Debra F. Higgins

2.7k total citations · 1 hit paper
18 papers, 2.3k citations indexed

About

Debra F. Higgins is a scholar working on Molecular Biology, Cancer Research and Nephrology. According to data from OpenAlex, Debra F. Higgins has authored 18 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 8 papers in Cancer Research and 5 papers in Nephrology. Recurrent topics in Debra F. Higgins's work include Cancer, Hypoxia, and Metabolism (7 papers), Renal and related cancers (4 papers) and Connective Tissue Growth Factor Research (3 papers). Debra F. Higgins is often cited by papers focused on Cancer, Hypoxia, and Metabolism (7 papers), Renal and related cancers (4 papers) and Connective Tissue Growth Factor Research (3 papers). Debra F. Higgins collaborates with scholars based in Ireland, United States and United Kingdom. Debra F. Higgins's co-authors include Volker H. Haase, Randall S. Johnson, Yasuhiro Akai, Kuniko Kimura, Masayuki Iwano, Matthias Kretzler, Yoshihiko Saito, Kai-Uwe Eckardt, Wanja M. Bernhardt and Bernd Hohenstein and has published in prestigious journals such as Journal of Clinical Investigation, Molecular and Cellular Biology and Development.

In The Last Decade

Debra F. Higgins

18 papers receiving 2.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

2007 828 citations Debra F. Higgins, Kuniko Kimura et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Debra F. Higgins Ireland	16	1.1k	771	430	373	243	18	2.3k
Bernd Klanke Germany	25	692 0.6×	412 0.5×	322 0.7×	213 0.6×	179 0.7×	40	1.7k
Wanja M. Bernhardt Germany	23	1.2k 1.1×	1.3k 1.6×	504 1.2×	350 0.9×	311 1.3×	37	2.9k
Samir S. El‐Dahr United States	33	1.7k 1.6×	185 0.2×	332 0.8×	542 1.5×	169 0.7×	127	3.2k
Gunnar Schley Germany	25	937 0.9×	370 0.5×	242 0.6×	274 0.7×	106 0.4×	66	1.8k
Shiren Sun China	27	2.0k 1.8×	1.5k 1.9×	356 0.8×	298 0.8×	246 1.0×	49	3.0k
Ri‐Ning Tang China	24	1.5k 1.3×	560 0.7×	755 1.8×	235 0.6×	253 1.0×	70	2.4k
Rohan Samarakoon United States	28	1.2k 1.1×	490 0.6×	404 0.9×	366 1.0×	194 0.8×	47	2.4k
Hyun Mi Kang South Korea	14	1.2k 1.1×	265 0.3×	822 1.9×	220 0.6×	493 2.0×	35	2.7k
Bo Young Nam South Korea	20	528 0.5×	259 0.3×	548 1.3×	268 0.7×	182 0.7×	34	1.3k
Shotaro Naito Japan	24	896 0.8×	370 0.5×	271 0.6×	456 1.2×	302 1.2×	82	2.1k

Countries citing papers authored by Debra F. Higgins

Since Specialization

Citations

This map shows the geographic impact of Debra F. Higgins's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Debra F. Higgins with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Debra F. Higgins more than expected).

Fields of papers citing papers by Debra F. Higgins

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Debra F. Higgins. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Debra F. Higgins. The network helps show where Debra F. Higgins may publish in the future.

