Bruce D. Given

5.1k total citations · 1 hit paper
58 papers, 3.7k citations indexed

About

Bruce D. Given is a scholar working on Epidemiology, Molecular Biology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Bruce D. Given has authored 58 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Epidemiology, 22 papers in Molecular Biology and 16 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Bruce D. Given's work include Hepatitis B Virus Studies (17 papers), RNA Interference and Gene Delivery (11 papers) and Lipid metabolism and disorders (11 papers). Bruce D. Given is often cited by papers focused on Hepatitis B Virus Studies (17 papers), RNA Interference and Gene Delivery (11 papers) and Lipid metabolism and disorders (11 papers). Bruce D. Given collaborates with scholars based in United States, Australia and Canada. Bruce D. Given's co-authors include Eve Van Cauter, K. S. Polonsky, John A Galloway, H. Tillil, Thomas Schluep, Christine Beebe, Ching‐Lung Lai, Robert G. Gish, Stephen Locarnini and Theodore Karrison and has published in prestigious journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Bruce D. Given

58 papers receiving 3.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects.

1988 547 citations K. S. Polonsky, Bruce D. Given et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Bruce D. Given United States	27	1.4k	1.3k	1.2k	1.1k	705	58	3.7k
Yuzo Kodama Japan	28	327 0.2×	1.1k 0.8×	1.4k 1.2×	1.7k 1.5×	903 1.3×	195	4.5k
Jennifer Altomonte Germany	26	697 0.5×	1.8k 1.4×	876 0.7×	693 0.6×	112 0.2×	52	3.6k
Takashi Goto Japan	22	533 0.4×	1.4k 1.1×	342 0.3×	967 0.9×	218 0.3×	92	3.0k
Paul W. Hruz United States	31	329 0.2×	1.1k 0.8×	468 0.4×	555 0.5×	245 0.3×	57	3.0k
Jun Hee Lee South Korea	25	218 0.2×	1.5k 1.2×	412 0.3×	1.0k 0.9×	419 0.6×	71	3.5k
Bermseok Oh South Korea	27	342 0.2×	1.4k 1.0×	282 0.2×	271 0.2×	102 0.1×	149	2.8k
Robert G. Bennett United States	27	439 0.3×	934 0.7×	550 0.5×	310 0.3×	88 0.1×	74	2.5k
Brigitte Debuire France	31	567 0.4×	1.1k 0.9×	259 0.2×	346 0.3×	368 0.5×	95	3.0k
Elena Baixerás Spain	22	439 0.3×	592 0.5×	254 0.2×	314 0.3×	185 0.3×	59	2.8k
Peter G. Traber United States	41	346 0.3×	2.1k 1.6×	1.4k 1.2×	613 0.6×	600 0.9×	83	5.3k

Countries citing papers authored by Bruce D. Given

Since Specialization

Citations

This map shows the geographic impact of Bruce D. Given's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce D. Given with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce D. Given more than expected).

Fields of papers citing papers by Bruce D. Given

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce D. Given. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce D. Given. The network helps show where Bruce D. Given may publish in the future.

Co-authorship network of co-authors of Bruce D. Given

This figure shows the co-authorship network connecting the top 25 collaborators of Bruce D. Given. A scholar is included among the top collaborators of Bruce D. Given based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bruce D. Given. Bruce D. Given is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Watts, Gerald F., Christian Schwabe, Russell L. Scott, et al.. (2023). RNA interference targeting ANGPTL3 for triglyceride and cholesterol lowering: phase 1 basket trial cohorts. Nature Medicine. 29(9). 2216–2223. 65 indexed citations

Strnad, Pavel, Mattias Mandorfer, Gourab Choudhury, et al.. (2022). Fazirsiran for Liver Disease Associated with Alpha ₁ -Antitrypsin Deficiency. New England Journal of Medicine. 387(6). 514–524. 65 indexed citations

Mak, Lung‐Yi, Ed Gane, Christian Schwabe, et al.. (2022). A phase I/II study of ARO-HSD, an RNA interference therapeutic, for the treatment of non-alcoholic steatohepatitis. Journal of Hepatology. 78(4). 684–692. 52 indexed citations

