Amy Shen

2.3k total citations · 1 hit paper
43 papers, 1.7k citations indexed

About

Amy Shen is a scholar working on Molecular Biology, Radiology, Nuclear Medicine and Imaging and Genetics. According to data from OpenAlex, Amy Shen has authored 43 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Molecular Biology, 21 papers in Radiology, Nuclear Medicine and Imaging and 9 papers in Genetics. Recurrent topics in Amy Shen's work include Viral Infectious Diseases and Gene Expression in Insects (30 papers), Protein purification and stability (23 papers) and Monoclonal and Polyclonal Antibodies Research (21 papers). Amy Shen is often cited by papers focused on Viral Infectious Diseases and Gene Expression in Insects (30 papers), Protein purification and stability (23 papers) and Monoclonal and Polyclonal Antibodies Research (21 papers). Amy Shen collaborates with scholars based in United States, Germany and France. Amy Shen's co-authors include Natarajan Vijayasankaran, Róbert Kiss, Feng Li, Ashraf Amanullah, Zhilan Hu, John C. Joly, Bradley Snedecor, Inn H. Yuk, Michael W. Laird and Brad Snedecor and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Analytical Chemistry and Genetics.

In The Last Decade

Amy Shen

41 papers receiving 1.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cell culture processes for monoclonal antibody production

2010 504 citations Feng Li, Natarajan Vijayasankaran et al. mAbs profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Amy Shen United States	23	1.6k	788	246	166	164	43	1.7k
Andrew J. Racher United Kingdom	23	1.6k 1.0×	563 0.7×	406 1.7×	150 0.9×	213 1.3×	42	1.8k
Rashmi Kshirsagar United States	17	1.1k 0.7×	300 0.4×	161 0.7×	100 0.6×	224 1.4×	26	1.2k
Helene Faustrup Kildegaard Denmark	27	2.0k 1.3×	386 0.5×	579 2.4×	179 1.1×	134 0.8×	53	2.1k
Michael J. Gramer United States	13	998 0.6×	605 0.8×	110 0.4×	156 0.9×	116 0.7×	19	1.2k
Roland Wagner Germany	20	1.2k 0.7×	207 0.3×	246 1.0×	66 0.4×	156 1.0×	34	1.4k
Natarajan Vijayasankaran United States	10	1.0k 0.7×	368 0.5×	110 0.4×	68 0.4×	167 1.0×	13	1.1k
Maureen Spearman Canada	17	737 0.5×	318 0.4×	87 0.4×	87 0.5×	54 0.3×	30	910
Yariv Mazor United States	16	860 0.5×	669 0.8×	58 0.2×	215 1.3×	54 0.3×	24	1.3k
Patrick Hossler United States	12	851 0.5×	487 0.6×	86 0.3×	48 0.3×	47 0.3×	14	909
Björn G. Voldborg Denmark	15	710 0.4×	195 0.2×	161 0.7×	251 1.5×	53 0.3×	31	1.0k

Countries citing papers authored by Amy Shen

Since Specialization

Citations

This map shows the geographic impact of Amy Shen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Amy Shen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Amy Shen more than expected).

Fields of papers citing papers by Amy Shen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Amy Shen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Amy Shen. The network helps show where Amy Shen may publish in the future.

Co-authorship network of co-authors of Amy Shen

This figure shows the co-authorship network connecting the top 25 collaborators of Amy Shen. A scholar is included among the top collaborators of Amy Shen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Amy Shen. Amy Shen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Chen, Dayue, et al.. (2023). Recombinant adeno‐associated virus production evaluation in Chinese hamster ovary cells. Biotechnology and Bioengineering. 121(1). 395–402. 5 indexed citations

Lam, Cynthia, Dejin Zhan, Danming Tang, et al.. (2023). Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth. Biotechnology Progress. 39(3). e3337–e3337. 1 indexed citations

Barnard, Gavin C., Michelle Zhou, Amy Shen, Inn H. Yuk, & Michael W. Laird. (2023). Utilizing targeted integration CHO pools to potentially accelerate the GMP manufacturing of monoclonal and bispecific antibodies. Biotechnology Progress. 40(1). e3399–e3399. 5 indexed citations

