Hazem E. Ghoneim

3.9k total citations · 3 hit papers
29 papers, 2.6k citations indexed

About

Hazem E. Ghoneim is a scholar working on Immunology, Molecular Biology and Oncology. According to data from OpenAlex, Hazem E. Ghoneim has authored 29 papers receiving a total of 2.6k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Immunology, 10 papers in Molecular Biology and 7 papers in Oncology. Recurrent topics in Hazem E. Ghoneim's work include Immune Cell Function and Interaction (17 papers), T-cell and B-cell Immunology (15 papers) and Epigenetics and DNA Methylation (7 papers). Hazem E. Ghoneim is often cited by papers focused on Immune Cell Function and Interaction (17 papers), T-cell and B-cell Immunology (15 papers) and Epigenetics and DNA Methylation (7 papers). Hazem E. Ghoneim collaborates with scholars based in United States, Australia and Egypt. Hazem E. Ghoneim's co-authors include Paul G. Thomas, Ben Youngblood, Yiping Fan, Jonathan A. McCullers, Pranay Dogra, Hossam A. Abdelsamed, Ardiana Moustaki, Walid Awad, Robert Carter and Pradyot Dash and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Hazem E. Ghoneim

25 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation

2017 567 citations Hazem E. Ghoneim, Yiping Fan et al. Cell profile →
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

2019 546 citations Francesca Alfei, Kristiyan Kanev et al. Nature profile →
Functional T cells are capable of supernumerary cell division and longevity

2023 111 citations Andrew G. Soerens, Marco Künzli et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hazem E. Ghoneim United States	17	1.9k	996	697	519	168	29	2.6k
Klaas P. J. M. van Gisbergen Netherlands	32	2.8k 1.5×	772 0.8×	655 0.9×	372 0.7×	170 1.0×	63	3.5k
Mohamed S. Abdel-Hakeem Egypt	14	1.8k 0.9×	1.3k 1.3×	509 0.7×	368 0.7×	182 1.1×	26	2.6k
Caroline Aspord France	25	1.7k 0.9×	855 0.9×	493 0.7×	302 0.6×	101 0.6×	63	2.4k
Shruti Subramaniam United States	6	3.1k 1.6×	1.4k 1.4×	489 0.7×	461 0.9×	192 1.1×	6	3.7k
Maike Hofmann Germany	25	2.0k 1.0×	1.0k 1.0×	411 0.6×	683 1.3×	308 1.8×	72	2.9k
Mark Cobbold United Kingdom	22	1.6k 0.8×	807 0.8×	535 0.8×	1.4k 2.7×	168 1.0×	58	2.9k
Shawn D. Blackburn United States	12	2.7k 1.4×	1.5k 1.5×	377 0.5×	562 1.1×	250 1.5×	12	3.4k
Dorothée Duluc France	21	1.7k 0.9×	595 0.6×	451 0.6×	222 0.4×	87 0.5×	36	2.2k
Pamela M. Odorizzi United States	18	3.1k 1.6×	2.2k 2.2×	727 1.0×	460 0.9×	178 1.1×	25	4.1k
Alina C. Boesteanu United States	24	3.2k 1.7×	749 0.8×	556 0.8×	270 0.5×	127 0.8×	35	3.9k

Countries citing papers authored by Hazem E. Ghoneim

Since Specialization

Citations

This map shows the geographic impact of Hazem E. Ghoneim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hazem E. Ghoneim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hazem E. Ghoneim more than expected).

Fields of papers citing papers by Hazem E. Ghoneim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hazem E. Ghoneim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hazem E. Ghoneim. The network helps show where Hazem E. Ghoneim may publish in the future.

Co-authorship network of co-authors of Hazem E. Ghoneim

This figure shows the co-authorship network connecting the top 25 collaborators of Hazem E. Ghoneim. A scholar is included among the top collaborators of Hazem E. Ghoneim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hazem E. Ghoneim. Hazem E. Ghoneim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Gong, Qiaoke, Kaitlin A. Read, Jacob S. Yount, et al.. (2025). Aiolos restricts the generation of antigen-inexperienced, virtual memory CD8+ T cells in mice. Nature Communications. 17(1). 839–839.

Pai, Joy A., Bence Dániel, Saravanan Raju, et al.. (2025). The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells. Immunity. 58(10). 2472–2488.e9. 2 indexed citations

Lowin, Ava, et al.. (2025). Faithful modeling of terminal CD8+T cell dysfunction and epigenetic stabilization in vitro. JCI Insight. 10(19).

