Isaac N. Pessah

23.7k total citations · 3 hit papers
263 papers, 16.6k citations indexed

About

Isaac N. Pessah is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Isaac N. Pessah has authored 263 papers receiving a total of 16.6k indexed citations (citations by other indexed papers that have themselves been cited), including 167 papers in Molecular Biology, 90 papers in Cellular and Molecular Neuroscience and 52 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Isaac N. Pessah's work include Ion channel regulation and function (125 papers), Neuroscience and Neuropharmacology Research (59 papers) and Cardiac electrophysiology and arrhythmias (46 papers). Isaac N. Pessah is often cited by papers focused on Ion channel regulation and function (125 papers), Neuroscience and Neuropharmacology Research (59 papers) and Cardiac electrophysiology and arrhythmias (46 papers). Isaac N. Pessah collaborates with scholars based in United States, China and France. Isaac N. Pessah's co-authors include Irva Hertz‐Picciotto, Paul D. Allen, Robin Hansen, Paul Ashwood, Paula Krakowiak, Wei Feng, Judy Van de Water, John E. Casida, Pamela J. Lein and Tadeusz F. Molinski and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and JAMA.

In The Last Decade

Isaac N. Pessah

261 papers receiving 16.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome

2010 705 citations Paul Ashwood, Paula Krakowiak et al. profile →
Functional interaction between InsP3 receptors and store-operated Htrp3 channels

1998 546 citations Isaac N. Pessah et al. profile →
Xestospongins: Potent Membrane Permeable Blockers of the Inositol 1,4,5-Trisphosphate Receptor

1997 525 citations Tadeusz F. Molinski, Isaac N. Pessah et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Isaac N. Pessah United States	72	8.2k	3.7k	3.1k	2.9k	2.6k	263	16.6k
Matthias A. Hediger United States	90	14.8k 1.8×	5.9k 1.6×	423 0.1×	2.1k 0.7×	394 0.1×	256	33.5k
Akira Sawa United States	73	10.8k 1.3×	5.2k 1.4×	2.2k 0.7×	2.5k 0.9×	986 0.4×	325	20.4k
Frank R. Sharp United States	87	12.3k 1.5×	7.3k 2.0×	2.3k 0.7×	1.5k 0.5×	565 0.2×	376	27.7k
Michael Spedding France	65	11.7k 1.4×	8.4k 2.3×	1.6k 0.5×	1.2k 0.4×	2.0k 0.8×	231	24.4k
Dennis W. Choi United States	83	15.6k 1.9×	17.7k 4.7×	1.5k 0.5×	748 0.3×	731 0.3×	206	35.4k
Osamu Hayaishi Japan	98	13.6k 1.6×	3.3k 0.9×	3.4k 1.1×	2.1k 0.7×	468 0.2×	531	30.5k
Frederick Naftolin United States	85	4.1k 0.5×	3.0k 0.8×	875 0.3×	7.5k 2.6×	887 0.3×	507	24.8k
Günther Schütz Germany	92	19.6k 2.4×	7.9k 2.1×	2.0k 0.6×	10.4k 3.6×	804 0.3×	261	38.9k
Helgi B. Schiöth Sweden	69	6.6k 0.8×	3.2k 0.9×	2.2k 0.7×	804 0.3×	467 0.2×	443	19.9k
Tamás L. Horváth United States	97	8.2k 1.0×	4.2k 1.1×	4.4k 1.4×	2.3k 0.8×	830 0.3×	328	34.7k

Countries citing papers authored by Isaac N. Pessah

Since Specialization

Citations

This map shows the geographic impact of Isaac N. Pessah's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isaac N. Pessah with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isaac N. Pessah more than expected).

Fields of papers citing papers by Isaac N. Pessah

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isaac N. Pessah. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isaac N. Pessah. The network helps show where Isaac N. Pessah may publish in the future.

