Frank Jacobs

3.4k total citations · 1 hit paper
62 papers, 2.2k citations indexed

About

Frank Jacobs is a scholar working on Molecular Biology, Surgery and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Frank Jacobs has authored 62 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 18 papers in Surgery and 16 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Frank Jacobs's work include Virus-based gene therapy research (11 papers), CRISPR and Genetic Engineering (9 papers) and Pharmacogenetics and Drug Metabolism (7 papers). Frank Jacobs is often cited by papers focused on Virus-based gene therapy research (11 papers), CRISPR and Genetic Engineering (9 papers) and Pharmacogenetics and Drug Metabolism (7 papers). Frank Jacobs collaborates with scholars based in Belgium, United States and Germany. Frank Jacobs's co-authors include Bart De Geest, Eline Van Craeyveld, Jan Snoeys, Stephanie Gordts, P.M. Frederik, Ilayaraja Muthuramu, Baki Topal, E. Wisse, Eddie Wisse and Yingmei Feng and has published in prestigious journals such as Blood, Journal of the American College of Cardiology and PLoS ONE.

In The Last Decade

Frank Jacobs

58 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

2016 517 citations Frank Jacobs, Jan Snoeys et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Frank Jacobs Belgium	27	875	594	395	366	349	62	2.2k
Yingchao Wang China	32	2.3k 2.6×	487 0.8×	204 0.5×	135 0.4×	160 0.5×	148	3.7k
Tadayoshi Okumura Japan	25	686 0.8×	356 0.6×	83 0.2×	297 0.8×	99 0.3×	76	2.0k
Bruno Baudin France	24	647 0.7×	225 0.4×	408 1.0×	98 0.3×	129 0.4×	80	1.9k
Maria Franzini Italy	26	726 0.8×	340 0.6×	494 1.3×	208 0.6×	93 0.3×	92	2.2k
Satoshi Kobayashi Japan	30	1.0k 1.2×	768 1.3×	81 0.2×	414 1.1×	240 0.7×	213	3.3k
Kazuhiro Katayama Japan	30	1.3k 1.5×	500 0.8×	347 0.9×	459 1.3×	87 0.2×	136	3.3k
Lionel Hebbard Australia	32	1.2k 1.4×	200 0.3×	128 0.3×	326 0.9×	111 0.3×	51	2.7k
Bart De Geest Belgium	35	1.3k 1.5×	871 1.5×	788 2.0×	86 0.2×	105 0.3×	98	3.0k
Yasuji Seyama Japan	28	642 0.7×	1.1k 1.9×	126 0.3×	466 1.3×	47 0.1×	115	2.6k
Junli Guo China	32	1.2k 1.4×	333 0.6×	194 0.5×	314 0.9×	55 0.2×	96	2.4k

Countries citing papers authored by Frank Jacobs

Since Specialization

Citations

This map shows the geographic impact of Frank Jacobs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Jacobs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Jacobs more than expected).

Fields of papers citing papers by Frank Jacobs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Jacobs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Jacobs. The network helps show where Frank Jacobs may publish in the future.

Co-authorship network of co-authors of Frank Jacobs

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Jacobs. A scholar is included among the top collaborators of Frank Jacobs based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Jacobs. Frank Jacobs is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Vries, Ronald P. de, Frank Jacobs, Geert Mannens, et al.. (2019). Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes. Drug Metabolism and Disposition. 47(5). 453–464. 29 indexed citations

Jacobs, Frank, Jan Snoeys, Jos Van Houdt, et al.. (2017). In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs. Pharmaceutical Research. 34(4). 750–764. 11 indexed citations

Muthuramu, Ilayaraja, et al.. (2015). Selective homocysteine-lowering gene transfer attenuates pressure overload-induced cardiomyopathy via reduced oxidative stress. Journal of Molecular Medicine. 93(6). 609–618. 35 indexed citations

Muthuramu, Ilayaraja, Marleen Lox, Frank Jacobs, & Bart De Geest. (2014). Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure. Journal of Visualized Experiments. 41 indexed citations

Jacobs, Frank, Leanne de Koning, Linh‐Chi Bui, et al.. (2013). Hepatocyte-specific Dyrk1a gene transfer rescues plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic mice. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832(6). 718–728. 13 indexed citations

