Hiroyuki Koide

3.4k total citations · 1 hit paper
64 papers, 2.8k citations indexed

About

Hiroyuki Koide is a scholar working on Molecular Biology, Biomaterials and Immunology. According to data from OpenAlex, Hiroyuki Koide has authored 64 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Molecular Biology, 23 papers in Biomaterials and 7 papers in Immunology. Recurrent topics in Hiroyuki Koide's work include Nanoparticle-Based Drug Delivery (23 papers), RNA Interference and Gene Delivery (22 papers) and Advanced biosensing and bioanalysis techniques (16 papers). Hiroyuki Koide is often cited by papers focused on Nanoparticle-Based Drug Delivery (23 papers), RNA Interference and Gene Delivery (22 papers) and Advanced biosensing and bioanalysis techniques (16 papers). Hiroyuki Koide collaborates with scholars based in Japan, United States and Australia. Hiroyuki Koide's co-authors include Naoto Oku, Tomohiro Asai, Yu Hoshino, Kenneth J. Shea, Sei Yonezawa, Takashi Kodama, Takeo Urakami, Hiroaki Kanazawa, Kosuke Shimizu and Kazumi Kato and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nature Communications.

In The Last Decade

Hiroyuki Koide

61 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Recent advances in siRNA delivery mediated by lipid-based nanoparticles

2020 298 citations Sei Yonezawa, Hiroyuki Koide et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hiroyuki Koide Japan	25	1.3k	644	609	378	237	64	2.8k
Soo‐Jeong Lim South Korea	34	1.3k 1.0×	746 1.2×	394 0.6×	124 0.3×	147 0.6×	88	3.4k
Young Wook Choi South Korea	33	894 0.7×	529 0.8×	324 0.5×	216 0.6×	129 0.5×	133	3.1k
Ajit S. Narang United States	27	1.0k 0.8×	282 0.4×	313 0.5×	255 0.7×	79 0.3×	73	2.9k
Padma V. Devarajan India	31	1.0k 0.8×	929 1.4×	462 0.8×	112 0.3×	120 0.5×	91	3.0k
Yinghua Sun China	34	1.0k 0.8×	570 0.9×	1.6k 2.6×	162 0.4×	224 0.9×	116	4.4k
Thao T.D. Tran Vietnam	30	633 0.5×	674 1.0×	399 0.7×	170 0.4×	80 0.3×	104	2.8k
Maria Immacolata La Rotonda Italy	32	847 0.7×	707 1.1×	532 0.9×	149 0.4×	100 0.4×	72	3.4k
Qianqian Li China	29	1.3k 1.0×	419 0.7×	1.1k 1.7×	120 0.3×	286 1.2×	118	3.0k
Chul Soon Yong South Korea	41	1.4k 1.1×	1.5k 2.3×	1.3k 2.1×	366 1.0×	267 1.1×	108	4.8k
Lifang Fan China	32	1.8k 1.4×	283 0.4×	818 1.3×	144 0.4×	124 0.5×	111	4.0k

Countries citing papers authored by Hiroyuki Koide

Since Specialization

Citations

This map shows the geographic impact of Hiroyuki Koide's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroyuki Koide with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroyuki Koide more than expected).

Fields of papers citing papers by Hiroyuki Koide

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroyuki Koide. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroyuki Koide. The network helps show where Hiroyuki Koide may publish in the future.

Co-authorship network of co-authors of Hiroyuki Koide

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroyuki Koide. A scholar is included among the top collaborators of Hiroyuki Koide based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroyuki Koide. Hiroyuki Koide is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Takahashi, Sayaka, et al.. (2025). Development of a messenger RNA vaccine using pH-responsive dipeptide-conjugated lipids exhibiting reduced inflammatory properties. International Journal of Pharmaceutics. 674. 125485–125485.