Tang, Danming, Cynthia Lam, Amy Shen, et al.. (2022). Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study. Biotechnology Progress. 38(6). e3290–e3290. 1 indexed citations

Duan, Dana, et al.. (2021). A ribonucleoprotein‐based decaplex CRISPR /Cas9 knockout strategy for CHO host engineering. Biotechnology Progress. 38(1). 6 indexed citations

Sun, Yue, Hao Cai, Zhilan Hu, et al.. (2020). Balancing the Affinity and Pharmacokinetics of Antibodies by Modulating the Size of Charge Patches on Complementarity-Determining Regions. Journal of Pharmaceutical Sciences. 109(12). 3690–3696. 4 indexed citations

Hu, Zhilan, Danming Tang, Shahram Misaghi, et al.. (2017). Evaluation of heavy chain C‐terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells. Biotechnology Progress. 33(3). 786–794. 14 indexed citations

Shatz-Binder, Whitney, George Dutina, Athena W. Wong, et al.. (2016). An efficient route to bispecific antibody production using single-reactor mammalian co-culture. mAbs. 8(8). 1487–1497. 19 indexed citations

Taylor, Matthew B., et al.. (2016). Multi-locus Genotypes Underlying Temperature Sensitivity in a Mutationally Induced Trait. PLoS Genetics. 12(3). e1005929–e1005929. 17 indexed citations

10.

Jiang, Guoying, Christopher Yu, Daniela Bumbaca Yadav, et al.. (2016). Evaluation of Heavy-Chain C-Terminal Deletion on Product Quality and Pharmacokinetics of Monoclonal Antibodies. Journal of Pharmaceutical Sciences. 105(7). 2066–2072. 23 indexed citations

11.

Zhou, Meixia, et al.. (2014). Complete Knockout of the Lactate Dehydrogenase A Gene is Lethal in Pyruvate Dehydrogenase Kinase 1, 2, 3 Down-Regulated CHO Cells. Molecular Biotechnology. 56(9). 833–838. 15 indexed citations

12.

Crawford, Yongping, Michelle Zhou, Zhilan Hu, et al.. (2013). Fast identification of reliable hosts for targeted cell line development from a limited‐genome screening using combined φC31 integrase and CRE‐Lox technologies. Biotechnology Progress. 29(5). 1307–1315. 41 indexed citations

13.

Sreedhara, Alavattam, Charlene Li, Frank Macchi, et al.. (2012). Role of Surface Exposed Tryptophan as Substrate Generators for the Antibody Catalyzed Water Oxidation Pathway. Molecular Pharmaceutics. 10(1). 278–288. 45 indexed citations

14.

Chung, Shan, Valerie Quarmby, Xiaoying Gao, et al.. (2012). Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities. mAbs. 4(3). 326–340. 101 indexed citations

15.

Zhou, Meixia, Yongping Crawford, Jack K. Tung, et al.. (2011). Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases. Journal of Biotechnology. 153(1-2). 27–34. 117 indexed citations

16.

Yuk, Inn H., Boyan Zhang, George Dutina, et al.. (2011). Controlling glycation of recombinant antibody in fed‐batch cell cultures. Biotechnology and Bioengineering. 108(11). 2600–2610. 64 indexed citations

17.

Li, Charlene, Amy Shen, Hongbin Liu, et al.. (2010). Detecting low level sequence variants in recombinant monoclonal antibodies. mAbs. 2(3). 285–298. 63 indexed citations

18.

Li, Feng, Natarajan Vijayasankaran, Amy Shen, Róbert Kiss, & Ashraf Amanullah. (2010). Cell culture processes for monoclonal antibody production. mAbs. 2(5). 466–479. 504 indexed citations breakdown →

19.

Guo, Donglin, Albert Gao, David A. Michels, et al.. (2010). Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells. Biotechnology and Bioengineering. 107(1). 163–171. 57 indexed citations

20.

Shen, Amy, et al.. (2001). [Cloning and expression of VHB gene in D-arabitol producing yeast].. PubMed. 41(3). 315–9. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact