Guanghua Lei

7.9k total citations · 2 hit papers
225 papers, 5.0k citations indexed

About

Guanghua Lei is a scholar working on Rheumatology, Surgery and Molecular Biology. According to data from OpenAlex, Guanghua Lei has authored 225 papers receiving a total of 5.0k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Rheumatology, 85 papers in Surgery and 40 papers in Molecular Biology. Recurrent topics in Guanghua Lei's work include Osteoarthritis Treatment and Mechanisms (75 papers), Knee injuries and reconstruction techniques (32 papers) and Total Knee Arthroplasty Outcomes (30 papers). Guanghua Lei is often cited by papers focused on Osteoarthritis Treatment and Mechanisms (75 papers), Knee injuries and reconstruction techniques (32 papers) and Total Knee Arthroplasty Outcomes (30 papers). Guanghua Lei collaborates with scholars based in China, United States and United Kingdom. Guanghua Lei's co-authors include Chao Zeng, Jie Wei, Shuguang Gao, Wei Luo, Tuo Yang, Yilun Wang, Fangjie Zhang, Yuqing Zhang, Yusheng Li and Hui Li and has published in prestigious journals such as JAMA, Nature Communications and ACS Nano.

In The Last Decade

Guanghua Lei

214 papers receiving 5.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targeted apoptosis of macrophages and osteoclasts in arthritic joints is effective against advanced inflammatory arthritis

2021 195 citations Caifeng Deng, Guanghua Lei et al. profile →
Global burden of early-onset osteoarthritis, 1990–2019: results from the Global Burden of Disease Study 2019

2024 64 citations Yuqing Zhang, Weiya Zhang et al. Annals of the Rheumatic Diseases profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Guanghua Lei China	36	1.7k	1.6k	1.2k	717	595	225	5.0k
Chao Zeng China	40	1.5k 0.9×	1.4k 0.9×	1.2k 1.0×	644 0.9×	695 1.2×	222	5.0k
Jie Wei China	38	1.1k 0.6×	1.1k 0.7×	1.2k 1.0×	411 0.6×	545 0.9×	216	4.5k
Roberta Ramonda Italy	43	4.2k 2.4×	1.2k 0.8×	797 0.7×	754 1.1×	631 1.1×	262	6.0k
Raquel Largo Spain	38	2.2k 1.3×	657 0.4×	1.4k 1.2×	492 0.7×	977 1.6×	130	4.9k
Lidong Wu China	38	1.7k 1.0×	1.1k 0.7×	1.5k 1.3×	265 0.4×	721 1.2×	166	4.9k
Jianhao Lin China	34	1.8k 1.0×	1.5k 1.0×	657 0.6×	648 0.9×	672 1.1×	184	4.3k
Jérémie Sellam France	44	4.3k 2.5×	1.2k 0.8×	1.4k 1.1×	398 0.6×	1.1k 1.8×	201	7.2k
Thomas Stäbler United States	31	1.7k 1.0×	943 0.6×	500 0.4×	357 0.5×	509 0.9×	70	3.2k
Yanyan Zhu United States	28	1.7k 1.0×	1.8k 1.1×	789 0.7×	520 0.7×	267 0.4×	83	4.9k
Daniel Uebelhart Switzerland	40	2.0k 1.2×	941 0.6×	785 0.7×	1.4k 1.9×	1.2k 2.0×	110	6.0k

Countries citing papers authored by Guanghua Lei

Since Specialization

Citations

This map shows the geographic impact of Guanghua Lei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guanghua Lei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guanghua Lei more than expected).

Fields of papers citing papers by Guanghua Lei

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guanghua Lei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guanghua Lei. The network helps show where Guanghua Lei may publish in the future.

Co-authorship network of co-authors of Guanghua Lei

This figure shows the co-authorship network connecting the top 25 collaborators of Guanghua Lei. A scholar is included among the top collaborators of Guanghua Lei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Guanghua Lei. Guanghua Lei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Yilun, Ziying Wu, Yuqing Zhang, et al.. (2025). Bidirectional association of daily steps with sarcopenia: a longitudinal study. Annals of Medicine. 57(1). 2537353–2537353. 1 indexed citations

Deng, Caifeng, Xuan Zhao, Hui Li, et al.. (2025). Sequential Targeting Chondroitin Sulfate‐Bilirubin Nanomedicine Attenuates Osteoarthritis via Reprogramming Lipid Metabolism in M1 Macrophages. Advanced Science. 12(9). e2411911–e2411911. 11 indexed citations

Cheng, Qingmei, Ke He, Junyu Zhu, et al.. (2024). Memantine attenuates the development of osteoarthritis by blocking NMDA receptor mediated calcium overload and chondrocyte senescence. Journal of Orthopaedic Translation. 48. 204–216. 2 indexed citations

Wang, Yuqing, Qiao Jiang, Huizhong Long, et al.. (2024). Trends and benefits of early hip arthroplasty for femoral neck fracture in China: a national cohort study. International Journal of Surgery. 110(3). 1347–1355. 9 indexed citations

