Christopher U.T. Hellen

19.4k citations

123 papers · 15.3k indexed · 4 hit papers · h-index 65

Cardiology and Cardiovascular Medicine top 0.2%
- Viral Infections and Immunology Research 62
Molecular Biology top 0.2%
- RNA and protein synthesis mechanisms 92
- RNA modifications and cancer 42
- RNA Research and Splicing 40
- RNA regulation and disease 15
Infectious Diseases top 0.5%
- Viral gastroenteritis research and epidemiology 15
Hepatology top 1%
Animal Science and Zoology top 0.5%
Plant Science
- Plant Virus Research Studies 21
Ecology
- Bacteriophages and microbial interactions 9

Co-authors: Tatyana V. Pestova Richard J. Jackson Eckard Wimmer Peter Sarnow Victoria Kolupaeva Ivan B. Lomakin Ivan N. Shatsky Andrey V. Pisarev
Cited by: Cardiology and Cardiovascular Medicine Molecular Biology Infectious Diseases
Journals: Nucleic Acids Research (12 papers)Genes & Development (11 papers)Journal of Virology (11 papers)
Partner nations: United States Russia United Kingdom

In The Last Decade

Christopher U.T. Hellen

122 papers receiving 15.2k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2010 Nature Reviews Molecular Cell Biology
2001 Genes & Development
2001 Proceedings of the National Academy of Sciences
1998 Genes & Development

Peers

Countries citing papers authored by Christopher U.T. Hellen

Since Specialization

Citations

This map shows the geographic impact of Christopher U.T. Hellen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher U.T. Hellen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher U.T. Hellen more than expected).

