George M. Spyrou

4.3k total citations · 1 hit paper
165 papers, 3.0k citations indexed

About

George M. Spyrou is a scholar working on Molecular Biology, Radiology, Nuclear Medicine and Imaging and Pulmonary and Respiratory Medicine. According to data from OpenAlex, George M. Spyrou has authored 165 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 80 papers in Molecular Biology, 33 papers in Radiology, Nuclear Medicine and Imaging and 28 papers in Pulmonary and Respiratory Medicine. Recurrent topics in George M. Spyrou's work include Bioinformatics and Genomic Networks (36 papers), Computational Drug Discovery Methods (26 papers) and Digital Radiography and Breast Imaging (20 papers). George M. Spyrou is often cited by papers focused on Bioinformatics and Genomic Networks (36 papers), Computational Drug Discovery Methods (26 papers) and Digital Radiography and Breast Imaging (20 papers). George M. Spyrou collaborates with scholars based in Greece, Cyprus and United Kingdom. George M. Spyrou's co-authors include Zoe Cournia, Demetrios K. Vassilatis, Moshé Yaniv, Marilena M. Bourdakou, Emmanouil Athanasiadis, G. Tzanakos, George Panayiotakis, George Minadakis, Anastasis Oulas and Margarita Zachariou and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

George M. Spyrou

155 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure-Based Virtual Screening for Drug Discovery: Principles, Applications and Recent Advances

2014 676 citations George M. Spyrou, Zoe Cournia et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
George M. Spyrou Greece	24	1.6k	571	331	298	297	165	3.0k
Tim Guilliams United Kingdom	13	2.0k 1.2×	932 1.6×	197 0.6×	168 0.6×	329 1.1×	15	4.0k
Yaning Li China	18	1.4k 0.9×	489 0.9×	273 0.8×	158 0.5×	285 1.0×	56	4.8k
Xiaochen Bo China	31	2.7k 1.6×	567 1.0×	171 0.5×	275 0.9×	196 0.7×	166	4.2k
Qi Liu China	31	2.6k 1.6×	535 0.9×	165 0.5×	171 0.6×	392 1.3×	137	3.6k
Weiwei Xue China	41	3.3k 2.1×	1.0k 1.8×	262 0.8×	186 0.6×	451 1.5×	177	5.7k
Bo Li China	33	2.3k 1.4×	333 0.6×	115 0.3×	210 0.7×	291 1.0×	198	4.3k
Leming Shi China	35	2.0k 1.2×	728 1.3×	127 0.4×	256 0.9×	571 1.9×	97	3.8k
Rengül Çetin-Atalay Türkiye	33	2.0k 1.3×	670 1.2×	98 0.3×	216 0.7×	358 1.2×	140	3.8k
Neema Jamshidi United States	32	2.8k 1.8×	215 0.4×	410 1.2×	238 0.8×	273 0.9×	71	4.0k
Yanqiong Zhang China	39	2.5k 1.6×	353 0.6×	153 0.5×	272 0.9×	507 1.7×	191	5.0k

Countries citing papers authored by George M. Spyrou

Since Specialization

Citations

This map shows the geographic impact of George M. Spyrou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George M. Spyrou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George M. Spyrou more than expected).

Fields of papers citing papers by George M. Spyrou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George M. Spyrou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George M. Spyrou. The network helps show where George M. Spyrou may publish in the future.

Co-authorship network of co-authors of George M. Spyrou

This figure shows the co-authorship network connecting the top 25 collaborators of George M. Spyrou. A scholar is included among the top collaborators of George M. Spyrou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with George M. Spyrou. George M. Spyrou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bourdakou, Marilena M., et al.. (2025). Exploring the Impact of Microgravity on Gene Expression: Dysregulated Pathways and Candidate Repurposed Drugs. International Journal of Molecular Sciences. 26(3). 1287–1287. 3 indexed citations

Fanis, Pavlos, et al.. (2025). Identification of puberty related miRNAs in the hypothalamus of female mice. Molecular and Cellular Endocrinology. 598. 112468–112468. 1 indexed citations

Bourdakou, Marilena M., et al.. (2025). Integrative analysis of proteomic and MRI data reveals protein associations with brain imaging features in Alzheimer’s disease. Expert Review of Proteomics. 22(11-12). 551–567.

