Eric C. Lai

32.2k total citations · 11 hit papers
198 papers, 21.3k citations indexed

About

Eric C. Lai is a scholar working on Molecular Biology, Cancer Research and Plant Science. According to data from OpenAlex, Eric C. Lai has authored 198 papers receiving a total of 21.3k indexed citations (citations by other indexed papers that have themselves been cited), including 172 papers in Molecular Biology, 87 papers in Cancer Research and 40 papers in Plant Science. Recurrent topics in Eric C. Lai's work include MicroRNA in disease regulation (82 papers), RNA Research and Splicing (74 papers) and RNA modifications and cancer (42 papers). Eric C. Lai is often cited by papers focused on MicroRNA in disease regulation (82 papers), RNA Research and Splicing (74 papers) and RNA modifications and cancer (42 papers). Eric C. Lai collaborates with scholars based in United States, Japan and United Kingdom. Eric C. Lai's co-authors include Katsutomo Okamura, Jakub Orzechowski Westholm, Gerald M. Rubin, Alex S. Flynt, Jr-Shiuan Yang, David M. Tyler, Hong Duan, Joshua W. Hagen, James W. Posakony and Pavel Tomančák and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Eric C. Lai

197 papers receiving 21.0k citations

Hit Papers

Micro RNAs are complementary to 3′ UTR sequence motifs th... 2002 2026 2010 2018 2002 2004 2014 2007 2008 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation
    2002 1.2k citations Eric C. Lai profile →
  2. Notch signaling: control of cell communication and cell fate
    2004 825 citations Eric C. Lai Development profile →
  3. Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation
    2014 774 citations Jakub Orzechowski Westholm, S Celniker et al. profile →
  4. The Mirtron Pathway Generates microRNA-Class Regulatory RNAs in Drosophila
    2007 754 citations Katsutomo Okamura, Joshua W. Hagen et al. profile →
  5. Biological principles of microRNA-mediated regulation: shared themes amid diversity
    2008 649 citations Alex S. Flynt, Eric C. Lai profile →
  6. Unlocking the secrets of the genome
    2009 609 citations S Celniker, Laura A. L. Dillon et al. profile →
  7. Mammalian Mirtron Genes
    2007 585 citations Eric C. Lai et al. profile →
  8. Computational identification of DrosophilamicroRNA genes
    2003 582 citations Eric C. Lai, Gerald M. Rubin et al. profile →
  9. miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
    2011 542 citations Peter Smibert, Eric C. Lai et al. Proceedings of the National Academy of Sciences profile →
  10. microRNAs in action: biogenesis, function and regulation
    2023 443 citations Seungjae Lee, Eric C. Lai et al. profile →
  11. Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs
    2010 375 citations Qingfa Wu, Yingjun Luo et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Eric C. Lai United States 71 17.2k 10.0k 3.4k 1.6k 1.5k 198 21.3k
Richard W. Carthew United States 52 13.1k 0.8× 4.8k 0.5× 2.5k 0.7× 1.8k 1.2× 1.7k 1.1× 105 17.0k
Scott M. Hammond United States 50 24.3k 1.4× 15.0k 1.5× 2.7k 0.8× 1.9k 1.2× 1.8k 1.2× 72 28.8k
Alexander Stark Austria 61 17.4k 1.0× 6.1k 0.6× 4.8k 1.4× 2.1k 1.4× 1.1k 0.7× 122 20.4k
Piero Carninci Japan 73 17.1k 1.0× 4.6k 0.5× 5.5k 1.6× 2.4k 1.5× 1.9k 1.2× 307 22.8k
Christopher B. Burge United States 66 33.4k 1.9× 16.7k 1.7× 3.4k 1.0× 2.4k 1.5× 2.1k 1.4× 119 39.7k
Phillip D. Zamore United States 86 32.6k 1.9× 12.7k 1.3× 9.6k 2.8× 3.1k 2.0× 2.1k 1.4× 165 38.1k
Michael T. McManus United States 67 15.4k 0.9× 8.2k 0.8× 1.7k 0.5× 2.1k 1.4× 2.0k 1.3× 202 20.9k
Sam Griffiths‐Jones United Kingdom 39 23.2k 1.3× 16.9k 1.7× 5.3k 1.6× 1.8k 1.2× 1.7k 1.1× 78 30.4k
Witold Filipowicz Switzerland 69 23.8k 1.4× 14.4k 1.4× 3.2k 0.9× 1.3k 0.8× 1.9k 1.2× 162 28.9k

Countries citing papers authored by Eric C. Lai

Since Specialization
Citations

This map shows the geographic impact of Eric C. Lai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric C. Lai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric C. Lai more than expected).