Yuen, Man‐Fung, Danny Ka‐Ho Wong, Thomas Schluep, et al.. (2021). Long-term serological, virological and histological responses to RNA inhibition by ARC-520 in Chinese chronic hepatitis B patients on entecavir treatment. Gut. 71(4). 789–797. 37 indexed citations

Clifton, Peter, David Sullivan, John E. Baker, et al.. (2020). Abstract 12594: Pharmacodynamic Effect of ARO-APOC3, an Investigational Hepatocyte-targeted RNA Interference Therapeutic Targeting Apolipoprotein C3, in Patients With Hypertriglyceridemia and Multifactorial Chylomicronemia. Circulation. 142(Suppl_3). 14 indexed citations

Wooddell, Christine I., Keith Blomenkamp, Ryan M. Peterson, et al.. (2020). Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease. JCI Insight. 5(12). 40 indexed citations

Watts, Gerald F., Christian Schwabe, Russell Scott, et al.. (2020). Abstract 15751: Pharmacodynamic Effect of ARO-ANG3, an Investigational RNA Interference Targeting Hepatic Angiopoietin-like Protein 3, in Patients With Hypercholesterolemia. Circulation. 142(Suppl_3). 34 indexed citations

Fontana, Robert J., Mark Avigan, Harry L.A. Janssen, et al.. (2019). Liver safety assessment in clinical trials of new agents for chronic hepatitis B. Journal of Viral Hepatitis. 27(2). 96–109. 11 indexed citations

Locarnini, Stephen, Bruce D. Given, Thomas Schluep, et al.. (2019). First clinical experience with RNA interference [RNAI]-based triple combination therapy in chronic hepatitis B (CHB): JNJ-73763989 (JNJ-3989), JNJ-56136379 (JNJ-6379) and a nucleos(t)ide analogue (NA). Hepatology. 70(6). 7 indexed citations

10.

Wooddell, Christine I., Man‐Fung Yuen, Henry Lik‐Yuen Chan, et al.. (2017). RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg. Science Translational Medicine. 9(409). 342 indexed citations

11.

Walsh, Renae, R. Hammond, Lilly Yuen, et al.. (2016). Predicting HBsAg Clearance Responses during ARC-520 RNA Interference (RNAI) Therapy Based on HBsAg Epitope Profile Analysis. Journal of Hepatology. 64(2). S602–S602. 3 indexed citations

12.

Gish, Robert G., Man‐Fung Yuen, Henry Lik‐Yuen Chan, et al.. (2015). Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent. Antiviral Research. 121. 97–108. 113 indexed citations

13.

Gish, Robert G., Bruce D. Given, Ching‐Lung Lai, et al.. (2015). Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities. Antiviral Research. 121. 47–58. 188 indexed citations

14.

Tenero, David M., Michael B. Bottorff, Bruce D. Given, et al.. (1989). Pharmacokinetics and pharmacodynamics of dilevalol alone and with cimetidine. Clinical Pharmacology & Therapeutics. 45(2). 170. 4 indexed citations

15.

Given, Bruce D., George Perentesis, Jerry Herron, et al.. (1989). Antihypertensive effect of dilevalol is directly related to dose and plasma concentrations. The American Journal of Cardiology. 63(19). I12–I16. 6 indexed citations

16.

Tenero, David M., Michael B. Bottorff, Bruce D. Given, et al.. (1989). Pharmacokinetics and pharmacodynamics of dilevalol. Clinical Pharmacology & Therapeutics. 46(6). 648–656. 6 indexed citations

17.

Polonsky, K. S., Bruce D. Given, Lawrence J. Hirsch, et al.. (1988). Quantitative study of insulin secretion and clearance in normal and obese subjects.. Journal of Clinical Investigation. 81(2). 435–441. 342 indexed citations

18.

Polonsky, K. S., Bruce D. Given, & Eve Van Cauter. (1988). Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects.. Journal of Clinical Investigation. 81(2). 442–448. 547 indexed citations breakdown →

19.

Polonsky, Kenneth S., Bruce D. Given, Laurence Hirsch, et al.. (1988). Abnormal Patterns of Insulin Secretion in Non-Insulin-Dependent Diabetes Mellitus. New England Journal of Medicine. 318(19). 1231–1239. 430 indexed citations

20.

Cohen, Robert M., Bruce D. Given, Julio Licínio, et al.. (1986). Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism. 35(12). 1137–1146. 51 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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