Wei, Jie, Yan Cui, Jialing Wu, et al.. (2023). POS0090 DYSBIOSIS OF GUT MICROBIOME, BILE ACID COMPOSITIONS, AND PREVALENCE OF HYPERURICEMIA: DATA FROM THE XIANGYA HYPERURICEMIA STUDY. Annals of the Rheumatic Diseases. 82. 258–258. 1 indexed citations

Li, Hui, Xiaofeng Jiang, Weiya Zhang, et al.. (2023). Combining single-cell RNA sequencing and population-based studies reveals hand osteoarthritis-associated chondrocyte subpopulations and pathways. Bone Research. 11(1). 58–58. 36 indexed citations

Wang, Yilun, Yuqing Zhang, Nancy E. Lane, et al.. (2022). Population‐based metagenomics analysis reveals altered gut microbiome in sarcopenia: data from the Xiangya Sarcopenia Study. Journal of Cachexia Sarcopenia and Muscle. 13(5). 2340–2351. 62 indexed citations

Deng, Caifeng, Xuan Zhao, Kelong Ai, et al.. (2022). Engineered Platelet Microparticle-Membrane Camouflaged Nanoparticles for Targeting the Golgi Apparatus of Synovial Fibroblasts to Attenuate Rheumatoid Arthritis. ACS Nano. 16(11). 18430–18447. 32 indexed citations

Li, Jiatian, Na Lu, Houchen Lyu, et al.. (2022). Peptic Ulcer Disease and Risk of Hip Fracture: A General Population-based Cohort Study. The Journal of Clinical Endocrinology & Metabolism. 107(9). e3738–e3746. 2 indexed citations

10.

Wang, Yilun, Guanghua Lei, Chao Zeng, et al.. (2020). Comparative Risk‐Benefit Profiles of Individual Devices for Graft Fixation in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Network Meta‐analysis. Arthroscopy The Journal of Arthroscopic and Related Surgery. 36(7). 1953–1972. 10 indexed citations

11.

Xu, Bei, Yilun Wang, Chao Zeng, et al.. (2019). Analgesic efficacy and safety of ketamine after total knee or hip arthroplasty: a meta-analysis of randomised placebo-controlled studies. BMJ Open. 9(9). e028337–e028337. 17 indexed citations

12.

Zeng, Chao, Yusheng Li, Jie Wei, et al.. (2016). Analgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis. Scientific Reports. 6(1). 38024–38024. 14 indexed citations

13.

Zhang, Yi, Tuo Yang, Chao Zeng, et al.. (2016). Is coffee consumption associated with a lower risk of hyperuricaemia or gout? A systematic review and meta-analysis. BMJ Open. 6(7). e009809–e009809. 30 indexed citations

14.

Zhang, Yi, Chao Zeng, Jie Wei, et al.. (2016). Associations of cigarette smoking, betel quid chewing and alcohol consumption with high-sensitivity C-reactive protein in early radiographic knee osteoarthritis: a cross-sectional study. BMJ Open. 6(3). e010763–e010763. 9 indexed citations

15.

Yang, Tuo, Yi Zhang, Jie Wei, et al.. (2016). Relationship between cigarette smoking and hyperuricemia in middle-aged and elderly population: a cross-sectional study. Rheumatology International. 37(1). 131–136. 23 indexed citations

16.

Zhou, Yang, Tubao Yang, Jie Wei, et al.. (2015). Single-dose intra-articular ropivacaine after arthroscopic knee surgery decreases post-operative pain without increasing side effects: a systematic review and meta-analysis. Knee Surgery Sports Traumatology Arthroscopy. 24(5). 1651–1659. 23 indexed citations

17.

Wei, Jie, Guanghua Lei, Shuguang Gao, et al.. (2013). Single-Dose Intra-Articular Bupivacaine Versus Morphine After Arthroscopic Knee Surgery. Clinical Journal of Pain. 30(7). 630–638. 15 indexed citations

18.

Zeng, Chao, Shuguang Gao, Wei Luo, et al.. (2013). Single‐Dose Intra‐Articular Morphine After Arthroscopic Knee Surgery: A Meta‐Analysis of Randomized Placebo‐Controlled Studies. Arthroscopy The Journal of Arthroscopic and Related Surgery. 29(8). 1450–1450. 27 indexed citations

19.

Liu, Hua, Chao Zeng, Shuguang Gao, et al.. (2013). The effect of mud therapy on pain relief in patients with knee osteoarthritis: A meta-analysis of randomized controlled trials. Journal of International Medical Research. 41(5). 1418–1425. 28 indexed citations

20.

Gong, Zhicheng, Guanghua Lei, Lan Fan, et al.. (2011). Serine racemase rs391300 G/A polymorphism influences the therapeutic efficacy of metformin in Chinese patients with diabetes mellitus type 2. Clinical and Experimental Pharmacology and Physiology. 38(12). 824–829. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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