Soerens, Andrew G., Marco Künzli, Clare F. Quarnstrom, et al.. (2023). Functional T cells are capable of supernumerary cell division and longevity. Nature. 614(7949). 762–766. 111 indexed citations breakdown →

Chen, Yulin, et al.. (2022). Rebalancing TGFβ1/BMP signals in exhausted T cells unlocks responsiveness to immune checkpoint blockade therapy. Nature Immunology. 24(2). 280–294. 24 indexed citations

Chen, Heng-Yi, Eric C. Johnson, Edahí González‐Avalos, et al.. (2022). Epigenetic remodeling by vitamin C potentiates plasma cell differentiation. eLife. 11. 17 indexed citations

Ghoneim, Hazem E., et al.. (2021). T cell exhaustion—a memory locked behind scars. Nature Immunology. 22(8). 938–940. 5 indexed citations

Zebley, Caitlin C., Hossam A. Abdelsamed, Hazem E. Ghoneim, et al.. (2021). Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation. Cell Reports. 37(2). 109796–109796. 27 indexed citations

Read, Kaitlin A., Bharath Sreekumar, Michael D. Powell, et al.. (2021). Eos differentially regulates Th1 versus Tfh differentiation through feed-forward propagation of the IL-2/STAT5 signaling pathway. The Journal of Immunology. 206(1_Supplement). 53.10–53.10. 1 indexed citations

10.

Fonseca, Raíssa, Lalit K. Beura, Clare F. Quarnstrom, et al.. (2020). Developmental plasticity allows outside-in immune responses by resident memory T cells. Nature Immunology. 21(4). 412–421. 187 indexed citations

11.

Zebley, Caitlin C., Hossam A. Abdelsamed, Hazem E. Ghoneim, et al.. (2020). IL-12 Signaling Promotes TET2-Mediated DNA Demethylation During CD8 T Cell Effector Differentiation. SSRN Electronic Journal. 1 indexed citations

12.

Alfei, Francesca, Kristiyan Kanev, Maike Hofmann, et al.. (2019). TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature. 571(7764). 265–269. 546 indexed citations breakdown →

13.

Youngblood, Ben, Hazem E. Ghoneim, Hossam A. Abdelsamed, et al.. (2019). De novo DNA methylation programs regulate T cell exhaustion and limit T cell-based immunotherapies. The Journal of Immunology. 202(1_Supplement). 134.14–134.14. 1 indexed citations

14.

Ghoneim, Hazem E., Yiping Fan, Ardiana Moustaki, et al.. (2017). De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation. Cell. 170(1). 142–157.e19. 567 indexed citations breakdown →

15.

Youngblood, Ben, J. Scott Hale, Haydn Kissick, et al.. (2017). Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature. 552(7685). 404–409. 343 indexed citations

16.

Ghoneim, Hazem E., Anthony E. Zamora, Paul G. Thomas, & Ben Youngblood. (2016). Cell-Intrinsic Barriers of T Cell-Based Immunotherapy. Trends in Molecular Medicine. 22(12). 1000–1011. 49 indexed citations

17.

Youngblood, Ben, Hazem E. Ghoneim, Hossam A. Abdelsamed, et al.. (2016). T cell exhaustion is Reinforced by Progressive De novo DNA Methylation Programming. The Journal of Immunology. 196(1_Supplement). 214.4–214.4. 1 indexed citations

18.

Ghoneim, Hazem E. & J. A. McCullers. (2013). Adjunctive Corticosteroid Therapy Improves Lung Immunopathology and Survival During Severe Secondary Pneumococcal Pneumonia in Mice. The Journal of Infectious Diseases. 209(9). 1459–1468. 35 indexed citations

19.

Aldridge, Jerry R., Susu Duan, Hazem E. Ghoneim, et al.. (2011). Fatal Outcome of Pandemic H1N1 2009 Influenza Virus Infection Is Associated with Immunopathology and Impaired Lung Repair, Not Enhanced Viral Burden, in Pregnant Mice. Journal of Virology. 85(21). 11208–11219. 71 indexed citations

20.

Alymova, Irina V., Amanda Green, Julie McAuley, et al.. (2011). Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82. Journal of Virology. 85(23). 12324–12333. 67 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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