Eduardo Howard

1.7k citations

41 papers · 1.4k · h-index 19

Impact in

Physical and Theoretical Chemistry top 5%
- Crystallography and molecular interactions
Behavioral Neuroscience top 10%
- Stress Responses and Cortisol

Papers in

Molecular Biology 22
- Protein Structure and Dynamics 9
Materials Chemistry 13
- Enzyme Structure and Function 12

Co-authors: A. Podjarny (26 shared papers)J. Raúl Grigera (8 shared papers)A. Mitschler (18 shared papers)Patrick Barth (6 shared papers)Bernard Chevrier (7 shared papers)M. Van Zandt (5 shared papers)Valérie Lamour (6 shared papers)Raúl E. Cachau (5 shared papers)
Journals: Proteins Structure Function and Bioinformatics (4 papers)Scientific Reports (2 papers)Carbohydrate Research (2 papers)Journal of Medicinal Chemistry (2 papers)IUCrJ (1 paper)
Partner nations: France Argentina United States

In The Last Decade

Eduardo Howard

39 papers receiving 1.4k citations

Peers

Countries citing papers authored by Eduardo Howard

Since Specialization

Citations

This map shows the geographic impact of Eduardo Howard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eduardo Howard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eduardo Howard more than expected).

Fields of papers citing papers by Eduardo Howard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eduardo Howard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eduardo Howard. The network helps show where Eduardo Howard may publish in the future.

