Constanze Hilgendorf

3.5k total citations
40 papers, 2.6k citations indexed

About

Constanze Hilgendorf is a scholar working on Oncology, Molecular Biology and Pharmacology. According to data from OpenAlex, Constanze Hilgendorf has authored 40 papers receiving a total of 2.6k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Oncology, 13 papers in Molecular Biology and 11 papers in Pharmacology. Recurrent topics in Constanze Hilgendorf's work include Drug Transport and Resistance Mechanisms (27 papers), Pharmacogenetics and Drug Metabolism (11 papers) and Pharmacological Effects and Toxicity Studies (8 papers). Constanze Hilgendorf is often cited by papers focused on Drug Transport and Resistance Mechanisms (27 papers), Pharmacogenetics and Drug Metabolism (11 papers) and Pharmacological Effects and Toxicity Studies (8 papers). Constanze Hilgendorf collaborates with scholars based in Sweden, United Kingdom and United States. Constanze Hilgendorf's co-authors include Anna‐Lena Ungell, Per Artursson, Annick Seithel, Johan Karlsson, Peter Langguth, Gustav Ahlin, C G Regårdh, Hildegard Spahn‐Langguth, Gordon L. Amidon and Elke Lipka and has published in prestigious journals such as Scientific Reports, Journal of Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

In The Last Decade

Constanze Hilgendorf

39 papers receiving 2.5k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Constanze Hilgendorf Sweden	22	1.3k	800	550	497	361	40	2.6k
Ayman El‐Kattan United States	33	1.3k 1.0×	697 0.9×	666 1.2×	1.0k 2.1×	577 1.6×	53	3.2k
Anna‐Lena Ungell Sweden	32	1.7k 1.3×	863 1.1×	741 1.3×	628 1.3×	984 2.7×	57	3.9k
Praveen Balimane United States	21	952 0.7×	559 0.7×	380 0.7×	334 0.7×	299 0.8×	34	2.1k
Jan Snoeys Belgium	33	897 0.7×	1.2k 1.6×	451 0.8×	906 1.8×	187 0.5×	94	3.7k
Pär Matsson Sweden	24	1.3k 1.0×	1.1k 1.4×	590 1.1×	511 1.0×	173 0.5×	36	2.8k
Tycho Heimbach United States	28	618 0.5×	1.1k 1.3×	393 0.7×	613 1.2×	793 2.2×	70	3.4k
Sibylle Neuhoff United Kingdom	30	1.6k 1.2×	503 0.6×	794 1.4×	968 1.9×	404 1.1×	68	2.8k
Laurent Salphati United States	30	1.7k 1.3×	876 1.1×	777 1.4×	935 1.9×	206 0.6×	67	2.9k
Stefan Oswald Germany	35	2.0k 1.6×	687 0.9×	947 1.7×	955 1.9×	199 0.6×	117	3.8k
Masato Chiba Japan	35	1.7k 1.3×	1.1k 1.4×	519 0.9×	1.2k 2.3×	138 0.4×	114	3.7k

Countries citing papers authored by Constanze Hilgendorf

Since Specialization

Citations

This map shows the geographic impact of Constanze Hilgendorf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Constanze Hilgendorf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Constanze Hilgendorf more than expected).

Fields of papers citing papers by Constanze Hilgendorf

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Constanze Hilgendorf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Constanze Hilgendorf. The network helps show where Constanze Hilgendorf may publish in the future.

Co-authorship network of co-authors of Constanze Hilgendorf

This figure shows the co-authorship network connecting the top 25 collaborators of Constanze Hilgendorf. A scholar is included among the top collaborators of Constanze Hilgendorf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Constanze Hilgendorf. Constanze Hilgendorf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Argikar, Upendra A., et al.. (2025). Clinical Significance of Drug–Drug Interaction Studies During Therapeutic Peptide Drug Development: Follow‐Up Investigation of Therapeutic Peptides Approved Between 2021 and 2024. Clinical and Translational Science. 18(7). 1 indexed citations

Argikar, Upendra A., Kari R. Fonseca, Constanze Hilgendorf, et al.. (2023). Industry Perspective on Therapeutic Peptide Drug–Drug Interaction Assessments During Drug Development: A European Federation of Pharmaceutical Industries and Associations White Paper. Clinical Pharmacology & Therapeutics. 113(6). 1199–1216. 15 indexed citations

He, Minxia M., Xiaochun Zhu, Joe R. Cannon, et al.. (2023). Metabolism and Excretion of Therapeutic Peptides: Current Industry Practices, Perspectives, and Recommendations. Drug Metabolism and Disposition. 51(11). 1436–1450. 7 indexed citations

Vildhede, Anna, Tommy B. Andersson, Fredrik Erlandsson, et al.. (2021). In Vitro Assessment of the Drug–Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters. Journal of Pharmacology and Experimental Therapeutics. 378(2). 108–123. 3 indexed citations

Johansson, Susanne, David P. Rosenbaum, Johan Palm, et al.. (2017). Tenapanor administration and the activity of the H⁺‐coupled transporter PepT1 in healthy volunteers. British Journal of Clinical Pharmacology. 83(9). 2008–2014. 10 indexed citations

Winiwarter, Susanne, et al.. (2017). In Vitro Intrinsic Permeability: A Transporter-Independent Measure of Caco-2 Cell Permeability in Drug Design and Development. Molecular Pharmaceutics. 14(5). 1601–1609. 67 indexed citations

Nilsson, Anna, et al.. (2017). Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis. Scientific Reports. 7(1). 6352–6352. 24 indexed citations

Sjögren, Erik, et al.. (2016). Excised segments of rat small intestine in Ussing chamber studies: A comparison of native and stripped tissue viability and permeability to drugs. International Journal of Pharmaceutics. 505(1-2). 361–368. 26 indexed citations

Nieskens, Tom T.G., Janny G.P. Peters, Niels Smits, et al.. (2016). A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity. The AAPS Journal. 18(2). 465–475. 94 indexed citations

10.

Schophuizen, Carolien M. S., Martijn J. Wilmer, Jitske Jansen, et al.. (2013). Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter. Pflügers Archiv - European Journal of Physiology. 465(12). 1701–1714. 52 indexed citations

11.

Karlsson, Fredrik, et al.. (2013). Utility of In Vitro Systems and Preclinical Data for the Prediction of Human Intestinal First-Pass Metabolism during Drug Discovery and Preclinical Development. Drug Metabolism and Disposition. 41(12). 2033–2046. 31 indexed citations

12.

Hilgendorf, Constanze, et al.. (2012). Characterization of THLE-Cytochrome P450 (P450) Cell Lines: Gene Expression Background and Relationship to P450-Enzyme Activity. Drug Metabolism and Disposition. 40(11). 2054–2058. 15 indexed citations

13.

Hutter, Victoria, et al.. (2012). Evaluation of layers of the rat airway epithelial cell line RL-65 for permeability screening of inhaled drug candidates. European Journal of Pharmaceutical Sciences. 47(2). 481–489. 3 indexed citations

14.

Elsby, Robert, Constanze Hilgendorf, & Katherine S. Fenner. (2012). Understanding the Critical Disposition Pathways of Statins to Assess Drug–Drug Interaction Risk During Drug Development: It's Not Just About OATP1B1. Clinical Pharmacology & Therapeutics. 92(5). 584–598. 163 indexed citations

15.

Karlsson, Johan, et al.. (2010). High-Activity P-Glycoprotein, Multidrug Resistance Protein 2, and Breast Cancer Resistance Protein Membrane Vesicles Prepared from Transiently Transfected Human Embryonic Kidney 293-Epstein-Barr Virus Nuclear Antigen Cells. Drug Metabolism and Disposition. 38(4). 705–714. 23 indexed citations

16.

Ahlin, Gustav, Constanze Hilgendorf, Johan Karlsson, et al.. (2009). Endogenous Gene and Protein Expression of Drug-Transporting Proteins in Cell Lines Routinely Used in Drug Discovery Programs. Drug Metabolism and Disposition. 37(12). 2275–2283. 112 indexed citations

17.

Hilgendorf, Constanze, Gustav Ahlin, Annick Seithel, et al.. (2007). Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines. Drug Metabolism and Disposition. 35(8). 1333–1340. 457 indexed citations

18.

Seithel, Annick, et al.. (2006). Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells. European Journal of Pharmaceutical Sciences. 28(4). 291–299. 148 indexed citations

19.

Hilgendorf, Constanze, Hildegard Spahn‐Langguth, C G Regårdh, et al.. (2000). Caco‐2 versus Caco‐2/HT29‐MTX Co‐cultured Cell Lines: Permeabilities Via Diffusion, Inside‐ and Outside‐Directed Carrier‐Mediated Transport. Journal of Pharmaceutical Sciences. 89(1). 63–75. 366 indexed citations

20.

Anderle, Pascale, Eva Niederer, Werner Rubas, et al.. (1998). P-Glycoprotein (P-gp) Mediated Efflux in Caco-2 Cell Monolayers: The Influence of Culturing Conditions and Drug Exposure on P-gp Expression Levels. Journal of Pharmaceutical Sciences. 87(6). 757–762. 179 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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