Christopher U.T. Hellen

19.4k total citations · 4 hit papers
123 papers, 15.3k citations indexed

About

Christopher U.T. Hellen is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Plant Science. According to data from OpenAlex, Christopher U.T. Hellen has authored 123 papers receiving a total of 15.3k indexed citations (citations by other indexed papers that have themselves been cited), including 103 papers in Molecular Biology, 62 papers in Cardiology and Cardiovascular Medicine and 21 papers in Plant Science. Recurrent topics in Christopher U.T. Hellen's work include RNA and protein synthesis mechanisms (92 papers), Viral Infections and Immunology Research (62 papers) and RNA modifications and cancer (42 papers). Christopher U.T. Hellen is often cited by papers focused on RNA and protein synthesis mechanisms (92 papers), Viral Infections and Immunology Research (62 papers) and RNA modifications and cancer (42 papers). Christopher U.T. Hellen collaborates with scholars based in United States, Russia and United Kingdom. Christopher U.T. Hellen's co-authors include Tatyana V. Pestova, Richard J. Jackson, Eckard Wimmer, Peter Sarnow, Victoria Kolupaeva, Ivan B. Lomakin, Ivan N. Shatsky, Andrey V. Pisarev, Ivan N. Shatsky and Vera P. Pisareva and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Christopher U.T. Hellen

122 papers receiving 15.2k citations

Hit Papers

The mechanism of eukaryotic translation initiatio... 1998 2026 2007 2016 2010 2001 1998 2001 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The mechanism of eukaryotic translation initiation and principles of its regulation
    2010 2.0k citations Christopher U.T. Hellen, Tatyana V. Pestova et al. profile →
  2. Internal ribosome entry sites in eukaryotic mRNA molecules
    2001 799 citations Christopher U.T. Hellen et al. Genes & Development profile →
  3. A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs
    1998 607 citations Tatyana V. Pestova, Ivan N. Shatsky et al. Genes & Development profile →
  4. Molecular mechanisms of translation initiation in eukaryotes
    2001 604 citations Tatyana V. Pestova, Victoria Kolupaeva et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christopher U.T. Hellen United States 65 12.3k 5.8k 1.8k 1.7k 1.0k 123 15.3k
Tatyana V. Pestova United States 64 13.7k 1.1× 4.8k 0.8× 1.3k 0.7× 1.4k 0.8× 921 0.9× 112 15.8k
Peter Sarnow United States 65 12.8k 1.0× 4.5k 0.8× 1.8k 1.0× 1.5k 0.9× 2.0k 1.9× 129 17.4k
Bert L. Semler United States 52 4.2k 0.3× 5.3k 0.9× 2.9k 1.6× 1.4k 0.8× 852 0.8× 129 7.9k
Akio Nomoto Japan 56 4.8k 0.4× 4.8k 0.8× 3.2k 1.7× 1.3k 0.8× 1.3k 1.3× 176 10.6k
Karla Kirkegaard United States 52 4.3k 0.3× 3.3k 0.6× 2.5k 1.3× 1.5k 0.9× 1.2k 1.2× 94 9.4k
Yuri V. Svitkin Canada 47 6.9k 0.6× 2.7k 0.5× 980 0.5× 558 0.3× 603 0.6× 82 8.7k
Graham J. Belsham Denmark 58 5.4k 0.4× 6.4k 1.1× 2.0k 1.1× 817 0.5× 738 0.7× 228 11.8k
John W.B. Hershey United States 72 16.3k 1.3× 1.9k 0.3× 708 0.4× 949 0.6× 2.2k 2.2× 215 18.6k
Ming Luo United States 46 3.6k 0.3× 1.7k 0.3× 2.2k 1.2× 931 0.5× 1.3k 1.2× 203 8.5k
Michael B. Mathews United States 71 14.5k 1.2× 1.8k 0.3× 1.7k 0.9× 724 0.4× 4.6k 4.5× 195 19.1k

Countries citing papers authored by Christopher U.T. Hellen

Since Specialization
Citations

This map shows the geographic impact of Christopher U.T. Hellen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher U.T. Hellen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher U.T. Hellen more than expected).

Fields of papers citing papers by Christopher U.T. Hellen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher U.T. Hellen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher U.T. Hellen. The network helps show where Christopher U.T. Hellen may publish in the future.

