Isaac S. Chan

2.2k total citations
35 papers, 1.4k citations indexed

About

Isaac S. Chan is a scholar working on Oncology, Molecular Biology and Genetics. According to data from OpenAlex, Isaac S. Chan has authored 35 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Oncology, 11 papers in Molecular Biology and 7 papers in Genetics. Recurrent topics in Isaac S. Chan's work include Hedgehog Signaling Pathway Studies (6 papers), Liver physiology and pathology (4 papers) and Cancer Cells and Metastasis (4 papers). Isaac S. Chan is often cited by papers focused on Hedgehog Signaling Pathway Studies (6 papers), Liver physiology and pathology (4 papers) and Cancer Cells and Metastasis (4 papers). Isaac S. Chan collaborates with scholars based in United States, United Kingdom and Brazil. Isaac S. Chan's co-authors include Geoffrey S. Ginsburg, Anna Mae Diehl, Steve S. Choi, Gamze Karaca, Gregory A. Michelotti, Guanhua Xie, Marzena Swiderska, Wing‐Kin Syn, Cynthia D. Guy and Cynthia A. Moylan and has published in prestigious journals such as Journal of Clinical Investigation, Nature Communications and Journal of Clinical Oncology.

In The Last Decade

Isaac S. Chan

34 papers receiving 1.4k citations

Peers

Countries citing papers authored by Isaac S. Chan

Since Specialization

Citations

This map shows the geographic impact of Isaac S. Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isaac S. Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isaac S. Chan more than expected).

Fields of papers citing papers by Isaac S. Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isaac S. Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isaac S. Chan. The network helps show where Isaac S. Chan may publish in the future.

