David W. Meek

9.2k total citations · 1 hit paper
86 papers, 7.6k citations indexed

About

David W. Meek is a scholar working on Oncology, Molecular Biology and Biotechnology. According to data from OpenAlex, David W. Meek has authored 86 papers receiving a total of 7.6k indexed citations (citations by other indexed papers that have themselves been cited), including 73 papers in Oncology, 58 papers in Molecular Biology and 20 papers in Biotechnology. Recurrent topics in David W. Meek's work include Cancer-related Molecular Pathways (70 papers), Ubiquitin and proteasome pathways (26 papers) and Cancer Research and Treatments (20 papers). David W. Meek is often cited by papers focused on Cancer-related Molecular Pathways (70 papers), Ubiquitin and proteasome pathways (26 papers) and Cancer Research and Treatments (20 papers). David W. Meek collaborates with scholars based in United Kingdom, United States and Denmark. David W. Meek's co-authors include Diane Milne, Ted R. Hupp, David P. Lane, Carol Midgley, Carl W. Anderson, Uwe Knippschild, Walter Eckhart, David G. Campbell, Lynnette Marcar and Jayne Loughery and has published in prestigious journals such as Cell, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

David W. Meek

84 papers receiving 7.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of the specific DNA binding function of p53

1992 800 citations Ted R. Hupp, David W. Meek et al. profile →

Peers

David W. Meek

ONCOL

BIOTE

Sheau-Yann Shieh Taiwan

Takashi Tokino Japan

Ada Sacchi Italy

Christine E. Canman United States

Sandy Chang United States

Jean‐Christophe Bourdon United Kingdom

Fred Bunz United States

Galina Selivanova Sweden

Ruth Maya Israel

Hideyo Yasuda Japan

Sheau-Yann Shieh Taiwan

David W. Meek

6.2k ×1.1

4.6k ×1.1

ONCOL

1.3k ×1.0

1.1k ×1.1

774 ×0.9

BIOTE

Citations per year, relative to David W. Meek David W. Meek (= 1×) peers Sheau-Yann Shieh

Countries citing papers authored by David W. Meek

Since Specialization

Citations

This map shows the geographic impact of David W. Meek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David W. Meek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David W. Meek more than expected).

Fields of papers citing papers by David W. Meek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David W. Meek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David W. Meek. The network helps show where David W. Meek may publish in the future.

Co-authorship network of co-authors of David W. Meek

This figure shows the co-authorship network connecting the top 25 collaborators of David W. Meek. A scholar is included among the top collaborators of David W. Meek based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David W. Meek. David W. Meek is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Meek, David W., et al.. (2021). Detection of Post-translationally Modified p53 by Western Blotting. Methods in molecular biology. 2267. 7–18. 1 indexed citations

Marcar, Lynnette, John M Hourihan, Susan E. Bray, et al.. (2015). MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4. PLoS ONE. 10(5). e0127713–e0127713. 38 indexed citations

Meek, David W. & Lynnette Marcar. (2012). MAGE-A antigens as targets in tumour therapy. Cancer Letters. 324(2). 126–132. 73 indexed citations

Purdie, Colin A., Susan E. Bray, Philip Quinlan, et al.. (2012). Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53mutation and poor clinical outcome. Breast Cancer Research. 14(2). R40–R40. 82 indexed citations

Marcar, Lynnette, Nicola J. MacLaine, Ted R. Hupp, & David W. Meek. (2010). Mage-A Cancer/Testis Antigens Inhibit p53 Function by Blocking Its Interaction with Chromatin. Cancer Research. 70(24). 10362–10370. 127 indexed citations

Lai, Keng Po, Wai Fook Leong, Jenny Fung Ling Chau, et al.. (2010). S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response. The EMBO Journal. 29(17). 2994–3006. 99 indexed citations

Marcar, Lynnette, et al.. (2010). p53-dependent repression of polo-like kinase-1 (PLK1). Cell Cycle. 9(20). 4200–4212. 98 indexed citations

Meek, David W. & Ted R. Hupp. (2009). The regulation of MDM2 by multisite phosphorylation—Opportunities for molecular-based intervention to target tumours?. Seminars in Cancer Biology. 20(1). 19–28. 61 indexed citations

Nicol, Samantha M., Nerea Allende-Vega, Lynnette Marcar, et al.. (2009). FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53. FEBS Letters. 583(4). 621–626. 57 indexed citations

10.

Wood, Nicola T., David W. Meek, & Carol MacKintosh. (2009). 14‐3‐3 Binding to Pim‐phosphorylated Ser166 and Ser186 of human Mdm2 – Potential interplay with the PKB/Akt pathway and p14^ARF. FEBS Letters. 583(4). 615–620. 18 indexed citations

11.

Allende-Vega, Nerea, et al.. (2008). Transcription factor TAFII250 phosphorylates the acidic domain of Mdm2 through recruitment of protein kinase CK2. Molecular and Cellular Biochemistry. 316(1-2). 99–106. 8 indexed citations

12.

Marcar, Lynnette, Diane Milne, Mark K. Saville, et al.. (2008). Elevated Levels of Oncogenic Protein Kinase Pim-1 Induce the p53 Pathway in Cultured Cells and Correlate with Increased Mdm2 in Mantle Cell Lymphoma. Journal of Biological Chemistry. 283(26). 18012–18023. 71 indexed citations

13.

MacLaine, Nicola J., Bodil Øster, Jennifer A. Fraser, et al.. (2008). A Central Role for CK1 in Catalyzing Phosphorylation of the p53 Transactivation Domain at Serine 20 after HHV-6B Viral Infection. Journal of Biological Chemistry. 283(42). 28563–28573. 37 indexed citations

14.

Bjørling-Poulsen, Marina, et al.. (2005). The ‘regulatory’ β-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation. Oncogene. 24(40). 6194–6200. 13 indexed citations

15.

Kurki, Sari, Karita Peltonen, Leena Latonen, et al.. (2004). Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation. Cancer Cell. 5(5). 465–475. 347 indexed citations

16.

Milne, Diane, et al.. (2001). Catalytic Activity of Protein Kinase CK1δ (Casein Kinase 1δ) Is Essential for Its Normal Subcellular Localization. Experimental Cell Research. 263(1). 43–54. 63 indexed citations

17.

Jardine, Lesley, Diane Milne, Nicolas Dumaz, & David W. Meek. (1999). Phosphorylation of murine p53, but not human p53, by MAP kinase in vitro and in cultured cells highlights species-dependent variation in post-translational modification. Oncogene. 18(52). 7602–7607. 9 indexed citations

18.

Meek, David W.. (1999). Mechanisms of switching on p53: a role for covalent modification?. Oncogene. 18(53). 7666–7675. 198 indexed citations

19.

Meek, David W.. (1998). New developments in the multi-site phosphorylation and integration of stress signalling at p53. International Journal of Radiation Biology. 74(6). 729–737. 28 indexed citations

20.

Landesman, Yosef, et al.. (1997). Modifications of p53 Protein and Accumulation of p21 and gadd45 mRNA in TGF-β1 Growth Inhibited Cells. Cellular Signalling. 9(3-4). 291–298. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact