang,Donald L. Smith,Nancy L. Weigel,Yumiko Wada,David A. Proia	2012	50
14	Preclinical activity of the Hsp90 inhibitor, ganetespib, in ALK- and ROS1-driven cancers. Journal of Clinical Oncology ·David A. Proia,Jaime Acquaviva,Qin Jiang,Liquan Xue,Donald L. Smith,Julie C. Friedland,Suqin He,Jim Sang,Stephan W. Morris,Yumiko Wada	2012	3
15	Abstract B1: Targeting KRAS mutant NSCLC with the Hsp90 inhibitor ganetespib Clinical Cancer Research ·Jaime Acquaviva,G. Strevelar,Jim Sang,Yumiko Wada,David A. Proia	2012	1
16	Chronic Activation of Wild-Type Epidermal Growth Factor Receptor and Loss of Cdkn2a Cause Mouse Glioblastoma Formation Cancer Research ·Jaime Acquaviva,Blaise Kelly,Julie Lessard,Natalia Reyes Ríos,Huijun Zhu,Michael Donovan,Steve Woolfenden,Abraham Boskovitz,Ami P. Raval,Rod T. Bronson,Rolf Pfannl,Charles A. Whittaker,David E. Housman,Alain Charest	2011	1
17	Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme Oncogene ·Hyun Jung Jun,Jaime Acquaviva,Infante Toro,Julie Lessard,Haihao Zhu,Steve Woolfenden,Roderick T. Bronson,Rolf Pfannl,(unknown),(unknown),Lakshmanan K. Iyer,(unknown),(unknown),Ami P. Raval,Alain Charest	2011	8
18	Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis Blood ·Indah Karunia Fitri,Jonathan H. Schatz,Jaime Acquaviva,Harinder Singh,Ruibao Ren	2010	26
19	Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis Proceedings of the National Academy of Sciences ·Haihao Zhu,Jaime Acquaviva,V P Romenskiĭ,Abraham Boskovitz,Steve Woolfenden,Rolf Pfannl,Roderick T. Bronson,John W. Chen,Ralph Weissleder,David E. Housman,Al Charest	2009	172
20	The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer Biochimica et Biophysica Acta (BBA) - Reviews on Cancer ·Jaime Acquaviva,Ricky Ngok‐Shun Wong,Al Charest	2008	151

About Jaime Acquaviva

Jaime Acquaviva is a scholar working on Genetics, Molecular Biology and Computational Theory and Mathematics, having authored 21 papers that have together received 1.1k indexed citations. Recurring topics across this work include Heat shock proteins research (13 papers), ATP Synthase and ATPases Research (6 papers), Cancer therapeutics and mechanisms (3 papers), Computational Drug Discovery Methods (3 papers), Glioma Diagnosis and Treatment (3 papers), PI3K/AKT/mTOR signaling in cancer (3 papers), Toxin Mechanisms and Immunotoxins (3 papers) and Cytokine Signaling Pathways and Interactions (2 papers). The work is most often cited by research in Cancer Research (184 citations), Oncology (327 citations) and Genetics (123 citations). Jaime Acquaviva has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include Al Charest, David A. Proia, Jim Sang, Donald L. Smith, Chaohua Zhang, Suqin He, Manuel Sequeira, Ricky Ngok‐Shun Wong, Richard C. Bates and Julie C. Friedland. Their work appears in journals such as Clinical Cancer Research, Molecular Cancer Therapeutics, Molecular Cancer Research, Blood and Cancer Research.

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