Co-authorship network of co-authors of Isaac S. Chan

This figure shows the co-authorship network connecting the top 25 collaborators of Isaac S. Chan. A scholar is included among the top collaborators of Isaac S. Chan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isaac S. Chan. Isaac S. Chan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Digital droplet PCR analysis of organoids generated from mouse mammary tumors demonstrates proof-of-concept capture of tumor heterogeneity 2024 ·Frontiers in Cell and Developmental Biology ·(unknown), (unknown), Clayton Smith, (unknown), (unknown), (unknown), (unknown), Heather L. McArthur, Sangeetha M. Reddy, Evanthia T. Roussos Torres, Elizabeth H. Chen, Isaac S. Chan	1
2	A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response 2024 ·Cell Reports Medicine ·(unknown), (unknown), (unknown), Hildur Knútsdóttir, (unknown), (unknown), Kenian Chen, (unknown), Julia Maués, (unknown), Sangeetha M. Reddy, Evanthia T. Roussos Torres, Lin Xu, Isaac S. Chan	24
3	Evaluation of markers of immunity in different metastatic immune microenvironments suggests more suppression within breast to liver metastases in breast cancer 2024 ·Breast Cancer Research and Treatment ·(unknown), (unknown), Daniel Flores, (unknown), (unknown), (unknown), (unknown), Joanne Xiu, Irene Kang, Darcy Spicer, Heinz Josef Lenz, Lily Dara, Foluso O. Ademuyiwa, W. Michael Korn, Sheeba Irshad, Isaac S. Chan, Evanthia T. Roussos Torres	3
4	Identifying mutations in ctDNA to predict antibody-drug conjugate response in breast cancer. 2024 ·Journal of Clinical Oncology ·(unknown), Isaac S. Chan, (unknown)	0
5	Abstract PO4-14-10: Circulating Tumor DNA as a Biomarker for ADCs in Metastatic Breast Cancer 2024 ·Cancer Research ·(unknown), (unknown), (unknown), (unknown), Julia Maués, (unknown), Isaac S. Chan	2
6	Improving the odds together: a framework for breast cancer research scientists to include patient advocates in their research 2022 ·npj Breast Cancer ·(unknown), Igor Bado, (unknown), Martha Carlson, Isaac S. Chan, Gloria V. Echeverria, Andrew J. Ewald, Bora Lim, Carla Lloyd, Julia Maués, Steffi Oesterreich, (unknown), (unknown), Alana L. Welm, (unknown)	2
7	Increasing the field-of-view in oblique plane microscopy via optical tiling 2022 ·Biomedical Optics Express ·Bingying Chen, Bo-Jui Chang, Felix Zhou, Stephan Daetwyler, Etai Sapoznik, Benjamin A. Nanes, (unknown), (unknown), (unknown), Isaac S. Chan, Maralice Conacci‐Sorrell, Kevin M. Dean, Alfred Millett-Sikking, Andrew G. York, Reto Fiolka	10
8	Organoid Co-culture Methods to Capture Cancer Cell–Natural Killer Cell Interactions 2022 ·Methods in molecular biology ·Isaac S. Chan, Andrew J. Ewald	22
9	Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level 2021 ·Nature Communications ·(unknown), (unknown), Nathan M. Livingston, Ariel Gershman, (unknown), Isaac S. Chan, Andrew J. Ewald, Winston Timp, Bin Wu, Abhyudai Singh, Sergi Regot	17
10	Olaparib Use in Patients With Metastatic Breast Cancer Harboring Somatic BRCA1/2 Mutations or Mutations in Non-BRCA1/2, DNA Damage Repair Genes 2021 ·Clinical Breast Cancer ·Elaine M. Walsh, (unknown), John H. Fetting, Deborah K. Armstrong, Isaac S. Chan, Roisín M. Connolly, (unknown), (unknown), Raquel Nunes, (unknown), (unknown), Mirat Shah, Karen L. Smith, Kala Visvanathan, Josh Lauring, Ben Ho Park, Vered Stearns, Antonio C. Wolff	8
11	Cancer cells educate natural killer cells to a metastasis-promoting cell state 2020 ·The Journal of Cell Biology ·Isaac S. Chan, Hildur Knútsdóttir, (unknown), Veena Padmanaban, (unknown), Juan Carlos Ramı́rez, Matthew Dunworth, Hao Zhang, Elizabeth M. Jaffee, Joel S. Bader, Andrew J. Ewald	104
12	Academic Integrity and Ethics: The Influence of Culture and Prior Academic Background 2018 ·Journal on excellence in college teaching ·Theresa Kwong, (unknown), (unknown), Isaac S. Chan	2
13	An Acquired Factor X Inhibitor: The Importance of Understanding Coagulation 2017 ·The American Journal of Medicine ·Isaac S. Chan, (unknown)	4
14	Delayed Diagnosis of Disseminated Cryptococcosis with Associated Meningoencephalitis in an Immunocompetent Septuagenarian Host 2016 ·The American Journal of Medicine ·Isaac S. Chan, (unknown), Adam B. Burrows	2
15	Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma 2012 ·Cancer Research ·Isaac S. Chan, Cynthia D. Guy, Yuping Chen, Jiuyi Lü, Marzena Swiderska‐Syn, Gregory A. Michelotti, Gamze Karaca, Guanhua Xie, Leandi Krüger, Wing‐Kin Syn, (unknown), Thiago A. Pereira, Steve S. Choi, Albert S. Baldwin, Anna Mae Diehl	41
16	Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation 2012 ·Gut ·Guanhua Xie, Steve S. Choi, Wing‐Kin Syn, Gregory A. Michelotti, Marzena Swiderska, Gamze Karaca, Isaac S. Chan, Yuping Chen, Anna Mae Diehl	103
17	Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism 2012 ·Gastroenterology ·Yuping Chen, Steve S. Choi, Gregory A. Michelotti, Isaac S. Chan, Marzena Swiderska‐Syn, Gamze Karaca, Guanhua Xie, Cynthia A. Moylan, Francesca Garibaldi, Richard T. Premont, Hagir B. Suliman, Claude A. Piantadosi, Anna Mae Diehl	222
18	NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease 2012 ·Gut ·Wing‐Kin Syn, Kolade M. Agboola, Marzena Swiderska, Gregory A. Michelotti, Evaggelia Liaskou, Herbert Pang, Guanhua Xie, George Philips, Isaac S. Chan, Gamze Karaca, Thiago A. Pereira, Yuping Chen, Zhiyong Mi, Paul C. Kuo, Steve S. Choi, Cynthia D. Guy, Manal F. Abdelmalek, Anna Mae Diehl	221
19	Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer 2011 ·PLoS ONE ·George Philips, Isaac S. Chan, Marzena Swiderska, (unknown), Cynthia D. Guy, Gamze Karaca, Cynthia A. Moylan, Talaignair N. Venkatraman, Sebastian Feuerlein, Wing‐Kin Syn, Youngmi Jung, Rafal P. Witek, Steve S. Choi, Gregory A. Michelotti, Fatima Rangwala, Elmar M. Merkle, Christopher D. Lascola, Anna Mae Diehl	140
20	Progression elevated gene‐3 promoter (PEG‐Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase^old‐35)‐mediated growth suppression 2007 ·Journal of Cellular Physiology ·Isaac S. Chan, Irina V. Lebedeva, Zao-zhong Su, Devanand Sarkar, Kristoffer Valerie, Paul B. Fisher	11

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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