Gert C. Scheper

9.7k citations

80 papers · 3.9k indexed · h-index 37

Impact in

Molecular Biology top 2%
- RNA regulation and disease
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- RNA modifications and cancer
- PI3K/AKT/mTOR signaling in cancer
- Mitochondrial Function and Pathology
Neurology top 2%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in ⓘ

Molecular Biology 68
- RNA regulation and disease 49
- RNA and protein synthesis mechanisms 20
- RNA Research and Splicing 18
- Mitochondrial Function and Pathology 14
- RNA modifications and cancer 9
- PI3K/AKT/mTOR signaling in cancer 8
Cell Biology 14
- Endoplasmic Reticulum Stress and Disease 11

Co-authors: Christopher G. Proud (14 shared papers)Marjo S. van der Knaap (45 shared papers)Harry O. Voorma (10 shared papers)Miranda Kleijn (5 shared papers)Barbara van Kollenburg (7 shared papers)Adri A.M. Thomas (10 shared papers)Jan C. Pronk (7 shared papers)Marianna Bugiani (4 shared papers)
Journals: Journal of Biological Chemistry (6 papers)Journal of Neuropathology & Experimental Neurology (5 papers)Biochemical Journal (5 papers)Journal of Child Neurology (4 papers)European Journal of Biochemistry (3 papers)
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Gert C. Scheper

78 papers receiving 3.8k citations

Peers

Countries citing papers authored by Gert C. Scheper

Since Specialization

Citations

This map shows the geographic impact of Gert C. Scheper's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gert C. Scheper with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gert C. Scheper more than expected).

Fields of papers citing papers by Gert C. Scheper

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gert C. Scheper. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gert C. Scheper. The network helps show where Gert C. Scheper may publish in the future.