Co-authorship network of co-authors of Christopher U.T. Hellen

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher U.T. Hellen. A scholar is included among the top collaborators of Christopher U.T. Hellen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher U.T. Hellen. Christopher U.T. Hellen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Hellen, Christopher U.T. & Tatyana V. Pestova. (2025). Superkiller complex problems expose a cancer-cell vulnerability. Nature. 638(8052). 897–899.
3.
Kuroha, Kazushige, et al.. (2024). Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC. Nucleic Acids Research. 52(8). 4627–4643. 10 indexed citations
4.
Pestova, Tatyana V., et al.. (2024). Translation of Overlapping Open Reading Frames Promoted by Type 2 IRESs in Avian Calicivirus Genomes. Viruses. 16(9). 1413–1413. 3 indexed citations
5.
Abaeva, Irina S., et al.. (2023). In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g. Genes & Development. 37(17-18). 844–860. 9 indexed citations
6.
7.
Abaeva, Irina S., et al.. (2023). The structure and mechanism of action of a distinct class of dicistrovirus intergenic region IRESs. Nucleic Acids Research. 51(17). 9294–9313. 6 indexed citations
8.
Abaeva, Irina S., et al.. (2022). Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. The EMBO Journal. 41(16). e110581–e110581. 23 indexed citations
9.
Pestova, Tatyana V., et al.. (2021). Horizontal gene transfer as a mechanism for the promiscuous acquisition of distinct classes of IRES by avian caliciviruses. Nucleic Acids Research. 50(2). 1052–1068. 10 indexed citations
10.
Sweeney, Trevor R., et al.. (2021). Functional role and ribosomal position of the unique N-terminal region of DHX29, a factor required for initiation on structured mammalian mRNAs. Nucleic Acids Research. 49(22). 12955–12969. 9 indexed citations
11.
Pisarev, Andrey V., Victoria Kolupaeva, Marat Yusupov, Christopher U.T. Hellen, & Tatyana V. Pestova. (2008). Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes. The EMBO Journal. 27(11). 1609–1621. 170 indexed citations
12.
Pisareva, Vera P., Andrey V. Pisarev, Anton A. Komar, Christopher U.T. Hellen, & Tatyana V. Pestova. (2008). Translation Initiation on Mammalian mRNAs with Structured 5′UTRs Requires DExH-Box Protein DHX29. Cell. 135(7). 1237–1250. 180 indexed citations
13.
Breyne, Sylvain de, et al.. (2008). Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases. Virology. 378(1). 118–122. 69 indexed citations
14.
15.
Pestova, Tatyana V., Jon R. Lorsch, & Christopher U.T. Hellen. (2007). 4 The Mechanism of Translation Initiation in Eukaryotes. Cold Spring Harbor Monograph Archive. 48. 87–128. 30 indexed citations
16.
Pisarev, Andrey V., Anett Unbehaun, Christopher U.T. Hellen, & Tatyana V. Pestova. (2007). Assembly and Analysis of Eukaryotic Translation Initiation Complexes. Methods in enzymology on CD-ROM/Methods in enzymology. 430. 147–177. 97 indexed citations
17.
Kolupaeva, Victoria, Ivan B. Lomakin, Tatyana V. Pestova, & Christopher U.T. Hellen. (2002). Eukaryotic Initiation Factors 4G and 4A Mediate Conformational Changes Downstream of the Initiation Codon of the Encephalomyocarditis Virus Internal Ribosomal Entry Site. Molecular and Cellular Biology. 23(2). 687–698. 85 indexed citations
18.
Kolupaeva, Victoria, Tatyana V. Pestova, Christopher U.T. Hellen, & Ivan N. Shatsky. (1998). Translation Eukaryotic Initiation Factor 4G Recognizes a Specific Structural Element within the Internal Ribosome Entry Site of Encephalomyocarditis Virus RNA. Journal of Biological Chemistry. 273(29). 18599–18604. 159 indexed citations
19.
Pestova, Tatyana V., Ivan N. Shatsky, & Christopher U.T. Hellen. (1996). Functional Dissection of Eukaryotic Initiation Factor 4F: the 4A Subunit and the Central Domain of the 4G Subunit Are Sufficient To Mediate Internal Entry of 43S Preinitiation Complexes. Molecular and Cellular Biology. 16(12). 6870–6878. 299 indexed citations
20.
Hellen, Christopher U.T. & Eckard Wimmer. (1992). The role of proteolytic processing in the morphogenesis of virus particles. Cellular and Molecular Life Sciences. 48(2). 201–215. 33 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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