Co-authors

The 25 scholars most cited alongside Eduardo Howard, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Eduardo Howard Line = papers co-authored together Eduardo Howard links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 41 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å Proteins Structure Function and Bioinformatics ·Eduardo Howard, Ruslan Sanishvili, Raúl E. Cachau, A. Mitschler, Bernard Chevrier, Patrick Barth, Valérie Lamour, M. Van Zandt, E. Sibley, Cécile Bon, Dino Moras, T. Schneider, A. Joachimiak, A. Podjarny	2004	270
2	Interaction of water with α,α-trehalose in solution: molecular dynamics simulation approach Journal of the Chemical Society Faraday Transactions ·Marǐa C. Donnamarǐa, Eduardo Howard, J. Raúl Grigera	1994	113
3	Glial cells express both mineralocorticoid and glucocorticoid receptors The Journal of Steroid Biochemistry and Molecular Biology ·Martha C. Bohn, Eduardo Howard, Ursula Vielkind, Zygmunt S. Krozowski	1991	103
4	Electrostatic complementarity in an aldose reductase complex from ultra-high-resolution crystallography and first-principles calculations Proceedings of the National Academy of Sciences ·N. Muzet, Benoît Guillot, Christian Jelsch, Eduardo Howard, Claude Lecomte	2003	93
5	Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies Journal of the American Society for Mass Spectrometry ·Hélène Rogniaux, Alain Van Dorsselaer, Patrick Barth, J.F. Biellmann, J. Barbanton, M. Van Zandt, Bernard Chevrier, Eduardo Howard, A. Mitschler, Noëlle Potier, Ludmila Urzhumtseva, D. Moras, A. Podjarny	1999	86
6	Neutron macromolecular crystallography with LADI-III Acta Crystallographica Section D Biological Crystallography ·Matthew P. Blakeley, Susana C. M. Teixeira, I. Petit-Haertlein, Isabelle Hazemann, A. Mitschler, Michael Haertlein, Eduardo Howard, A. Podjarny	2010	71
7	The effect of stereochemistry upon carbohydrate hydration. A molecular dynamics simulation of β-d-galactopyranose and (α,β)-d-talopyranose Carbohydrate Research ·Saskia A. Galema, Eduardo Howard, Jan B. F. N. Engberts, J. Raúl Grigera	1994	70
8	Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury Journal of Medicinal Chemistry ·M.C. Van Zandt, Darren L. Whitehouse, Adam Gołȩbiowski, Min Koo Ji, Mingbao Zhang, R. Paul Beckett, G. Erik Jagdmann, Todd R. Ryder, Ryan Sheeler, Monica Andreoli, Barbara R. Conway, Keyvan Mahboubi, Gerard D’Angelo, A. Mitschler, A. Cousido-Siah, Francesc X. Ruiz, Eduardo Howard, A. Podjarny, Hagen Schroeter	2013	67
9	Neutron structure of type‐III antifreeze protein allows the reconstruction of AFP–ice interface Journal of Molecular Recognition ·Eduardo Howard, Matthew P. Blakeley, Michael Haertlein, I. Haertlein, A. Mitschler, Stuart Fisher, A. Cousido-Siah, Andrés G. Salvay, А. Н. Попов, Christoph Muller‐ Dieckmann, T. Petrova, A. Podjarny	2011	59
10	Structural Basis of Outstanding Multivalent Effects in Jack Bean α‐Mannosidase Inhibition Angewandte Chemie International Edition ·Eduardo Howard, A. Cousido-Siah, Mathieu L. Lepage, Jérémy P. Schneider, Anne Bodlenner, A. Mitschler, Alessandra Meli, Irene Izzo, H. Ariel Alvarez, A. Podjarny, Philippe Compain	2018	47
11	Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications Bioorganic & Medicinal Chemistry ·M.C. Van Zandt, E. Sibley, Erin E. McCann, Kerry J. Combs, Brenda R. Flam, Diane R. Sawicki, Al Sabetta, Anne L. Carrington, Janet Sredy, Eduardo Howard, A. Mitschler, A. Podjarny	2004	44
12	The structure of human aldose reductase bound to the inhibitor IDD384 Acta Crystallographica Section D Biological Crystallography ·V. Calderone, Bernard Chevrier, M. Van Zandt, Valérie Lamour, Eduardo Howard, Arnaud Poterszman, Patrick Barth, A. Mitschler, Jianhui Lu, D. Dvornik, G. Klebe, Oliver Kraemer, Allan R. Moorman, Dino Moras, A. Podjarny	2000	33
13	Production of crystals of human aldose reductase with very high resolution diffraction Acta Crystallographica Section D Biological Crystallography ·Valérie Lamour, Patrick Barth, Hélène Rogniaux, Arnaud Poterszman, Eduardo Howard, A. Mitschler, Alain Van Dorsselaer, A. Podjarny, Dino Moras	1999	29
14	High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP–oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution IUCrJ ·Eduardo Howard, Benoı̂t Guillot, Matthew P. Blakeley, Michael Haertlein, Martine Moulin, A. Mitschler, A. Cousido-Siah, Firas Fadel, Wanda M. Valsecchi, Takashi Tomizaki, T. Petrova, Julien Claudot, A. Podjarny	2016	26
15	Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain Scientific Reports ·Claire Bedez, Christophe Lotz, Claire Batisse, Arnaud Vanden Broeck, Roland H. Stote, Eduardo Howard, Karine Pradeau‐Aubreton, Marc Ruff, Valérie Lamour	2018	26
16	New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM Acta Crystallographica Section D Biological Crystallography ·Firas Fadel, Yuguang Zhao, Raúl E. Cachau, A. Cousido-Siah, Francesc X. Ruiz, Karl Harlos, Eduardo Howard, A. Mitschler, A. Podjarny	2015	26
17	Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II Journal of Medicinal Chemistry ·Michael C. Van Zandt, G. Erik Jagdmann, Darren L. Whitehouse, Minkoo Ji, Jennifer Savoy, Olga Potapova, A. Cousido-Siah, A. Mitschler, Eduardo Howard, Anna Marie Pyle, A. Podjarny	2019	24
18	Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography Acta Crystallographica Section D Biological Crystallography ·S. J. Fisher, Matthew P. Blakeley, Eduardo Howard, I. Petit-Haertlein, Michael Haertlein, A. Mitschler, A. Cousido-Siah, Andrés G. Salvay, А. Н. Попов, C. Muller-Dieckmann, T.S. Petrova, A. Podjarny	2014	21
19	Conformations of erythritol and L-threitol in aqueous solution in relation to sweetness properties: a molecular dynamics simulation Journal of the Chemical Society Faraday Transactions ·Eduardo Howard, J. Raúl Grigera	1992	19
20	Structure and Interactions of Fish Type III Antifreeze Protein in Solution Biophysical Journal ·Andrés G. Salvay, Frank Gabel, Bernard Pucci, Javier Santos, Eduardo Howard, Christine Ebel	2010	18

About Eduardo Howard

Eduardo Howard is a scholar working on Molecular Biology, Materials Chemistry, Cell Biology, Ecology and Organic Chemistry, having authored 41 papers that have together received 1.4k indexed citations. Recurring topics across this work include Enzyme Structure and Function (12 papers), Protein Structure and Dynamics (9 papers), Aldose Reductase and Taurine (9 papers), Physiological and biochemical adaptations (6 papers), Neonatal Health and Biochemistry (4 papers), Spectroscopy and Quantum Chemical Studies (4 papers), Biochemical Analysis and Sensing Techniques (3 papers) and Carbohydrate Chemistry and Synthesis (3 papers). The work is most often cited by research in Physical and Theoretical Chemistry (163 citations), Behavioral Neuroscience (61 citations), Cell Biology (222 citations), Filtration and Separation (25 citations) and Spectroscopy (184 citations). Eduardo Howard has collaborated with scholars based in France, Argentina and United States. Frequent co-authors include A. Podjarny, J. Raúl Grigera, A. Mitschler, Patrick Barth, Bernard Chevrier, M. Van Zandt, Valérie Lamour, Raúl E. Cachau, Dino Moras and Martha C. Bohn. Their work appears in journals such as Proteins Structure Function and Bioinformatics, Scientific Reports, Carbohydrate Research, Journal of Medicinal Chemistry and IUCrJ.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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