Fields of papers citing papers by Eric C. Lai

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric C. Lai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric C. Lai. The network helps show where Eric C. Lai may publish in the future.

Co-authorship network of co-authors of Eric C. Lai

This figure shows the co-authorship network connecting the top 25 collaborators of Eric C. Lai. A scholar is included among the top collaborators of Eric C. Lai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric C. Lai. Eric C. Lai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kim, Bernard, et al.. (2025). Double trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years. Nature Communications. 16(1). 516–516. 2 indexed citations
2.
Vattathil, Selina, Ekaterina S. Gerasimov, Adriana Lori, et al.. (2024). Mapping the microRNA landscape in the older adult brain and its genetic contribution to neuropsychiatric conditions. Nature Aging. 5(2). 306–319. 3 indexed citations
3.
Lai, Eric C., et al.. (2023). A tailed mirtron promotes longevity in Drosophila. Nucleic Acids Research. 52(3). 1080–1089. 2 indexed citations
4.
Lai, Eric C. & Aaron A. Vogan. (2023). Proliferation and dissemination of killer meiotic drive loci. Current Opinion in Genetics & Development. 82. 102100–102100. 7 indexed citations
5.
Samani, Adrienne, Michael A. Lopez, Michael J. Conklin, et al.. (2022). miR-486 is essential for muscle function and suppresses a dystrophic transcriptome. Life Science Alliance. 5(9). e202101215–e202101215. 17 indexed citations
6.
Lee, Seungjae, Yen‐Chung Chen, Austin E. Gillen, et al.. (2022). Diverse cell-specific patterns of alternative polyadenylation in Drosophila. Nature Communications. 13(1). 5372–5372. 13 indexed citations
7.
Lee, Seungjae, Wei Lü, Raeann Goering, et al.. (2021). ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. PLoS Genetics. 17(4). e1009439–e1009439. 34 indexed citations
8.
Fulga, Tudor A., Elizabeth M. McNeill, Richard Binari, et al.. (2015). A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs. Nature Communications. 6(1). 7279–7279. 58 indexed citations
9.
Mohammed, Jaaved, Adam Siepel, & Eric C. Lai. (2014). Diverse modes of evolutionary emergence and flux of conserved microRNA clusters. RNA. 20(12). 1850–1863. 35 indexed citations
10.
Smibert, Peter, Jr-Shiuan Yang, Ghows Azzam, Jilong Liu, & Eric C. Lai. (2013). Homeostatic control of Argonaute stability by microRNA availability. Nature Structural & Molecular Biology. 20(7). 789–795. 115 indexed citations
11.
Aoki, Tsutomu, Daniel Wolle, Ella Preger‐Ben Noon, et al.. (2013). Bi-functional cross-linking reagents efficiently capture protein-DNA complexes in Drosophila embryos. Fly. 8(1). 43–51. 12 indexed citations
12.
Sun, Kailiang, Jakub Orzechowski Westholm, Kazuya Tsurudome, et al.. (2012). Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants. PLoS Genetics. 8(2). e1002515–e1002515. 48 indexed citations
13.
Dai, Qi, Peter Smibert, & Eric C. Lai. (2012). Exploiting Drosophila Genetics to Understand MicroRNA Function and Regulation. Current topics in developmental biology. 99. 201–235. 17 indexed citations
14.
Wu, Qingfa, Yingjun Luo, Rui Lu, et al.. (2010). Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs. Proceedings of the National Academy of Sciences. 107(4). 1606–1611. 375 indexed citations breakdown →
15.
Yang, Jr-Shiuan, Thomas Maurin, Nicolas Robine, et al.. (2010). Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proceedings of the National Academy of Sciences. 107(34). 15163–15168. 368 indexed citations
16.
Celniker, S, Laura A. L. Dillon, Mark Gerstein, et al.. (2009). Unlocking the Secrets of the Genome. Carolina Digital Repository (University of North Carolina at Chapel Hill). 1 indexed citations
17.
Okamura, Katsutomo, Wei‐Jen Chung, & Eric C. Lai. (2008). The long and short of inverted repeat genes in animals: MicroRNAs, mirtrons and hairpin RNAs. Cell Cycle. 7(18). 2840–2845. 57 indexed citations
18.
Silver, Serena J., Joshua W. Hagen, Katsutomo Okamura, Norbert Perrimon, & Eric C. Lai. (2007). Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proceedings of the National Academy of Sciences. 104(46). 18151–18156. 80 indexed citations
19.
Lai, Eric C., et al.. (2005). Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. Genes & Development. 19(9). 1067–1080. 246 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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