Charles Spruck

8.4k total citations · 2 hit papers
58 papers, 5.9k citations indexed

About

Charles Spruck is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Charles Spruck has authored 58 papers receiving a total of 5.9k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 28 papers in Oncology and 11 papers in Cell Biology. Recurrent topics in Charles Spruck's work include Cancer-related Molecular Pathways (24 papers), Epigenetics and DNA Methylation (14 papers) and Microtubule and mitosis dynamics (11 papers). Charles Spruck is often cited by papers focused on Cancer-related Molecular Pathways (24 papers), Epigenetics and DNA Methylation (14 papers) and Microtubule and mitosis dynamics (11 papers). Charles Spruck collaborates with scholars based in United States, Sweden and United Kingdom. Charles Spruck's co-authors include Kwang‐Ai Won, Steven I. Reed, Olle Sangfelt, Heimo Strohmaier, Peter A. Jones, Yvonne Tsai, Mirella Gonzalez‐Zulueta, Peter W. Nichols, David Esrig and William M. Rideout and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Charles Spruck

58 papers receiving 5.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Deregulated cyclin E induces chromosome instability

1999 564 citations Charles Spruck, Steven I. Reed et al. profile →
Triple‑negative breast cancer therapy: Current and future perspectives (Review)

2020 333 citations Charles Spruck et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Charles Spruck United States	36	4.0k	2.4k	1.1k	937	767	58	5.9k
Maria Flavia Di Renzo Italy	40	4.0k 1.0×	1.9k 0.8×	1.3k 1.2×	995 1.1×	545 0.7×	106	7.4k
Martina Olivero Italy	33	3.0k 0.8×	1.5k 0.6×	958 0.9×	813 0.9×	385 0.5×	80	5.6k
Susanne M. Gollin United States	48	4.4k 1.1×	2.0k 0.8×	649 0.6×	1.6k 1.7×	808 1.1×	141	7.2k
Martin van der Valk Netherlands	33	4.0k 1.0×	3.6k 1.5×	418 0.4×	703 0.8×	570 0.7×	45	6.9k
Martín E. Fernández-Zapico United States	47	5.0k 1.3×	3.0k 1.2×	854 0.8×	1.5k 1.6×	696 0.9×	172	7.7k
John P. Morris United States	25	4.2k 1.1×	2.8k 1.1×	905 0.8×	1.4k 1.5×	485 0.6×	36	6.6k
David W. Yandell United States	38	3.9k 1.0×	3.1k 1.3×	536 0.5×	1.2k 1.2×	388 0.5×	67	7.0k
Vundavalli V. Murty United States	40	4.4k 1.1×	1.9k 0.8×	631 0.6×	1.3k 1.4×	828 1.1×	109	7.2k
Michael T. Barrett United States	34	1.9k 0.5×	1.4k 0.6×	965 0.9×	1.1k 1.2×	295 0.4×	99	4.2k
Susan B. Olson United States	37	4.1k 1.0×	1.1k 0.5×	1.2k 1.1×	1.2k 1.3×	730 1.0×	112	6.5k

Countries citing papers authored by Charles Spruck

Since Specialization

Citations

This map shows the geographic impact of Charles Spruck's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles Spruck with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles Spruck more than expected).

Fields of papers citing papers by Charles Spruck

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles Spruck. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles Spruck. The network helps show where Charles Spruck may publish in the future.

Co-authorship network of co-authors of Charles Spruck

This figure shows the co-authorship network connecting the top 25 collaborators of Charles Spruck. A scholar is included among the top collaborators of Charles Spruck based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Charles Spruck. Charles Spruck is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Li, Chunying, Bihui Cao, Vo Van Giau, et al.. (2025). SUV39H1 maintains cancer stem cell chromatin state and properties in glioblastoma. JCI Insight. 10(5). 3 indexed citations

Spruck, Charles, et al.. (2024). Evolution of Repetitive Elements, Their Roles in Homeostasis and Human Disease, and Potential Therapeutic Applications. Biomolecules. 14(10). 1250–1250. 1 indexed citations