Co-authorship network of co-authors of Debra F. Higgins

This figure shows the co-authorship network connecting the top 25 collaborators of Debra F. Higgins. A scholar is included among the top collaborators of Debra F. Higgins based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Debra F. Higgins. Debra F. Higgins is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Krzyzanowska, Agnieszka, Stephen Barron, Debra F. Higgins, et al.. (2023). Development, Validation, and Clinical Utility of a Six-gene Signature to Predict Aggressive Prostate Cancer. European Urology Focus. 9(6). 983–991. 1 indexed citations

Higgins, Debra F., Claudia Mazo, William Watson, et al.. (2021). Future of biomarker evaluation in the realm of artificial intelligence algorithms: application in improved therapeutic stratification of patients with breast and prostate cancer. Journal of Clinical Pathology. 74(7). 429–434. 27 indexed citations

Griffin, Brenda Walker, et al.. (2017). Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863(4). 896–906. 12 indexed citations

Higgins, Debra F., et al.. (2017). BMP7-induced-Pten inhibits Akt and prevents renal fibrosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863(12). 3095–3104. 57 indexed citations

Andrews, Darrell, Martin Parsons, Mary Murphy, et al.. (2016). Wnt6 regulates epithelial cell differentiation and is dysregulated in renal fibrosis. American Journal of Physiology-Renal Physiology. 311(1). F35–F45. 24 indexed citations

Scully, Deirdre, et al.. (2016). Hypoxia promotes production of neural crest cells in the embryonic head. Development. 143(10). 1742–1752. 33 indexed citations

Griffin, Brenda Walker, Emma Börgeson, Fionnuala B. Hickey, et al.. (2013). IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833(8). 1969–1978. 17 indexed citations

Brennan, Eoin, Karen A. Nolan, Emma Börgeson, et al.. (2013). Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGFβR1. Journal of the American Society of Nephrology. 24(4). 627–637. 138 indexed citations

Börgeson, Emma, Fiona C. McGillicuddy, Karen A. Harford, et al.. (2012). Lipoxin A ₄ attenuates adipose inflammation. The FASEB Journal. 26(10). 4287–4294. 88 indexed citations

10.

Börgeson, Emma, Neil G. Docherty, Madeline Murphy, et al.. (2011). Lipoxin A ₄ and benzo‐lipoxin A ₄ attenuate experimental renal fibrosis. The FASEB Journal. 25(9). 2967–2979. 94 indexed citations

11.

Kimura, Kuniko, Masayuki Iwano, Debra F. Higgins, et al.. (2008). Stable expression of HIF-1α in tubular epithelial cells promotes interstitial fibrosis. American Journal of Physiology-Renal Physiology. 295(4). F1023–F1029. 228 indexed citations

12.

Higgins, Debra F., Kuniko Kimura, Masayuki Iwano, & Volker H. Haase. (2008). Hypoxia-inducible factor signaling in the development of tissue fibrosis. Cell Cycle. 7(9). 1128–1132. 157 indexed citations

13.

Higgins, Debra F., Kuniko Kimura, Wanja M. Bernhardt, et al.. (2007). Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. Journal of Clinical Investigation. 117(12). 3810–20. 828 indexed citations breakdown →

14.

Rankin, Erinn B., Debra F. Higgins, Jacqueline A. Walisser, et al.. (2005). Inactivation of the Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Suppresses von Hippel-Lindau Disease-Associated Vascular Tumors in Mice. Molecular and Cellular Biology. 25(8). 3163–3172. 122 indexed citations

15.

Higgins, Debra F., Mangatt P. Biju, Yasuhiro Akai, et al.. (2004). Hypoxic induction ofCtgfis directly mediated by Hif-1. American Journal of Physiology-Renal Physiology. 287(6). F1223–F1232. 238 indexed citations

16.

Power, Richard, et al.. (2004). Mechanical Deformation Induced Apoptosis in Human Proximal Renal Tubular Epithelial Cells is Caspase Dependent. The Journal of Urology. 171(1). 457–461. 36 indexed citations

17.

Kieran, Niamh E., Peter Doran, Susan Connolly, et al.. (2003). Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog. Kidney International. 64(2). 480–492. 129 indexed citations

18.

Higgins, Debra F., David Lappin, Niamh E. Kieran, et al.. (2003). DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): Modulation during epithelial-mesenchymal transition. Kidney International. 64(6). 2079–2091. 43 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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