Brian Hie

9.3k total citations · 5 hit papers
24 papers, 3.7k citations indexed

About

Brian Hie is a scholar working on Molecular Biology, Immunology and Artificial Intelligence. According to data from OpenAlex, Brian Hie has authored 24 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 5 papers in Immunology and 3 papers in Artificial Intelligence. Recurrent topics in Brian Hie's work include RNA and protein synthesis mechanisms (6 papers), Single-cell and spatial transcriptomics (5 papers) and vaccines and immunoinformatics approaches (5 papers). Brian Hie is often cited by papers focused on RNA and protein synthesis mechanisms (6 papers), Single-cell and spatial transcriptomics (5 papers) and vaccines and immunoinformatics approaches (5 papers). Brian Hie collaborates with scholars based in United States, United Kingdom and Slovakia. Brian Hie's co-authors include Bonnie Berger, Bryan D. Bryson, Allan dos Santos Costa, Robert Verkuil, Alexander Rives, Zeming Lin, Zhongkai Zhu, Halil Akin, Ori Kabeli and Salvatore Candido and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Brian Hie

23 papers receiving 3.6k citations

Hit Papers

Evolutionary-scale prediction of ato... 2019 2026 2021 2023 2023 2019 2023 2024 2024 500 1000 1.5k

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Brian Hie United States 17 2.9k 432 325 297 250 24 3.7k
Bruno E. Correia Switzerland 33 3.4k 1.2× 497 1.2× 444 1.4× 697 2.3× 180 0.7× 91 4.7k
Hugo Ceulemans Belgium 30 3.0k 1.0× 789 1.8× 557 1.7× 72 0.2× 235 0.9× 59 4.4k
William S. Hlavacek United States 36 2.9k 1.0× 426 1.0× 79 0.2× 356 1.2× 402 1.6× 103 4.0k
Alexander Rives United States 5 3.4k 1.2× 692 1.6× 388 1.2× 256 0.9× 235 0.9× 8 4.0k
Juergen Haas Germany 33 2.3k 0.8× 312 0.7× 410 1.3× 133 0.4× 303 1.2× 72 4.2k
Tom Sercu United States 7 2.9k 1.0× 586 1.4× 388 1.2× 257 0.9× 186 0.7× 16 3.6k
Rune Linding Denmark 30 5.2k 1.8× 480 1.1× 591 1.8× 168 0.6× 392 1.6× 53 6.1k
Ahmed H. Badran United States 20 5.7k 2.0× 519 1.2× 329 1.0× 173 0.6× 1.4k 5.8× 32 6.8k
David R. Westhead United Kingdom 42 3.5k 1.2× 846 2.0× 432 1.3× 150 0.5× 311 1.2× 120 4.8k
Jaime Prilusky Israel 25 3.9k 1.4× 438 1.0× 859 2.6× 291 1.0× 342 1.4× 40 5.0k

Countries citing papers authored by Brian Hie

Since Specialization
Citations

This map shows the geographic impact of Brian Hie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian Hie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian Hie more than expected).

Fields of papers citing papers by Brian Hie

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian Hie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian Hie. The network helps show where Brian Hie may publish in the future.