Koide, Hiroyuki, Shinya Hirata, Hiroki Ochiai, et al.. (2025). In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy. Journal of Controlled Release. 382. 113734–113734. 1 indexed citations

Koide, Hiroyuki, Kazuhiro Saito, Keiichi Yoshimatsu, et al.. (2023). Cooling-induced, localized release of cytotoxic peptides from engineered polymer nanoparticles in living mice for cancer therapy. Journal of Controlled Release. 355. 745–759. 9 indexed citations

Asai, Tomohiro, Hiroyuki Koide, Ayaka Okamoto, et al.. (2023). Treatment of PTEN-Null Breast Cancer by a Synthetic Lethal Approach Involving PARP1 Gene Silencing. Journal of Pharmaceutical Sciences. 112(7). 1908–1914. 2 indexed citations

Koide, Hiroyuki, Yu Hoshino, Keiichi Yoshimatsu, et al.. (2021). Synthetic hydrogel nanoparticles for sepsis therapy. Nature Communications. 12(1). 5552–5552. 56 indexed citations

Koide, Hiroyuki, Sei Yonezawa, & Tomohiro Asai. (2021). siRNA Vehicles for High Endosomal Escapability. Methods in molecular biology. 2282. 171–179. 1 indexed citations

Koide, Hiroyuki, Yu Hoshino, Hiromichi Egami, et al.. (2021). Design of synthetic polymer nanoparticles that inhibit glucose absorption from the intestine. Biochemical and Biophysical Research Communications. 561. 1–6. 1 indexed citations

Koide, Hiroyuki, Hiroki Ochiai, Hiromichi Egami, et al.. (2021). Enhancement of target toxin neutralization effect in vivo by PEGylation of multifunctionalized lipid nanoparticles. Biochemical and Biophysical Research Communications. 555. 32–39. 11 indexed citations

Furuya, Masahiro, et al.. (2020). Comparison of the Structure and Phase Changes of Carbon-Coated SiO and Li-Doped Carbon-Coated SiO During Repeated Charge–Discharge Cycling. Journal of The Electrochemical Society. 167(12). 120523–120523. 7 indexed citations

10.

Zang, Liqing, Yasuhito Shimada, Hiroko Nakayama, et al.. (2019). Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus. Frontiers in Genetics. 10. 693–693. 5 indexed citations

11.

Okamoto, Ayaka, Hiroyuki Koide, Naoki Morita, et al.. (2018). Rigorous control of vesicle-forming lipid pKa by fluorine-conjugated bioisosteres for gene-silencing with siRNA. Journal of Controlled Release. 295. 87–92. 16 indexed citations

12.

Koide, Hiroyuki, Keiichi Yoshimatsu, Yu Hoshino, et al.. (2017). A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165). Nature Chemistry. 9(7). 715–722. 135 indexed citations

13.

Yoshikawa, Yuko, et al.. (2016). Amelioration of Citrobacter rodentium proliferation in early stage of infection in mice by pre-treatment with Lactobacillus brevis KB290 and verification using in vivo bioluminescence imaging. FEMS Microbiology Letters. 364(6). fnw254–fnw254. 3 indexed citations

14.

Koide, Hiroyuki, Ayaka Okamoto, Hiroki Tsuchida, et al.. (2016). One-step encapsulation of siRNA between lipid-layers of multi-layer polycation liposomes by lipoplex freeze-thawing. Journal of Controlled Release. 228. 1–8. 26 indexed citations

15.

Fukuta, Tatsuya, Tomohiro Asai, Takayuki Ishii, et al.. (2016). Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-I activity. Scientific Reports. 6(1). 30127–30127. 14 indexed citations

16.

Yoshimatsu, Keiichi, Hiroyuki Koide, Yu Hoshino, & Kenneth J. Shea. (2015). Preparation of abiotic polymer nanoparticles for sequestration and neutralization of a target peptide toxin. Nature Protocols. 10(4). 595–604. 47 indexed citations

17.

Koide, Hiroyuki, Tomohiro Asai, Hiroki Kato, et al.. (2014). Susceptibility of PTEN-positive metastatic tumors to small interfering RNA targeting the mammalian target of rapamycin. Nanomedicine Nanotechnology Biology and Medicine. 11(1). 185–194. 14 indexed citations

18.

Ando, Hidenori, Tomohiro Asai, Hiroyuki Koide, et al.. (2014). Advanced cancer therapy by integrative antitumor actions via systemic administration of miR-499. Journal of Controlled Release. 181. 32–39. 36 indexed citations

19.

Asakawa, Tomohiro, Makoto Inai, Hiroyuki Koide, et al.. (2011). PET imaging of nobiletin based on a practical total synthesis. Chemical Communications. 47(10). 2868–2868. 37 indexed citations

20.

Hoshino, Yu, Takeo Urakami, Takashi Kodama, et al.. (2009). Design of Synthetic Polymer Nanoparticles that Capture and Neutralize a Toxic Peptide. Small. 5(13). 1562–1568. 92 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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