Eileen K. Jaffe

3.7k total citations
84 papers, 2.9k citations indexed

About

Eileen K. Jaffe is a scholar working on Molecular Biology, Rheumatology and Materials Chemistry. According to data from OpenAlex, Eileen K. Jaffe has authored 84 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 79 papers in Molecular Biology, 39 papers in Rheumatology and 19 papers in Materials Chemistry. Recurrent topics in Eileen K. Jaffe's work include Porphyrin Metabolism and Disorders (55 papers), Biochemical and Molecular Research (44 papers) and Folate and B Vitamins Research (39 papers). Eileen K. Jaffe is often cited by papers focused on Porphyrin Metabolism and Disorders (55 papers), Biochemical and Molecular Research (44 papers) and Folate and B Vitamins Research (39 papers). Eileen K. Jaffe collaborates with scholars based in United States, Switzerland and New Zealand. Eileen K. Jaffe's co-authors include Mélanie Cohn, Mildred Cohn, Linda Stith, Sarah H. Lawrence, Trevor Selwood, George D. Markham, Jukka Kervinen, Roland L. Dunbrack, Jacob Martins and Lei Tang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Eileen K. Jaffe

83 papers receiving 2.7k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Eileen K. Jaffe United States 32 2.2k 619 562 240 219 84 2.9k
A. Ian Scott United States 39 3.2k 1.4× 869 1.4× 727 1.3× 331 1.4× 104 0.5× 237 4.7k
Neal J. Stolowich United States 29 1.6k 0.8× 516 0.8× 267 0.5× 101 0.4× 55 0.3× 74 2.2k
Richard B. Honzatko United States 36 3.3k 1.5× 207 0.3× 1.3k 2.4× 240 1.0× 307 1.4× 109 4.7k
Paul M. Horowitz United States 28 1.5k 0.7× 157 0.3× 531 0.9× 118 0.5× 55 0.3× 114 2.3k
G. Jogl United States 28 1.6k 0.7× 192 0.3× 343 0.6× 115 0.5× 57 0.3× 55 2.2k
Roberts A. Smith United States 31 1.7k 0.8× 246 0.4× 201 0.4× 231 1.0× 71 0.3× 90 2.9k
Frank J. Ruzicka United States 27 1.7k 0.8× 113 0.2× 389 0.7× 154 0.6× 134 0.6× 48 2.7k
Finian J. Leeper United Kingdom 36 2.5k 1.1× 369 0.6× 497 0.9× 91 0.4× 93 0.4× 179 4.7k
Stephen A. Kuby United States 32 2.7k 1.2× 116 0.2× 589 1.0× 303 1.3× 115 0.5× 62 3.8k
B.T. Eger Canada 21 1.6k 0.7× 261 0.4× 123 0.2× 129 0.5× 110 0.5× 23 2.6k

Countries citing papers authored by Eileen K. Jaffe

Since Specialization
Citations

This map shows the geographic impact of Eileen K. Jaffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eileen K. Jaffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eileen K. Jaffe more than expected).

Fields of papers citing papers by Eileen K. Jaffe

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eileen K. Jaffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eileen K. Jaffe. The network helps show where Eileen K. Jaffe may publish in the future.