Co-authors

The 25 scholars most cited alongside Gert C. Scheper, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gert C. Scheper Line = papers co-authored together Gert C. Scheper links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 80 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation Nature Genetics ·Gert C. Scheper, Thom van der Klok, Rob J. van Andel, Carola G.M. van Berkel, Marie Sissler, Joél Smet, Tatjana I Muravina, S V Serkov, Graziella Uziel, Marianna Bugiani, Raphael Schiffmann, Ingeborg Krägeloh‐Mann, Jan Smeıtınk, Catherine Florentz, Rudy Van Coster, Jan C. Pronk, Marjo S. van der Knaap	2007	329
2	Does phosphorylation of the cap‐binding protein eIF4E play a role in translation initiation? European Journal of Biochemistry ·Gert C. Scheper, Christopher G. Proud	2002	242
3	Phosphorylation of Eukaryotic Initiation Factor 4E Markedly Reduces Its Affinity for Capped mRNA Journal of Biological Chemistry ·Gert C. Scheper, Barbara van Kollenburg, Jianzhong Hu, Yunjing Luo, Dixie J. Goss, Christopher G. Proud	2002	211
4	Translation matters: protein synthesis defects in inherited disease Nature Reviews Genetics ·Gert C. Scheper, Marjo S. van der Knaap, Christopher G. Proud	2007	193
5	The Mitogen-Activated Protein Kinase Signal-Integrating Kinase Mnk2 Is a Eukaryotic Initiation Factor 4E Kinase with High Levels of Basal Activity in Mammalian Cells Molecular and Cellular Biology ·Gert C. Scheper, Nick Morrice, Miranda Kleijn, Christopher G. Proud	2001	175
6	Regulation of translation initiation factors by signal transduction European Journal of Biochemistry ·Miranda Kleijn, Gert C. Scheper, Harry O. Voorma, Adri A. M. Thomas	1998	166
7	Leukoencephalopathy With Vanishing White Matter: A Review Journal of Neuropathology & Experimental Neurology ·Marianna Bugiani, Ilja Boor, James M. Powers, Gert C. Scheper, Marjo S. van der Knaap	2010	127
8	Mutant GlialCAM Causes Megalencephalic Leukoencephalopathy with Subcortical Cysts, Benign Familial Macrocephaly, and Macrocephaly with Retardation and Autism The American Journal of Human Genetics ·Tania López-Hernández, Margreet C. Ridder, Marisol Montolio, Xavier Capdevila‐Nortes, Emiel Polder, Sònia Sirisi, Anna Duarri, Uwe Schulte, Bernd Fakler, Virginia Nunes, Gert C. Scheper, Albert Martı́nez, Raúl Estévez, Marjo S. van der Knaap	2011	124
9	eIF2B-Related Disorders: Antenatal Onset and Involvement of Multiple Organs The American Journal of Human Genetics ·Marjo S. van der Knaap, Carola G.M. van Berkel, Jochen Herms, Rudy Van Coster, Martina Baethmann, Sakkubai Naidu, Eugen Boltshauser, Michèl A.A.P. Willemsen, Barbara Plecko, Georg F. Hoffmann, Christopher G. Proud, Gert C. Scheper, Jan C. Pronk	2003	114
10	Astrocytes are central in the pathomechanisms of vanishing white matter Journal of Clinical Investigation ·Stephanie Dooves, Marianna Bugiani, Nienke L. Postma, Emiel Polder, Niels Land, Stephen T. Horan, Anne‐Lieke F. van Deijk, Aleid van de Kreeke, Gerbren Jacobs, Caroline Vuong, Jan Klooster, Maarten Kamermans, Joke Wortel, Maarten Loos, Lisanne E. Wisse, Gert C. Scheper, Truus E. M. Abbink, Vivi M. Heine, Marjo S. van der Knaap	2016	106
11	Defective Glial Maturation in Vanishing White Matter Disease Journal of Neuropathology & Experimental Neurology ·Marianna Bugiani, Ilja Boor, Barbara van Kollenburg, Nienke L. Postma, Emiel Polder, Carola van Berkel, Ronald E. van Kesteren, Martha S. Windrem, Elly M. Hol, Gert C. Scheper, Steven A. Goldman, Marjo S. van der Knaap	2010	104
12	The N and C Termini of the Splice Variants of the Human Mitogen-Activated Protein Kinase-Interacting Kinase Mnk2 Determine Activity and Localization Molecular and Cellular Biology ·Gert C. Scheper, Josep Lluís Parra, Mary Ann Wilson, Barbara van Kollenburg, Alfred C.O. Vertegaal, Ze‐Guang Han, Christopher G. Proud	2003	92
13	MLC1: A Novel Protein in Distal Astroglial Processes Journal of Neuropathology & Experimental Neurology ·P. K. Ilja Boor, Koen de Groot, Quinten Waisfisz, Wouter Kamphorst, Cees B.M. Oudejans, James M. Powers, Jan C. Pronk, Gert C. Scheper, Marjo S. van der Knaap	2005	81
14	The Unfolded Protein Response in Vanishing White Matter Disease Journal of Neuropathology & Experimental Neurology ·J. Patrick van der Voorn, Barbara van Kollenburg, Gesina A.M. Bertrand, Keith Van Haren, Gert C. Scheper, James M. Powers, Marjo S. van der Knaap	2005	81
15	Glia-Specific Activation of All Pathways of the Unfolded Protein Response in Vanishing White Matter Disease Journal of Neuropathology & Experimental Neurology ·Barbara van Kollenburg, Jantine van Dijk, James Garbern, Adri A.M. Thomas, Gert C. Scheper, James M. Powers, Marjo S. van der Knaap	2006	79
16	Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts Human Molecular Genetics ·Tania López-Hernández, Sònia Sirisi, Xavier Capdevila‐Nortes, Marisol Montolio, Víctor Fernández‐Dueñas, Gert C. Scheper, Marjo S. van der Knaap, Pilar Casquero, Francisco Ciruela, Isidró Ferrer, Virginia Nunes, Raúl Estévez	2011	78
17	A Quantitative Molecular Model for Modulation of Mammalian Translation by the eIF4E-binding Protein 1 Journal of Biological Chemistry ·Muhammad Manjurul Karim, John M.X. Hughes, Jim Warwicker, Gert C. Scheper, Christopher G. Proud, John E.G. McCarthy	2001	68
18	Vanishing white matter disease: A review with focus on its genetics Mental Retardation and Developmental Disabilities Research Reviews ·Jan C. Pronk, Barbara van Kollenburg, Gert C. Scheper, Marjo S. van der Knaap	2006	64
19	Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes Human Mutation ·Rui Liu, Hannemieke D. W. van der Lei, Xuemin Wang, Noel C. Wortham, Hua Tang, Carola G.M. van Berkel, Tsitsi Arikana Mufunde, Weida Huang, Marjo S. van der Knaap, Gert C. Scheper, Christopher G. Proud	2011	59
20	Eukaryotic initiation factors-4E and -4F stimulate 5' cap-dependent as well as internal initiation of protein synthesis. Journal of Biological Chemistry ·Gert C. Scheper, Harry O. Voorma, A.A.M Thomas	1992	59

About Gert C. Scheper

Gert C. Scheper is a scholar working on Molecular Biology, Cell Biology, Otorhinolaryngology, Periodontics and Electrochemistry, having authored 80 papers that have together received 3.9k indexed citations. Recurring topics across this work include RNA regulation and disease (49 papers), RNA and protein synthesis mechanisms (20 papers), RNA Research and Splicing (18 papers), Mitochondrial Function and Pathology (14 papers), Endoplasmic Reticulum Stress and Disease (11 papers), RNA modifications and cancer (9 papers), Viral Infections and Immunology Research (8 papers) and PI3K/AKT/mTOR signaling in cancer (8 papers). The work is most often cited by research in Molecular Biology (3.3k citations), Neurology (366 citations), Cell Biology (481 citations), Clinical Biochemistry (166 citations) and Cellular and Molecular Neuroscience (351 citations). Gert C. Scheper has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Christopher G. Proud, Marjo S. van der Knaap, Harry O. Voorma, Miranda Kleijn, Barbara van Kollenburg, Adri A.M. Thomas, Jan C. Pronk, Marianna Bugiani, James M. Powers and Carola G.M. van Berkel. Their work appears in journals such as Journal of Biological Chemistry, Journal of Neuropathology & Experimental Neurology, Biochemical Journal, Journal of Child Neurology and European Journal of Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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