David Shugar

14.1k total citations · 2 hit papers
436 papers, 11.6k citations indexed

About

David Shugar is a scholar working on Molecular Biology, Organic Chemistry and Infectious Diseases. According to data from OpenAlex, David Shugar has authored 436 papers receiving a total of 11.6k indexed citations (citations by other indexed papers that have themselves been cited), including 292 papers in Molecular Biology, 129 papers in Organic Chemistry and 73 papers in Infectious Diseases. Recurrent topics in David Shugar's work include Biochemical and Molecular Research (128 papers), DNA and Nucleic Acid Chemistry (100 papers) and HIV/AIDS drug development and treatment (72 papers). David Shugar is often cited by papers focused on Biochemical and Molecular Research (128 papers), DNA and Nucleic Acid Chemistry (100 papers) and HIV/AIDS drug development and treatment (72 papers). David Shugar collaborates with scholars based in Poland, Slovakia and Belgium. David Shugar's co-authors include Agnieszka Bzowska, Jack J. Fox, Ewa Kulikowska, Erik De Clercq, Jan Antosiewicz, Borys Kierdaszuk, Halina Sierakowska, Zygmunt Kazimierczuk, Ryszard Stolarski and Paul F. Torrence and has published in prestigious journals such as Nature, Science and Journal of the American Chemical Society.

In The Last Decade

David Shugar

431 papers receiving 10.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme

1952 1.0k citations David Shugar profile →
Comparative Efficacy of Antiherpes Drugs against Different Strains of Herpes Simplex Virus

1980 552 citations David Shugar et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David Shugar Poland	48	7.7k	2.4k	1.5k	1.4k	1.1k	436	11.6k
Roland K. Robins United States	57	7.6k 1.0×	6.9k 2.9×	2.2k 1.4×	2.8k 2.0×	489 0.5×	466	14.3k
Robert Bittman United States	67	11.3k 1.5×	2.7k 1.1×	1.1k 0.7×	916 0.7×	677 0.6×	380	16.0k
Vern L. Schramm United States	63	9.9k 1.3×	2.0k 0.8×	2.6k 1.7×	2.2k 1.6×	1.6k 1.5×	354	14.0k
Richard Wolfenden United States	55	9.4k 1.2×	2.2k 0.9×	409 0.3×	504 0.4×	2.6k 2.4×	189	12.5k
G. Michael Blackburn United Kingdom	45	4.3k 0.6×	2.3k 0.9×	785 0.5×	353 0.3×	776 0.7×	242	7.7k
Richard M. Epand Canada	78	19.2k 2.5×	2.8k 1.2×	1.5k 1.0×	810 0.6×	776 0.7×	541	25.4k
Peter Reichard Sweden	74	12.4k 1.6×	782 0.3×	967 0.6×	1.0k 0.7×	1.8k 1.6×	231	16.9k
Shinichi Kondo Japan	56	6.5k 0.8×	2.8k 1.2×	1.7k 1.1×	347 0.3×	1.7k 1.6×	548	13.9k
L. Mario Amzel United States	70	9.7k 1.3×	1.5k 0.6×	503 0.3×	521 0.4×	1.7k 1.5×	246	14.7k
Alan C. Sartorelli United States	59	8.5k 1.1×	3.1k 1.3×	807 0.5×	726 0.5×	504 0.5×	514	15.9k

Countries citing papers authored by David Shugar

Since Specialization

Citations

This map shows the geographic impact of David Shugar's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Shugar with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Shugar more than expected).

Fields of papers citing papers by David Shugar

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Shugar. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Shugar. The network helps show where David Shugar may publish in the future.

Co-authorship network of co-authors of David Shugar

This figure shows the co-authorship network connecting the top 25 collaborators of David Shugar. A scholar is included among the top collaborators of David Shugar based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Shugar. David Shugar is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wierzchowski, Jacek, Jan Antosiewicz, & David Shugar. (2014). 8-Azapurines as isosteric purine fluorescent probes for nucleic acid and enzymatic research. Molecular BioSystems. 10(11). 2756–2774. 41 indexed citations

Poznański, Jarosław, Anna Poznańska, & David Shugar. (2014). A Protein Data Bank Survey Reveals Shortening of Intermolecular Hydrogen Bonds in Ligand-Protein Complexes When a Halogenated Ligand Is an H-Bond Donor. PLoS ONE. 9(6). e99984–e99984. 16 indexed citations

