Arthur L. Horwich

24.6k total citations · 8 hit papers
157 papers, 19.9k citations indexed

About

Arthur L. Horwich is a scholar working on Molecular Biology, Materials Chemistry and Clinical Biochemistry. According to data from OpenAlex, Arthur L. Horwich has authored 157 papers receiving a total of 19.9k indexed citations (citations by other indexed papers that have themselves been cited), including 128 papers in Molecular Biology, 63 papers in Materials Chemistry and 17 papers in Clinical Biochemistry. Recurrent topics in Arthur L. Horwich's work include Heat shock proteins research (85 papers), Protein Structure and Dynamics (77 papers) and Enzyme Structure and Function (63 papers). Arthur L. Horwich is often cited by papers focused on Heat shock proteins research (85 papers), Protein Structure and Dynamics (77 papers) and Enzyme Structure and Function (63 papers). Arthur L. Horwich collaborates with scholars based in United States, United Kingdom and Germany. Arthur L. Horwich's co-authors include Bernd Bukau, Wayne A. Fenton, Jonathan S. Weissman, Paul B. Sigler, F. Ulrich Hartl, George W. Farr, Zhaohui Xu, Jörg Martin, František Kalousek and Hays S. Rye and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Arthur L. Horwich

155 papers receiving 19.5k citations

Hit Papers

The Hsp70 and Hsp60 Chaperone Machines 1989 2026 2001 2013 1998 2006 1994 1997 1989 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Hsp70 and Hsp60 Chaperone Machines
    1998 2.3k citations Arthur L. Horwich et al. Cell profile →
  2. Molecular Chaperones and Protein Quality Control
    2006 1.2k citations Jonathan S. Weissman, Arthur L. Horwich et al. Cell profile →
  3. The crystal structure of the bacterial chaperonln GroEL at 2.8 Å
    1994 1.1k citations Arthur L. Horwich et al. Nature profile →
  4. The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex
    1997 1.0k citations Arthur L. Horwich et al. Nature profile →
  5. Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
    1989 781 citations F. Ulrich Hartl, Jörg Martin et al. Nature profile →
  6. Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate
    1991 748 citations Jörg Martin, Thomas Langer et al. Nature profile →
  7. Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis
    1989 559 citations Arthur L. Horwich, F. Ulrich Hartl et al. Nature profile →
  8. Mechanisms of protein folding
    2001 383 citations Arthur L. Horwich et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Arthur L. Horwich United States 64 17.3k 6.8k 2.8k 2.1k 1.4k 157 19.9k
Stephan Grzesiek Switzerland 66 22.5k 1.3× 6.0k 0.9× 2.6k 0.9× 1.9k 0.9× 2.2k 1.5× 171 29.5k
Manajit Hayer‐Hartl Germany 53 15.6k 0.9× 3.6k 0.5× 3.5k 1.3× 1.6k 0.8× 1.2k 0.8× 98 18.1k
Gerald D. Fasman United States 64 22.3k 1.3× 4.3k 0.6× 2.3k 0.8× 1.5k 0.7× 2.2k 1.5× 234 30.2k
Rainer Jaenicke Germany 61 13.0k 0.8× 6.1k 0.9× 2.5k 0.9× 639 0.3× 1.1k 0.8× 312 15.9k
Donald M. Engelman United States 85 21.0k 1.2× 2.0k 0.3× 2.3k 0.8× 1.4k 0.7× 1.8k 1.3× 250 25.8k
Johannes Büchner Germany 91 25.7k 1.5× 5.4k 0.8× 4.7k 1.7× 4.0k 2.0× 1.4k 1.0× 293 29.8k
Luís Serrano Spain 76 19.6k 1.1× 5.5k 0.8× 2.5k 0.9× 778 0.4× 2.6k 1.8× 314 23.5k
Luke M. Rice United States 31 15.0k 0.9× 4.0k 0.6× 3.8k 1.4× 1.2k 0.6× 2.2k 1.6× 57 19.2k
H. Jane Dyson United States 94 31.4k 1.8× 10.1k 1.5× 4.4k 1.6× 1.7k 0.8× 2.5k 1.7× 305 37.3k
Geerten W. Vuister Netherlands 46 15.8k 0.9× 3.8k 0.6× 2.0k 0.7× 1.3k 0.6× 1.6k 1.1× 120 20.2k

Countries citing papers authored by Arthur L. Horwich

Since Specialization
Citations

This map shows the geographic impact of Arthur L. Horwich's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arthur L. Horwich with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arthur L. Horwich more than expected).

Fields of papers citing papers by Arthur L. Horwich

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arthur L. Horwich. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arthur L. Horwich. The network helps show where Arthur L. Horwich may publish in the future.