Fields of papers citing papers by Christopher U.T. Hellen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher U.T. Hellen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher U.T. Hellen. The network helps show where Christopher U.T. Hellen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Christopher U.T. Hellen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher U.T. Hellen Line = papers co-authored together Christopher U.T. Hellen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin Genes & Development ·Irina S. Abaeva,Rozario Cyril,Christopher U.T. Hellen,Tatyana V. Pestova	2025	3
2	Superkiller complex problems expose a cancer-cell vulnerability Nature ·Christopher U.T. Hellen,Tatyana V. Pestova	2025	0
3	Translation of Overlapping Open Reading Frames Promoted by Type 2 IRESs in Avian Calicivirus Genomes Viruses ·高井則之,Tatyana V. Pestova,Christopher U.T. Hellen	2024	3
4	Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC Nucleic Acids Research ·M Huebner Gesche,Rozario Cyril,Kazushige Kuroha,Alexandra Zinoviev,Christopher U.T. Hellen,Tatyana V. Pestova	2024	10
5	Initiation of translation on nedicistrovirus and related intergenic region IRESs by their factor-independent binding to the P site of 80S ribosomes RNA ·M Huebner Gesche,Gabriela Parra,Irina S. Abaeva,Tatyana V. Pestova,Christopher U.T. Hellen	2023	6
6	The structure and mechanism of action of a distinct class of dicistrovirus intergenic region IRESs Nucleic Acids Research ·Irina S. Abaeva,Amir Reza Ghassami,郝如意,Erik Johannes Forsmo,Laurence Le Callonec,Eric Jan,Tatyana V. Pestova,Christopher U.T. Hellen	2023	6
7	In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g Genes & Development ·Irina S. Abaeva,高井則之,M Huebner Gesche,Christopher U.T. Hellen,Tatyana V. Pestova	2023	9
8	Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES The EMBO Journal ·T. Lampray,Irina S. Abaeva,Thomas Gichuru,Christopher U.T. Hellen,Tatyana V. Pestova,Joachim Frank	2022	23
9	Functional role and ribosomal position of the unique N-terminal region of DHX29, a factor required for initiation on structured mammalian mRNAs Nucleic Acids Research ·Trevor R. Sweeney,Vidya Dhote,Alfred Bonillo i Duran,Christopher U.T. Hellen,Yaser Hashem,Tatyana V. Pestova	2021	9
10	Horizontal gene transfer as a mechanism for the promiscuous acquisition of distinct classes of IRES by avian caliciviruses Nucleic Acids Research ·高井則之,M Huebner Gesche,Tatyana V. Pestova,Christopher U.T. Hellen	2021	10
11	Widespread distribution and structural diversity of Type IV IRESs in members of Picornaviridae Virology ·Mukta Asnani,Parimal Kumar,Christopher U.T. Hellen	2015	52
12	Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes The EMBO Journal ·Andrey V. Pisarev,Victoria Kolupaeva,Marat Yusupov,Christopher U.T. Hellen,Tatyana V. Pestova	2008	170
13	Translation Initiation on Mammalian mRNAs with Structured 5′UTRs Requires DExH-Box Protein DHX29 Cell ·Vera P. Pisareva,Andrey V. Pisarev,Anton A. Komar,Christopher U.T. Hellen,Tatyana V. Pestova	2008	180
14	Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases Virology ·Sylvain de Breyne,M.K. Iqbal,Konstantin Chumakov,Richard E. Lloyd,Christopher U.T. Hellen	2008	69
15	A Distinct Group of Hepacivirus/Pestivirus-Like Internal Ribosomal Entry Sites in Members of Diverse Picornavirus Genera: Evidence for Modular Exchange of Functional Noncoding RNA Elements by Recombination Journal of Virology ·Christopher U.T. Hellen,Sylvain de Breyne	2007	115
16	4 The Mechanism of Translation Initiation in Eukaryotes Cold Spring Harbor Monograph Archive ·Tatyana V. Pestova,Jon R. Lorsch,Christopher U.T. Hellen	2007	30
17	Assembly and Analysis of Eukaryotic Translation Initiation Complexes Methods in enzymology on CD-ROM/Methods in enzymology ·Andrey V. Pisarev,Anett Unbehaun,Christopher U.T. Hellen,Tatyana V. Pestova	2007	97
18	Eukaryotic Initiation Factors 4G and 4A Mediate Conformational Changes Downstream of the Initiation Codon of the Encephalomyocarditis Virus Internal Ribosomal Entry Site Molecular and Cellular Biology ·Victoria Kolupaeva,Ivan B. Lomakin,Tatyana V. Pestova,Christopher U.T. Hellen	2002	85
19	Functional Dissection of Eukaryotic Initiation Factor 4F: the 4A Subunit and the Central Domain of the 4G Subunit Are Sufficient To Mediate Internal Entry of 43S Preinitiation Complexes Molecular and Cellular Biology ·Tatyana V. Pestova,Ivan N. Shatsky,Christopher U.T. Hellen	1996	299
20	The role of proteolytic processing in the morphogenesis of virus particles Cellular and Molecular Life Sciences ·Christopher U.T. Hellen,Eckard Wimmer	1992	33

About Christopher U.T. Hellen

Christopher U.T. Hellen is a scholar working on Cardiology and Cardiovascular Medicine, Molecular Biology and Endocrinology, having authored 123 papers that have together received 15.3k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (92 papers), Viral Infections and Immunology Research (62 papers), RNA modifications and cancer (42 papers), RNA Research and Splicing (40 papers), Plant Virus Research Studies (21 papers), Viral gastroenteritis research and epidemiology (15 papers), RNA regulation and disease (15 papers) and Bacteriophages and microbial interactions (9 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (5.8k citations), Molecular Biology (12.3k citations) and Infectious Diseases (1.8k citations). Christopher U.T. Hellen has collaborated with scholars based in United States, Russia and United Kingdom. Frequent co-authors include Tatyana V. Pestova, Richard J. Jackson, Eckard Wimmer, Peter Sarnow, Victoria Kolupaeva, Ivan B. Lomakin, Ivan N. Shatsky, Andrey V. Pisarev, Ivan N. Shatsky and Vera P. Pisareva. Their work appears in journals such as Nucleic Acids Research, Genes & Development, Journal of Virology, The EMBO Journal and Molecular Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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