Alfredo Castro

2.7k total citations · 2 hit papers
17 papers, 1.7k citations indexed

About

Alfredo Castro is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Alfredo Castro has authored 17 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 7 papers in Molecular Biology, 5 papers in Oncology and 4 papers in Cell Biology. Recurrent topics in Alfredo Castro's work include Cancer Immunotherapy and Biomarkers (3 papers), Tryptophan and brain disorders (3 papers) and Immune cells in cancer (3 papers). Alfredo Castro is often cited by papers focused on Cancer Immunotherapy and Biomarkers (3 papers), Tryptophan and brain disorders (3 papers) and Immune cells in cancer (3 papers). Alfredo Castro collaborates with scholars based in United States, China and Canada. Alfredo Castro's co-authors include Vito J. Palombella, Lenny Dang, Julian Adams, Nicholas Mitsiades, Kenneth C. Anderson, Toshiaki Hayashi, Teru Hideshima, Nikhil C. Munshi, Paul G. Richardson and Dharminder Chauhan and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and Blood.

In The Last Decade

Alfredo Castro

16 papers receiving 1.7k citations

Hit Papers

NF-κB as a Therapeutic Target in Multiple Myeloma 2002 2026 2010 2018 2002 2020 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. NF-κB as a Therapeutic Target in Multiple Myeloma
    2002 752 citations Teru Hideshima, Dharminder Chauhan et al. Journal of Biological Chemistry profile →
  2. Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine
    2020 335 citations Luís Felipe Campesato, Sadna Budhu et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alfredo Castro United States 9 1.1k 468 425 377 363 17 1.7k
Ian N. Foltz United States 21 978 0.9× 465 1.0× 582 1.4× 215 0.6× 145 0.4× 36 1.9k
Daniela Barilá Italy 26 1.4k 1.3× 472 1.0× 239 0.6× 239 0.6× 254 0.7× 50 1.9k
Teresa Maguire Ireland 16 746 0.7× 689 1.5× 120 0.3× 167 0.4× 867 2.4× 26 1.6k
James L. Clements United States 20 1.0k 0.9× 429 0.9× 1.2k 2.9× 225 0.6× 166 0.5× 41 2.3k
Paul J. Coffer Netherlands 18 1.4k 1.3× 353 0.8× 452 1.1× 246 0.7× 272 0.7× 27 2.1k
Gargi D. Basu United States 20 793 0.7× 977 2.1× 510 1.2× 40 0.1× 344 0.9× 53 2.0k
Teresa Ezponda United States 15 1.4k 1.3× 323 0.7× 661 1.6× 210 0.6× 393 1.1× 29 2.1k
Ron de Jong United States 19 1.1k 1.0× 289 0.6× 179 0.4× 224 0.6× 78 0.2× 33 1.6k
Kian Leong Lee Singapore 23 1.4k 1.3× 349 0.7× 282 0.7× 115 0.3× 562 1.5× 40 2.0k
Alison O’Mahony United States 11 665 0.6× 247 0.5× 462 1.1× 256 0.7× 249 0.7× 19 1.2k

Countries citing papers authored by Alfredo Castro

Since Specialization
Citations

This map shows the geographic impact of Alfredo Castro's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alfredo Castro with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alfredo Castro more than expected).

Fields of papers citing papers by Alfredo Castro

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alfredo Castro. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alfredo Castro. The network helps show where Alfredo Castro may publish in the future.

Co-authorship network of co-authors of Alfredo Castro

This figure shows the co-authorship network connecting the top 25 collaborators of Alfredo Castro. A scholar is included among the top collaborators of Alfredo Castro based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alfredo Castro. Alfredo Castro is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