Gordts, Stephanie, Ilayaraja Muthuramu, Elena Nefyodova, et al.. (2013). Beneficial effects of selective HDL-raising gene transfer on survival, cardiac remodelling and cardiac function after myocardial infarction in mice. Gene Therapy. 20(11). 1053–1061. 34 indexed citations

Muthuramu, Ilayaraja, Frank Jacobs, Neha Singh, Stephanie Gordts, & Bart De Geest. (2013). Selective Homocysteine Lowering Gene Transfer Improves Infarct Healing, Attenuates Remodelling, and Enhances Diastolic Function after Myocardial Infarction in Mice. PLoS ONE. 8(5). e63710–e63710. 8 indexed citations

Singh, Neha, Eline Van Craeyveld, Marc Tjwa, et al.. (2012). Circulating Apoptotic Endothelial Cells and Apoptotic Endothelial Microparticles Independently Predict the Presence of Cardiac Allograft Vasculopathy. Journal of the American College of Cardiology. 60(4). 324–331. 39 indexed citations

Gordts, Stephanie, Eline Van Craeyveld, Ilayaraja Muthuramu, et al.. (2012). Lipid Lowering and HDL Raising Gene Transfer Increase Endothelial Progenitor Cells, Enhance Myocardial Vascularity, and Improve Diastolic Function. PLoS ONE. 7(10). e46849–e46849. 24 indexed citations

10.

Jacobs, Frank, Eline Van Craeyveld, Ilayaraja Muthuramu, et al.. (2011). Correction of endothelial dysfunction after selective homocysteine lowering gene therapy reduces arterial thrombogenicity but has no effect on atherogenesis. Journal of Molecular Medicine. 89(10). 1051–1058. 8 indexed citations

11.

Wellhöner, Peter, et al.. (2011). Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4–10) in humans causes lipolysis in white adipose tissue. International Journal of Obesity. 36(5). 703–708. 17 indexed citations

12.

Craeyveld, Eline Van, Stephanie Gordts, Frank Jacobs, & Bart De Geest. (2011). Correlation of atherosclerosis between different topographic sites is highly dependent on the type of hyperlipidemia. Heart and Vessels. 27(2). 231–234. 6 indexed citations

13.

Jacobs, Frank, Eline Van Craeyveld, Yingmei Feng, & Bart De Geest. (2009). The diameter of liver sinusoidal fenestrae is not a major determinant of lipoprotein levels and atherosclerosis in cholesterol-fed rabbits. Cardiovascular Pathology. 20(1). 44–50. 3 indexed citations

14.

Craeyveld, Eline Van, Joke Lievens, Frank Jacobs, et al.. (2009). Apolipoprotein A-I and lecithin:cholesterol acyltransferase transfer induce cholesterol unloading in complex atherosclerotic lesions. Gene Therapy. 16(6). 757–765. 20 indexed citations

15.

Jacobs, Frank, Eddie Wisse, & Bart De Geest. (2009). Early effect of a single intravenous injection of ethanol on hepatic sinusoidal endothelial fenestrae in rabbits. PubMed. 8(1). 4–4. 1 indexed citations

16.

Jacobs, Frank, Yingmei Feng, Eline Van Craeyveld, et al.. (2009). Species Differences in Hepatocyte-Directed Gene Transfer: Implications for Clinical Translation. Current Gene Therapy. 9(2). 83–90. 6 indexed citations

17.

Feng, Yingmei, Frank Jacobs, Eline Van Craeyveld, et al.. (2009). The impact of antigen expression in antigen-presenting cells on humoral immune responses against the transgene product. Gene Therapy. 17(2). 288–293. 7 indexed citations

18.

Wisse, E., Frank Jacobs, Baki Topal, P.M. Frederik, & Bart De Geest. (2008). The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer. Gene Therapy. 15(17). 1193–1199. 235 indexed citations

19.

Jacobs, Frank, Jan Snoeys, Yingmei Feng, et al.. (2008). Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer. Gene Therapy. 15(8). 594–603. 51 indexed citations

20.

Ibrahim, Sherif, Frank Jacobs, David R. Holt, et al.. (1996). Immunohistochemical manifestations of unilateral kidney ischemia. Clinical Transplantation. 10(6pt2). 646–652. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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