Co-authorship network of co-authors of Eileen K. Jaffe

This figure shows the co-authorship network connecting the top 25 collaborators of Eileen K. Jaffe. A scholar is included among the top collaborators of Eileen K. Jaffe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eileen K. Jaffe. Eileen K. Jaffe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Merkel, George, et al.. (2020). Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase. Biochimie. 183. 63–77. 3 indexed citations
2.
Gupta, Kushol, et al.. (2019). Biophysical characterization of full-length human phenylalanine hydroxylase provides a deeper understanding of its quaternary structure equilibrium. Journal of Biological Chemistry. 294(26). 10131–10145. 17 indexed citations
3.
Jaffe, Eileen K.. (2019). Porphobilinogen synthase: An equilibrium of different assemblies in human health. Progress in molecular biology and translational science. 169. 85–104. 11 indexed citations
4.
Jaffe, Eileen K.. (2017). New protein structures provide an updated understanding of phenylketonuria. Molecular Genetics and Metabolism. 121(4). 289–296. 21 indexed citations
5.
Lawrence, Sarah, Trevor Selwood, & Eileen K. Jaffe. (2013). Environmental Contaminants Perturb Fragile Protein Assemblies and Inhibit Normal Protein Function. Current Chemical Biology. 7(2). 196–206. 7 indexed citations
6.
Jaffe, Eileen K.. (2013). Impact of Quaternary Structure Dynamics on Allosteric Drug Discovery. Current Topics in Medicinal Chemistry. 13(1). 55–63. 13 indexed citations
7.
Selwood, Trevor & Eileen K. Jaffe. (2011). Dynamic dissociating homo-oligomers and the control of protein function. Archives of Biochemistry and Biophysics. 519(2). 131–143. 86 indexed citations
8.
Stith, Linda, et al.. (2010). Docking to Large Allosteric Binding Sites on Protein Surfaces. Advances in experimental medicine and biology. 680. 481–488. 11 indexed citations
9.
Lawrence, Sarah H., et al.. (2008). Shape Shifting Leads to Small-Molecule Allosteric Drug Discovery. Chemistry & Biology. 15(6). 586–596. 55 indexed citations
10.
Tang, Lei, Sabine Breinig, Linda Stith, et al.. (2005). Single Amino Acid Mutations Alter the Distribution of Human Porphobilinogen Synthase Quaternary Structure Isoforms (Morpheeins). Journal of Biological Chemistry. 281(10). 6682–6690. 28 indexed citations
11.
Jaffe, Eileen K.. (2005). Morpheeins – a new structural paradigm for allosteric regulation. Trends in Biochemical Sciences. 30(9). 490–497. 118 indexed citations
12.
Kundrat, Lenka, Jacob Martins, Linda Stith, Roland L. Dunbrack, & Eileen K. Jaffe. (2003). A Structural Basis for Half-of-the-sites Metal Binding Revealed in Drosophila melanogaster Porphobilinogen Synthase. Journal of Biological Chemistry. 278(33). 31325–31330. 15 indexed citations
13.
Jaffe, Eileen K.. (2003). An Unusual Phylogenetic Variation in the Metal Ion Binding Sites of Porphobilinogen Synthase. Chemistry & Biology. 10(1). 25–34. 59 indexed citations
14.
Jaffe, Eileen K., et al.. (1995). The Phylogenetically Conserved Histidines of Escherichia coli Porphobilinogen Synthase Are Not Required for Catalysis. Journal of Biological Chemistry. 270(41). 24054–24059. 10 indexed citations
15.
16.
Markham, George D., et al.. (1993). Spatial proximity and sequence localization of the reactive sulfhydryls of porphobilinogen synthase. Protein Science. 2(1). 71–79. 20 indexed citations
17.
Jaffe, Eileen K., et al.. (1992). 5-Chlorolevulinate modification of porphobilinogen synthase identifies a potential role for the catalytic zinc. Biochemistry. 31(7). 2113–2123. 41 indexed citations
18.
Jaffe, Eileen K. & George D. Markham. (1988). Carbon-13 NMR studies of methylene and methine carbons of substrate bound to a 280,000-dalton protein, porphobilinogen synthase. Biochemistry. 27(12). 4475–4481. 24 indexed citations
19.
Jaffe, Eileen K. & George D. Markham. (1987). Carbon-13 NMR studies of porphobilinogen synthase: observation of intermediates bound to a 280,000-dalton protein. Biochemistry. 26(14). 4258–4264. 26 indexed citations
20.
Jaffe, Eileen K., et al.. (1986). Dissection of the early steps in the porphobilinogen synthase catalyzed reaction. Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States). 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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