Hiroshi Tsushima

2.0k total citations · 1 hit paper
50 papers, 1.6k citations indexed

About

Hiroshi Tsushima is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Hiroshi Tsushima has authored 50 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 13 papers in Oncology and 10 papers in Cancer Research. Recurrent topics in Hiroshi Tsushima's work include Protease and Inhibitor Mechanisms (8 papers), Peptidase Inhibition and Analysis (6 papers) and Cardiovascular Disease and Adiposity (5 papers). Hiroshi Tsushima is often cited by papers focused on Protease and Inhibitor Mechanisms (8 papers), Peptidase Inhibition and Analysis (6 papers) and Cardiovascular Disease and Adiposity (5 papers). Hiroshi Tsushima collaborates with scholars based in Japan, Finland and France. Hiroshi Tsushima's co-authors include Hirofumi Sumi, H Mihara, Hiroki Hamada, H Muraki, Nobuyuki Ito, Satoru Tamura, Yūji Matsuzawa, Shinichi Kiso, Yukihiko Matsuda and Satoshi Kawata and has published in prestigious journals such as Gastroenterology, Hepatology and Biochemical and Biophysical Research Communications.

In The Last Decade

Hiroshi Tsushima

45 papers receiving 1.5k citations

Hit Papers

A novel fibrinolytic enzyme (nattokinase) in the vegetabl... 1987 2026 2000 2013 1987 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet
    1987 466 citations Hirofumi Sumi, Hiroki Hamada et al. Cellular and Molecular Life Sciences profile →

Peers

Hiroshi Tsushima
Tomohiro Mizutani Japan
Naoki Watanabe Japan
B. Van Hoef Belgium
Atsushi Kondo Japan
Shaoxia Zhou Germany
Lili Sun China
Harald Thidemann Johansen Norway
Ko‐Jiunn Liu Taiwan
Hitoshi Kawamata Japan
Bijan Ansari United Kingdom
Tomohiro Mizutani Japan
Hiroshi Tsushima
Citations per year, relative to Hiroshi Tsushima Hiroshi Tsushima (= 1×) peers Tomohiro Mizutani

Countries citing papers authored by Hiroshi Tsushima

Since Specialization
Citations

This map shows the geographic impact of Hiroshi Tsushima's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroshi Tsushima with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroshi Tsushima more than expected).

Fields of papers citing papers by Hiroshi Tsushima

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroshi Tsushima. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroshi Tsushima. The network helps show where Hiroshi Tsushima may publish in the future.