Co-authorship network of co-authors of Isaac N. Pessah

This figure shows the co-authorship network connecting the top 25 collaborators of Isaac N. Pessah. A scholar is included among the top collaborators of Isaac N. Pessah based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isaac N. Pessah. Isaac N. Pessah is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Liu, Xiuzhen, et al.. (2024). The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics. 12(4). 263–263. 1 indexed citations

Pessah, Isaac N., et al.. (2023). Investigations into hydrogen sulfide-induced suppression of neuronal activity in vivo and calcium dysregulation in vitro. Toxicological Sciences. 192(2). 247–264. 10 indexed citations

Singh, Vikrant, et al.. (2022). The seizure‐inducing plastic explosive RDX inhibits the α1β2γ2 GABA_A receptor. Annals of Clinical and Translational Neurology. 9(5). 600–609. 3 indexed citations

Wulff, Heike, et al.. (2021). Structure-Activity Relationship of Neuroactive Steroids, Midazolam, and Perampanel Toward Mitigating Tetramine-Triggered Activity in Murine Hippocampal Neuronal Networks. Toxicological Sciences. 180(2). 325–341. 5 indexed citations

Zheng, Jing, et al.. (2021). Marine and Anthropogenic Bromopyrroles Alter Cellular Ca²⁺ Dynamics of Murine Cortical Neuronal Networks by Targeting the Ryanodine Receptor and Sarco/Endoplasmic Reticulum Ca²⁺-ATPase. Environmental Science & Technology. 55(23). 16023–16033. 3 indexed citations

Feng, Wei, et al.. (2020). Ryanodine Receptor Type 2: A Molecular Target for Dichlorodiphenyltrichloroethane- and Dichlorodiphenyldichloroethylene-Mediated Cardiotoxicity. Toxicological Sciences. 178(1). 159–172. 13 indexed citations

Pessah, Isaac N., Pamela J. Lein, Richard F. Seegal, & Sharon K. Sagiv. (2019). Neurotoxicity of polychlorinated biphenyls and related organohalogens. Acta Neuropathologica. 138(3). 363–387. 143 indexed citations

Li, Xueshu, Erika B. Holland, Wei Feng, et al.. (2018). Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environmental Science and Pollution Research. 25(17). 16508–16521. 29 indexed citations

Zheng, Jing, Juan Chen, Xiaohan Zou, et al.. (2018). Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. NeuroToxicology. 70. 112–121. 21 indexed citations

10.

Zheng, Jing, Shaun M. K. McKinnie, Wei Feng, et al.. (2018). Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca²⁺Dynamics. Environmental Science & Technology. 52(9). 5469–5478. 17 indexed citations

11.

Cao, Zhengyu, Susan Hulsizer, Yanjun Cui, et al.. (2013). Enhanced Asynchronous Ca2+ Oscillations Associated with Impaired Glutamate Transport in Cortical Astrocytes Expressing Fmr1 Gene Premutation Expansion. Journal of Biological Chemistry. 288(19). 13831–13841. 38 indexed citations

12.

Girirajan, Santhosh, Rebecca L. Johnson, Flora Tassone, et al.. (2013). Global increases in both common and rare copy number load associated with autism. Human Molecular Genetics. 22(14). 2870–2880. 47 indexed citations

13.

Braunschweig, Daniel, Paula Krakowiak, Robert Boyce, et al.. (2013). Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Translational Psychiatry. 3(7). e277–e277. 191 indexed citations

14.

Liu, Jing, Zhengyu Cao, Susan Hulsizer, et al.. (2012). Signaling defects in iPSC-derived fragile X premutation neurons. Human Molecular Genetics. 21(17). 3795–3805. 102 indexed citations

15.

Eltit, José M., Roger A. Bannister, Ong Moua, et al.. (2012). Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca ²⁺ channel and the type 1 ryanodine receptor. Proceedings of the National Academy of Sciences. 109(20). 7923–7928. 71 indexed citations

16.

Cherednichenko, Gennady, Rui Zhang, Roger A. Bannister, et al.. (2012). Triclosan impairs excitation–contraction coupling and Ca ²⁺ dynamics in striated muscle. Proceedings of the National Academy of Sciences. 109(35). 14158–14163. 138 indexed citations

17.

Woods, Rima, Roxanne O. Vallero, Mari S. Golub, et al.. (2012). Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. Human Molecular Genetics. 21(11). 2399–2411. 79 indexed citations

18.

Bannister, Roger A., Isaac N. Pessah, & Kurt G. Beam. (2008). The Skeletal L-type Ca2+ Current Is a Major Contributor to Excitation-coupled Ca2+ entry. The Journal of General Physiology. 133(1). 79–91. 92 indexed citations

19.

İnceoğlu, Bora, József Langó, Isaac N. Pessah, & Bruce D. Hammock. (2005). Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon. 45(6). 727–733. 20 indexed citations

20.

DiJulio, Dennis H., et al.. (1996). Ryanodine receptor identification in mouse parotid acinar cells. The FASEB Journal. 10(3). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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