Karathanasis, Nestoras & George M. Spyrou. (2025). Predicting the Progression from Asymptomatic to Symptomatic Multiple Myeloma and Stage Classification Using Gene Expression Data. Cancers. 17(2). 332–332. 1 indexed citations

Zachariou, Margarita, et al.. (2025). Integrating imaging and omics for enhanced subtyping of mild cognitive impairment associated with Alzheimer’s disease. Journal of Translational Medicine. 23(1). 1240–1240.

Lygirou, Vasiliki, Manousos Makridakis, George M. Spyrou, et al.. (2025). Proteomic Analysis of Bone Marrow CD138+ Cells to Identify Proteins Associated With the Response of Multiple Myeloma Patients to Commonly Used Therapeutic Regimens. PROTEOMICS. 25(16). 48–60. 1 indexed citations

Tomazou, Marios, Chrysovalantis Voutouri, Christina Michael, et al.. (2024). Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes. Cell Reports. 43(3). 113859–113859. 1 indexed citations

Bourdakou, Marilena M., Eleni Melliou, Prokopios Magiatis, & George M. Spyrou. (2024). Computational investigation of the functional landscape of the protective role that extra virgin olive oil consumption may have on chronic lymphocytic leukemia. Journal of Translational Medicine. 22(1). 869–869. 1 indexed citations

Zachariou, Margarita, et al.. (2023). Preliminary In Vitro and In Vivo Insights of In Silico Candidate Repurposed Drugs for Alzheimer’s Disease. Life. 13(5). 1095–1095. 3 indexed citations

10.

Koutsoulidou, Andrie, Anastasis Oulas, Marios Tomazou, et al.. (2022). Serum miRNAs as biomarkers for the rare types of muscular dystrophy. Neuromuscular Disorders. 32(4). 332–346. 7 indexed citations

11.

Spyrou, George M., et al.. (2021). Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. Briefings in Bioinformatics. 22(6). 12 indexed citations

12.

Tomazou, Marios, Marilena M. Bourdakou, George Minadakis, et al.. (2021). Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19. Briefings in Bioinformatics. 22(6). 22 indexed citations

13.

Karatzas, Evangelos, et al.. (2021). Fibrotic expression profile analysis reveals repurposed drugs with potential anti-fibrotic mode of action. PLoS ONE. 16(4). e0249687–e0249687. 10 indexed citations

14.

Karatzas, Evangelos, et al.. (2020). ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing. Bioinformatics. 36(8). 2602–2604. 24 indexed citations

15.

Karatzas, Evangelos, Margarita Zachariou, Marilena M. Bourdakou, et al.. (2020). PathWalks: identifying pathway communities using a disease-related map of integrated information. Bioinformatics. 36(13). 4070–4079. 6 indexed citations

16.

Tomazou, Marios, et al.. (2020). Analyzing Gene Expression Profiles from Ataxia and Spasticity Phenotypes to Reveal Spastic Ataxia Related Pathways. International Journal of Molecular Sciences. 21(18). 6722–6722. 5 indexed citations

17.

Dovrolis, Nikolas, George Kolios, George M. Spyrou, & Ιωάννα Μαρουλάκου. (2017). Laying in silico pipelines for drug repositioning: a paradigm in ensemble analysis for neurodegenerative diseases. Drug Discovery Today. 22(5). 805–813. 18 indexed citations

18.

Stefanaki, Irene, Christina M. Lill, Katerina Kypreou, et al.. (2014). Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene Database. Journal of Investigative Dermatology. 135(4). 1074–1079. 25 indexed citations

19.

Valavanis, Ioannis, George M. Spyrou, & Konstantina S. Nikita. (2010). A similarity network approach for the analysis and comparison of protein sequence/structure sets. Journal of Biomedical Informatics. 43(2). 257–267. 14 indexed citations

20.

Hirai, S, Masaki Izawa, Shin‐Ichi Osada, George M. Spyrou, & Shigeo Ohno. (1996). Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK.. PubMed. 12(3). 641–50. 116 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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