Rahmanto, Aldwin Suryo, Henrik J. Johansson, Marcela Franco, et al.. (2020). PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer. eLife. 9. 20 indexed citations

Shen, Jia, Zhixin Qiu, Qiulian Wu, et al.. (2020). FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell. 184(2). 352–369.e23. 72 indexed citations

Ellederová, Zdeňka, Sonia V. del Rincón, Andrej Šušor, et al.. (2019). CKS1 Germ Line Exclusion Is Essential for the Transition from Meiosis to Early Embryonic Development. Molecular and Cellular Biology. 39(13). 5 indexed citations

Rahmanto, Aldwin Suryo, Sara Bolin, Holger Weishaupt, et al.. (2016). FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma. The EMBO Journal. 35(20). 2192–2212. 62 indexed citations

Tan, YingMeei, Dahui Sun, Kathleen Klotz‐Noack, et al.. (2014). PP2A-B55β Antagonizes Cyclin E1 Proteolysis and Promotes Its Dysregulation in Cancer. Cancer Research. 74(7). 2006–2014. 18 indexed citations

Rincón, Sonia V. del, Martin Widschwendter, Dahui Sun, et al.. (2014). Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints. Oncogene. 34(15). 1961–1967. 12 indexed citations

Liberal, Vasco, et al.. (2011). Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins. Proceedings of the National Academy of Sciences. 109(8). 2754–2759. 64 indexed citations

10.

Rincón, Sonia V. del, et al.. (2010). Development and Validation of a Method for Profiling Post-Translational Modification Activities Using Protein Microarrays. PLoS ONE. 5(6). e11332–e11332. 22 indexed citations

11.

Akhoondi, Shahab, Linda S. Lindström, Martin Widschwendter, et al.. (2010). Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer. Breast Cancer Research. 12(6). R105–R105. 72 indexed citations

12.

Vashisht, Ajay A., Xinhua Huang, David N. Powers, et al.. (2009). Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase. Science. 326(5953). 718–721. 329 indexed citations

13.

Liberal, Vasco, et al.. (2008). Cyclin-Dependent Kinase-Associated Proteins Cks1 and Cks2 Are Essential during Early Embryogenesis and for Cell Cycle Progression in Somatic Cells. Molecular and Cellular Biology. 28(18). 5698–5709. 101 indexed citations

14.

Klotz, Kathleen, Diana Cepeda, YingMeei Tan, et al.. (2008). SCFFbxw7/hCdc4 targets cyclin E2 for ubiquitin-dependent proteolysis. Experimental Cell Research. 315(11). 1832–1839. 30 indexed citations

15.

Malyukova, Alena, Takeaki Dohda, Natalie von der Lehr, et al.. (2007). The Tumor Suppressor Gene hCDC4 Is Frequently Mutated in Human T-Cell Acute Lymphoblastic Leukemia with Functional Consequences for Notch Signaling. Cancer Research. 67(12). 5611–5616. 148 indexed citations

16.

Keller, Ulrich, Jennifer B. Old, Frank C. Dorsey, et al.. (2007). Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis. The EMBO Journal. 26(10). 2562–2574. 81 indexed citations

17.

Spruck, Charles, María P. De Miguel, Adrian Smith, et al.. (2003). Requirement of Cks2 for the First Metaphase/Anaphase Transition of Mammalian Meiosis. Science. 300(5619). 647–650. 101 indexed citations

18.

Spruck, Charles, William M. Rideout, & Peter A. Jones. (1993). DNA Methylation and cancer. Birkhäuser Basel eBooks. 64. 487–509. 48 indexed citations

19.

Esrig, David, Charles Spruck, Peter W. Nichols, et al.. (1993). p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade, and stage in bladder cancer.. PubMed. 143(5). 1389–97. 404 indexed citations

20.

Jones, Peter A., William M. Rideout, Jiang‐Cheng Shen, Charles Spruck, & Yvonne Tsai. (1992). Methylation, mutation and cancer. BioEssays. 14(1). 33–36. 159 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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