17 of 17 papers shown
1.
Castro, Alfredo, Kijung Sung, Ruinan Shen, et al.. (2023). Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy. Neurobiology of Disease. 178. 106010–106010. 6 indexed citations
2.
Punkosdy, George A., Jill Cavanaugh, Collin M. Bantle, et al.. (2023). Abstract 1646: IK-930, a paralog-selective TEAD inhibitor for treating YAP/TAZ-TEAD dependent cancers. Cancer Research. 83(7_Supplement). 1646–1646. 8 indexed citations
3.
McGovern, Karen, Alfredo Castro, Jill Cavanaugh, et al.. (2022). Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression. Molecular Cancer Therapeutics. 21(8). 1261–1272. 27 indexed citations
4.
Amidon, Benjamin, Wilmin Bartolini, Karen McGovern, et al.. (2022). Abstract 2156: IK-930 is a novel TEAD inhibitor for the treatment of cancers harboring mutations in the Hippo signal transduction pathway. Cancer Research. 82(12_Supplement). 2156–2156. 14 indexed citations
5.
Amidon, Benjamin, Jill Cavanaugh, Katie O’Callaghan, et al.. (2021). Abstract P216: IK-930 mediated TEAD inhibition decreases and delays tumor growth and enhances targeted apoptosis in lung and colon cancer xenografts when combined with MEK or EGFR inhibitors. Molecular Cancer Therapeutics. 20(12_Supplement). P216–P216. 7 indexed citations
6.
Campesato, Luís Felipe, Sadna Budhu, Jeremy H. Tchaicha, et al.. (2020). Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine. Nature Communications. 11(1). 4011–4011. 335 indexed citations breakdown →
7.
McGovern, Karen, Alfredo Castro, Jill Cavanaugh, et al.. (2020). 448 Discovery of clinical candidate IK-175, a selective orally active AHR antagonist. Regular and Young Investigator Award Abstracts. A272.1–A272. 3 indexed citations
8.
Tchaicha, Jeremy H., Sílvia Coma, Jill Cavanaugh, et al.. (2019). Abstract 4131: Overcoming aryl hydrocarbon receptor mediated tumor immunosuppression. Cancer Research. 79(13_Supplement). 4131–4131. 1 indexed citations
9.
Vacca, Joseph P., et al.. (2018). CYT01B, a Novel RAD51 Inhibitor, Act Synergistically with Both Targeted and Chemotherapeutic Anti-Cancer Agents. Blood. 132(Supplement 1). 3963–3963. 5 indexed citations
10.
Brophy, Erin, James Conley, Patrick J. O’Hearn, et al.. (2013). Abstract 1891: Pharmacological target validation studies of fatty acid synthase in carcinoma using the potent, selective and orally bioavailable inhibitor IPI-9119.. Cancer Research. 73(8_Supplement). 1891–1891. 5 indexed citations
11.
Tremblay, Martin, Karen McGovern, Margaret Read, & Alfredo Castro. (2010). New developments in the discovery of small molecule Hedgehog pathway antagonists. Current Opinion in Chemical Biology. 14(3). 428–435. 25 indexed citations
12.
Tremblay, Martin, et al.. (2009). Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy. Expert Opinion on Therapeutic Patents. 19(8). 1039–1056. 61 indexed citations
13.
Castro, Alfredo, Lenny Dang, François Soucy, et al.. (2003). Novel IKK inhibitors: β-carbolines. Bioorganic & Medicinal Chemistry Letters. 13(14). 2419–2422. 211 indexed citations
14.
Hideshima, Teru, Dharminder Chauhan, Paul G. Richardson, et al.. (2002). NF-κB as a Therapeutic Target in Multiple Myeloma. Journal of Biological Chemistry. 277(19). 16639–16647. 752 indexed citations breakdown →
15.
Lin, Ko‐Chung, Lillian T. Chong, Craig Zimmerman, et al.. (1999). Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses. Journal of Medicinal Chemistry. 42(5). 920–934. 177 indexed citations
16.
Lin, Ko‐Chung & Alfredo Castro. (1998). Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents. Current Opinion in Chemical Biology. 2(4). 453–457. 79 indexed citations
17.
Castro, Alfredo & Nobuo Monji. (1983). Assays of drugs by immunological methods.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Ian N. Foltz Breakdown of academic impact, for papers by Daniela Barilá Breakdown of academic impact, for papers by Teresa Maguire Breakdown of academic impact, for papers by James L. Clements Breakdown of academic impact, for papers by Paul J. Coffer Breakdown of academic impact, for papers by Gargi D. Basu Breakdown of academic impact, for papers by Teresa Ezponda Breakdown of academic impact, for papers by Ron de Jong Breakdown of academic impact, for papers by Kian Leong Lee Breakdown of academic impact, for papers by Alison O’Mahony
Rankless by CCL
2026