Co-authorship network of co-authors of Brian Hie

This figure shows the co-authorship network connecting the top 25 collaborators of Brian Hie. A scholar is included among the top collaborators of Brian Hie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian Hie. Brian Hie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chandrasekaran, Sita S., et al.. (2026). Rapid directed evolution guided by protein language models and epistatic interactions. Science. eaea1820–eaea1820.
2.
Tang, Shaogeng, Soohyun Kim, Varun R. Shanker, et al.. (2025). Utilizing Machine Learning to Improve Neutralization Potency of an HIV-1 Antibody Targeting the gp41 N-Heptad Repeat. ACS Chemical Biology. 20(7). 1470–1480. 1 indexed citations
3.
King, S. B., et al.. (2025). Semantic design of functional de novo genes from a genomic language model. Nature. 649(8097). 749–758. 2 indexed citations
4.
Ku, Ja‐Lok, David W. Romero, Garyk Brixi, et al.. (2025). Systems and Algorithms for Convolutional Multi-Hybrid Language Models at Scale. ArXiv.org. 1 indexed citations
5.
Outeiral, Carlos, et al.. (2024). Generative artificial intelligence for de novo protein design. Current Opinion in Structural Biology. 86. 102794–102794. 25 indexed citations
6.
Shanker, Varun R., Theodora U. J. Bruun, Brian Hie, & Peter S. Kim. (2024). Unsupervised evolution of protein and antibody complexes with a structure-informed language model. Science. 385(6704). 46–53. 53 indexed citations breakdown →
7.
Hie, Brian, Soochi Kim, Thomas A. Rando, Bryan D. Bryson, & Bonnie Berger. (2024). Scanorama: integrating large and diverse single-cell transcriptomic datasets. Nature Protocols. 19(8). 2283–2297. 8 indexed citations
8.
Smirnov, Asya, Sthefany M. Chavez, Brian Hie, et al.. (2024). BHLHE40 Regulates Myeloid Cell Polarization through IL-10–Dependent and –Independent Mechanisms. The Journal of Immunology. 212(11). 1766–1781. 1 indexed citations
9.
Hie, Brian, Varun R. Shanker, Duo Xu, et al.. (2023). Efficient evolution of human antibodies from general protein language models. Nature Biotechnology. 42(2). 275–283. 205 indexed citations breakdown →
10.
Lin, Zeming, Halil Akin, Roshan Rao, et al.. (2023). Evolutionary-scale prediction of atomic-level protein structure with a language model. Science. 379(6637). 1123–1130. 1968 indexed citations breakdown →
11.
Maher, M. Cyrus, István Bartha, Steven Weaver, et al.. (2022). Predicting the mutational drivers of future SARS-CoV-2 variants of concern. Science Translational Medicine. 14(633). eabk3445–eabk3445. 99 indexed citations
12.
Hie, Brian, Kevin Yang, & Peter S. Kim. (2022). Evolutionary velocity with protein language models predicts evolutionary dynamics of diverse proteins. Cell Systems. 13(4). 274–285.e6. 73 indexed citations
13.
Hie, Brian, Ellen D. Zhong, Bonnie Berger, & Bryan D. Bryson. (2021). Learning the language of viral evolution and escape. Science. 371(6526). 284–288. 183 indexed citations
14.
Singh, Rohit, et al.. (2021). Schema: metric learning enables interpretable synthesis of heterogeneous single-cell modalities. Genome biology. 22(1). 131–131. 27 indexed citations
15.
Hie, Brian, Joshua M. Peters, Sarah K. Nyquist, et al.. (2020). Computational Methods for Single-Cell RNA Sequencing. 3(1). 339–364. 57 indexed citations
16.
Hie, Brian, Ellen D. Zhong, Bryan D. Bryson, & Bonnie Berger. (2020). Learning Mutational Semantics. Neural Information Processing Systems. 33. 9109–9121. 2 indexed citations
17.
Hie, Brian, et al.. (2019). Geometric Sketching Compactly Summarizes the Single-Cell Transcriptomic Landscape. Cell Systems. 8(6). 483–493.e7. 80 indexed citations
18.
Tehranchi, Ashley K., Brian Hie, Michael Dacre, et al.. (2019). Fine-mapping cis-regulatory variants in diverse human populations. eLife. 8. 46 indexed citations
19.
Hie, Brian, Bryan D. Bryson, & Bonnie Berger. (2019). Efficient integration of heterogeneous single-cell transcriptomes using Scanorama. Nature Biotechnology. 37(6). 685–691. 464 indexed citations breakdown →
20.
Hie, Brian, Hyunghoon Cho, & Bonnie Berger. (2018). Realizing private and practical pharmacological collaboration. Science. 362(6412). 347–350. 49 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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