Co-authorship network of co-authors of Hiroshi Tsushima

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroshi Tsushima. A scholar is included among the top collaborators of Hiroshi Tsushima based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroshi Tsushima. Hiroshi Tsushima is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
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Tomita, Hiroyuki, Kunihiro Hayakawa, Keigo Ikeda, et al.. (2025). miR-6516-3p-mediated downregulation of the endogenous MMP-9 inhibitor RECK in mesangial cells might exacerbate lupus nephritis. Molecular Medicine. 31(1). 84–84. 1 indexed citations
3.
Yoshida, Yuko, Kunihiro Hayakawa, Maki Fujishiro, et al.. (2020). Social defeat stress exacerbates atopic dermatitis through downregulation of DNA methyltransferase 1 and upregulation of C–C motif chemokine receptor 7 in skin dendritic cells. Biochemical and Biophysical Research Communications. 529(4). 1073–1079. 15 indexed citations
4.
Hayakawa, Kunihiro, Mikiko Kawasaki, Takuya Hirai, et al.. (2019). MicroRNA-766-3p Contributes to Anti-Inflammatory Responses through the Indirect Inhibition of NF-κB Signaling. International Journal of Molecular Sciences. 20(4). 809–809. 41 indexed citations
5.
Ikeda, Keigo, Kunihiro Hayakawa, Maki Fujishiro, et al.. (2017). JAK inhibitor has the amelioration effect in lupus-prone mice: the involvement of IFN signature gene downregulation. BMC Immunology. 18(1). 41–41. 47 indexed citations
6.
7.
Nozawa, Kazuhisa, Takuya Hirai, Hiroshi Tsushima, et al.. (2015). Second-to-fourth Digit Ratio in Systemic Lupus Erythematosus. The Journal of Rheumatology. 42(5). 826–828. 5 indexed citations
8.
Kitagawa, Toshiro, Hideya Yamamoto, Kazuhiro Sentani, et al.. (2015). The relationship between inflammation and neoangiogenesis of epicardial adipose tissue and coronary atherosclerosis based on computed tomography analysis. Atherosclerosis. 243(1). 293–299. 41 indexed citations
9.
Nakano, Souichiro, Shinji Morimoto, Satoshi Suzuki, et al.. (2015). Immunoregulatory role of IL-35 in T cells of patients with rheumatoid arthritis. Lara D. Veeken. 54(8). 1498–1506. 53 indexed citations
10.
Kunita, Eiji, Hideya Yamamoto, Toshiro Kitagawa, et al.. (2014). Prognostic value of coronary artery calcium and epicardial adipose tissue assessed by non-contrast cardiac computed tomography. Atherosclerosis. 233(2). 447–453. 41 indexed citations
11.
Utsunomiya, Hiroto, Hideya Yamamoto, Toshiro Kitagawa, et al.. (2013). Incremental prognostic value of cardiac computed tomography angiography in asymptomatic aortic stenosis: Significance of aortic valve calcium score. International Journal of Cardiology. 168(6). 5205–5211. 22 indexed citations
12.
Yamamoto, Hideya, Toshiro Kitagawa, Norihiko Ohashi, et al.. (2013). Noncalcified atherosclerotic lesions with vulnerable characteristics detected by coronary CT angiography and future coronary events. Journal of cardiovascular computed tomography. 7(3). 192–199. 49 indexed citations
13.
Tsushima, Hiroshi, Satoshi Kawata, Satoru Tamura, et al.. (1996). High levels of transforming growth factor beta 1 in patients with colorectal cancer: Association with disease progression. Gastroenterology. 110(2). 375–382. 237 indexed citations
14.
Yoshii, Akira, Toshiro Kageshita, Hiroshi Tsushima, & Tomomichi Ono. (1995). Clinical relevance of cathepsin B-like enzyme activity and cysteine proteinase inhibitor in melanocytic tumours. Archives of Dermatological Research. 287(2). 209–213. 12 indexed citations
15.
Tsushima, Hiroshi, et al.. (1994). Candida albicans aspartic proteinase cleaves and inactivates human epidermal cysteine proteinase inhibitor, cystatin A. Microbiology. 140(1). 167–171. 24 indexed citations
16.
Tsushima, Hiroshi, et al.. (1992). Purification and characterization of a cystatin-type cysteine proteinase inhibitor in the human hair shaft. Archives of Dermatological Research. 284(7). 380–385. 11 indexed citations
17.
Ueki, A, Masahiro Yamaguchi, Y. Watanabe, et al.. (1992). Activation of human CD4+CD45RA+ T cells by chrysotile asbestos in vitro. Cancer Letters. 66(2). 99–106. 10 indexed citations
18.
Sumi, Hirofumi, et al.. (1991). Activated fibrinolytic enzymes in the synovial fluid during acute arthritis induced by urate crystal injection in dogs. Blood Coagulation & Fibrinolysis. 2(5). 609–616. 8 indexed citations
19.
Tsushima, Hiroshi & V. K. Hopsu‐Havu. (1990). A chloride activated alanine aminopeptidase from a melanoma cell line.. PubMed. 37(4). 415–25. 3 indexed citations
20.
Sumi, Hirofumi, Hiroki Hamada, Hiroshi Tsushima, H Mihara, & H Muraki. (1987). A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. Cellular and Molecular Life Sciences. 43(10). 1110–1111. 466 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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