Edward D. Karoly

7.4k total citations · 2 hit papers
55 papers, 4.8k citations indexed

About

Edward D. Karoly is a scholar working on Molecular Biology, Cancer Research and Health, Toxicology and Mutagenesis. According to data from OpenAlex, Edward D. Karoly has authored 55 papers receiving a total of 4.8k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 17 papers in Cancer Research and 11 papers in Health, Toxicology and Mutagenesis. Recurrent topics in Edward D. Karoly's work include Metabolomics and Mass Spectrometry Studies (20 papers), Cancer, Hypoxia, and Metabolism (12 papers) and Air Quality and Health Impacts (8 papers). Edward D. Karoly is often cited by papers focused on Metabolomics and Mass Spectrometry Studies (20 papers), Cancer, Hypoxia, and Metabolism (12 papers) and Air Quality and Health Impacts (8 papers). Edward D. Karoly collaborates with scholars based in United States, United Kingdom and Germany. Edward D. Karoly's co-authors include Robert P. Mohney, Lauren N. Bell, Kankana Bardhan, Bianling Liu, Nikolaos Patsoukis, Lequn Li, Pankaj Seth, Vassiliki A. Boussiotis, Pranam Chatterjee and Gordon J. Freeman and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

Edward D. Karoly

55 papers receiving 4.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

2015 908 citations Edward D. Karoly et al. Nature Communications profile →
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

2013 718 citations Edward D. Karoly, Robert P. Mohney et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Edward D. Karoly United States	32	2.1k	1.3k	1.2k	942	623	55	4.8k
Lei Wang China	42	3.3k 1.6×	833 0.7×	1.1k 0.9×	658 0.7×	614 1.0×	310	6.5k
Lee M. Graves United States	52	5.3k 2.5×	734 0.6×	926 0.8×	1.2k 1.3×	734 1.2×	173	8.0k
Shuhei Tomita Japan	36	1.7k 0.8×	499 0.4×	956 0.8×	737 0.8×	633 1.0×	132	4.4k
Jan Korbecki Poland	25	1.2k 0.6×	1.0k 0.8×	514 0.4×	790 0.8×	278 0.4×	57	3.5k
David H. Sherr United States	48	3.7k 1.8×	3.4k 2.7×	1.9k 1.6×	1.5k 1.5×	604 1.0×	142	9.0k
Ying Xin China	37	2.9k 1.4×	552 0.4×	700 0.6×	707 0.8×	562 0.9×	235	5.7k
Ines Barone Italy	43	1.8k 0.9×	305 0.2×	1.0k 0.9×	1.1k 1.2×	419 0.7×	115	4.1k
Arthur C.K. Chung Hong Kong	39	3.4k 1.7×	454 0.4×	1.5k 1.3×	263 0.3×	274 0.4×	58	6.2k
Corinne Dupuy France	41	1.9k 0.9×	1.3k 1.0×	357 0.3×	436 0.5×	1.2k 1.9×	89	4.9k
Zhiheng He China	35	1.7k 0.8×	558 0.4×	388 0.3×	552 0.6×	777 1.2×	99	4.8k

Countries citing papers authored by Edward D. Karoly

Since Specialization

Citations

This map shows the geographic impact of Edward D. Karoly's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward D. Karoly with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward D. Karoly more than expected).

Fields of papers citing papers by Edward D. Karoly

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward D. Karoly. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward D. Karoly. The network helps show where Edward D. Karoly may publish in the future.

Co-authorship network of co-authors of Edward D. Karoly

This figure shows the co-authorship network connecting the top 25 collaborators of Edward D. Karoly. A scholar is included among the top collaborators of Edward D. Karoly based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward D. Karoly. Edward D. Karoly is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Li, Veronica L., Shuke Xiao, Pascal Schlosser, et al.. (2024). SLC17A1/3 transporters mediate renal excretion of Lac-Phe in mice and humans. Nature Communications. 15(1). 6895–6895. 5 indexed citations

Kotsis, Fruzsina, Ulla T. Schultheiß, Matthias Wuttke, et al.. (2021). Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study. Journal of the American Society of Nephrology. 32(9). 2315–2329. 8 indexed citations

Jamshidi, Neema, Xiuling Xu, Katharina von Löhneysen, et al.. (2020). Metabolome Changes during In Vivo Red Cell Aging Reveal Disruption of Key Metabolic Pathways. iScience. 23(10). 101630–101630. 13 indexed citations