Wielechowska, Monika, et al.. (2014). Thermodynamic parameters for binding of some halogenated inhibitors of human protein kinase CK2. Biochemical and Biophysical Research Communications. 456(1). 282–287. 16 indexed citations

Antosiewicz, Jan & David Shugar. (2011). Poisson–Boltzmann continuum-solvation models: applications to pH-dependent properties of biomolecules. Molecular BioSystems. 7(11). 2923–2949. 18 indexed citations

Bretner, Maria, et al.. (2003). Selectivity of 4,5,6,7-tetrabromobenzimidazole [TBBZ] as an ATP-competitive potent inhibitor of protein kinase CK2 from various sources. Cellular & Molecular Biology Letters. 8. 6 indexed citations

Wielgus‐Kutrowska, Beata, Agnieszka Bzowska, Jan Tebbe, Gertraud Koellner, & David Shugar. (2002). Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation of the enzyme. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1597(2). 320–334. 19 indexed citations

Bzowska, Agnieszka, Ewa Kulikowska, & David Shugar. (2000). Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Pharmacology & Therapeutics. 88(3). 349–425. 403 indexed citations

Tebbe, Jan, Agnieszka Bzowska, Beata Wielgus‐Kutrowska, et al.. (1999). Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs. Journal of Molecular Biology. 294(5). 1239–1255. 56 indexed citations

Kierdaszuk, Borys, Krzysztof Krawiec, Zygmunt Kazimierczuk, et al.. (1998). Substrate/Inhibitor Specificities of Human Deoxycytidine Kinase (DCK) and Thymidine Kinases (TK1 and TK2). Advances in experimental medicine and biology. 431. 623–627. 5 indexed citations

10.

Koellner, Gertraud, Marija Luić, David Shugar, Wolfram Saenger, & Agnieszka Bzowska. (1997). Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 Å resolution. Journal of Molecular Biology. 265(2). 202–216. 74 indexed citations

11.

Weekes, John, Simon A. Hawley, Julia M. Corton, David Shugar, & D. Grahame Hardie. (1994). Activation of rat liver AMP‐activated protein kinase by kinase kinase in a purified, reconstituted system. European Journal of Biochemistry. 219(3). 751–757. 67 indexed citations

12.

Bzowska, Agnieszka, et al.. (1991). Acyclonucleoside analogue inhibitors of mammalian purine nucleoside phosphorylase. Biochemical Pharmacology. 41(12). 1791–1803. 29 indexed citations

13.

Stolarski, Ryszard, et al.. (1984). Studies on the dynamic syn‐anti equilibrium in purine nucleosides and nucleotides with the aid of ¹H and ¹³C NMR spectroscopy. European Journal of Biochemistry. 138(1). 187–192. 37 indexed citations

14.

Shugar, David, et al.. (1983). Obituary: Professor Michael Laskowski Sr.. PubMed. 30(2). 113–4. 1 indexed citations

15.

Sierakowska, Halina & David Shugar. (1977). Mammalian Nucleolytic Enzymes. Progress in nucleic acid research and molecular biology. 20. 59–130. 105 indexed citations

16.

Fikus, M, et al.. (1974). Biochemical studies on some new analogues of adenosine-3'5'-cyclic phosphate, including isoguanosine-3 ,5-cylic phosphate.. PubMed. 21(4). 465–74. 3 indexed citations

17.

Shugar, David, et al.. (1972). Radio-products of Thymine in the Presence of Ethanol. International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine. 21(2). 101–114. 6 indexed citations

18.

Shugar, David. (1969). Biochemical aspects of antimetabolites and of drug hydroxylation. Academic Press eBooks. 37 indexed citations

19.

Szer, W., et al.. (1965). Some properties of poly-ribothymidylic acid, co-polymers of uridylic and ribothymidylic acids, and their 1:1 complexes with polyadenylic acid.. PubMed. 342(4). 429–36. 1 indexed citations

20.

Janion, Celina & David Shugar. (1965). Reaction of hydroxylamine with 5-substituted cytosines. Biochemical and Biophysical Research Communications. 18(4). 617–622. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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