Co-authorship network of co-authors of Arthur L. Horwich

This figure shows the co-authorship network connecting the top 25 collaborators of Arthur L. Horwich. A scholar is included among the top collaborators of Arthur L. Horwich based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Arthur L. Horwich. Arthur L. Horwich is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Fenton, Wayne A., et al.. (2017). Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice. Proceedings of the National Academy of Sciences. 114(15). E3139–E3148. 13 indexed citations
2.
Ambrose, Andrew J., et al.. (2015). Unfolded DapA forms aggregates when diluted into free solution, confounding comparison with folding by the GroEL/GroES chaperonin system. FEBS Letters. 589(4). 497–499. 4 indexed citations
3.
Bandyopadhyay, Urmi, et al.. (2014). Production of RNA for Transcriptomic Analysis from Mouse Spinal Cord Motor Neuron Cell Bodies by Laser Capture Microdissection. Journal of Visualized Experiments. 1 indexed citations
4.
Clare, Daniel K., Daven Vasishtan, Scott M. Stagg, et al.. (2012). ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the GroEL Chaperonin. Cell. 149(1). 113–123. 143 indexed citations
5.
Horwich, Arthur L.. (2012). Chaperonin-mediated protein folding 2. ˜The œbiomedical & life sciences collection.. 2012(9). e1003442–e1003442. 1 indexed citations
6.
Koculi, Eda, Reto Horst, Arthur L. Horwich, & Kurt Wüthrich. (2011). Nuclear magnetic resonance spectroscopy with the stringent substrate rhodanese bound to the single‐ring variant SR1 of the E. coli chaperonin GroEL. Protein Science. 20(8). 1380–1386. 17 indexed citations
7.
Chapman, Eli, George W. Farr, Renata Usaite, et al.. (2006). Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL. Proceedings of the National Academy of Sciences. 103(43). 15800–15805. 119 indexed citations
8.
Horst, Reto, Eric B. Bertelsen, Jocelyne Fiaux, et al.. (2005). Direct NMR observation of a substrate protein bound to the chaperonin GroEL. Proceedings of the National Academy of Sciences. 102(36). 12748–12753. 92 indexed citations
9.
Fenton, Wayne A., et al.. (2005). Loops in the Central Channel of ClpA Chaperone Mediate Protein Binding, Unfolding, and Translocation. Cell. 121(7). 1029–1041. 192 indexed citations
10.
Motojima, Fumihiro, Charu Chaudhry, Wayne A. Fenton, George W. Farr, & Arthur L. Horwich. (2004). Substrate polypeptide presents a load on the apical domains of the chaperonin GroEL. Proceedings of the National Academy of Sciences. 101(42). 15005–15012. 67 indexed citations
11.
Horwich, Arthur L.. (2002). Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions. Journal of Clinical Investigation. 110(9). 1221–1232. 167 indexed citations
12.
Horwich, Arthur L.. (2002). Protein folding in the cell. Academic Press eBooks. 1 indexed citations
13.
Chaudhuri, Tapan K., George W. Farr, Wayne A. Fenton, Sabine Rospert, & Arthur L. Horwich. (2001). GroEL/GroES-Mediated Folding of a Protein Too Large to Be Encapsulated. Cell. 107(2). 235–246. 141 indexed citations
14.
Farr, George W., Krystyna Furtak, Neil A. Ranson, et al.. (2000). Multivalent Binding of Nonnative Substrate Proteins by the Chaperonin GroEL. Cell. 100(5). 561–573. 154 indexed citations
15.
Horwich, Arthur L.. (1995). Molecular Chaperones: Resurrection or destruction?. Current Biology. 5(5). 455–458. 23 indexed citations
16.
Weissman, Jonathan S., Yechezkel Kashi, Wayne A. Fenton, & Arthur L. Horwich. (1994). GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms. Cell. 78(4). 693–702. 309 indexed citations
17.
Horwich, Arthur L., Keith R. Willison, Nicholas J. Cowan, et al.. (1993). Protein folding in the cell : functions of two families of molecular chaperone, hsp 60 and TF55-TCP1. Discussion. 339(1289). 313–326. 2 indexed citations
18.
Martin, Jörg, et al.. (1991). Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate. Nature. 352(6330). 36–42. 748 indexed citations breakdown →
19.
Yamaizumi, Masaru, Arthur L. Horwich, & Frank H. Ruddle. (1983). Expression and Stabilization of Microinjected Plasmids Containing the Herpes Simplex Virus Thymidine Kinase Gene and Polyoma Virus DNA in Mouse Cells. Molecular and Cellular Biology. 3(4). 511–522. 15 indexed citations
20.
Riely, Caroline A., Douglas R. LaBrecque, Cameron N. Ghent, Arthur L. Horwich, & Gerald Klatskin. (1978). A father and son with cholestasis and peripheral pulmonic stenosis. The Journal of Pediatrics. 92(3). 406–411. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Stephan Grzesiek Breakdown of academic impact, for papers by Manajit Hayer‐Hartl Breakdown of academic impact, for papers by Gerald D. Fasman Breakdown of academic impact, for papers by Rainer Jaenicke Breakdown of academic impact, for papers by Donald M. Engelman Breakdown of academic impact, for papers by Johannes Büchner Breakdown of academic impact, for papers by Luís Serrano Breakdown of academic impact, for papers by Luke M. Rice Breakdown of academic impact, for papers by H. Jane Dyson Breakdown of academic impact, for papers by Geerten W. Vuister
Rankless by CCL
2026