Capel, Frédéric, Vanina Bongard, Corinne Malpuech‐Brugère, et al.. (2019). Metabolomics reveals plausible interactive effects between dairy product consumption and metabolic syndrome in humans. Clinical Nutrition. 39(5). 1497–1509. 15 indexed citations

Waitkus, Matthew S., Christopher J. Pirozzi, Casey J. Moure, et al.. (2017). Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities. Cancer Research. 78(1). 36–50. 33 indexed citations

Oginuma, Masayuki, Philippe Moncuquet, Fengzhu Xiong, et al.. (2017). A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos. Developmental Cell. 40(4). 342–353.e10. 139 indexed citations

Montrose, David C., Xi Kathy Zhou, Rhonda K. Yantiss, et al.. (2016). Celecoxib Alters the Intestinal Microbiota and Metabolome in Association with Reducing Polyp Burden. Cancer Prevention Research. 9(9). 721–731. 35 indexed citations

Miller, Desinia B., Andrew J. Ghio, Edward D. Karoly, et al.. (2016). Ozone Exposure Increases Circulating Stress Hormones and Lipid Metabolites in Humans. American Journal of Respiratory and Critical Care Medicine. 193(12). 1382–1391. 170 indexed citations

James, Emma L., et al.. (2016). Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism. Scientific Reports. 6(1). 38489–38489. 30 indexed citations

10.

Halama, Anna, Bella S. Guerrouahen, Jennifer Pasquier, et al.. (2015). Metabolic signatures differentiate ovarian from colon cancer cell lines. Journal of Translational Medicine. 13(1). 223–223. 30 indexed citations

11.

Kühn, Joachim, Ryan D. Michalek, Edward D. Karoly, et al.. (2014). Large-Scaled Metabolic Profiling of Human Dermal Fibroblasts Derived from Pseudoxanthoma Elasticum Patients and Healthy Controls. PLoS ONE. 9(9). e108336–e108336. 22 indexed citations

12.

Chaudhri, Virendra K., Raffaella Sordella, Edward D. Karoly, et al.. (2013). Metabolic Alterations in Lung Cancer–Associated Fibroblasts Correlated with Increased Glycolytic Metabolism of the Tumor. Molecular Cancer Research. 11(6). 579–592. 77 indexed citations

13.

Dulin, Jennifer N., Edward D. Karoly, Ying Wang, Henry W. Strobel, & Raymond J. Grill. (2013). Licofelone Modulates Neuroinflammation and Attenuates Mechanical Hypersensitivity in the Chronic Phase of Spinal Cord Injury. Journal of Neuroscience. 33(2). 652–664. 44 indexed citations

14.

Montrose, David C., Xi Kathy Zhou, Levy Kopelovich, et al.. (2012). Metabolic Profiling, a Noninvasive Approach for the Detection of Experimental Colorectal Neoplasia. Cancer Prevention Research. 5(12). 1358–1367. 44 indexed citations

15.

Quijano, Celia, Liu Cao, Marı́a M. Fergusson, et al.. (2012). Oncogene-induced senescence results in marked metabolic and bioenergetic alterations. Cell Cycle. 11(7). 1383–1392. 116 indexed citations

16.

Reitman, Zachary J., Genglin Jin, Edward D. Karoly, et al.. (2011). Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proceedings of the National Academy of Sciences. 108(8). 3270–3275. 359 indexed citations

17.

Huang, Yuh‐Chin T., Edward D. Karoly, Lisa A. Dailey, et al.. (2011). Comparison of Gene Expression Profiles Induced By Coarse, Fine, and Ultrafine Particulate Matter. Journal of Toxicology and Environmental Health. 74(5). 296–312. 51 indexed citations

18.

Huang, Yuh‐Chin T., et al.. (2008). Identification of gene biomarkers for respiratory syncytial virus infection in a bronchial epithelial cell line. PubMed. 2(3-4). 113–125. 34 indexed citations

19.

Kodavanti, Urmila P., Mette C. Schladweiler, A. D. Ledbetter, et al.. (2006). The Spontaneously Hypertensive Rat: An Experimental Model of Sulfur Dioxide-Induced Airways Disease. Toxicological Sciences. 94(1). 193–205. 24 indexed citations

20.

Karoly, Edward D., Judith E. Schmid, & E. Sidney Hunter. (2004). Ontogeny of transcription profiles during mouse early craniofacial development. Reproductive Toxicology. 19(3). 339–352. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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